• 제목/요약/키워드: O(($^{3}P_{J}$)

검색결과 817건 처리시간 0.03초

수종의 암세포주에 대한 인삼 사포닌 및 그 분해산물의 구조와 세포독성 관계 (CYTOTOXICITIES OF GINSENG SAPONINS AND THEIR DEGRADATION PRODUCTS AGAINST SOME CANCER CELL LINES AND STRUCTURE-ACTIVITY RELATIONSHIP)

  • 백남인;김신일;이유희;김동선;박종대;이천배
    • 고려인삼학회:학술대회논문집
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    • 고려인삼학회 1993년도 학술대회지
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    • pp.132-137
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    • 1993
  • 한국산 고려 홍삼을 산 또는 알칼리로 가수분해하여, 여러가지 사포게닌과 프로사포게닌을 제조하였으며, 분광학적 데이터와 물리 데이터 등으로부터 이들의 화학 구조를 결정하였다. 이들 중 몇종의 분해산물은 A549, SK - OV. - 3, P388, L1210, SK - Mel - 2 및 K562 등의 암세포에 대하여 세포 독성을 나타내었다. Diol계와 triol계 모두 20번 탄소의 절대구조만이 다른 입체 이성체간의 세포독성의 차이는 인정되지 않았으며, diol 계의 물질들이 triol계 물질보다는 더 높은 활성을 나타내었다. 일반적으로 결합된 탄소의 수가 적을수록 세포독성은 강하여지는 경향??? 보였다.

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땅콩비닐 일피복재배에 관한 연구 (Studies on the Vinyl-mulching Culture of Peanut)

  • 이기백;나종성;노승표;이돈길
    • 한국작물학회지
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    • 제24권3호
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    • pp.67-74
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    • 1979
  • 땅콩을 온도조건 및 재실거리를 이동시켜 시험한 결과를 요약하면 다음과 같다. 1. 지온은 비닐 무피복구에 비하여 비닐 피복구가 4월중순경에 4.6$^{\circ}C$나 높았으며 초기생육의 왕성으로 햇빛을 차단하므로 6월중순부터는 지온이 떨어졌다. 2. 생육기간중에 착화수는 상당수에 이르나 그중 수정하여 자방병이 생기고 지하에 침입하여 결실하는 것은 58.8%이다. 3. 개화수의 대부분이 1~4지에 착생하나, 자엽정분지는 발육이 개화수의 60~70%를 점육하고 있다. 4. 총개화수는 분지의 차별 착생율에는 심한 차가 인정되었다. 5. 주당협실비율 및 결실비율은 밀식보다 소식에서 높았고 만파보다 조파에서 좋았다. 6. 유효개화 한계기는 7월중순이다. 7. 식물체분석은 경보다 엽이 N, Ca, Mg 함량이 많으나 P_2O$_{5}$, K_2는 엽보다 경에서 많았다. 8. 수량은 무피복 5월 10일(129kg/10a)에 비하여 비닐피복 5월 10일이 9%, 4월 20일이 49% 증수되었다.

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냉혈K+ 심정지약을 사용한 개심술 예에서 심정지시간에 따른 심근보호효과에 관하여 (Clinical Observations on Myocardial Protection with Cold Blood Potassium Cardioplegia According to the Duration of Ischemic Arrest)

  • 정정기;이동준
    • Journal of Chest Surgery
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    • 제24권7호
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    • pp.647-655
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    • 1991
  • The efficacy of cold blood potassium cardioplegia during periods of ischemic arrest was assessed in 88 patients undergoing open heart surgical procedures at Chonnam National University Medical School from December, 1987 to January, 1989. The purpose of this study was to determine if the aortic cross clamping time[ACCT] over 120 minutes correlated with operative mortality, incidence of postoperative ventricular tachyarrhythmias, needs of postoperative inotropic support and serum enzyme levels. The patients were divided according to aortic cross clamping time[less than 120 minutes and 120 minutes or greater]. The results were as follows: 1. The operative mortality was 3.2% in ACCT<120min group and 7.7% in ACCT>120 min group. 2. The incidence of postoperative ventricular tachyarrhythmia was 1.6% in ACCT <120min group and 11.5% in ACCT>120min group[p<0.05]. 3. The incidence of postoperative inotropic support in congenital heart disease was 13.0Fo in ACCT<120min group and 45.0%o in ACCT>120min group[p<0.05]. The incidence in acquired heart disease was 26.0% in ACCT<120min group and 40.0% in ACCT> 120min group. 4. After cardiopulmonary bypass, serum GOT, LDH, CPK and CPK - MB were elevated prominently. Children showed higher value of the enzymes examined than adults did before and after cardiopulmonary bypass. In congenital heart diseases, postoperative serum GOT, LDH, CPK and CPK - MB levels of ACCT>120min group were significantly higher than those of ACCT<120min group. Postoperative serum GOT, LDH and CPK - MB levels of ACCT>=120min group were significantly higher than those of ACCT<120min group also in acquired heart diseases. The results suggest that the myocardial protective effect with cold blood potassium cardioplegic solutions was not sufficient when the aortic cross clamping time was over 120 minutes.

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밤의 Polyethylene Film 밀봉 저장 효과 (Studies on storing Chest - nut(Castanea crenata var. dulcis Nakai) Sealing with Polyethylene Film)

  • 이병영;윤인화;김영배;한판주;이정명
    • 한국식품과학회지
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    • 제17권5호
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    • pp.331-335
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    • 1985
  • 밤의 안전저장 방법을 개발하고자 충남 공주산 옥광밤을 공시품종으로 하여 호흡량 조사 및 P.E 필름 두께별 저장시험을 실시하였던 바 수확후 호흡량은 온도가 상승함에 따라 증가하여 $20^{\circ}C$에서 수확 3일후에 35$CO_2$mg/kg/hr이었으며, 호흡량의 온도계수 $Q_{10}$은 2.4$\sim$2.7이었다. 그러고 방을 상온에서는 0.03mm 저온에서는 0.05mm P.E 필름으로 밀봉저장하는 것이 포장내의 가스농도가 C.A 저장의 적정가스농도에 접근하는 탄산가스 $5{\sim}6%$, 산소 3% 정도로 유지되어 감모율을 $8{\sim}15%$로 억제한 상태에서 $7{\sim}9$개월간 저장 가능하였으며 저장기간이 길어짐에 따라 수용성탄닌은 감소하고 환원당이 증가하여 식미가 향상되었다.

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Effects of air-abrasion pressure on the resin bond strength to zirconia: a combined cyclic loading and thermocycling aging study

  • Al-Shehri, Eman Z.;Al-Zain, Afnan O.;Sabrah, Alaa H.;Al-Angari, Sarah S.;Dehailan, Laila Al;Eckert, George J.;Ozcan, Mutlu;Platt, Jeffrey A.;Bottino, Marco C.
    • Restorative Dentistry and Endodontics
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    • 제42권3호
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    • pp.206-215
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    • 2017
  • Objectives: To determine the combined effect of fatigue cyclic loading and thermocycling (CLTC) on the shear bond strength (SBS) of a resin cement to zirconia surfaces that were previously air-abraded with aluminum oxide ($Al_2O_3$) particles at different pressures. Materials and Methods: Seventy-two cuboid zirconia specimens were prepared and randomly assigned to 3 groups according to the air-abrasion pressures (1, 2, and 2.8 bar), and each group was further divided into 2 groups depending on aging parameters (n = 12). Panavia F 2.0 was placed on pre-conditioned zirconia surfaces, and SBS testing was performed either after 24 hours or 10,000 fatigue cycles (cyclic loading) and 5,000 thermocycles. Non-contact profilometry was used to measure surface roughness. Failure modes were evaluated under optical and scanning electron microscopy. The data were analyzed using 2-way analysis of variance and ${\chi}^2$ tests (${\alpha}=0.05$). Results: The 2.8 bar group showed significantly higher surface roughness compared to the 1 bar group (p < 0.05). The interaction between pressure and time/cycling was not significant on SBS, and pressure did not have a significant effect either. SBS was significantly higher (p = 0.006) for 24 hours storage compared to CLTC. The 2 bar-CLTC group presented significantly higher percentage of pre-test failure during fatigue compared to the other groups. Mixed-failure mode was more frequent than adhesive failure. Conclusions: CLTC significantly decreased the SBS values regardless of the air-abrasion pressure used.

$\beta$-Galactosidase의 Tannin 활성화 섬유소 입자에의 고정화 (Immobilization of $\beta$-Galactosidase from E. coli K-12 CHS36 Using Tannin - Activated Cellulose Beads)

  • 홍영수;권석태;전문진;엠써네쓰
    • Applied Biological Chemistry
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    • 제26권4호
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    • pp.217-221
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    • 1983
  • Tannin 및 p-benzoquinone으로 활성화시킨 다공성 섬유소 입자를 사용하여 대장균 변이주(E. coli K-12 CSH36)로부터 추출한 $\beta$-galactosidase를 고정화시켜 효소학적 성질과 그 응용성에 대하여 연구하였다. $\beta$-galactosidase는 pH 11.0으로 맞춘 tannin과 p-benzoquinone을 사용하여 6시간 동안 활성화시킨 섬유소 입자담체에 고정화 시켰을 때 그 잔여 활성도가 가장 높았다. $\beta$-galactosidase의 최적작용 pH는 5.5였으나 고정화 시켰을 때 pH 6.0으로 변화하였으며 최적작용 온도는 고정화 전이나 후에도 일정하였다. $\beta$-galactosidase의 Km 값은 $4.0{\times}10^(-4)M$으로 나타났으며 고정화 효소의 경우에는 $7.5{\times}10^(-4)M$이었다. 고정화 효소의 재사용성을 검토한 결과, 담체 활성화 물질로 tannin과 p-benzoquinone 용액을 사용하였을 때 20히 사용 후에 초기 효소 활성도의 80% 이상이 유지되는 결과를 나타내었다.

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모세관 전기영동 및 전기화학적 검출 시스템을 위한 일회용 마이크로칩 (Microfabricated Disposable Microchip with a Capillary Electrophoresis and Integrated Amperometric Detection)

  • 김주호;강치중;김용상
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2004년도 하계학술대회 논문집 C
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    • pp.2131-2133
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    • 2004
  • 모세관 전기영동 및 전기화학적 검출 시스템을 마이크로 시스템에 적용하여 ITO 유리기판과 polydimethylsiloxane (PDMS)로 제작하였다. 제작된 모세관 전기영동 및 전기화학적 검출 시스템은 일회용으로 사용가능하며 전기화학적 검출에 아주 적합한 특성을 보인다. 모세관 전기영동 및 전기화학적 검출 시스템은 주입과 분리 채널 (80 ${\mu}m$${\sim}$ 40 ${\mu}m$ 깊이)을 가진 PDMS 층과 유리기판 위에 검출 전극으로 사용되는 ITO가 형성된 층으로 구성된다. PDMS 층과 ITO 유리 기판은 UV-$O_3$ cleaner를 사용하여 접합하였다. 완충용액은 10 mM 2-(N-morpholino)ethanesulfonic acid (MES)를 사용하였고 분석물질은 1 mM 농도의 dopamine과 1 mM 농도의 catechol을 사용하였다. 60 V/cm 전계로 주입 및 분리를 하였으며 작업전극과 기준전극 간의 전위는 +600 mV로 유지하며 분석물질의 농도에 비례하는 전류량법으로 측정하였다. 전기화학적 검출 회로는 천기영동 전계의 간섭으로부터 분리하였다. 10 mM MES 완충용액에서 바탕 전류의 크기가 ${\sim}$10 pA 일 때 측정전류 값은 10 nA이다. 측정된 피크 값은 기존의 Au 전극과 비교하여 선택성, 감도, 분해능이 유사한 특성을 보여준다.

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원자력 발전소 제품 데이터의 공유를 위한 중립 모델 기반의 데이터 웨어하우스의 구축 (A Standard Way of Constructing a Data Warehouse based on a Neutral Model for Sharing Product Dat of Nuclear Power Plants)

  • 문두환;천상욱;최영준;한순흥
    • 한국CDE학회논문집
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    • 제12권1호
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    • pp.74-85
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    • 2007
  • During the lifecycle of a nuclear power plant many organizations are involved in KOREA. Korea Plant Engineering Co. (KOPEC) participates in the design stage, Korea Hydraulic and Nuclear Power (KHNP) operates and manages all nuclear power plants in KOREA, Dusan Heavy Industries manufactures the main equipment, and a construction company constructs the plant. Even though each organization has a digital data management system inside and obtains a certain level of automation, data sharing among organizations is poor. KHNP gets drawing and technical specifications from KOPEC in the form of paper. It results in manual re-work of definition and there are potential errors in the process. A data warehouse based on a neutral model has been constructed in order to make an information bridge between design and O&M phases. GPM(generic product model), a data model from Hitachi, Japan is addressed and extended in this study. GPM has a similar architecture with ISO 15926 "life cycle data for process plant". The extension is oriented to nuclear power plants. This paper introduces some of implementation results: 1) 2D piping and instrument diagram (P&ID) and 3D CAD model exchanges and their visualization; 2) Interface between GPM-based data warehouse and KHNP ERP system.

한국 한자음의 빈도 관련 정보 및 음절 구조 제약 (Frequency Related Information and Syllable Structure Constraints on Sino-Korean)

  • 신지영
    • 말소리와 음성과학
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    • 제1권2호
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    • pp.129-140
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    • 2009
  • The purpose of the present study is to investigate frequency related information and syllable structure constraints on Sino-Korean. Previous studies on Sino-Korean have mostly investigated the historical change of sounds and reviewed archaic features of Chinese language in Sino-Korean. Unfortunately, there is little study on the sounds of contemporary Sino-Korean in terms of syllable structure constraints. For the purpose of the present study, sounds of 7,742 Chinese characters used in Sino-Korean (7,795 syllables) were investigated and syllable matrices made based on the results of frequency related information. As a result, 483 syllable types were observed and the most frequently observed syllables were as follows: /ku/ (103) > /ki/ (100) > /ju/ (87) > /pi/ (86). Only 16 out of 19 consonants are used for Sino-Korean. /$t^{\ast}$/ and /$p^{\ast}$/ are never used in Sino-Korean and /kh, $s^{\ast}$, $k^{\ast}$/ occur only a few times (3, 2, 1 respectively). /k/ (17.5%) shows the highest frequency and /n, ${\eta}$, 1, tc, m/ occupied the next rankings. Among 20 vowel types, /a/ showed the highest frequency and /o, u, i, $j{\Lambda}$, ${\Lambda}$/ occupied the next rankings. Based on the syllable matrices, gaps were observed and classified into accidental or systematic ones. Onset and nucleus, nucleus and coda, onset and coda, and other syllable structure constraints of Sino-Korean were listed.

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기-액(氣-液) 2상유동(二相流動)시 항력(抗力)에 관(關)한 연구(硏究) (The Study on the Drag Reduction for Gas/Liquid Two Phase Flow)

  • 차경옥;오율권;김재근
    • 한국분무공학회지
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    • 제1권3호
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    • pp.20-28
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    • 1996
  • It is well known that drag reduction in single phase liquid flow is affected by polymer material, molecular weight, polymer concentration, pipe diameter, and flow velocity. Drag reduction in two phase flow can be applied to the transport of crude oil, phase change system such as chemical reactor, pool and boiling flow, and to present cavitation which occurs in pump impellers. But the research of drag reduction in two phase flow is not sufficient. The purpose of the present work is to evaluate the drag reduction by measuring pressure drop, void fraction whether polymer is added in the horizontal two phase system or not. Experiment has been conducted in a test section with 24 m of the inner diameter and 1,500 mm of the length. The used polymer materials are two kinds of polyacrylamide[PAAM] and co-polymer[A611P]. The polymer concentration was varied with 50, 100 and 200 ppm under the same experimental conditions. Experimental results were shown that the drag is higher reduced by co-polymer rather than polyanylamide.

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