• Journal of Technologic Dentistry
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• v.33 no.4
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• pp.369-378
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• 2011

Purpose: This study was carried out for the purpose of obtaining basic data necessary for developing the future oral health promotion program of the elderly by surveying the actual condition of managing dental prosthesis in the elderly. Methods: It collected materials targeting 346 elderly brackets in over 65 years old who dwell in Seoul and Gyeonggi-do Province for about 10 months from September 2010 to June 2011, analyzed 312 copies except 34 copies, which are inappropriate for data processing due to being insufficient in response among these things, and obtained the following results. Results: In the actual condition of missing tooth, a case of missing tooth was indicated to be 78.8%. In case of missing tooth, the number of missing teeth was indicated to be 75.6% for under 5 pieces and 19.1% for over 21 pieces. In the actual condition of managing prosthesis, a case with dental prosthesis treatment was indicated to be 77.6%. A kind of prosthesis was indicated to be the highest in fixed partial dentures with 36.5%. In a method of rinsing dentures, 47.7% of the elderly responded as saying of washing it out with water. The appearance of removing dentures at night was indicated to be the highest in doing so with 63.1%. Satisfaction with prosthesis of being mounted now was indicated to be moderate with 50.4%. As for the appearance of having experience of education on how to manage prosthesis, it was indicated to be high with 50.4% in having none. In a kind of prosthesis depending on averagely monthly income, the ratio of total dentures was high when averagely monthly income is low. On the other hand, a case with high income was indicated to have high ratio in implants. The satisfaction with prosthesis was low when averagely monthly income is low. Also, in the experience of education on how to manage prosthesis, the ratio of responses as saying of having no experience of education on how to manage prosthesis was indicated to be high when averagely monthly income is low. Conclusion: Examining the above results, a developmental plan is considered to be necessary such as developing continuous and systematic oral health promotion program for managing elderly people's managing dental prothesis.

• Journal of Periodontal and Implant Science
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• v.48 no.6
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• pp.347-359
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• 2018

Purpose: Periodontitis and rheumatoid arthritis (RA) share a similar inflammatory pathogenesis. Porphyromonas gingivalis (Pg) can induce anticyclic-citrullinated peptide autoantibodies (anti-CCP antibodies), a key factor in the development of RA. This study aimed at evaluating the relationships between the 2 diseases and identifying the clinical implications thereof, with a focus on periodontal pathogens in Korean adults. Methods: A total of 260 RA patients and 86 age- and sex-matched control patients without arthritis were enrolled in this prospective cross-sectional study. Periodontal indices and the prevalence and amount of periodontal pathogens were compared between the groups. Correlations between periodontal and RA indices were examined, as were correlations between 9 periodontal pathogens and RA indices. Results: The RA group had significantly higher values than the control group for all investigated periodontal indices (P<0.05) except the number of teeth. The gingival index (GI) was correlated with the disease activity score 28 (DAS28) (r=0.125, P=0.049), RA disease duration (r=0.253, P<0.001), erythrocyte sedimentation rate (ESR) (r=0.162, P=0.010), and anti-CCP antibody titer (r=0.205, P=0.004). Probing pocket depth (PPD) was correlated with ESR (r=0.139, P=0.027) and anti-Pg antibody titer (r=0.203, P=0.001). Bleeding on probing (BOP) was correlated with DAS28 (r=0.137, P=0.030), RA disease duration (r=0.202, P=0.001), ESR (r=0.136, P=0.030), anti-Pg antibody titer (r=0.177, P=0.005), and anti-CCP antibody titer (r=0.188, P=0.007). Clinical attachment level (CAL) and periodontitis severity were correlated with anti-Pg antibody titer (the former r=0.201, P=0.002; the latter r=0.175, P=0.006). The quantity of Pg was positively correlated with the serum anti-Pg antibody titer (r=0.148, P=0.020). Conclusions: The GI, BOP, and PPD showed positive relationships with several RA indices. The anti-Pg antibody titer had positive relationships with PPD, BOP, CAL, and periodontitis severity. Thus, increasing values of periodontal indices could be used as a risk indicator of disease development in RA patients, and an increasing anti-Pg antibody titer could be considered as a warning sign in RA patients suffering with periodontitis.

• Journal of the korean academy of Pediatric Dentistry
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• v.34 no.3
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• pp.468-472
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• 2007

The Wiskott-Aldrich Syndrome (WAS) is an inherited immunodeficiency caused by a variety of mutations in the gene encoding the WAS protein (WASp). First described in 1937 by Wiskott, the incidence of WAS has so far been estimated at 4 in 106 live births. The Wiskott-Aldrich Syndrome is an X-linked condition characterized by 1) an increased tendency to bleed caused by a reduced number of platelets, 2) recurrent bacterial, viral and fungal infections, and 3) eczema of the skin. The purpose of this report is to present cases highlighting the clinical features of the syndrome and the required considerations in the treatment of patients. The report consists of two particular cases: a 2-year-11-month-old boy seen for a routine oral examination prior to his bone marrow transplantation and a 2-year-6-month-old boy with herpes gingivostomatitis and teeth discoloration.

• Journal of Korean society of Dental Hygiene
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• v.15 no.2
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• pp.271-278
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• 2015

Objectives: The aim of this study was to investigate the effect of water fluoridation program(WFP) on dental caries prevention in Ulsan, Korea. Methods: The data of control group were extracted from 2012 Korean National Oral Health Survey(KNOHS). Since 1998, WFP was implemented in Ulsan. The subjects were 670 subjects including 10 to 12-years old children in 2009. The control subjects were 4,871 people in non-fluoridated metropolitan cities comparable to Ulsan. The control subjects were selected from 2012 KNOHS. A self-reported questionnaire was completed by the variables including oral health behaviors on daily frequency of toothbrushing, eating snacks and beverages. Oral health examination was carried out by two dentists who received a training in KNOHS with an inter-examiner-agreement. Caries preventive fraction was calculated by the difference of DMFT and DMFS index. The preventive effects of the WFP program were focused on gender, number of fissure sealed teeth, daily frequency of toothbrushing, eating snacks and beverages. Data were analyzed using SPSS $19.0^{(R)}$(SPSS Inc., Chicago, IL, USA) statistical package. Results: DMFT indices of 12-year-old subjects(n=670) in WFP and control population(n=4,871) were 2.11 and 1.23, respectively with an estimated prevention effect of 41.7%. Conclusions: WFP in Ulsan reduced the prevalence of dental caries. WFP should be recommended for the public oral health program in other metropolitan cities.

• Journal of Periodontal and Implant Science
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• v.26 no.1
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• pp.47-67
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• 1996

The purpose of this study was to observe the effect of $Biocoral^R$ graft and bioglass 45S5 graft in combination with ePTFE membrane in periodontal osseous defects for new bone formation. Nine healthy dogs were used. Under general anesthesia, 3-wall defects were created on the mesial and distal surfaces of the maxillary right canines, the mesials of the maxillary right second premolars, the distals of the mandibular right canines and the mesials of the mandibular right third premolars. To induce periodontitis, a silicone rubber, $Provil^R$ light body, was injected under pressure into the defects. Ninety days later, $Provil^R$was removed and followed by thorough root planing. The followings were then applied in the mesial and distal defects of the maxillary right canines, the mesials of the maxillary right second premolars, the distals of the mandibular right canines and the mesials of the mandibular right third premolars by random selections : 1) ePTFE membrane only application, 2) $Biocoral^R$ graft, 3) $Biocoral^R$ graft and ePTFE membrane application, 4)Bioglass 45S5 graft, 5) Bioglass 45S5 graft and ePTFE membrane application. The membranes were removed 1 month later. The dogs were sacrified at 1, 2 and 3 months following the graft, and block sections were made, demineralized, embedded, stained and examined by light microscope and transmission electron microscope. On the sections from teeth treated with ePTFE membrane only, the defect demonstrated extensive connnective tissue and alveolar bone regeneration. The $Biocoral^R$ graft group demonstrated extensive bone regeneration compared with ePTFE membrane only group. In the $Biocoral^R$ graft plus ePTFE membrane group, regeneration of new alveolus and crest occurred within the defect. As the experimental period lengthened, bone regeneration was increased and bone bridge was formed among the graft particles. The but bioglass 45S5 graft group demonstrated extensive bone regeneration but the amount of new bone was less than that of the $Biocoral^R$ graft group. For the bioglass 45S5 graft plus ePTFE membrane group, the amount of new bone was also increased. As the experimental period lengthened, bone regeneration was increased. Multinucleated giant cells, fibroblasts and macrophages were observed. As the bone formation was increased, the number of such cells was decreased. In conclusion, the $Biocoral^R$ was found better than the bioglass 45S5 for new bone formation, and the use of ePTFE membrane alone or with $Biocoral^R$/bioglass 45S5 can be supported as potential methods of promoting bone formation.

• Journal of Korean society of Dental Hygiene
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• v.9 no.2
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• pp.137-146
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• 2009

In pediatric dentistry, sedation therapy is one of methods for managing children's behavior, and various types of sedation therapy are being used. Thus, this study surveyed the awareness of and satisfaction with sedation therapy in 204 parents who visited the Pediatric Dentistry using a self-administered questionnaire during the period from June to December 2008 in order to get information necessary in behavior management for pediatric patients, and obtained results as follows. 1. The most common path of learning about sedation therapy was dentistry (49.5%), and the most common reason for choosing sedation therapy was 'The child was young'(42.3%), which was followed by 'The child is too afraid'(18.8%), 'There are many teeth to be treated'(16.0%), 'To adjust the number of visits'(11.3%), and 'For behavior management'(3.1%). 2. Most of the parents felt anxiety about sedation therapy, and the reasons for the anxiety were 'The child was young'(33.0%), 'Worry about side effects'(31.3%), 'Worry about recovery of consciousness'(25.7%), 'Worry about the blunting of intellectual abilities'(7.6%), and others (2.4%). 3. Satisfaction with sedation therapy was higher in men than in women, and was high in order of 'Stationing of an anesthetist', 'One time completion of treatment', and 'Cautions'. Statistically significant difference was observed between men and women only in question "Have you ever heard about sedation therapy?"(p=0.018). 4. According to age, satisfaction with sedation therapy was highest in parents whose child was less than 48 months old. Satisfaction was high in order of 'Stationing of an anesthetist', 'One time completion of treatment', and 'Cautions', 'Choice of sedation therapy', and statistically significant difference was observed according to age only in question "Have you ever heard about sedation therapy?"(P=0.005). 5. Positive correlation was observed among questions on satisfaction with sedation therapy. In the survey on the awareness of and satisfaction with sedation therapy in parents visiting the dentistry, awareness and satisfaction were generally high with regard to the parents' choice of sedation therapy, but many of the parents answered that they chose sedation therapy and felt anxiety because their child was young. The results of this study need to be considered for behavior management in pediatric dentistry and there should be systematic education and promotion of sedation therapy.

• Journal of Periodontal and Implant Science
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• v.30 no.1
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• pp.111-120
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• 2000

Purpose We designed this study for the purpose of determining the relationship between periodontal disease activity and PLBW, using the evaluation of probing pocket depth, loss of attachment, gingival index, gingival crevicular fluid amount and subgingival microflora. Methods A total of 100 volunteer mothers(mean age 30.44) at the Department of Obstetrics and Gynecology Seoul National University Hospital were selected for this study.Pregnancy outcomes were categorized into cases and controls in two ways. our definition was based on the following; Group 1 : Any PLBW cases Vs. All NBW controls Group 2 : PLBW cases Vs. NBW controls A periodontal exam was performed on the Ramfjord( #16, 21, 24, 36, 41, 44) teeth and Clinical evaluation consisted of probing pocket depth, loss of attachment, gingival index and gingival crevicular fluid amount. Subgingival plaque samples were collected by three sterile #35 paper points. The total number of anaerobic colonies and aerobic bacteria were enumerated after incubation. Antisera to P. gingivalis, P. intermedia, A. actinomycetemcomitans were produced in white rabbits with live whole cells suspensions. The specific fluorescent bacteria obtained by immunofluorescence and total cell counts obtained by dark-field microscopy were counted on four fields. The percent of each specific microorganism in the total cell count was determined. Results Any PLBW and PLBW cases showed significantly greater probing depth and attachment loss than all NBW and NBW controls. Cases group had significantly increased anaerobic bacterial counts compared with control group and no differences in the other microbes. This study confirmed that periodontal disease is a statistically significant risk factor for PLBW by investigating clinical parameters and subgingival plaque analysis.

• Journal of the korean academy of Pediatric Dentistry
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• v.24 no.1
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• pp.204-219
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• 1997

The use of fluoride is one of the most effective methods for caries prevention. Fluoridation of public water supply has been recognized, for many years, as an effective way to reduce dental caries. The fluoride supplement has been recommended when the natural fluoride was unavailable or below the optimal range. However the mechanism of caries prevention by fluoride has not yet been clarified and it is well known that an overdose of fluoride results inacute and chronic toxicity, especially dental fluorosis. Fluoride mouthrinsing solution is widely used in dentistry due to its effectiveness in carrying anticariogenic action. Understanding the effects of fluoride mouthrinsing solution on human gingival fibroblasts will provide the safety rationale for its use during the caries preventive therapy. The purpose of this study was to evaluate the cytotoxic effect of fluoride mouthrinsing solution on the human gingival fibroblast in vitro. The human gingival fibroblasts were cultured from healthy gingiva on the extracted deciduous teeth of children. Cells were inoculated into a 24-well plate with $1{\times}10^4cells/well$ of medium at $37^{\circ}C$, 100% humidity, 5% $CO_2$ incubator for 24 hours. And the cells were counted by using the hemocytometer at each designed study. Human gingival fibroblasts were cultured in growth medium after one minute application range of 0.02%-0.2% NaF solution and 0.1% $SnF_2$ solution. The cells used in this study were between fifth to eighth passage number. The cell morphology was examined by inverted microscope and cell proliferation was measured by incorporating $[^3H]$-thymidine into DNA. DNA synthesis by human gingival fibroblasts was assessed by $[^3H]$-thymidine uptake assays while the cell activity was measured by MTT assay. Each concentrated fluoride mouthrinsing solution was estimated for its biocompatability with fibroblasts by the tissue culture technique. The results of this study were as follows : 1. It was observed that at 0.05%, 0.2% NaF mouthrinsing solution the cytoplasmic processes became globular. When 0.1% $SnF_2$ mouthrinsing solution was applied, the cytoplasmic process and cell morphology were disappeared. 2. DNA synthetic activity was reduced regardless of the concentration of the fluoride mouthrinsing solution. However, the result is statistically insignificant except 0.1% $SnF_2$ mouthrinsing solution(p<0.05). 3. Our results indicate that 0.02%, 0.05% concentrations of NaF mouthrinsing solution caused minimal cytotoxicity. But 0.2% NaF and 0.1% $SnF_2$ concentration were a significant difference between the cell activity in the experimental group and control group (p<0.05). 4. After appling 0.05% & 0.02% NaF fluoride mouthrinsing solution, cell activity was restored to the control groups level according to incubating time. The results suggest that direct exposure to fluoride solution inhibits gingival fibroblast activity. Therefore, for the most effective use of fluoride use, lowering the concentration of fluoride mouthrinsing is advisable because it maintains biocompatability and free ion in the oral fluid.

• Journal of the korean academy of Pediatric Dentistry
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• v.26 no.2
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• pp.275-283
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• 1999

Authors evaluated 152 patients at the department of Pediatric Dentistry in Seoul National University Hospital through clinical records and radiographs. And the following features were studied ; age, sex distribution, number of mesiodens per patients, location, status of eruption, shape and orientation of crown, and complication. From the above results, the relationship between features of mesiodens and complications were evaluated using chi-square analysis. 1. Complications due to the presence of mesiodens did not occur in 31.6%, delayed eruption of adjacent teeth was observed in 33.6%, midline diastema in 22.4%, rotation in 8.6%, displacement in 3.3%, and crowding in 0.7% of all evaluated patients. 2. As compared with the above 8.5 year group, in the under 8.5 year group, the frequency of complications was significantly higher(P<0.05). As compared with those positioned lingually, in mesiodens labially or within the arch the frequency of complications was significantly higher(P<0.01). Also, the frequency of complications was significantly higher when the mesiodens was tuberculate in form(P<0.05). 3. Of the 104 patients with complications, the frequency of delayed eruption was significant higher in the under 8.5 year group, and in above 8.5 year group, the frequency of malocclusion was significantly higher(P<0.05). When mesiodens were located in the midline region, the frequency of malocclusion was significant higher, while in case with laterally positioned mesiodens the frequency of delayed eruption was significantly higher(P<0.01).

• Journal of the korean academy of Pediatric Dentistry
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• v.34 no.3
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• pp.481-489
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• 2007

Maxillary canine impaction is a frequently encountered clinical problem, and it may cause the resorption of adjacent tooth or cystic change. Treatment plan for maxillary canine impaction should be decided among extraction, orthodontic traction and autotransplantation according to several factors such as direction and position of unerupted tooth, degree of developing root apex, eruption space, exsitance of supernumerary tooth, odontoma, or cyst. Autotransplantation is a valuable alternative to extraction of impacted teeth, where surgical exposure and subsequent orthodontic realignment are difficult or impossible due to unfavorable impaction position. And its prognosis is dependent on a number of factors such as preservation of periodontal ligament, degree of root development, surgical technique, patient's age, endodontic treatment, time and type of splinting and storage medium, etc. The patients in these cases visited our dental clinic in the late permanent dentition with the chief complaint of unerupted maxillary canines. And it was thought that the spontaneous eruption guidance or orthodontic traction and alignment were difficult because of its unfavorable impacted position. Therefore, autotransplantaion and endodontic treatment were done and have been checked periodically until now.