• 대한본초학회지
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• 제31권4호
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• pp.19-25
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• 2016

Objective : For the purpose of developing Korean herbology of the plants to Nymphaeaceae in Korea, the literatures of the successive generations have been thoroughly investigated to prepare this article.Methods : Books and research papers about Herbology which published at home and abroad were examined.Results : A list was made about Nymphaeaceae plant which were cultivated or grew naturally in Korea, after investigated the data on domestic and foreign Nymphaeaceae plants. Out of those lists, serviceable plants were selected and with those available plants, their distributions were analysed and parts which can be used as medicines were divided into 3 categories such as oriental medicine name, scientific name and non-official name. Nymphaeaceae's properties flavor, channels they use, effects, and toxicity were also noted. Nymphaeaceae (grew in Korea) were divided into 6 classes with 10 species. Out of those, 5 classes with 5 species were found serviceable which indicates 50% of all. Out of all 10 species of Nymphaeaceae family, Nuphar genus were found 4 species, which were shown the most. Among 5 genus of Nymphaeceae species, medicinal plants were all one species each. Out of all serviceable parts in Nymphaeaceae, Etc parts took first place as 10 species. There are no toxic, the survey said.Conclusion : There were totaled to 6 genera and 10 species in Dioscoreaceae in Korea and among them medicinal plants are 5 genera, 5 species, some 50% in total.

• 생약학회지
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• 제37권4호
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• pp.290-293
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• 2006

Phytochemical investigation of the seed extract of Nelumba nucifera Gaerth (Nymphaeaceae) resulted in the isolation of a plant hormon, dihydrophaseic acid (1), a abscisic acid derivative. The chemical structure of 1 was elucidated by 2D-NMR spectroscopic analysis, COSY, DEPT, HMQC and HMBC.

• Bulletin of the Korean Chemical Society
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• 제32권11호
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• pp.4083-4085
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• 2011

• Natural Product Sciences
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• 제15권2호
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• pp.90-95
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• 2009

Phytochemical investigation of the MeOH extract of the leaves of Nelumbo nucifera resulted in the isolation of five norsesquiterpenes, four flavonoids, two triterpenes and one alkaloid. Their chemical structures were characterized by spectroscopic methods to be (E)-3-hydroxymegastigm-7-en-9-one (1), (3S,5R,6S,7E)- megastigma-7-ene-3,5,6,9-tetrol (2), dendranthemoside B (3), icariside $B_2$ (4), sedumoside $F_1$ (5), luteolin (6), quercetin 3-0-${\beta}$-D-glucuronide (7), quercetin 3-0-${\beta}$-D-glucoside (8), isorhamnetin 3-0-rutinoside (9), alphitolic acid (10), maslinic acid (11), and N-methylasimilobine (12). Norsesquiterpenoids (1-5) and triterpenes (10-11) were isolated for the first time from this plant. Compounds 6 and 10-12 exhibited considerable cytotoxicity against four human cancer cell lines in vitro using a SRB bioassay.

• Natural Product Sciences
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• 제7권4호
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• pp.107-109
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• 2001

To investigate anti-diabetic component from the node of lotus rhizome (Nelumbo nucifera; Nymphaeaceae), activity guided isolation was conducted. One amino acid was isolated from active fraction of the aqueous methanolic extract. The structure of this compound was identified as tryptophan (1) by the analysis of spectroscopic evidences and comparisons with the data of authentic samples. Tryptophan reduced the blood glucose level significantly in glucose-fed hyperglycemic mice compared with glucose-treated group and exhibited 44.3% of activity compared with tolbutamide,.

• 약학회지
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• 제45권6호
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• pp.599-603
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• 2001

The node of lotus rhizome (Nelumbo nucifera, Nymphaeaceae) have been used as a traditional medicine for the remedy of hemorrhage, blood stagnancy and thirstiness. To investigate phenolic compound from the node of Nelumbo nucifera, phytochemical isolation and structure elucidation were conducted. Four phenolic compounds were isolated from aqueous methanolic extract and the structure of these compounds were identised as (+)-catechin (1), (+)-gallocatechin (2), (+)-gallocatechin (4u-8)-catechin (3) and scolpoletin (4) respectively by the analysis of spectroscopic evidences and comparisions with the data of authentic samples.

• Archives of Pharmacal Research
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• 제29권4호
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• pp.287-292
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• 2006

In this study, we isolated two new isorhamnetin glycosides, designated as nelumboroside A (3) and nelumboroside B (4), as well as the previously-characterized isorhamnetin glucoside (1) and isorhamnetin rutinoside (2), from the n-BuOH fraction of Nelumbo nucifera stamens. The structures of the two new compounds were then determined, using chemical and spectroscopic techniques. All isolated isorhamnetin glycosides 1-4 showed marked antioxidant activities in the DPPH, and $ONOO^-$ assays.

• 식물분류학회지
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• 제40권1호
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• pp.1-15
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• 2010

한 분류군의 진화의 역사를 파악하기 위해서는 분류군 내에서 가장 먼저 분지한 군(기저군)을 알아내는 것이 중요하다. 피자식물의 계통과 진화를 이해하고자 많은 식물학자들은 형태적 연구와 화석적 증거에 의해 현존하는 피자식물들 중 가장 먼저 분지하여 다른 모든 피자식물들과 자매군을 형성하는 분류군을 파악하려고 노력해 왔다. 최근 분자계통학의 기술적 발달과 자료의 축적으로 현생 기저 피자식물군에 대한 객관적 증거들이 제시되고 있다. 여전히 논쟁의 여지는 있지만, 대부분의 식물계통학자들은 1) 다수의 유전자들의 계통분석적 접근, 2) 복제된 두 유전자군의 계통수 네트웍 형성법, 3) 유전자의 구조적 접근 등의 분자적 증거에 의해 현생 기저 피자식물이 뉴칼레도니아에 자생하는 1과 1속 1종 식물인 Amborella trichopoda Baill.임에 동의하고 있다. 그러나 또 다른 가능성으로 Nymphaeaceae (수련과)와 A. trichopoda가 하나의 분계조를 형성하고 형성된 분계조가 다른 모든 피자식물의 자매군임을 지지하는 증거들도 일부 제시되어 현생 기저 피자식물에 대한 논쟁은 계속되고 있다. 현대 분자생물학적인 신기술의 발달은 대량의 분자적 자료를 제공하고 있어 이들 논쟁 해결의 실마리를 제공해 주고 있고, 진화적 모델식물로서의 Amborella 전체 유전체의 염기서열 결정과 이에 대한 파생연구는 Darwin이 지독하게 풀리지 않는 미스터리라 표현한 피자식물의 기원과 분화에 대한 해답을 제시해 줄 수 있을 것으로 기대된다.

• 생약학회지
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• 제44권1호
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• pp.1-5
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• 2013

Nelnumbo nucifera Gaerth. (Nymphaeaceae) has been used in a korean traditional medicine to treat fever, sunstroke and dizziness. The receptaculums of this plant were refluxed with MeOH, and then fractionated with organic solvents ($CH_2Cl_2$, EtOAc and n-BuOH) to screen whitening activity using tyrosinase inhibitory activity. EtOAc ($IC_{50}$, 45.23 ${\mu}g/ml$) fractions showed a good tyrosinase inhibitory activity. Column chromatographic separation of $CH_2Cl_2$ and EtOAc fractions of Receptaculum nelumbinis led to the isolation 3 compounds. Their chemical structures were characterized as ${\beta}$-sitosterol (1), quercetin 3-O-${\beta}$-D-galactopyranoside (2) and kaempferol 3-O-${\beta}$-D-glucopyranoside (3) by comparison NMR spectral data and with those in references, respectively. Isolated compounds 1 and 3 were firstly isolated from Receptaculums nelumbinis. Compounds 2 and 3 showed potent whitening activities.

• Natural Product Sciences
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• 제25권1호
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• pp.44-48
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• 2019

Nelumbo nucifera Gaertn. (Nymphaeaceae) is commonly called lotus and its leaves are widely been used as functional ingredients due to its antioxidant activity. For maximum efficacy, optimized extraction condition was established using response surface methodology. The high F-values, low p-values and insignificant p-value for lack-of-fit supported the fitness of the model and yielded the second-order polynomial regression for the antioxidant activity. The optimized extract was obtained by the extraction of 1 g of lotus leaves with 40 mL of 50% MeOH at $10.0^{\circ}C$, which exerted 70.1% antioxidant activity. Close correlation between phenolic content and antioxidant activity suggested phenolic compounds as active constituents of lotus leaves. In addition, comparison of different parts of lotus demonstrated the most potent antioxidant activity of flowers, followed by leaves and roots. Taken together, these results provide useful information about lotus leaves for the development as antioxidant ingredients. In addition, flowers and roots as well as leaves are suggested as good sources for antioxidant activity.