• Journal of Radiation Protection and Research
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• v.36 no.1
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• pp.44-51
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• 2011

Activation foil-based Bonner sphere spheres are used to obtain neutron energy spectra of nuclear power plants or accelerator-produced neutrons. The position and the foil mass dependence of response functions should be studied carefully before measurement of Bonner spheres. This study showed that the normal incidence to the foil surface made a large shift of responses while parallel and isotropic incidence made no position dependence. The correlation between foil mass and response was not linear. Therefore, the response functions of activation-foil based Bonner spheres should be calculated for every different foil mass and the direction of Bonner spheres for parallel incidence will be preferred for radioactive neutron source or accelerator target produced neutrons.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.8
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• pp.4847-4851
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• 2013

Objectives: To evaluate accuracy of FDG-PET CT in prediction of persistent disease in head and neck cancer cases and to determine prognostic value of metabolic tumor response. Materials and Methods: Between 2009 and 2011, 46 patients with squamous cell carcinoma of head and neck receiving PET-CT were treated with definitive radiotherapy, with or without chemotherapy. There were 29 nasopharyngeal, 11 hypopharyngeal, 3 oropharyngeal and 3 laryngeal cancer patients, with a median age of 50.5 years (range 16-84), 32 males and 14 females. All patients were evaluated with PET-CT median 3-5 months (2.4-9.4) after completion of radiotherapy. Results: After a median 20 months of follow up, complete metabolic response was observed in 63% of patients. Suspicious residual uptake was present in 10.9% and residual metabolic uptake in 26.0% of patients. The overall sensitivity, specificity, positive predictive value and negative predictive value of FDG-PET-CT for detection of residual disease was 91% and 81%, 64% and 96% respectively. Two year LRC was 95% in complete responders while it was 34% in non-complete responders. Conclusions: FDG PET CT is a valuable tool for assessment of treatment response, especially in patients at high risk of local recurrence, and also as an indicator of prognosis. Definitely more precise criteria are required for assessment of response, there being no clear cut uptake value indicating residual disease. Futhermore, repair processes of normal tissue may consume glucose which appear as increased uptake in control FDG PET CT.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.831-835
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• 2014

Background: Predictor factors determining complete response to treatment are still not clearly defined. We aimed to evaluate clinicopathological features, risk factors, treatment responses, and survival analysis of patient with advanced nonseminomatous GCTs (NSGCTs). Materials and Methods: Between November 1999 and September 2011, 140 patients with stage II and III NSGCTs were referred to our institutions and 125 patients with complete clinical data were included in this retrospective study. Four cycles of BEP regimen were applied as a first-line treatment. Salvage chemotherapy and/or high-dose chemotherapy (HDCT) with autologous stem cell transplantation were given in patients who progressed after BEP chemotherapy. Post-chemotherapy surgery was performed in selected patients with incomplete radiographic response and normal tumor markers. Results: The median age was 28 years. For the good, intermediate and poor risk groups, compete response rates (CRR) were, 84.6%, 67.9% and 59.4%, respectively. Extragonadal tumors, stage 3 disease, intermediate and poor risk factors, rete testis invasion were associated with worse outcomes. There were 32 patients (25.6%) with non-CR who were treated with salvage treatment. Thirty-one patients died from GCTs and 94% of them had stage III disease. Conclusions: Even though response rates are high, some patients with GCTs still need salvage treatment and cure cannot be achieved. Non-complete response to platinium-based first-line treatment is a negative prognostic factor. Our study confirmed the need for a prognostic and predictive model and more effective salvage approaches.

• Fire Science and Engineering
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• v.32 no.5
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• pp.40-45
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• 2018

This paper is an analysis of the influence of ceiling air conditioner airflow on fire detector response. In order to analyze the response characteristics of fire detector while forming air flow of a ceiling-type air conditioner, fire tests were carried out in accordance with ISO standard. This experiment was carried out in a fire test site of 10 m (width) ${\times}$ 7 m (length) ${\times}$ 4 m (height). As a result of the experiment, the response of fire detector shows a normal pattern that is delayed as the distance from the fire source is increased in the absence of the air conditioner, but it is confirmed that the pattern is not maintained in the strong air flow. When the air flow of air conditioner was strong, the response time was increased by 121% in the smoke detector and by 39% in the heat detector. In the case of ceiling type air conditioners, it is considered that the number of fire detectors should be increased, or a detector with high sensitivity should be installed for early detection of fire.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.7 no.1
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• pp.45-50
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• 2013

Recently, a method for detecting animal tinnitus objectively, gap prepulse inhibition of acoustic startling (GPIAS) were reported. However, the GPIAS method is difficult to be directly applied to human tinnitus research because measuring repeatedly startling responses evoked by more than 110 dB SPL acoustic stimuli for human is not easy. In this paper, the auditory late latency response (ALLR) measurement system which can measure conveniently evoked potentials involving the information about the brain cortical activity related with auditory psychologic phenomena such as a tinnitus has been implemented. By using the implemented system, 8 persons with normal hearing sense have been experimented to measure N1-P2 amplitudes of ALLRs evoked by gap prepulse based acoustic stimuli. Through the experimental results, the prepulse inhibitions of all the participants' N1-P2 responses have been observed and their characteristics were evaluated. And it is verified that our implemented system can be utilized as a device for researching and evaluating the objective tinnitus detection method in the future study.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1977.06a
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• pp.4.1-4
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• 1977

A variety of diagnostic means for evaluating the hearing ability of neonates and infants have been studied so far, and some physical responses of neonates and infants to loud sound is still of much value. The author studied some normal responses of 100 neonates (male 54, female 46) in our neonatal room from Jan, 1977 to April, 1977. We took 90dB pure tone at 3, 000Hz by Beltone Audiometer model l0D (ANSI 1969) for a stimulus. The results are as follows: 1. The range of the examinees' age is between 2 and 3.5 hours (average 2.4 hours), and auropalpebral response is in 39% (eyelid blinking 10%, eyelid widening 29%), Moro reflex in 35%, sucking response in 14%, cessation of movement in 6%, head turning response in 2%, and no response in 4%. 2. The duration of response is between 2 and 5 Seconds (average 3.3 seconds).

• Steel and Composite Structures
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• v.12 no.4
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• pp.353-379
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• 2012

The accuracy of the 30% and SRSS rules, commonly used to estimate the combined response of structures, and some related issues, are studied. For complex systems and earthquake loading, the principal components give the maximum seismic response. Both rules underestimate the axial load by about 10% and the COV of the underestimation is about 20%. Both rules overestimate the base shear by about 10%. The uncertainty in the estimation is much larger for axial load than for base shear, and, for axial load, it is much larger for inelastic than for elastic behavior. The effect of individual components may be highly correlated, not only for normal components, but also for totally uncorrelated components. The rules are not always inaccurate for large values of correlation coefficients of the individual effects, and small values of such coefficients are not always related to an accurate estimation of the response. Only for perfectly uncorrelated harmonic excitations and elastic analysis of SDOF systems, the individual effects of the components are uncorrelated and the rules accurately estimate the combined response. In the general case, the level of underestimation or overestimation depends on the degree of correlation of the components, the type of structural system, the response parameter, the location of the structural member and the level of structural deformation. The codes should be more specific regarding the application of these rules. If the percentage rule is used for MDOF systems and earthquake loading, at least a value of 45% should be used for the combination factor.

• Journal of Domestic Journal Test
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• v.11 no.2
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• pp.221-227
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• 2023

− A rotordynamic system consists of components that undergo rotational motion. These components include shafts, impellers, thrust collars, and components that support rotation, such as bearings and seals. The motion of this type of rotating system can be modeled as two-dimensional motion and, accordingly, the equa- tion of motion for the rotordynamic system can be represented using complex coordinates. The directional fre- quency response function (dFRF) can be derived from this complex coordinate system and used as an effective analytical tool for rotating machinery. However, the dFRF is not widely used in the field because most pre- vious studies and commercial software are based on real coordinate systems. The objective of the current study is to introduce the dFRF and show that it can be an effective tool in rotordynamic analysis. In this study, the normal frequency response function (nFRF) and dFRF are compared under rotordynamic analysis for isotropic and unisotropic rotors. Results show that in the nFRF, the magnitude of the response is the same for both pos- itive and negative frequencies, and the response is similar under all modes. Consequently, the severity of the mode cannot be identified. However, in the dFRF, the forward and backward modes are clearly distinguishable in the frequency domain of the isotropic rotor, and the severity of the mode can be identified for the uniso- tropic rotor.

• Korean Journal of Psychosomatic Medicine
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• v.10 no.1
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• pp.18-26
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• 2002

Objectives : The object of this study was to investigate the relationship between coping strategies and perceived stress or pain discomfort in patients with chronic low back pain. 80 patients with chronic low back pain and 100 normal controls participated in this study. Methods: Global assessment of recent stress (GARS) scale and Stress Response Inventory (SRI) were used to measure perception for stressors and stress responses. Coping scale and pain discomfort scale were used to measure coping strategies and pain perception. Results : Scores of perceived stress related to work or job, interpersonal relationship, changes in relationship, sickness or illness and the total scores on the GARS scale were significantly higher in those with chronic low back pain than normal controls. Scores of the SRI fatigue subscale scored significantly higher in those with chronic low back pain than normal controls. No significant difference was found on total scores of the pain discomfort scale between those with chronic low back pain and normal controls. The patients with chronic low back pain scored significantly higher on planful problem solving and positive reappraisal than normal controls. In the patient group, pain perception had significant positive correlations with total scores of the SRI and scores of stress perception related to illness or injury. The extent of escape-avoidance showed significant negative correlations with age, whereas the extent of distancing or escape-avoidance had significant negative correlations with the level of education. Significant difference was also found in accepting responsibilities between male subjects and females. However, no significant correlations were found between coping strategies and perceived stressors, stress responses or pain perception. Conclusion : The results suggest that patients with chronic low back pain were more likely to use more active coping strategies than normal controls, though the former had more perception for stressors than the latter. It was also found that coping strategies used by the patients were associated with sociodemographic factors, but that they were not associated with perceived stressors, stress responses or pain perception.

• Physical Therapy Korea
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• v.12 no.3
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• pp.56-66
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• 2005

The purposes of this study were to test that complex motor training enhance motor function significantly, to test change in cerebellum, and to test the synaptic plasticity into the immunohistochemistry response of synaptophysin. Using an animal model of fetal alcohol syndrome - which equates peak blood alcohol concentrations across developmental period - the effects of alcohol on body weight during periods were examined. The effect of complex motor training on motor function and synaptic plasticity of rat exposed alcohol on postnatal days 4 through 10 were studied. Newborn rats were assigned to one of two groups: (1) normal group (NG), via artificial rearing to milk formula and (2) alcohol groups (AG), via 4.5 g/kg/day of ethanol in a milk solution. After completion of the treatments, the pups were fostered back to lactating dams, where they were raised in standard cages (two-and three animals per cage) until they were postnatal 48 days. Rats from alcohol group of postnatal treatment then spent 10 days in one of two groups: Alcohol-experimental group was had got complex motor training (learning traverse a set of 6 elevated obstacles) for 4 weeks. The alcohol-control group was not trained. Before consider replacing with "the experiment/study", (avoid using "got" in writing) the rats were examined during four behavioral tests and their body weights were measured, then their coronal sections were processed in rabbit polyclonal antibody synaptophysin. The synaptophysin expression in the cerebellar cortex was investigated using a light microscope. The results of this study were as follows: 1. The alcohol groups contained significantly higher alcohol concentrations than the normal group. 2. The alcohol groups had significantly lower body weights than the normal group. 3. In alcohol groups performed significantly lower than the normal group on the motor behavioral test. 4. In alcohol-control group showed significantly decreased immunohistochemistric response of the synaptophysin in the cerebellar cortex compared to the nomal group. These results suggest that improved motor function induced by complex motor training after postnatal exposure is associated with dynamically altered expression of synaptophysin in cerebellar cortex and that is related with synaptic plasticity. Also, these data can potentially serve as a model for therapeutic intervention.