• Laboraroty Animal Research
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• 제33권2호
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• pp.57-67
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• 2017

The inhibitory effects of Asparagus cochinchinensis against inflammatory response induced by lipopolysaccharide (LPS), substance P and phthalic anhydride (PA) treatment were recently reported for some cell lines and animal models. To evaluate the hepatotoxicity and nephrotoxicity of A. cochinchinensis toward the livers and kidneys of ICR mice, alterations in related markers including body weight, organ weight, urine composition, liver pathology and kidney pathology were analyzed in male and female ICR mice after oral administration of 150, 300 and 600 mg/kg body weight/day saponin-enriched extract of A. cochinchinensis (SEAC) for 14 days. The saponin, total flavonoid and total phenol levels were found to be 57.2, 88.5 and 102.1 mg/g in SEAC, respectively, and the scavenging activity of SEAC gradually increased in a dose-dependent manner. Moreover, body and organ weight, clinical phenotypes, urine parameters and mice mortality did not differ between the vehicle and SEAC treated group. Furthermore, no significant alterations were measured in alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), blood urea nitrogen (BUN) and the serum creatinine (Cr) in the SEAC treated group relative to the vehicle treated group. Moreover, the specific pathological features induced by most toxic compounds were not observed upon liver and kidney histological analysis. Overall, the results of the present study suggest that SEAC does not induce any specific toxicity in the livers and kidneys of male and female ICR mice at doses of 600 mg/kg body weight/day.

• 응용통계연구
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• 제34권5호
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• pp.685-696
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• 2021

경제활동인구조사는 고용 관련 통계를 생성하는 국가조사로서, 국민의 경활상태(취업/실업/비경활)를 파악하는 것이 주요 목적이다. 정확한 통계를 내기 위해 무응답률을 낮추는 것이 중요하고, 이미 발생한 무응답을 보완하기 위한 방법으로 무응답 대체가 가능하다. 경제활동인구조사는 응답 방식이 순차적 흐름을 따라가기 때문에 구조적인 무응답이 존재한다. 또한 전체 가구원내 무응답 항목이 하나라도 있으면 해당 가족 구성원 전체를 무응답 처리하기에 최종 자료에는 항목 무응답이 아닌 단위 무응답만 존재한다는 특징이 있다. 본 연구에서는 구조적 무응답 이해 및 연계자료를 통한 과거 자료의 활용 등을 통해 기존의 방법보다 효과적인 무응답 대체 모형을 제시하고자 한다. 대체 모형의 성능을 일치도/비일치도를 기반으로 평가한다. 이를 위해, 2019년 11월 경제활동인구조사 자료를 기반으로 모의실험을 실시한다. 총 59,996명의 응답자 중 일부를 랜덤하게 선택한 뒤, 경활상태를 판정하는데 결정적인 설명변수 6개와 경활상태를 무응답 처리한다. 기존 무응답 대체 모형에서 사용하였던 설명 변수 이외에 산업변수와 종사상지위 변수를 추가함으로써 모형을 개선한다. 이는 과거자료의 연계 및 활용을 가정한 것으로, 기존의 모형모다 성능이 향상되는 것을 확인한다. 또한, 경활상태별 무응답자 수에 대한 다양한 시나리오를 고려한다.

• International Journal of Computer Science & Network Security
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• 제22권8호
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• pp.97-104
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• 2022

European integration processes have acted as a catalyst for the emergence of a new type of educational environment, which is characterized by competent flexibility of specialists. Therefore, the article focuses on professional training of teachers in the context of European integration processes using information technology and the search for innovative methods of training specialists. One of the educational priorities in Europe is to create a new model of a teacher who has an academic education, knows innovative methods, is able to perform functions and tasks efficiently and professionally, adequately, quickly and correctly respond to changes and innovations. The tasks facing education in the European dimension are formulated. The main trends in the education of teachers in modern Europe are described: the need to deepen and expand subject training programs in pedagogical institutions of Higher Education, which will allow autonomy of activity, awareness of responsibility for independent creative decisions, create favorable conditions for the development of professionalism through the use of Information Technology and the search for innovative methods of training specialists. At the present stage, various models of teacher training are being developed based on the University and practical concept using information technology and searching for innovative methods of training specialists. On this basis, two different theories of perception of teacher education were formed: as preparation of teachers for work throughout their professional career; as preparation for the first years of professional work, which is periodically repeated in the process of continuous professional training and improvement. Among the advantages that the use of Information Technology and the search for innovative methods of training specialists to implement the learning process, it is worth mentioning the following: simultaneous use of several channels of perception of the student or student in the learning process, thanks to which the integration of information processed by different sensory organs is achieved; the ability to simulate complex real experiments; visualization of abstract information by dynamic representation of processes, etc.

• Korean Journal of Acupuncture
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• 제40권3호
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• pp.79-89
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• 2023

Objectives : The purpose of this study is to investigate various application methods of focused ultrasound and apply them to clinical use in Korean medicine. Methods : Search was performed using the search engines of electronic databases, including PubMed, ScienceDirect, Cumulative Index to Nursing and Allied Health Literature (CINAHL), ScienceON, Oriental Medicine Advanced Searching Integrated System (OASIS), China National Knowledge Infrastructure (CNKI), Wanfang Data, Japan Science Technology Information Aggregator, Electronic (J-STAGE) and Citation Information by NII (CiNii), from inception to July 2023 without language limitation. Inclusion criteria were clinical studies including randomized controlled trials (RCTs), and animal experimental studies related with focused ultrasound treatments for acupoints or meridian sinews. Results : Total 17 papers, 7 for RCT, 6 for in vivo animal studies, and other experimental studies, were finally selected. Indications used in studies were shoulder pain, back pain, chronic back pain, and degenerative knee arthritis. In experimental studies, studies on animal models of hypoxic ischemic brain damage and hyperlipidemia were also conducted. As for the acupoints, LR3, LI4, and ST36 were used in clinical studies and, in animal experimental studies, GV20, KI1, and ST36 were used. As for the dose, 4 studies below 3 W/cm² and 3 studies in the range of 0.625 to 5 W/cm² in clinical studies, and all studies did not exceed 5 W/cm². In animal experimental studies, 0.5 W/cm², 2 W/cm², 7.5 WW/cm², 15 W/cm², 10~20 W/cm² were used. In all three studies describing the penetration depth during irradiation, it was less than 1 cm. Conclusions : We suggest that focused ultrasound is an appropriate treatment tool for stimulating the acupoints to transfer heat energy. Future studies with rigorous and well-designed RCTs for various diseases will be required to ascertain the focused ultrasound stimulate acupoints or meridian sinews.

• 서비스연구
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• 제13권1호
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• pp.176-185
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• 2023

본 연구는 산업현장 요양재해율 증가 및 중대재해처벌법 시행에 따라 산업재해 예방 대책의 필요성 차원에서 부각되고 있는 산업안전디자인의 도입시 경제적 성과를 측정하기 위한 모델을 개발하는 연구이다. 이를 위해서 이론 및 문헌연구 차원에서 산업안전관리와 산업안전디자인의 개념과 산업안전 분야에서의 경제적 성과 측정에 관한 연구를 수행하였다. 이론 및 문헌연구을 기반으로 사용자 의견 설문을 통하여 관련한 지표들의 초안에 대한 의견을 수렴하고, 전문가들을 대상으로 포커스그룹 인터뷰와 델파이기법을 수행하면서, 모델을 고도화하는 연구를 진행하였다. 객관성 확보를 위하여 회귀분석으로 산업안전디자인의 도입과 비용절감효과, 매출증대효과와의 인과관계를 검정하였다. 이와 같은 단계를 거쳐서, 최종적으로 1단계 재해손실비용 절감 효과 기반의 모델과 2단계 매출액 증대 효과 기반의 2가지 산업안전디자인의 경제적 성과측정 모델을 개발하였다. 실제 산업현장에 적용하기 위해서는 단순한 체크리스트를 넘어서는 산업안전디자인의 서비스 수준 계약 정도에 대한 표준으로써 제시될 수 있어야 한다.

• Journal of Preventive Medicine and Public Health
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• 제56권5호
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• pp.467-474
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• 2023

Objectives: Diabetes mellitus (DM) is a serious public health issue that places a heavy financial, social, and health-related burden on individuals, families, and healthcare systems. Self-reported health-related quality of life (HRQoL) is extensively used for monitoring the general population's health conditions and measuring the effectiveness of interventions. Therefore, this study investigated HRQoL and associated factors among patients with type 2 DM at a primary healthcare center in Indonesia. Methods: A cross-sectional study was conducted in Klaten District, Central Java, Indonesia, from May 2019 to July 2019. In total, 260 patients with DM registered with National Health Insurance were interviewed. HRQoL was measured with the EuroQol Group's validated Bahasa Indonesia version of the EuroQoL 5-Dimension 5-Level (EQ-5D-5L) with the Indonesian value set. Multivariate regression models were used to identify factors influencing HRQoL. Results: Data from 24 patients were excluded due to incomplete information. Most participants were men (60.6%), were aged above 50 years (91.5%), had less than a senior high school education (75.0%), and were unemployed (85.6%). The most frequent health problems were reported for the pain/discomfort dimension (64.0%) followed by anxiety (28.4%), mobility (17.8%), usual activities (10.6%), and self-care (6.8%). The average EuroQoL 5-Dimension (EQ-5D) index score was 0.86 (95% confidence interval [CI], 0.83 to 0.88). In the multivariate ordinal regression model, a higher education level (coefficient, 0.08; 95% CI, 0.02 to 0.14) was a significant predictor of the EQ-5D-5L utility score. Conclusions: Patients with diabetes had poorer EQ-5D-5L utility values than the general population. DM patients experienced pain/discomfort and anxiety. There was a substantial positive relationship between education level and HRQoL.

• Journal of Hospice and Palliative Care
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• 제10권3호
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• pp.128-136
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• 2007

목적: 본 연구는 전국 보건소에서 실시하고 있는 재가 암환자 관리사업에 대한 현황을 검토하고 사업수행 시의 장애요인을 파악한 후 재가암환자의 효율적 관리방안 개발을 목적으로 수행되었다. 방법: 2006년 7월부터 12월까지 총 6개월 동안 전국 225개 보건소를 직접 방문 및 전화 인터뷰를 통하여 현재 시행하고 있는 재가암환자 관리사업의 내용을 분석 하였다. 결과: 보건소 재가암환자 관리사업의 장애요인으로 환자의 보건소 암환자 관리에 대한 신뢰도 부족, 지역사회 맞춤형 프로그램 부재, 재가 암환자 관리 전담인력 및 차량부족, 재가 암환자 관리사업 담당자의 전문교육, 공중보건의의 문제점, 민간 의료기관과의 연계부족, 암환자 관련한 의료기관 및 호스피스 시설의 부재, 자원봉사자 비표준화 등으로 나타났다. 따라서 효율적 관리방안 중에서 특히 지역여건에 따른 유형별 관리시스템으로 보건소 직접수행 모델, 외부기관 위탁 모델, 외부기관과의 협력 모델을 제안하였다. 결론: 지역 특성에 따른 적절한 사업모델의 수행으로 각 보건소는 지역사회의 인적 물적 가용자원의 효율적 활용이 가능할 것으로 판단된다. 또한 이들 사업모델의 적용과 함께 지역사회 특유의 자체 프로그램의 개발로 재가 암환자 관리 사업의 효율성을 높일 수 있을 것으로 기대된다.

• 보건교육건강증진학회지
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• 제5권2호
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• pp.26-40
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• 1988

This survey was conducted to find out the present status of health education program being provided in primary schools focusing its planning, operation, contents and attitude of school nurses in September, 1988. Total 413 school nurses who are presently working in Seoul city was surveyed by mail and 167 school nurses who responded to the questionnaire were finally ana lysed. The following results were obtained. 1. The general charcteristics of the school nurses′ surveyed. As for age distribution, 30-40 age group was 60.4％ the highest and the mean age was 30. 13. As for educational attainment, junior nursing college was 71.9％. 68.3％ of the surveyed was married and 43.1％ of them has 5-10 years of working experiences. As for schools where school nurses are presently working, 31.7％ has 2,000-3,000 students, 22.8％ has 50-60 classes and 5 schools have more than 80 classes. 2. Planning of a school health education School health education was planned every semester in 55.7％, which was the highest. As for utilization status of the materials for planning of a school health education as a referance, 86.8％ of the total respondants utilized the guidelines published by Seoul city School nurses′ Association, and the administrative guidelines for school health, textbooks, school health statistics and articles related to school health in order. It was tried whether the number of referances being utilized was related to the working experiences. It was found that the shorter the experiances, the more materials were utilized. It was answered that teaching plan for health education was prepared by school-nurses themselves (95.2％), and was differentiated as three levels as the first and second grades, the third and fourth grades, and the fifth and sixth grades 3. The contents of the school health education 16 subjects offered to 6 grades of students were surveyed as follows. As for fifth and sixth grades, contents on growth and development was most widely provided as 54.5％, and 68.9％, respectively. And the next to this subject, dental health education was also frequently offered to the second, third and fourth grades as 50.9％, 68.9％, and 47.3％, respctively. 4. The operation of school health education Health education provided by school nurses was conducted formallu in 36.6％, and formally of informally accordin to grades in 43.9％. It was answered that 50.3％ of the surveyed school had started health education from 1987, when the plan for activation of school health was ordered from. Educational Committee. Teaching hours of school nurses was 6 in 32.9％, which was the highest. The lesson was provided for class unit in 77.2％, and sex education was sometimes offered to male and female students separately. As for support of health personnels out of school for health education, 79.0％ did not receive any support. If there were any aids out of school, 62.9％ received them from other related agencies and 74.3％ anwered that it was once in a semester. As for expenses for health education, 57.3％ did not input any expenses alloted to school health program as a whole. As audio-visual materials, slides were utulized most frequently and models, and charts in order. 5. Awareness of school nurses on the operation of school health education School nurses evaluated their educational quality as a health educator subjectively, 60-70％ of them answered to be average in 4 domains such as knowledge, educational skill, ability to prepare teaching plan, and cooperation. As for the awareness on the support and cooperation of the higher institutions, 46.4％ -61.8％ answered that "so and so" toward Ministry of Education and Ministry of Affairs, and 13-37％ "not supportive" Teachers of the corresponding schools were answered to be "so and so" in 55.9％-56.7％, and "very supportive" in 33.34％. There was a significant difference in formality of the lesson according to the support of the superintendent.

• Asia pacific journal of information systems
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• 제21권3호
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• pp.71-96
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• 2011

Within the traditional medical delivery system, patients residing in medically vulnerable areas, those with body movement difficulties, and nursing facility residents have had limited access to good healthcare services. However, Information and Communication Technology (ICT) provides us with a convenient and useful means of overcoming distance and time constraints. ICT is integrated with biomedical science and technology in a way that offers a new high-quality medical service. As a result, rapid technological advancement is expected to play a pivotal role bringing about innovation in a wide range of medical service areas, such as medical management, testing, diagnosis, and treatment; offering new and improved healthcare services; and effecting dramatic changes in current medical services. The increase in aging population and chronic diseases has caused an increase in medical expenses. In response to the increasing demand for efficient healthcare services, a telehealth service based on ICT is being emphasized on a global level. Telehealth services have been implemented especially in pilot projects and system development and technological research. With the service about to be implemented in earnest, it is necessary to study its overall acceptance by consumers, which is expected to contribute to the development and activation of a variety of services. In this sense, the study aims at positively examining the structural relationship among the acceptance factors for telehealth services based on the Technology Acceptance Model (TAM). Data were collected by showing audiovisual material on telehealth services to online panels and requesting them to respond to a structured questionnaire sheet, which is known as the information acceleration method. Among the 1,165 adult respondents, 608 valid samples were finally chosen, while the remaining were excluded because of incomplete answers or allotted time overrun. In order to test the reliability and validity of the assessment scale items, we carried out reliability and factor analyses, and in order to explore the causal relation among potential variables, we conducted a structural equation modeling analysis using AMOS 7.0 and SPSS 17.0. The research outcomes are as follows. First, service quality, innovativeness of medical technology, and social influence were shown to affect perceived ease of use and perceived usefulness of the telehealth service, which was statistically significant, and the two factors had a positive impact on willingness to accept the telehealth service. In addition, social influence had a direct, significant effect on intention to use, which is paralleled by the TAM used in previous research on technology acceptance. This shows that the research model proposed in the study effectively explains the acceptance of the telehealth service. Second, the research model reveals that information privacy concerns had a insignificant impact on perceived ease of use of the telehealth service. From this, it can be gathered that the concerns over information protection and security are reduced further due to advancements in information technology compared to the initial period in the information technology industry, and thus the improvement in quality of medical services appeared to ensure that information privacy concerns did not act as a prohibiting factor in the acceptance of the telehealth service. Thus, if other factors have an enormous impact on ease of use and usefulness, concerns over these results in the initial period of technology acceptance may become irrelevant. However, it is clear that users' information privacy concerns, as other studies have revealed, is a major factor affecting technology acceptance. Thus, caution must be exercised while interpreting the result, and further study is required on the issue. Numerous information technologies with outstanding performance and innovativeness often attract few consumers. A revised bill for those urgently in need of telehealth services is about to be approved in the national assembly. As telemedicine is implemented between doctors and patients, a wide range of systems that will improve the quality of healthcare services will be designed. In this sense, the study on the consumer acceptance of telehealth services is meaningful and offers strong academic evidence. Based on the implications, it can be expected to contribute to the activation of telehealth services. Further study is needed to assess the acceptance factors for telehealth services, such as motivation to remain healthy, health care involvement, knowledge on health, and control of health-related behavior, in order to develop unique services according to the categorization of customers based on health factors. In addition, further study may focus on various theoretical cognitive behavior models other than the TAM, such as the health belief model.

• 한국학교ㆍ지역보건교육학회지
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• 제5권
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• pp.107-122
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• 2004

To correctly plant the value of sex to the juvenile, we cannot overemphasize the importance of the sexual education in schools. Therefore, the study for teachers' consciousness and view of sex is also necessary, because they are subjects of education and role-models of sex of their students. Especially, if teachers are over fifty in age, it is more important, because it is obvious, as they are in positions of managers and directors of education, that their view of sexual value and consciousness are influencing the aim of education and the course of education. Hereby this study was conducted to check their sexual consciousness, attitude, and condition and to prepare for the basic data needed for the development of a sexual education program suitable to them. The methods of the survey of this study are applied by modifying or supplementing those of precedented studies. They are used after analyzing reliance of items according to Cronbach's $\alpha$ figure calculating law, and modifying or supplementing items lower in reliance. The questionnaire survey was conducted among 1,000 randomly selected from teachers working in middle and high schools in Korea from June 14th in 2004 to June 30th. The survey analyzed 632 questionnaires suitable to it. The outcomes of the survey of this study are like the following: First, the objects of the survey consist of 64.6% men and 35.4% women. Among them, 41.1% are under fifty and the rest are over fifty. As for the periods of marriage, 15.5% are unmarried, 16.3% are under ten years, 18.0% are between ten and twenty, and 50.2% are over twenty. Second, with reagard to sex, 25.6% admit the necessity of a heterosexual friend. 32.0% say that they are conservative to sex. 54.1% are taught sexual education. 67.1% attribute sexual education to nursing teachers. Third, among those who answer that they enoughly know the concept of sex, seenig by age, 25.0% are under fifty and 58.1% are over fifty. Seening by the periods of marriage, 9.2% are unmarried, 28.2% are under ten, 49.1% are between ten and twenty, and 59.0% are over twenty. Among those who answer that they enoughly know the concepts of sexual harassment and sexual violence, seenig by age, in the turns by above-mentioned order, each 47.7% and 76.3%. Seening by the periods of marriage, each 9.2%, 28.2%, 49.1%, and 59.0%. Fourth, among those who answer that "teachers also need sexual education and sexual counsel," by age, each92.7% and 91.4%. By the periods of marriage, each 89.8%, 95.2%, 89.4%, and 92.4%. As a matter of course, we can infer the necessity of the sexual education and sexual counsel for teachers. Fifth, among those who answer that they are satisfied with their sexuality, by age, each 41.1% and 61.3%. By the period of marriage, each 4.1%, 63.1%, 64.1%, and 61.5%. As for the sexual desire like spiritual intercourse, physical intercourse containing sexuality, by age, each 71.9% and 93.5%. By the periods of marriage, each 54.0%, 81.5%, 90.3%, and 93.0%. The survey shows that those over fifty and having long marriage are feeling the stronger desire towards sexuality. Through the outcomes of this survey, a few suggestions are possible: First, it is necessary to check of the teachers' view of sexual value and to study deep about the sexual tendency of them in twenties, thirties, and forties. It is to make them teach their students on the firm basis, and also to develop suitable sexual education and counsel program.