• Title/Summary/Keyword: O(($^{3}P_{J}$)

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CYTOTOXICITIES OF GINSENG SAPONINS AND THEIR DEGRADATION PRODUCTS AGAINST SOME CANCER CELL LINES AND STRUCTURE-ACTIVITY RELATIONSHIP (수종의 암세포주에 대한 인삼 사포닌 및 그 분해산물의 구조와 세포독성 관계)

  • Baek N.I.;Kim S.I.;Lee Y.H.;Kim D.S.;Park J.D.;Lee C.B.
    • Proceedings of the Ginseng society Conference
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    • 1993.09a
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    • pp.132-137
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    • 1993
  • Several Prosapogenins and sapogenins obtained by acid hydrolysis or alkaline cleavage of Korean red ginseng saponins were separated and identified by spectral and physical methods. Some of these degradation products showed the cytotoxic activities against various cancer cell lines, that is, A549, SK - OV - 3, L121O, P388 and K562. The significant difference of activity between stereoisooers was not approved and the activity was inversely proportional to the number of sugars binding to sapogenins. It was clear that diol type prosapogenins and sapogenins were more cytotoxic than triol type ones.

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Studies on the Vinyl-mulching Culture of Peanut (땅콩비닐 일피복재배에 관한 연구)

  • Lee, G.B.;La, J.S.;Nho, S.P.;Lee, D.G.
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.24 no.3
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    • pp.67-74
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    • 1979
  • Peanut was cultured with varying planting density and sowing date with and without vinyl-film mulching. Vinyl-film mulching raised soil temperature 4.6$^{\circ}C$ higher than the non-mulched during April and early May, but later-on the soil temperature was similar between the two treatments. The ripening and slender grain ratio increased with closer spacing and earlier sowing. Compared with ordinary cultural practices of May 10th sowing without mulching the peanut yield increased by 9% by mulching sown May 10th, and by 49% by mulching and early sowing April 20th.

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Clinical Observations on Myocardial Protection with Cold Blood Potassium Cardioplegia According to the Duration of Ischemic Arrest (냉혈K+ 심정지약을 사용한 개심술 예에서 심정지시간에 따른 심근보호효과에 관하여)

  • Jeong, J.G.;Lee, D.H.
    • Journal of Chest Surgery
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    • v.24 no.7
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    • pp.647-655
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    • 1991
  • The efficacy of cold blood potassium cardioplegia during periods of ischemic arrest was assessed in 88 patients undergoing open heart surgical procedures at Chonnam National University Medical School from December, 1987 to January, 1989. The purpose of this study was to determine if the aortic cross clamping time[ACCT] over 120 minutes correlated with operative mortality, incidence of postoperative ventricular tachyarrhythmias, needs of postoperative inotropic support and serum enzyme levels. The patients were divided according to aortic cross clamping time[less than 120 minutes and 120 minutes or greater]. The results were as follows: 1. The operative mortality was 3.2% in ACCT<120min group and 7.7% in ACCT>120 min group. 2. The incidence of postoperative ventricular tachyarrhythmia was 1.6% in ACCT <120min group and 11.5% in ACCT>120min group[p<0.05]. 3. The incidence of postoperative inotropic support in congenital heart disease was 13.0Fo in ACCT<120min group and 45.0%o in ACCT>120min group[p<0.05]. The incidence in acquired heart disease was 26.0% in ACCT<120min group and 40.0% in ACCT> 120min group. 4. After cardiopulmonary bypass, serum GOT, LDH, CPK and CPK - MB were elevated prominently. Children showed higher value of the enzymes examined than adults did before and after cardiopulmonary bypass. In congenital heart diseases, postoperative serum GOT, LDH, CPK and CPK - MB levels of ACCT>120min group were significantly higher than those of ACCT<120min group. Postoperative serum GOT, LDH and CPK - MB levels of ACCT>=120min group were significantly higher than those of ACCT<120min group also in acquired heart diseases. The results suggest that the myocardial protective effect with cold blood potassium cardioplegic solutions was not sufficient when the aortic cross clamping time was over 120 minutes.

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Studies on storing Chest - nut(Castanea crenata var. dulcis Nakai) Sealing with Polyethylene Film (밤의 Polyethylene Film 밀봉 저장 효과)

  • Lee, B.Y.;Yoon, I.H.;Kim, Y.B.;Han, P.J.;Lee, Ch.M.
    • Korean Journal of Food Science and Technology
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    • v.17 no.5
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    • pp.331-335
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    • 1985
  • Series of study were conducted to develop a method for longterm storage of chest-nut with preserving it's taste and freshness. Experiments were carried out with Korean chest-nut (Castanea crenata var. Okkwang) sealed in polyethylene (P.E) film stored under the ambient and low temperature. Summarized results are as follow: After the harvest, $CO_2$ produced by chest-nut at the early storage was increased with temperature increase. Q10 mg/kg/day, the temperature index of $CO_2$production, by chest-nut ranged 2.4-2.7. It was available to store chest-nut in good condition with 8-15% total loss upto the following may at the ambient temperature sealed in 0.03 mm P.E. film, and upto the following july at the low temperature if sealed in 0.03 or 0.05 mm P.E. film. Throughout the period from one month after the innitiation upto the end of the storage, the rate of $CO_2$and $O_2$ was maintained near the optimum condition for the CA storage of chest-nut. The taste of chest-nut was improved during the storage due to increased reducing-sugar and decreased wate soluble tannin. However, the taste become bitter and unacceptable from the early stage of the storage when used the thicker P.E. film (than above mentioned) for the sealing.

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Effects of air-abrasion pressure on the resin bond strength to zirconia: a combined cyclic loading and thermocycling aging study

  • Al-Shehri, Eman Z.;Al-Zain, Afnan O.;Sabrah, Alaa H.;Al-Angari, Sarah S.;Dehailan, Laila Al;Eckert, George J.;Ozcan, Mutlu;Platt, Jeffrey A.;Bottino, Marco C.
    • Restorative Dentistry and Endodontics
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    • v.42 no.3
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    • pp.206-215
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    • 2017
  • Objectives: To determine the combined effect of fatigue cyclic loading and thermocycling (CLTC) on the shear bond strength (SBS) of a resin cement to zirconia surfaces that were previously air-abraded with aluminum oxide ($Al_2O_3$) particles at different pressures. Materials and Methods: Seventy-two cuboid zirconia specimens were prepared and randomly assigned to 3 groups according to the air-abrasion pressures (1, 2, and 2.8 bar), and each group was further divided into 2 groups depending on aging parameters (n = 12). Panavia F 2.0 was placed on pre-conditioned zirconia surfaces, and SBS testing was performed either after 24 hours or 10,000 fatigue cycles (cyclic loading) and 5,000 thermocycles. Non-contact profilometry was used to measure surface roughness. Failure modes were evaluated under optical and scanning electron microscopy. The data were analyzed using 2-way analysis of variance and ${\chi}^2$ tests (${\alpha}=0.05$). Results: The 2.8 bar group showed significantly higher surface roughness compared to the 1 bar group (p < 0.05). The interaction between pressure and time/cycling was not significant on SBS, and pressure did not have a significant effect either. SBS was significantly higher (p = 0.006) for 24 hours storage compared to CLTC. The 2 bar-CLTC group presented significantly higher percentage of pre-test failure during fatigue compared to the other groups. Mixed-failure mode was more frequent than adhesive failure. Conclusions: CLTC significantly decreased the SBS values regardless of the air-abrasion pressure used.

Immobilization of $\beta$-Galactosidase from E. coli K-12 CHS36 Using Tannin - Activated Cellulose Beads ($\beta$-Galactosidase의 Tannin 활성화 섬유소 입자에의 고정화)

  • Hong, Y.S.;Kwon, S.T.;Chun, M.J.;Sernetz, M.
    • Applied Biological Chemistry
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    • v.26 no.4
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    • pp.217-221
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    • 1983
  • $\beta$-Galactosidase($\beta$-D-galactoside galactohydrolase, E.C. 3. 2. 1. 23) from E. coli K-12 CSH 36 was immobilized on porous cellulose beads which were previously activated with tannin and p-benzoquinone. Their general properties and applicational possibities were investigated. The most effective, enzyme immobilization was obtained when tannin and p-benzoquinone, pH 11.0, were used together as activation reagents and a period of 6 hours of activation. The optimum pH of $\beta$-galactosidase was 5.5 for free enzyme and 6. 0 for the immobilized enzyme, the optimum temperatures for native and immobilized enzyme were both $50^{\circ}C$. Kms of native $\beta$-galactosidase and immobilized enzyme for ONPG(o-nitrophenyl galactopyranoside) were about $4.0{\times}10^(-4)M$ and $7.5{\times}10^(-4)M$, respectively. In the case of tannin : p-benzoquinone activated cellulose beads, the immobilized enzyme retained over 80% of the initial enzyme activity after 20 runs, which is very promising result far a possible industrial application.

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Microfabricated Disposable Microchip with a Capillary Electrophoresis and Integrated Amperometric Detection (모세관 전기영동 및 전기화학적 검출 시스템을 위한 일회용 마이크로칩)

  • Kim, Ju-Ho;Kang, C.J.;Kim, Yong-Sang
    • Proceedings of the KIEE Conference
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    • 2004.07c
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    • pp.2131-2133
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    • 2004
  • 모세관 전기영동 및 전기화학적 검출 시스템을 마이크로 시스템에 적용하여 ITO 유리기판과 polydimethylsiloxane (PDMS)로 제작하였다. 제작된 모세관 전기영동 및 전기화학적 검출 시스템은 일회용으로 사용가능하며 전기화학적 검출에 아주 적합한 특성을 보인다. 모세관 전기영동 및 전기화학적 검출 시스템은 주입과 분리 채널 (80 ${\mu}m$${\sim}$ 40 ${\mu}m$ 깊이)을 가진 PDMS 층과 유리기판 위에 검출 전극으로 사용되는 ITO가 형성된 층으로 구성된다. PDMS 층과 ITO 유리 기판은 UV-$O_3$ cleaner를 사용하여 접합하였다. 완충용액은 10 mM 2-(N-morpholino)ethanesulfonic acid (MES)를 사용하였고 분석물질은 1 mM 농도의 dopamine과 1 mM 농도의 catechol을 사용하였다. 60 V/cm 전계로 주입 및 분리를 하였으며 작업전극과 기준전극 간의 전위는 +600 mV로 유지하며 분석물질의 농도에 비례하는 전류량법으로 측정하였다. 전기화학적 검출 회로는 천기영동 전계의 간섭으로부터 분리하였다. 10 mM MES 완충용액에서 바탕 전류의 크기가 ${\sim}$10 pA 일 때 측정전류 값은 10 nA이다. 측정된 피크 값은 기존의 Au 전극과 비교하여 선택성, 감도, 분해능이 유사한 특성을 보여준다.

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A Standard Way of Constructing a Data Warehouse based on a Neutral Model for Sharing Product Dat of Nuclear Power Plants (원자력 발전소 제품 데이터의 공유를 위한 중립 모델 기반의 데이터 웨어하우스의 구축)

  • Mun, D.H.;Cheon, S.U.;Choi, Y.J.;Han, S.H.
    • Korean Journal of Computational Design and Engineering
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    • v.12 no.1
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    • pp.74-85
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    • 2007
  • During the lifecycle of a nuclear power plant many organizations are involved in KOREA. Korea Plant Engineering Co. (KOPEC) participates in the design stage, Korea Hydraulic and Nuclear Power (KHNP) operates and manages all nuclear power plants in KOREA, Dusan Heavy Industries manufactures the main equipment, and a construction company constructs the plant. Even though each organization has a digital data management system inside and obtains a certain level of automation, data sharing among organizations is poor. KHNP gets drawing and technical specifications from KOPEC in the form of paper. It results in manual re-work of definition and there are potential errors in the process. A data warehouse based on a neutral model has been constructed in order to make an information bridge between design and O&M phases. GPM(generic product model), a data model from Hitachi, Japan is addressed and extended in this study. GPM has a similar architecture with ISO 15926 "life cycle data for process plant". The extension is oriented to nuclear power plants. This paper introduces some of implementation results: 1) 2D piping and instrument diagram (P&ID) and 3D CAD model exchanges and their visualization; 2) Interface between GPM-based data warehouse and KHNP ERP system.

Frequency Related Information and Syllable Structure Constraints on Sino-Korean (한국 한자음의 빈도 관련 정보 및 음절 구조 제약)

  • Shin, Ji-Young
    • Phonetics and Speech Sciences
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    • v.1 no.2
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    • pp.129-140
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    • 2009
  • The purpose of the present study is to investigate frequency related information and syllable structure constraints on Sino-Korean. Previous studies on Sino-Korean have mostly investigated the historical change of sounds and reviewed archaic features of Chinese language in Sino-Korean. Unfortunately, there is little study on the sounds of contemporary Sino-Korean in terms of syllable structure constraints. For the purpose of the present study, sounds of 7,742 Chinese characters used in Sino-Korean (7,795 syllables) were investigated and syllable matrices made based on the results of frequency related information. As a result, 483 syllable types were observed and the most frequently observed syllables were as follows: /ku/ (103) > /ki/ (100) > /ju/ (87) > /pi/ (86). Only 16 out of 19 consonants are used for Sino-Korean. /$t^{\ast}$/ and /$p^{\ast}$/ are never used in Sino-Korean and /kh, $s^{\ast}$, $k^{\ast}$/ occur only a few times (3, 2, 1 respectively). /k/ (17.5%) shows the highest frequency and /n, ${\eta}$, 1, tc, m/ occupied the next rankings. Among 20 vowel types, /a/ showed the highest frequency and /o, u, i, $j{\Lambda}$, ${\Lambda}$/ occupied the next rankings. Based on the syllable matrices, gaps were observed and classified into accidental or systematic ones. Onset and nucleus, nucleus and coda, onset and coda, and other syllable structure constraints of Sino-Korean were listed.

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The Study on the Drag Reduction for Gas/Liquid Two Phase Flow (기-액(氣-液) 2상유동(二相流動)시 항력(抗力)에 관(關)한 연구(硏究))

  • Cha, K.O.;Oh, Y.K.;Kim, J.G.
    • Journal of ILASS-Korea
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    • v.1 no.3
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    • pp.20-28
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    • 1996
  • It is well known that drag reduction in single phase liquid flow is affected by polymer material, molecular weight, polymer concentration, pipe diameter, and flow velocity. Drag reduction in two phase flow can be applied to the transport of crude oil, phase change system such as chemical reactor, pool and boiling flow, and to present cavitation which occurs in pump impellers. But the research of drag reduction in two phase flow is not sufficient. The purpose of the present work is to evaluate the drag reduction by measuring pressure drop, void fraction whether polymer is added in the horizontal two phase system or not. Experiment has been conducted in a test section with 24 m of the inner diameter and 1,500 mm of the length. The used polymer materials are two kinds of polyacrylamide[PAAM] and co-polymer[A611P]. The polymer concentration was varied with 50, 100 and 200 ppm under the same experimental conditions. Experimental results were shown that the drag is higher reduced by co-polymer rather than polyanylamide.

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