• Title/Summary/Keyword: Normal values

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Effects of Reduced Glutathione and Ginseng Extract on Non-Protein Sulfhydryl, and Non-Protein Disulfide of Mouse Liver and Blood Following Whole Body X-Irradiation (Reduced glutathione 및 인삼추출액(人蔘抽出液)이 X-선전신조사(線全身照射)를 입은 마우스 간조직(肝組織) 및 혈중(血中) NP-SH 및 NP-SS에 미치는 영향(影響))

  • Oh, Jang-Suk
    • The Korean Journal of Physiology
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    • v.6 no.2
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    • pp.57-63
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    • 1972
  • In an attempt to better understand the radioprotective effect of reduced glutathione(GSH), and to observe a possible radioprotective effect of Ginseng extract, whole body X-irradiation of 1,200 r was administered to the mouse either independently or immediately following the injection of GSH or Ginseng extract to the mouse intraperitoneally. The non-protein sulfhydryl (NP-SH) and non-protein disulfide (NP-SS) levels of the liver, and NP-SH level of NP-SH of the blood of the mouse were measured at 30, 60 and 120 minutes, and results were compared with the normal. The results thus obtained are summarized as follows; 1) The normal values of NP-SH and NP-SS of the mouse liver were $5.90{\pm}0.46\;{\mu}\;mol/gm\;wet\;wt.,\;and\;3.02{\pm}0.42\;{\mu}\;mol/ml$ wet wt., respectively, and the normal value of NP-SH of NP-SH of the mouse blood was $3.98{\pm}1.29\;{\mu}\;mol/ml$ 2) The injection of both GSH and Ginseng extract produced the highest values of NP-SH in the liver at 30 minutes, but a gradual decrease to the normal was observed thereafter. When X-irradiation alone was applied, the liver NP-SH value was lower than the normal at 60 minutes post-irradiation and thereafter. When Ginseng extract was injected immediately prior to X-irradiation, the liver NP-SH was lower than the normal throughout the experiment with the lowest value at 60 minutes. However, the combination of GSH and X-irradiation produced higher than the normal values throughout the entire experiment. 3) The liver NP-SS value was most significantly elevated at 30 minutes after the injection of GSH, hut the recovery to the normal was observed thereafter. The injection of Ginseng extract produced slightly higher liver NP-SS values at 30 and 60 minutes, but the value at 120 minutes was similar to the normal. The single application of X-irradiation resulted in the lower then normal liver NP-SS values throughout the entire experiment. When GSH was injected price to X-irradiation, the liver NP-SS values were higher than the normal at 30 and 60 minutes followed b the recovery to the normal at 120 minutes. The combination of Ginseng extract and X-irradiation showed generally lower liver NP-SS values throughout the experiment. 4) The blood NP-SH showed the higher than the normal values in all the experimental groups except when GSH was injected prior to X-irradiation alone produced e significantly elevated blood NP-SS value at 30 minutes post-irradiation.

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A Study on the Blood Chemical Values of the Infertile Dairy Cattle Raised in the High-land (고지사육 번식장해 유우의 혈액화학치에 관한 연구)

  • Kim Doo;Goh Gwang-Du;Park Choon-Keun;Kim Hyun-Ki
    • Journal of Veterinary Clinics
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    • v.6 no.1
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    • pp.193-198
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    • 1989
  • This study was performed to determine the blood chemical values of the 50 normal multiparous and 98 infertile dairy cattle which were raised in the high-land of kangweon area. The results obtained in this study were summerized as follow. 1. The mean values of the serum total protein, albumin and A/G ratio the infertile dairy cattle were lower than those of the normal multiparous dairy cattle. 2. The mean value of the serum globulin of the infertile dairy cattle was higher than that of the normal multiparous dairy cattle. 3. The mean values of the serum total cholesterol, glucose, calcium and inorganic phosphorus of the infertile dairy cattle were lower than those of the normal multiparous dairy cattle. 4. The mean value of the SGOT of the Infertile dairy cattle was higher than that of the normal multiparous dairy cattle.

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A Study on Fasting Serum Gastrin level in Normal Subjects and Various Gastric Diseases by Radioimmunoassay (각종(各種) 위질환(胃疾患)에 있어서의 혈청(血淸) gastrin 치(値)에 관(關)한 임상적(臨床的) 연구(硏究))

  • Lee, Yong-Duck;Lee, Heon-Sil;Park, Seung-Uk;Park, Sung-Hwi;Lee, Chong-Suk;Lee, Hak-Choong
    • The Korean Journal of Nuclear Medicine
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    • v.15 no.2
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    • pp.67-74
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    • 1981
  • The fasting serum gastrin levels were measured by radioimmunoassay in 32 normal healthy subjects without recognized gastrointestinal symptoms and 90 patients with various gastric diseases, who were visited or admitted to National Medical Center from February to June, 1981. The following results were obtained; 1) The fasting mean serum gastrin level in normal subjects was $55.9{\pm}26.3pg/ml$, and there was no difference between male and female. 2) The gastrin levels in gastric and duodenal ulcer were $85.0{\pm}28.4$ and $76.0{\pm}43.0pg/ml$ respectively, and it's values were elevated as compared with normal subjects. In gastric ulcer, the gastrin level was elevated than that of duodenal ulcer, but no significant difference in each other. 3) The gastrin level in stomach cancer was $89.5{\pm}42.2pg/ml$, and it's values were markedly elevated as compared with values in normal subjects. 4) The gastrin level in gastritis was $73.4{\pm}37.4pg/ml$, and it's values were elevated as compared with values in normal subjects. 5) The gastrin level in post-gastrectomy state was $50.3{\pm}16.3pg/ml$, and it's values were slightly decreased as compared with values in normal subjects.

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Objectification of the Qi Blood Yin Yang Deficiency Pattern by Using a Facial Color Analysis

  • Park, Hye Bin;Yu, Junsang;Lee, Hyun Sook
    • Journal of Pharmacopuncture
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    • v.20 no.2
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    • pp.100-106
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    • 2017
  • Objectives: This study aimed to assess a Qi Blood Yin Yang evaluation method systematically and objectively and to identify the correlation between the Qi Blood Yin Yang deficiency pattern (QBYYDP) and facial color. Methods: Thirty-seven participants (17 males, 20 females) were enrolled in this study. Twenty-four (10 males, 14 females) had ages from 40 to over 60, and 13 (7 males and 6 females) were in their twenties. After sufficient rest, facial images were taken with a camera. Based on the results from a questionnaire survey, we divided the participants into five groups: the normal and the Qi-, Blood-, Yin-, and Yang-deficient groups, after which the relationships between the L, 'a', and 'b' values in the Lab color system and the characteristics of the participants in each of the deficient groups were elucidated using a facial color analysis program. Results: The color analysis for Qi-deficient (QD) participants revealed that the L value was fairly decreased in comparison with the normal participants, but the 'a' and 'b' values were almost the same. A comparison between the normal and the Yang-deficient (YaD) groups revealed that the L values were somewhat lower compared to the normal group, but the 'a' and 'b' values were not statistically different. For the Yin-deficient (YiD) group, the L value was slightly lower compared to the normal group, but the 'a' and 'b' values were almost the same and the R values were slightly increased. For the Blood-deficient (BD) group, the L values were slightly increased compared to the normal group, but the 'a' and 'b' values were decreased slightly. Conclusion: This study obtained objective, reliable data for judging the QBYYDP by using facial images and a color analysis program. However, further study with at least 10 or more subjects in each of the deficient groups is necessary to confirm our findings.

Study on the Erythrocyte Zinc Proctoporphyrin and ZPP/Heme Ratio in Normal Korean (한국인 적혈구 Zinc Protoporphyrin 및 ZPP/Heme Ratio에 관한 연구)

  • 채범석
    • Journal of Nutrition and Health
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    • v.25 no.7
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    • pp.608-616
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    • 1992
  • Using the hematofluiorometer normal values of the erythrocyte zinc protoporphyrin(ZPP) and ZPP/Heme ratio were measured in 312 males and 163 females aged from 6 month to 73 years old and compared with those of anemic persons. The mean$\pm$SD values of ZPP of normal Koreans were 28.5$\pm$6.4($\mu\textrm{g}$/dl) in males and 3.18$\pm$7.7 in females. the mean$\pm$SD of ZPP/Heme ratio were 49.5$\pm$12.3($\mu$mol/mol heme) in males and 62.0$\pm$15.8 in females. The difference in the mean ZPP and ZPP/Heme ratio values between male and female subjects were statistically signficant(p<0.0001) In male subjects the mean ZPP and ZPP/Heme ratio of the age groups less than 15 years old were higher than adult groups and the difference between age groups was significant(p<0.005 and p<0.0001 respecti-vely) The normal upper limit of the mean$\pm$2SD in normal male and female subjects were 41.3 and 47.2 for ZPP and 74.1 and 93.6 for ZPP/Heme ratio respectively. The mean values of ZPP and ZPP/Heme ratio measured in the anemic persons were higher than those of normal subjects and did not show any significant difference by the sex and age groups except in 6-14 years male groups. The test specificity(positivity) analyzed in the anemic persons by the cut-off values calculated from the normal data were 50.6% for ZPP and 73.0% for ZPP/Heme ratio. The correlation analysis between blood hemoglobin and erythrocyte ZPP or ZPP/Heme ratio in the total 801 normal and anemic subjects showed that there are very high logarithmic correlation between the hemoglobin levels and ZPP/Heme ratio (r=-0.8339) and high correla-tion between the hemoglobin levels and ZPP concentrations(r=-0.6372) These results suggested that the measurement of the erythrocyte ZPP and ZPP/Heme ratio with the hematofluorometer can be a usuful screening method for iron deficiency anermin because they provide a reliable immediate results with a small amount of sample and are relatively simple and inexpensive.

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The Clinical Efficacy of Pasaekhwalhyeol-Tang on Acute Headache of an Acute Cerebral Infarct Patient (급성기 뇌경색 환자의 두통에 대한 파한활혈탕(破寒滑血湯)의 임상적 효능)

  • Shim, Yun-Seub;Seong, Ki-Won
    • The Journal of Internal Korean Medicine
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    • v.25 no.4
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    • pp.318-323
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    • 2004
  • Objectives : The purpose of this clinical study is to evaluate the clinical efficacy of Pasaekhwalhyeol-Tang on acute headache from acute cerebral infarct. Methods : Pasaekhwalhyeol-Tang was prescribed to 15 acute cerebral infarct patients for two weeks. Symptoms were checked and VAS(Visual Analog Scale) scores were kept every week. Results : After prescription of Pasaekhwalhyeol-Tang, VAS scores on headache and accompanying symptoms decreased. No significant changes were shown in laboratory findings. As for the laboratory findings, ALT showed an upward tendency within a week and increased over normal values in two cases(13%). But two weeks later, ALT decreased within normal values. And the mean serum level was within normal values and the other hepatic enzymes did not increase over normal values in either week nor week 2. Conclusions : Results suggest that Pasaekhwalhyeol-Tang is effective in reducing the severity of acute headache from acute cerebral infarct.

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Studies on Hematologic Values and Blood Chemistry Values of Normal Jindo Dogs - 1. Hematologic Values for Jindo Dogs (진도견의 혈액상 및 혈액화학치에 관한 연구 - 제1보 진도견의 혈액상)

  • Park Nam Yong
    • Journal of the korean veterinary medical association
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    • v.16 no.3
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    • pp.137-141
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    • 1980
  • Hematologic values were determined in cephalic vein blood samples obtained from 20 males and 37 females adult normal Jindo dogs. 1. The mean values of red blood cell count, hemoglobin value and packed cell volume were $7.29{\pm}2.27{\times}10^6/{\mu}

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A Study on the Correlation between Pulse Energy and Sasang Constitutional Syndromes (맥 Energy와 사상체질병증의 연계 연구)

  • Kim, Dal-Rae;Kim, Sun-Hyung
    • The Journal of Korean Medicine
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    • v.30 no.1
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    • pp.26-39
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    • 2009
  • Objectives: Pulse energy values recorded with an add-pres sure-type pulse apparatus were correlated with Sasang constitutional syndromes in order to match pulse energy values with Sasang prescriptions. Methods: The pulse energy values were measured with Daeyo Pulse Apparatus at the Gwan pulse point of both wrists. Prescriptions were divided into two major categories of interior syndromes or exterior syndromes, and categorized according to major component herbs specific to each of the four Sasang constitutions, and the relationship between the pulse energy and each groups divided by their prescription was studied. Results: About 10% of all people had nonmal pulse energy values. 10% had values over normal range, and $70\sim80%$ had lower values than normal. The normal range of pulse energy was regarded as being between 450 and 700. Conclusions: 1. For patients of the Soeum constitution, prescriptions without Panax ginseng is suitable for patients with high pulse energy, and prescriptions containing Panax ginseng are suitable for patients who have lower pulse energy. 2. All prescriptions for the Soyang constitution containing Rehmannia radix preparata or Comus officinalis are suitable for patients who have lower pulse energy, and prescriptions containing Rehmannia radix or Gypsum fibrosum are applicable to patients with pulse energy values higher than normal. 3. Most prescriptions for the Taeum constitution containing Semen coicis or Semen castaneae are suitable for patients with lower pulse energy, and prescriptions containing Radix puerariae or Radix et rhizoma rhei can be prescribed for patients who have lower pulse energy levels. 4. The Taeyang constitutional prescription Ogapijangcuck-tang is suitable for patients who have higher pulse energy levels and Mihudeungsikjang-tang is better for patients with lower than normal pulse values. As described above, the pulse energy level of each patient can be matched with a specific Sasang constitutional prescription. If this relationship is taken into consideration with other conventional symptoms, it can be helpful in diagnosis, improving efficacy of treatment, and be used as objective evidence.

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Uncertainty of Agrometeorological Advisories Caused by the Spatiotemporally Averaged Climate References (시공간평균 기준기후에 기인한 농업기상특보의 불확실성)

  • Kim, Dae-jun;Kim, Jin-Hee;Kim, Soo-Ock
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.19 no.3
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    • pp.120-129
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    • 2017
  • Agrometeorological advisories for farms and orchards are issued when daily weather exceeds a predefined range of the local reference climate, which is a long-term average of daily weather for the location. The reference climate at local scales is prepared by various simplification methods, resulting in uncertainty in the agrometeorological advisories. We restored daily weather data for the 1981-2010 period and analyzed the differences in prediction results of weather risk by comparing with the temporal and spatial simplified normal climate values. For this purpose, we selected the agricultural drought index (ADI) among various disaster related indices because ADI requires many kinds of weather data to calculate it. Ten rural counties within the Seomjin River Basin were selected for this study. The normal value of 'temporal simplification' was calculated by using the daily average value for 30 years (1981-2010). The normal value of 'spatial simplification' is the zonal average of the temporally simplified normal values falling within a standard watershed. For residual moisture index, temporal simplification normal values were overestimated, whereas spatial simplification normal values were underestimated in comparison with non-simplified normal values. The ADI's calculated from January to July 2017 showed a significant deviation in terms of the extent of drought depending on the normal values used. Through this study, we confirmed that the result of weather risk calculation using normal climatic values from 'simplified' methods can affect reliability of the agrometeorological advisories.

Adhesion of clay to metal surface; Normal and tangential measurement

  • Basmenj, Amir Khabbazi;Ghafoori, Mohammad;Cheshomi, Akbar;Azandariani, Younes Karami
    • Geomechanics and Engineering
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    • v.10 no.2
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    • pp.125-135
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    • 2016
  • Adhesion in geotechnical engineering is the interaction between cohesive soil and a solid surface which can cause clogging in mechanized tunnelling through clayey formations. Normal piston pull out and modified direct shear tests were performed on clayey soil samples to determine which type of adhesion stress, normal or tangential, could be most effectively measured. Measured values for normal adhesion ranged from 0.9 to 18 kPa. The range of tangential adhesion was 2.4 to 10 kPa. The results indicate normal adhesion results were more accurate than those for the modified direct shear test that measure tangential adhesion. Direct shear test on identical samples did not show any correlation between measured cohesion and normal adhesion values. Normal adhesion values have shown significantly meaningful variation with consistency index and so are compatible with the base of field clogging assessment criteria. But tangential adhesion and cohesion were not compatible with these assessment criteria.