• Title/Summary/Keyword: ORA

Search Result 57, Processing Time 0.024 seconds

Biochemical Studies on Some Hypoglycemic Agents (II) Effect of Calligonum comosum extract

  • El-Hawary, Z.M.;Kholief, T.S.
    • Archives of Pharmacal Research
    • /
    • v.13 no.1
    • /
    • pp.113-116
    • /
    • 1990
  • People in some tropical countries used to use some plant extracts in folklore medicine as treatment of diabetes melitus. Of these plants is Calligonum comsum ("orta"). The present work deals with the biochemical effects of the whole plant water extract given orally to the albino rats, normals and alloxan diabetics, as to fulfil its hypoglycemic effects on rats. The results showed that "orta" extract produced a hypoglycemic effect indicated by the decrease in blood sugar level. It was observed that the diabetic state in rats treated with 300 mg/kg body weight of "orta" extract, was alleviated, showeing normal levels of blood glucose, liver fat and cholesterol contents. Liver proteins were still below the normal level in the rats. Gibenclamide, a hypoglycemic drug, was used for comparison with "ora" extract. Although it did alleviate the diabetic state, yet the liver fat and cholesterol contents were still higher than those of normal. Also the liver proteins were lower than the control levels.

  • PDF

Spore-Pollen Specters of Deed Turnn Lake Terrace, Darkhad Depression, Mongolia

  • Punsalpaamuu, G.
    • The Korean Journal of Quaternary Research
    • /
    • v.17 no.2
    • /
    • pp.39-41
    • /
    • 2003
  • Pollen and spores as well as their morphological characteristics are biological stability materials in which contains historical information about vegetation and climate changes. As noted researcher Neishtadt in 1971, the lake and swamp deposits were developed only in Holocene period. The geological history of Darkhad depression which is situated in the Northern end of Mongolia from ancient time become under scientific interest of many researchers. Our investigation was focused on pollen analysis of lake sediment of Darkhad depression which caused bottom of paleolake. In Mongolia the palynology science is beginning to develop since 1990 and in 2000 the laboratory of palynology was established at the department of Biology, State Pedagogical University of Mongolia. Researchers from this laboratory working on pollen morphology of present flora in order to classify plants taxonomy. Another part of our investigation is mellitopalynology, which is studying of pollen grains in a honey. Although, this research has been extending by pollen analysis of sediment and lake deposits in past few years on the basis of high sensitive microscope and modem technology.

  • PDF

Evaluation of Damage Range Variation Based on Operation System of Chlorine Facility in Water Purification Plant using KORA (KORA를 활용한 정수장 염소 취급시설의 운영조건에 따른 피해범위 변화 평가)

  • Kwak, Sollim;Lim, Hyeongjun;Ryu, Taekwon;Choi, Woosoo;Jung, Jinhee;Lee, Jieun;Kim, Jungkon;Lee, Yeonhee;Ryu, Jisung;Yoon, Junheon;Yoon, Yi;Lee, Jinseon
    • Journal of the Korean Institute of Gas
    • /
    • v.22 no.3
    • /
    • pp.84-90
    • /
    • 2018
  • We researched the way to minimize the damage when the chlorine-leak accident take place in a purification plant. Since the level of risk based on the Off-site Risk Assessment(ORA) is a combination of proportional to the number of residents in the damaged area and frequency of accidents, we suggested the adequate conditions to reduce the number of residents in the damaged area by means of the operating temperature of a handling facility, installation of a emergency shut-off valve, and the analysis of the variation of the damaging range in accordance with the type of enclosure. The coverage of damage was calculated by the 'KORA(Korea Off-site Risk Assessment Supporting Tool) program. The research shows that the lower operating temperature gets, the more emergency shut-off valve being installed and the higher enclosure level of facility becomes, the extent of damage gets decreased. The decreasing rate of worst case was 17.6%, 71%, 34.5% respectively, the decreasing rate of alternative case was 31.6%, 69.0%, 34.8% respectively.

Risk Management for Ammonia Unloading and Storage Tank Facility (암모니아 입하 및 저장시설에서의 위험도 관리)

  • Jeong, Yun Seo;Woo, In Sung;Lim, Jong Woo
    • Journal of the Korean Institute of Gas
    • /
    • v.21 no.5
    • /
    • pp.95-103
    • /
    • 2017
  • A lot of hazardous materials have been used for product processing and utility plant. Many accidents including toxic release, fire and explosions occur in the ammonia related facility and plant. Various safety and environment management program including PSM, SMS, ORA etc. are being implemented for risk management and accident prevention in the production industry. Also much study and research have been carried about risk assessment of accident scenario in the academic and research area. In this paper, firstly risk level was assessed by using a typically used KORA program and LOPA PFD method for the selected ammonia unloading and storage facility. And then risk reduction measures for the risk assessed facility were studied in 3 aspects and some measures were proposed. Those Risk Reduction measures are including a leak detection and emergency isolation, water spray, dilution tank, dike and trench, scattering protection in hardware impovement aspect, and a applicable risk criteria, conditional modifier for existing LOPA PFD, alternative supporting modeling program in risk estimation methodology aspect, and last RBPS(Risk Based Process Safety) program, re-doing of process hazard analysis, management system compliance audit in managerial activity aspect.

Optimization of Flip Angle at Head & Neck MR Angiography using Gadoteridol (Gadoteridol을 이용한 Head & Neck MR Angiography에서의 적정 Flip Angle)

  • Jeong, Hyunkeun;Kim, Mingi;Song, Jaejun;Nam, Kichang;Choi, Hyunsung;Jeong, Hyundo;Kim, Hochul
    • Journal of the Institute of Electronics and Information Engineers
    • /
    • v.53 no.3
    • /
    • pp.151-159
    • /
    • 2016
  • In this research, we tried to suggest moderate FA(Flip Angle) for CE(Contrast Enhnaced)-Head&Neck MR Angiography with Gadoteridol. For this study, we did test MR phantom and clinical study according to FA change. After that, quantitative analysis was progressed. The results of MR phantom study were as follow: RSP(Reaction Starting Point)was recorded within 300~400 mmol. MPSI(Max Peak Signal Intensity) was 2,086, 3,705, 5,109, 6,194, 7.096, 7,192 [a.u]. MPP(Max Peak Point) was shown at 30, 50, 50, 40, 50, 40 mmol. IRMPSI(Increase Rate of MPSI) was 77.6%, 37.9%, 21.2%, 14.6%, 1.4% as increasing of FA. The results of clinical study were as follow SICB(Signal Intensity of Carotid artery Bifurcation) was recorded respectively 392.5, 4165.2, 4270, 3502.2, 3263.7, 3119.6 [a.u]. ORA(Occurence Rate of Artifact) was increased as 0, 0, 20, 40, 50, 70%. According to this research, we are not only able to assure that increase of FA can be effect on H1 spin's SI(Signal Intensity) which was combined with gadolinium agent, but also be effect on artifact rate in blood vessel. In clinical field, we expect that CE-Head&Neck MR Angiography can be performed in a practical way with this research.

A Contribution to the Pollen Morphology of Hippocastanaceae (칠엽수과(科) 화분(花粉)의 형태학적(形態學的) 연구(硏究))

  • Kim, Kae-Hwan;Aravanopoulos, F.A.;Zsuffa, L.
    • Journal of Korean Society of Forest Science
    • /
    • v.86 no.2
    • /
    • pp.251-258
    • /
    • 1997
  • The pollen morphology of 20 species and one variety of the two genera of Hippocastanaceae was investigated by LM, SEM and TEM. The pollen grains of this family are monads, prolate to subprolate, isopolar, radially symmetrical, 3-colporate or 3-colpate and ora is circular or lolongate. Sculpture pattern is distinctly striate or spinulose, Brae in various directions. Based on the aperture types and sculpture patterns three major pollen types of this family are discernible : hippocastanum, indica, and punduana.

  • PDF

Occurence of Chemical Resistance and Control of Dollar Spot Caused by Sclerotinia homoeocarpa in Turfgrass of Golf Course (Sclerotinia homoeocarpa에 의한 잔디동전마름병(Dollar spot)의 약제 저항성균 발생 및 방제)

  • 심규열;민규영;신현동;이현주
    • Asian Journal of Turfgrass Science
    • /
    • v.15 no.1
    • /
    • pp.1-8
    • /
    • 2001
  • Antifungal activity of 20 chemicals registered to turfgrass diseases was evaluated. Among the chemicals, iprodione, benomyl, iprodione+thiram, pencycuron+tebuconazole, hexaconazole, and iprodione+thiophanate-methyl exhibited high antifungal activity to the dollar spot fungus. All isolates were greatly inhibited by the chemicals at the concentration over 32ppm($\mu\textrm{g}$/ml). However, sensitivity of the isolates to chemicals was varied at the lower concentration as 8 and 16 ppm as follows. The isolate originated from Ora golf course was resistant to iprodione and iprodione+thiophanate methyl, Gonjiam isolate to iprodion, Youngpyung isolate to iprodione+thiram, and Dogo isolate to iprodione+thiram, pencycuron+tebuconazole, and tebuconazole. It was found from this study that the varied chemical resistance among the isolates was positively related to the application time of the chemical in the golf course. Consequently, when a chemical was applied more often times than the others to the golf course, the fungal isolates originate from the field showed higher resistance to the former chemical. Effects of the chemicals on control of the dollar spot was evaluated in the field. All tested chemicals revealed over 70% disease control efficacy, however, mepronil+propiconazole was the best showing 83% control efficacy and followed by fenarimo, iprodione, terbuconazole, thiram, and thiophanate-methyl.

  • PDF

A Study of the Giving and Receiving Verbs in TOUSEISYOUSEIKATAGI (『当世書生気質』에 나타난 수수동사에 관한 고찰 - 'やる·あげる·さしあげる'와 'くれる·くださる'를 중심으로)

  • Yang, Jung Soon
    • Cross-Cultural Studies
    • /
    • v.19
    • /
    • pp.271-293
    • /
    • 2010
  • Japanese Give and Receive Verbs are divided into "YARU", "MORAU" and "KURERU". These are influenced by the subject, speaker's viewpoint and meaning. Three verbs are used in a different way depending on who is the giver and who is the taker. I analyze "YARU" and "KURERU" Verbs used in TOUSEISYOUSEIKATAGI. It focus on politeness, gender, and meaning when combined with 'TE'. As an expression of politeness, 'Yaru' is to give to a person of lower social status or an animal or plant. 'Ageru' is to give to an equal ora person of lower social status nowadays. However, 'Ageru' which is treated as elegance of the language remained expression of respect, 'Yaru' is used when the receiver is a person of lower social status and equal social status in TOUSEISYOUSEIKATAGI. 'Kureru' is used when the receiver is a person of lower social status and equal social status, 'kudasaru' is used when a person of higher social status gives the speaker something in TOUSEISYOUSEIKATAGI. Women speakers use 'oyarinasai' 'oyariyo' 'ageru' 'okureru' and men speakers use 'yaru' 'kureru'. Speech patterns peculiar to men are 'kuretamae' 'kurenka'. If the verbs are joined to "TE", they obtain abstract meaning as well as a movement of things. They express some modality for action of the preceeding verbs. The modality has the following meanings ; good will, goodness, benefits, kindness, hopeness, expectation, disadvantage, injury, ill will and sarcasm. In addition, 'TE YARU' expresses the speaker's strong will, 'TE KURERU' expresses the speaker's request.

Suggestions for Increasing Utilization of KORA for Supporting the Off-site Risk Assessment System (화학사고 장외영향평가 지원 프로그램(KORA)의 활용도 증대를 위한 제언)

  • Kim, Jungkon;Ryu, Jisung;Ryu, Taekwon;Kwak, Sollim;Lim, Hyeongjun;Choi, Woosoo;Jung, Jinhee;Lee, Jieun;Lim, Dongyeon;Yoon, Junheon
    • Journal of Environmental Health Sciences
    • /
    • v.44 no.2
    • /
    • pp.124-132
    • /
    • 2018
  • Objectives: All enterprises intending to install and operate hazardous chemical handling facilities should prepare an off-site risk assessment (ORA) report that evaluates the impact of potential chemical accidents on the surrounding environment and population. This study was conducted to introduce the process of development and the functioning of the Korea Off-site Risk Assessment support tool (KORA) developed by the National Institute of Chemical Safety and to suggest manners to increase its utilization. Additionally, this article provided an overview of KORA. Methods: In order to identify problems with and refinements for KORA, the required items for each phase of KORA were derived by analyzing the Chemical Control Act and related administrative regulations. Results: The functions of KORA made receptor-considered assessment of chemical accidents possible, but several limitations were found in particular phases, such as the analysis of impact range, consideration of sensitive receptors, and assessment of environmental receptors. Conclusion: In this study, we suggested manners to increase the utilization of KORA. It is anticipated that the further research suggested in the study could contribute to the stabilization of the KORA system.

The antiproliferative activity of cannabidiol ethyl ethers against human ora epitheloid carcinoma cells

  • Baek, Seung-Hwa;Kang, Kil-Ung;Chung, Soon-Ryang;Kim, Hyung-Min;Chung, Woo-Young;Han, Du-Seok
    • Advances in Traditional Medicine
    • /
    • v.1 no.1
    • /
    • pp.45-54
    • /
    • 2000
  • Cannabidiol derivatives (1, 2 and 3), and 5-fluorouracil (4, 5-FU) were tested for their growth inhibitory effects against human oral epitheloid carcinoma cell lines (KB) using two different 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay and sulforhodamine B protein (SRB) assay. These compounds showed a potent inhibitory activity in vitro in the micromolar range against KB cell lines. In general, the antitumor activity of these compounds (1, 2, 3 and 4) was in a dose-dependent over the micromolar concentration ranges from $1\;{\mu}M\;to\;100\;{\mu}M$. The comparison of $IC_{50}$ values of these compounds in tumor cell lines shows that their susceptibility to these compounds decreases in the following order: CBD > 5-FU > CBDME > CBDDE by the MTT assay and SRB assay. Cannabidiol derivatives (1, 2 and 3), and 5-FU were tested for their cytotoxic effects on NIH 3T3 fibroblasts using two different MTT assay and SRB assay. These compounds exhibited potent cytotoxic activities in vitro in the micromolar range against NIH 3T3 fibroblasts. In general, the cytotoxic activities of these compounds (1, 2, 3 and 4) were in a dose-dependent over the micromolar concentration range $1\;{\mu}M\;to\;100\;{\mu}M$. The comparison of $CD_{50}$ values of these compounds on NIH 3T3 fibroblasts shows that their susceptibility to these compounds decreases in the following order; CBD > 5-FU > CBDDE > CBDME by MTT assay, CBD > 5-FU > CBDME > CBDDE by SRB assay. These results suggest that cannabidiol (1, CBD) retains the most growth-inhibitory activity against KB cell lines.

  • PDF