• The Korean Journal of Zoology
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• v.34 no.3
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• pp.426-431
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• 1991

The present study examines the effect of naloxone, mu-opioid receptor antagonist, on prolactin (PRL) gene expression and secretion induced by estradiol (I) treahent in vivo. Adult rats were ovariectomized (OW) and implanted with Silastic capsules containing either vehicle (oil) or E. Three days later, NAL (2 mg/kg BW) or saline urere injected 30 min prior to sacrifice. To examine PRL secretion in vitro, the pituitaries were incubated in the superfusion system for 3 hrs. Superfusates were collected at 10 min intenrals on ice and subjected to PRL radioimmunoassay. Endogenous release of PRL in OU( + I rats was signifcantlv higher than that in OVX rats (mean $\pm$ SE; 24.5 $\pm$ 3.1 vs 14.5 $\pm$ 2.9 ns/10 min). A single injection of NAL clearly inhibited PRL release in Nitro from pituitaries derived from OW + I rats, but not from OW group. PRL myNA was determined by RNA-blot hybridisation assay with nicktranslated PRL CDNA. E stimulated PRL mRNA about 3 fold over that shown in OW group. Treahent of NAL suppressed the I-stimulated PRL myNA in OVX + I group, but not in OVX group. These data clearly showed that the NAL-induced inhibition of PRL secretion was well correlated with changes in PRL mRNA level and this inhibitory process appears to be mediated in I-dependent manner.

• Current Optics and Photonics
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• v.1 no.4
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• pp.402-411
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• 2017

Combined LIBS-Raman spectroscopy has been widely studied, due to its complementary capabilities as an elemental analyzer that can acquire signals of atoms, ions, and molecules. In this study, the classification of polymorphs was performed by laser-induced breakdown spectroscopy (LIBS) to overcome the limitation in molecular analysis; the results were verified by Raman spectroscopy. LIBS signals of the $CaCO_3$ polymorphs calcite and aragonite, and $CaSO_4{\cdot}2H_2O$ (gypsum) and $CaSO_4$ (anhydrite), were acquired using a Nd:YAG laser (532 nm, 6 ns). While the molecular study was performed using Raman spectroscopy, LIBS could also provide sufficient key data for classifying samples containing different molecular densities and structures, using the peculiar signal ratio of $5s{\rightarrow}4p$ for the orbital transition of two polymorphs that contain Ca. The basic principle was analyzed by electronic motion in plasma and electronic transition in atoms or ions. The key factors for the classification of polymorphs were the different electron quantities in the unit-cell volume of each sample, and the selection rule in electric-dipole transitions. The present work has extended the capabilities of LIBS in molecular analysis, as well as in atomic and ionic analysis.

• Current Optics and Photonics
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• v.4 no.3
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• pp.238-246
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• 2020

The heat distribution in crystals in a 2-㎛ acousto-optic Q-switched Tm:LuAG laser pumped by pulsed-laser-diode (pulsed-LD) intermittent-pumping technology was analyzed using COMSOL software. The thermal lensing effect of the Tm:LuAG crystal can be mitigated by pulsed-LD intermittent-pumping techniques. An experimental setup using this kind of approach achieved maximum output energy of 8.31 mJ, minimum pulse width of 101.9 ns, and highest peak power of 81.55 kW, reached at a Q-switched repetition rate of 200 Hz. It offers significant improvement of performance of the output laser beam, compared to pulsed-LD double-ended pumping technology at the same repetition rate.

• Proceedings of the IEEK Conference
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• 2006.06a
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• pp.149-150
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• 2006

In this paper, design, simulation, fabrication method, and measured results of a digital frequency discriminator(DFD) operating in E, F, and G band are introduced. We describe the direct conversion scheme(DCS) with microwave integrated-circuit(MIC) developed for the small-area and high-speed system. When the input signal is the pulse with a pulse width of 100 ns, accuracy of frequencies measured by the DFD has 1.335 MHz RMS at no noise and 2.64 MHz RMS at signal-to-noise(S/N) ratio within 3 dB in E, F, and G band, which nearly satisfy the specification of 2.5 MHz RMS.

• IEMEK Journal of Embedded Systems and Applications
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• v.13 no.2
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• pp.83-91
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• 2018

With the development of IT (Information Technology) technology, embedded system and network technology are combined and used in various environments such as military environment as well as everyday life. In this paper, we propose a new airdropped distributed mobility model (ADMM) modeling the dispersion falling of the direct shot of a cluster bomb, and we compare and analyze some representative MANET routing protocols in ADMM in ns-3 simulator. As a result of the analysis, we show OLSR routing protocol is promising in ADMM environment in the view points of packet delivery ratio (PDR), end to end delay, and jitter. In addition, we propose a new adaptation scheme for OLSR, AND-OLSR (Average Node Distance based adaptive-OLSR) to improve the original OLSR in ADMM environment. The new protocol calculates the average node distance, adapts the period of the control message based on the average node distance increasing rate. Through the simulation study, we show that the proposed AND-OLSR outperforms the original OLSR in PDR and control message overhead.

• Bulletin of the Korean Chemical Society
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• v.23 no.12
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• pp.1769-1772
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• 2002

Previous $^{19}F\;and\;^{1,2}H$ electron-nuclear double resonance (ENDOR) study of fluorometmyoglobin (MbF) in frozen-solution state provided sensitive tools sensing subtle structural changes of the heme that are not obtainable from X-ray. [Fann et al., J. Am. Chem. Soc. 1995, 117, 6019] Because of the intrinsic inhomogeneouse EPR line broadening effect of MbF in frozen-solution state, detection of the intrinsic inhomogeneouse EPR line broadening effect of MbF in frozen-solution state, detection of the electronic and geometrical changes of the heme ring itself and the proximal histidine by using $^{14}N$ CW ENDOR was interfered. In the present study, hyperfine-sensitive $^{14}N$ Mims ENDOR technique of pulsed-EPR was employed to probe the changes. With two different $\tau$ values of 128 and 196 ns, $^{14}N$ ENDOR signals of the heme and proximal histidine were completely resolved at $g'_{II}(=g_e=2)$. This study present that X-band $^{14}N$ Mims ENDOR sequence can sensitively detect the small changes of the spin densities and p orbital populations of the proximal and the heme nitrogens, caused by ligand and pH variation of the distal site.

• Proceedings of the KIPE Conference
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• 2019.11a
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• pp.46-48
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• 2019

본 논문은 Discontinuous Conduction Mode(DCM) 플라이백 컨버터로 생성한 고전압 펄스를 스파크 갭으로 펄스 상승 시간을 줄이는 방법에 관하여 다룬다. 이러한 방법으로 생성된 빠른 상승률 특성을 가지는 고전압 펄스 전원장치는 친환경 가스 처리 분야에 사용할 수 있다. 기존 스태킹 구조의 펄스 전원 장치는 많은 수의 스위치들과 에너지 저장 소자가 필요하므로 부피가 커지고 제조 단가가 증가하는 반면, 분 논문에 제안된 전원 장치는 구조를 단순화하여 전체 시스템의 소형화 및 제조 단가를 낮춘 점을 특징으로 한다. 제안된 설계 토폴로지는 플라이백 변압기 2차 측에 다이오드의 사용 유무에 따라 두 개의 변형된 회로로 응용 가능 하다. 변압기 2차측에 다이오드를 사용하면, 음의 성분 없이 깨끗한 고전압 출력 펄스를 만들 수 있지만 사용한 다이오드의 전압 정격을 고려해야 한다. 다이오드를 사용하지 않는다면, 고전압 출력 펄스에 음의 성분이 발생하지만 비용과 부피를 최대한 줄일 수 있다. PSIM 시뮬레이션을 사용하여 제안하는 전원 장치의 23kV, 0.5 ㎲, 10 ns rising time의 출력 펄스 발생 성능을 검증하고, 다이오드 사용에 따른 출력 펄스의 차이점을 비교하였다.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.12 no.6
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• pp.23-29
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• 2013

In this paper, pure $I_{ph}$ and hybrid carbon nanotube reinforced $I_{ph}$ were sintered using the SPS(spark plasma sintering) method for high densification. A nanosecond laser (${\lambda}=1063nm$, ${\tau}P=10ns$) and a femtosecond laser (${\lambda}=1027nm$, ${\tau}P=380fs$) were installed on an optical system for the micromachining test. The ablation characteristics of the pure $I_{ph}$ and CNT/$I_{ph}$ composites, such as thermal effect and ablation depth, were investigated using FE-SEM and a confocal microscope device. Laser machining results for the two mating materials showed improved performances: CNT/$I_{ph}$ composites showed good surface morphology of hole drilling without a melting zone due to the composites' high thermal properties; also, the ablated depth of CNT/$I_{ph}$ was higher than that of pure $I_{ph}$.

• 제어로봇시스템학회:학술대회논문집
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• 1998.10a
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• pp.346-351
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• 1998

Cutting process has been automated due to progress of CNC and CAD/CAM, but polishing process has been only depended on experiential knowledge of expert. Polishing work for a curved surface die demands simple and repetitive operations but requires much time for its high precision. Therefore it is operated in the handiwork by skilled worker. However the workers intend to avoid gradually polishing work because of the poor environments such as dust and noise. In order to reduce the polishing time and solve the problem of shortage of skilled workers, it has been done some research for an automation of polishing. To automate the polishing process, a 2 axes polishing robot which is attached to a 3 axes machining center has been developed by our previous research. This automatic polishing robot is able to keep the polishing tool normal on the curved surface of die. Therefore its performance of polishing is improved because of always keeping the tool normal on the surface. In this paper, the smaller sized polishing robot is developed to improve polishing performance. And the controller for 2 axes polishing robot is developed. The controller is composed of TMS320C31 with high speed which is 40-ns instruction cycle time, RAM memory with 64K words, digital input with 64 bits, digital output with 32 bits, and D/A converter with 4 channels, which is 12 bits resolution. To evaluate polishing performance of this developed robot, polishing experiment for shadow mask was carried out.

• Journal of Pharmacopuncture
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• v.3 no.2
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• pp.41-54
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• 2000

This study was undertaken to determine if Plantaginis Semen Herbal Acupuncture(PSA) has a protective effect against glycerol-induced acute renal failure in rats. Rats were dehydrated for 24hr and then injected with 8 ml/kg of $50\%$ glycerol, one-half of dose in each hindlimb muscle. In experiments for PSA effect, rats received 0.1 ml of PSA extraction in both sides of corresponding Shenso($BL_{23}$) of human body for 3 days after injection of glycerol. The experimental group were di vided into the Normal group, the Control group, the PSA group. Glycerol injection decreased glomerular filtration rate and increased urine volume, serum creatinine, BUN level and fractional excretion of glucose, $Na^+$, $K^+$ and $CI^-$. These result show that glycerol injection result in acute renal failure. PSA significantly increased glomerular filtration rate and significantly decreased serum creatinine, BUN level and fractional excretion of glucose, $Na^+$ and $CI^-$ as compared Control group. This suggests that PSA could be used in prevention and treatment of acute renalfailure. However, the precise mechanisms of PSA protection remain to be determined.