• Journal of Yeungnam Medical Science
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• 제39권1호
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• pp.3-11
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• 2022

Lymphoma is the most common primary tumor of the orbit, accounting for 55% of all orbital malignancies. When divided into histopathological subtypes, extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) comprises the largest proportion. Clinical manifestations are unspecific, but in patients with slow-growing painless orbital mass, or red conjunctival lesion suggestive of 'salmon patch', ocular adnexa lymphoma (OAL) should be suspected. Although the pathogenetic mechanism of ocular adnexal MALT lymphoma (OAML) is not yet fully understood, the relationship between OAML and Chlamydia psittaci has been hypothesized recently, similar to that between gastric MALT lymphoma and Helicobacter pylori. This suggests a new treatment option for OAML; bacterial eradication therapy with systemic antibiotics. Several other treatment methods for OAML have been introduced, but no treatment guidelines have been established yet. In this article, we summarize the current knowledge on the clinical features, pathogenesis, diagnostic methods, therapeutic strategies, and prognosis of OAML.

• Journal of Pharmaceutical Investigation
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• 제2권1호
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• pp.5-13
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• 1972

There are some repels in which they studied on the change of acid-consuming capacity of aluminium hydroxide resulted from the passing of time. However, the relationship between grain sizes(particle sizes) and the acid-consuming capacity of dried aluminium hydroxide gel was not been studied. And studies on the grain sizes of aluminium hydroxide gel qualified by pharmacopoeia of Korea has not been reported. For the purpose of studying these two problems, the author prepared two-kinds of aluminium hydroxide gel as follows : $Na_2OAl_2O_3+CO_2------{\longrightarrow}Al(OH)_3{\cdots}{\cdots}{\cdots}$sample 1 $Al_2(SO_4)_318H_2O+6NaHCO_3{\longrightarrow}Al(OH)_3{\cdots}{\cdots}{\cdots}$sample 2 Both of sample 1 and 2 are found to be amorphous by X-ray diffraction methods, and their acid-consuming capacities were determined by the method of pharmacopeia of Korea. The grain size was measured by X-ray diffraction method, the particle sizes observed by electron microscopy, and the change of acid-consuming capacity with passing of time was determined by the method of pharmacopoeia of Korea. The results of these studies are summerized as follows: 1. The grain size was linearly enlarged as the time goes by. The aluminium hydroxide gel gradually crystallized in a certain period of time. 2. The acid-consuming capacity was in exponential function, decreased as the grain size of them enlarged. 3. One particle consists of tens of grains.4. Grinding the Sample obtained in any period of testing time in mortar did not change both their grain size and their acid-consuming capacity. 5. The grain size of dried aluminium hydroxide gel ought to be micronized less than $100{\AA}$ for maintaining the ability such as consumes 250m1 of 0. 1N-HC1 solution per Is of $Al(OH)_3$ described in pharmacopoeia of Korea.

• 에너지공학
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• 제22권1호
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• pp.17-27
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• 2013

국내 전력시장은 포화상태로 해외시장 개척을 통해 국내 전력산업의 한계를 극복하기 위한 방안을 모색하려 한다. 해외 전력시장에서 우리나라의 전력산업이 경쟁력을 갖추고 지속적인 성장을 추구하기 위해서 해외시장에 적극적인 투자를 추진하고 있다. 이에 본 논문에서는 여러 전력산업에서 가장 대표적인 화력발전 중 석탄화력발전의 해외수출이 국내 경제에 미치는 파급효과를 분석하고자 한다. 특히 경제적 파급효과로 생산유발효과, 부가가치 유발효과, 취업유발효과의 3가지를 분석하되, 수요유도형 모형을 적용한 분석 결과를 제시한다. 한국은행 산업연관표 통합소분류 기준 168부문 중에서 17개부문을 석탄화력발전 관련 부문이라 정의한 후, 석탄화력발전 관련 산업을 중심에 놓고 이를 외생화하여 분석한다. 과거 석탄화력발전 수출 사례를 적용하여 석탄화력발전 해외수출의 경제적 파급효과를 분석한다. 석탄화력발전 해외수출의 생산유발효과, 부가가치 유발효과, 취업유발효과는 각각 28,525억원, 9,725억원, 14,761명으로 분석되었다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권8호
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• pp.3727-3731
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• 2016

Background: The most common type of ocular lymphoma is non-Hodgkin lymphoma (NHL), categorized into two groups: indolent (slow growing) and aggressive (rapid growing). Differentiating benign reactive lymphoid hyperplasia (RLH) from malignant ocular adnexal lymphoma (OAL) is challenging. Histopathology, immunohistochemistry (IHC) and flow cytometry have been used as diagnostic tools in such cases. Materials and Methods: In this retrospective case series, from 2002 to 2013 at Farabi Eye Center, 110 patients with ocular lymphoproliferative disease were enrolled. Prevalence, anatomical locations, mean age at diagnosis and the final diagnosis of the disease with IHC were assessed. Comparison between previous pathologic diagnoses and results of IHC was made. Immunoglobulin light chains and B-cell and T-cell markers and other immuno-phenotyping markers including CD20, CD3, CD5, CD23, CD10, CYCLIND1 and BCL2 were evaluated to determine the most accurate diagnosis. The lymphomas were categorized based on revised European-American lymphoma (REAL) classification. Results: Mean age ${\pm}$ SD (years) of the patients was $55.6{\pm}19.3$ and 61% were male. Patients with follicular lymphoma, large B-cell lymphoma or chronic lymphocytic leukemia/small cell lymphoma (CLL/SLL) tended to be older. Nine patients with previous diagnoses of low grade B-cell lymphoma were re-evaluated by IHC and the new diagnoses were as follows: extranodal marginal zone lymphoma(EMZL) (n=1), SLL(n=1), mantle cell lymphoma (MCL) (n=3), reactive lymphoid hyperplasia RLH (n=2). Two cases were excluded due to poor blocks. Flow cytometry reports in these seven patients revealed SLL with positive CD5 and CD23, MCLwith positive CD5 and CyclinD1 and negative CD23, EMZL with negative CD5,CD23 and CD10. One RLH patient was negative for Kappa/Lambda and positive for CD3 and CD20 and the other was positive for all of the light chains, CD3 and CD20. Orbit (49.1%), conjunctiva (16.1%) and lacrimal glands (16.1%) were the most common sites of involvement. Conclusions: Accurate pathological classification of lesions is crucial to determine proper therapeutic approaches. This can be achieved through precise histologic and IHC analyses by expert pathologists.

• 한국안광학회지
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• 제13권2호
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• pp.23-28
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• 2008

목적: 1064 nm용 2.0~8.0X 줌 빔 확대기의 개발. 방법: 3군 줌 궤적에 대한 초기 설계 값을 신속하게 확보할 수 있는 프로그램을 개발하고, 이 프로그램과 Sigma 2000 상용프로그램을 활용하여 줌 빔 확대기를 설계 개발한다. 결과: 3군 줌 궤적에 대한 초기 설계 값을 신속하게 확보할 수 있는 프로그램을 개발하여, 이 프로그램과 상용프로그램 Sigma 2000을 활용하여 2배에서 8배까지 줌이 가능한 1064 nm용 줌 빔 확대기를 설계 개발하였다. 개발된 줌 빔 확대기는 입사측 유효경이 8 mm이고 출사측 유효경이 32 mm이며 유한광선 수차량이 0.0001 rad 이내인 성 능을 갖게 되었다. 전체 시스템의 렌즈 총 길이가 125 mm에서 135 mm 사이가 되도록 제한하였기 때문에 줌 구동의 변화로 인한 전체 경통의 길이 변화는 10 mm 이내로 되었다. 결론: 3군 줌 궤적에 대한 초기 설계 값을 신속하게 확보할 수 있는 프로그램을 개발하여 2배에서 8배까지 줌이 가능한 1064 nm용 줌 빔 확대기를 설계 개발하였다.