• Journal of Korean Medical classics
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• v.19 no.1 s.32
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• pp.168-193
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• 2006

${\ulcorner}$Sanghanlonju Taeyangpyun(傷寒論注 太陽篇)${\lrcorner}$ is a part of ${\ulcorner}$Uijonggumgam(醫宗金鑑)${\lrcorner}$, ${\ulcorner}$Ui jong gum gam${\lrcorner}$ is a voluminous medical book. That was complied by O gyum(吳謙) who was a chief of Taeuiwon(太醫院). In this paper, I speculated O gyum's annotations and compared other annotations in some parts, needed a comparing. O gyum's academic features, appeared in ${\ulcorner}$Sanghanlon ju Taeyangpyun${\lrcorner}$ are as follow. O gyum understood the Taeyang(太陽) as a meaning of Gyounglak(經絡), and explained that the Taeyang part disease arose from a pathologic course of Banggwanggyong(膀胱經). He maintained The Samgangjeonglip(三綱鼎立) theory and restructrured the text order in his own way. He fixed the contents of ${\ulcorner}$Sanghanlon(傷寒論)${\lrcorner}$ to accommodate his medical view. And then he compared and distinguished similar diseases or prescriptions necessary to division clinically. And then about issues of long standing in study of San han lon, he showed his own opinions. Finally, remarking many other commentator's theory, he tried to understand Taeyangpyun(太陽篇).

• Proceedings of the Korean Magnestics Society Conference
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• 1993.11a
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• pp.38-39
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• 1993

• Journal of Microbiology and Biotechnology
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• v.34 no.3
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• pp.606-621
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• 2024

This study evaluated the hepatoprotective effect of fermented Protaetia brevitarsis larvae (FPB) in ethanol-induced liver injury mice. As a result of amino acids in FPB, 18 types of amino acids including essential amino acids were identified. In the results of in vitro tests, FPB increased alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) activities. In addition, FPB treatment increased cell viability on ethanol- and H₂O₂-induced HepG2 cells. FPB ameliorated serum biomarkers related to hepatoxicity including glutamic oxaloacetic transaminase, glutamine pyruvic transaminase, total bilirubin, and lactate dehydrogenase and lipid metabolism including triglyceride, total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol. Also, FPB controlled ethanol metabolism enzymes by regulating the protein expression levels of ADH, ALDH, and cytochrome P450 2E1 in liver tissue. FPB protected hepatic oxidative stress by improving malondialdehyde content, reduced glutathione, and superoxide dismutase levels. In addition, FPB reversed mitochondrial dysfunction by regulating reactive oxygen species production, mitochondrial membrane potential, and ATP levels. FPB protected ethanol-induced apoptosis, fatty liver, and hepatic inflammation through p-AMP-activated protein kinase and TLR-4/NF-κB signaling pathways. Furthermore, FPB prevented hepatic fibrosis by decreasing TGF-β1/Smad pathway. In summary, these results suggest that FPB might be a potential prophylactic agent for the treatment of alcoholic liver disease via preventing liver injury such as fatty liver, hepatic inflammation due to chronic ethanol-induced oxidative stress.

• Journal of dental hygiene science
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• v.15 no.1
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• pp.24-31
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• 2015

This research was conducted in order to examine the effect of tooth brushing room M elementary school in Changwon-city and to provide foundation data for effective project operation afterwards. The subjects were 347 students at the M elementary school where the tooth brushing room was being taught. The control group is 289 students at J elementary school where the tooth brushing room was not being taught. Research and analysis were carried out with structured survey and examination of decayed, missing, filled teeth (DMFT) index, decayed, missing, filled tooth surface (DMFS) index and O'leary index. The data was analysed by IBM SPSS Statistics ver. 19.0 program and the result is as follows: Depends on the tooth brushing room there was difference in statistical significance in filling teeth, sealant tooth surface, filling tooth surface, missing tooth surface, DMFS, O'leary index between the subject and control group. The less the frequency of brushing, the higher the DMFT index. Negative correlation was statistically significant. With incorrect brushing method, the less the frequency, the higher the DMFS index, Negative correlation was statistically significant. When the tooth brushing room was being implemented, O'leary index became low, negative correlation was statistically significant. As a result, in order to continue the effective operation of tooth brushing room, constant supervision and monitoring on students should be acutely needed by a principal, a school nurse and teachers in charge. Also together with a systemized cooperation between a health center and a nearby university's related majors departments, the research proposes to execute constant oral health education and to expand the implementation project of the tooth brushing room at nearby elementary schools.