• Title/Summary/Keyword: Normal movement

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Comparison Studies of SPECT Dopamine Transporter Imaging and Noninvasive Quantification using [Tc-99m]TRODAT-1 and [I-123]IPT ([Tc-99m]TRODAT-1과 [I-123]IPT SPECT를 이용한 도파민 운반체의 영상화 및 정량분석 비교)

  • Kim, Hee-Joung;Bong, Jung-Kyun;Lee, Hee Kyung
    • The Korean Journal of Nuclear Medicine
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    • v.32 no.1
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    • pp.10-19
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    • 1998
  • The SPECT radiopharmaceuticals labeled with I-123 for dopamine transporter imaging have been used to measure dopamine transporters in patients with movement disorders. However, a cyclotron produced I-123 limits its availiability and ease of use as a radioisotope to be labeled with pharmaceuticals in routine clinical diagnostic procedures. Recently, new radiophannaceuticals for Tc-99m which has optimal characteristic for SPECT imaging have been developed to overcome the limits of using I-123. The purpose of this study was to compare the quality of [Tc-99m]TRODAT-1 with [I-123]IPT SPECT data and then to evaluate the usefulness of [Tc-99m]TRODAT-1 SPECT by using three noninvasive simplified quantitative methods. TRODAT-1 labeled with Tc-99m($15.93{\pm}0.82mCi$) and IPT labeled with I-123($6.60{\pm}0.11mCi$) were injected into five normal controls. Dynamic [Tc-99m]TRODAT-1 SPECT scans of brain were performed for 10 minutes each over 180 minnutes, and for 20 minutes at 4 hrs and 5 hrs. [I-123]IPT SPECT scans were performed for 5 minutes each over 120 minutes. Time activity curves were generated for the left basal ganglia(LBG), right basal ganglia(RBG), and occipital cortex(OCC). Dopamine transporter parameters were ohtained using (BG-OCC)/OCC, graphical method($R_V$), and area ratio method($R_A$). TRODAT-1 and IPT SPECT imaging showed high uptake at the level of the basal ganglia. (BG-OCC)/OCC ratios for TRODAT-1 and IPT were $0.80{\pm}0.14$, and $3.22{\pm}0.81$, $R_Vs$ were $0.62{\pm}0.12$, and $2.30{\pm}0.35$, and $R_As$ were $0.37{\pm}0.08$ and $1.73{\pm}0.31$, respectively. In conclusion, further improvement of [Tc-99m]TRODAT-1 imaging characteristics may be required to estimate the dopamine transporter concentrations in human brains although it shows clear BG localization.

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Paleomagnetic Study on Cretaceous Rocks in Haenam Area (해남지역의 백악기 암석에 대한 고지자기 연구)

  • 임무택;이윤수;강희철;김주용;박인화
    • Economic and Environmental Geology
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    • v.34 no.1
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    • pp.119-131
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    • 2001
  • A mean characteristic remanent magnetization was obtained for the first time in Korea from volcanic and pyroclastic sedimentary rocks distributed in Haenam Area, located in southwestern part of the Korean Peninsula. The age of the prevailing rocks in this area belongs mostly to Late Cretaceous, with a few exceptions of Early Cretaceous, mainly based on K/Ar whole rock age dating. Characteristic remanent magnetizations of these have both normal and reverse polarities with antipodal direction, which were interpreted to be the primary remanent magnetizations obtained by the ambient Earth's magnetic field at the time of formation of the concerned rocks. The source magnetic minerals of the remanent magnetization has been identified as magnetite. The mean direction of characteristic remanent magnetization obtained from the Late Cretaceous rocks in this study is Dm/Im=21.4 supper(o)/57.1 supper(o) (${\alpha}_{95}=13.4^{\circ}$, k=350.0). The paleomagnetic pole position calculated from this result for the Late Cretaceous, is $72.5^{\circ}N/199.9^{\circ}E$ (dp/dm= $14.2^{\circ}/19.5^{\circ}E$), which matches well with those of 80 Ma ($76.2^{\circ}N/198.9^{\circ}E$) and 90 Ma ($76.2^{\circ}N/200.1^{\circ}E$) of the Eurasian Continent's APWP (Apparent Polar Wander Path). This result strongly indicates that the studied area, belonging to the Eurasian Continent, have suffered very little geotectonic movement after the Late Cretaceous. The deflection of declination of remanence from Early Cretaceous rocks in the study area may indicate that the micro-block was counterclockwisely rotated with vertical axis between the late of Early Cretaceous and the early of Late Cretaceous.

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TREATMENT OF ECTOPICALLY ERUPTING FIRST PERMANENT MOLAR IN CHRONIC MYELOGENOUS LEUKEMIA (전신 질환을 동반한 환아에서 나타난 제1대구치 이소맹출의 처치)

  • Kim, Hyun-Jung;Kim, Min-Jeong;Noh, Hong-Seok;Kim, Shin;Jeong, Tae-Sung
    • The Journal of Korea Assosiation for Disability and Oral Health
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    • v.7 no.1
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    • pp.33-37
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    • 2011
  • The ectopic eruption is defined as abnormal eruption which gives to displacement of the teeth and abnormal root resorption of adjacent teeth. The prevalence of ectopic eruption is reported to vary 2~6%, most of them are in the maxilla. Etiologic factors include narrow maxilla, large maxillary teeth, inclined eruption path of the first molar, retruded position of the maxilla and hereditary factor. Irreversible ectopic eruption where the second primary molar is lost often causes mesial tipping and rotation of the permanent molar, unfavorable occlusion and space deficiency for the second premolar. Ectopically erupted teeth should be treated early to maintain normal development of the dentition, harmony of facial growth and occlusal support. The method of the treatment are classified as follows : appliances that is positioned at the contact point for unlocking and the distal movement, fixed appliance that is connected to more than one tooth, and occlusion guiding method after disking or extraction of the second deciduous molar. A case report of a patient with bilaterally ectopic eruption of maxilla and mandible first permanent molar was present. Also, the patient who had experienced the chronic myelogenous leukemia, show various dental developmental complications. The ectopic eruption was treated with a Halterman appliance that was a effective way of correcting of ectopic eruption of the permanent first molar.

AN EXPERIMENTAL STUDY ON THE TISSUE RESPONSE OF THE TEMPOROMANDIBULAR JOINT IN UNILATERAL MANDIBULAR EDENTULISM (하악편측치아의 결손에 따른 악관절의 조직반응에 대한 연구)

  • Paik, Hyee-Seon;Kim, Yung-Soo
    • The Journal of Korean Academy of Prosthodontics
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    • v.29 no.2
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    • pp.285-294
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    • 1991
  • The human temporomandibular joint as a ginglymoarthrodial one has much in common with the other synovial joints of the body, but it does possess an unique charachteristic in that it must accomodate the various occlusal relations of dentition during an end point of closure. For that reason, the movement of the condyle in the temporomandibular joint is susceptible to influences from the nature of occlusion. Undue loading to the temporomandibular joint can be applied on the occasion of premature contacts in centric relation, balancing side interferences, change of occlusal surfaces due to excessive attrition, loss of tooth. Such occlusal disharmonies in association with the systemic and emotional factors may give rise to the temporomandibular disorder. On the other hand, the changes of occlusal patterns in the growing body can also have an effect on the growth of the temporomandibular joint through the alterations of functional stresses. The purpose of this study was to observe histopathologic response of the temporomandibular joint in unilateral chewing on one side exclusively for 10 months. Three dogs showing normal masticatory function were chosen. One dog aged about 12 months was for control, two dogs for experimental specimens were about 12 and 18 months old respectively. For chewing on the left side only, unilateral lower right premolar and molar were extracted in two experimental specimens. And then three dogs were sacrificed 10 months later. Frontal histologic sectioning of joints were done for the observation of the effects of one-side chewing. 24 specimens from three dogs were obtained and fixed in 10% formalin and routinly processed with H-E staining for histologic examination. The light microscopic findings were interpretated as follows: 1. Experimental specimen 1 aged about 22 months: In comparison with control and right non-chewing side, the proliferative and hypertrophic zone were increased at the mesial and lateral part of left chewing side condyle. There was no change of the articular tissue of temporal bone. 2. Experimental specimen 2 aged about 28 months: The articular tissues of adult joint were observed. The differences between the chewing and non-chewing side were not seen in the articular tissues of condyle and temporal bone.

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ERUPTION GUIDANCE FOR TOOTH GERM OF PREMOLAR DISPLACED BY INFRAOCCLUDED UPPER DECIDUOUS MOLAR (저위교합된 상악 유구치에 의해 변위된 소구치 치배의 맹출유도)

  • Jung, Jung-Hwa;Kim, Young-Jin;Kim, Hyun-Jung;Nam, Soon-Hyeun
    • Journal of the korean academy of Pediatric Dentistry
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    • v.39 no.4
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    • pp.390-396
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    • 2012
  • Infraocclusion is defined as tooth whose relative occlusal movement was blocked during the period of active eruption due to ankylosis and so on. Then infraoccluded tooth remains under the occlusal plane composed by adjacent structures showing normal eruption patterns. Untreated infraocclusion may cause: prolonged retention of infraoccluded teeth; extrusion of apposed teeth; destruction of periodontal tissues by occlusal force and food packing; increased sensitivity for dental caries; and disturbances on eruption pathway of succedaneous teeth. Therefore, periodic check-ups and proper treatments are required. There are many treatment options on infraoccluded deciduous molars such as periodic observation, conservative method, restoration and space regaining with extraction of the teeth. The choice of treatment may depend on the presence of succedaneous teeth, time of diagnosis and degree of infraocclusion. In this case report, three patients showing displacement of the second premolars due to infraocclusion of upper second primary molars, were treated by means of space regaining with removable orthodontic appliances and extraction of ankylosed primary molars. All malpositioned permanent premolars in the 3 cases showed ordinary eruption pathways after treatment.

Measurement of Respiratory Motion Signals for Respiratory Gating Radiation Therapy (호흡동조 방사선치료를 위한 호흡 움직임 신호 측정)

  • Chung, Jin-Beom;Chung, Won-Kyun;Kim, Yon-Lae;Lee, Jeong-Woo;Suh, Tae-Suk
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2005.04a
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    • pp.59-63
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    • 2005
  • Respiration motion causes movement of internal structures in the thorax and abdomen, making accurate delivery of radiation therapy to tumors in those areas a challenge. Accounting for such motion during treatment, therefore, has the potential to reduce margins drawn around the clinical target volume (CTV), resulting in a lower dose to normal tissues (e.g., lung and liver) and thus a lower risk of treatment induced complications. Among the techniques that explicitly account for intrafraction motion are breath-hold, respiration gating, and 4D or tumor-tracking techniques. Respiration gating methods periodically turn the beam on when the patient's respiration signal is in a certain part of the respiratory cycle (generally end-inhale or end-exhale). These techniques require acquisition of some form of respiration motion signal (infrared reflective markers, spirometry, strain gauge, thermistor, video tracking of chest outlines and fluoroscopic tracking of implanted markers are some of the techniques employed to date), which is assumed to be correlated with internal anatomy motion. In preliminary study for the respiratory gating radiation therapy, we performed to measurement of this respiration motion signal. In order to measure the respiratory motion signals of patient, respiration measurement system (RMS) was composed with three sensor (spirometer, thermistor, and belt transducer), 4 channel data acquisition system and mobile computer. For two patients, we performed to evaluation of respiratory cycle and shape with RMS. We observed under this system that respiratory cycle is generally periodic but asymmetric, with the majority of time spent. As expected, RMS traced patient's respiration each other well and be easily handled for application.

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Clinical Study on 2 Cases of Patients of Common Peroneal Nerve Palsy(Foot Drop) Improved by Motion Style Treatment (Motion Style Treatment로 호전된 족하수 환자 2례 보고)

  • Lee, Jin-Ho;Park, Jong-Min;Jung, Sung-Yup;Kim, Sung-Yong;Shin, Joon-Shik;Park, Won-Sang
    • The Journal of Korea CHUNA Manual Medicine
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    • v.6 no.1
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    • pp.119-126
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    • 2005
  • The purpose of this study is to report the patients with common peroneal nerve palsy, who improved by motion style treatment.(M.S.T.) The clinical study on 2 case of patients with herniation of nucleus pulposus, L4-5, L5-S1 combined foot drop, who had been hospitalized in Ja-Seng Oriental Hospital. We checked the motor grade and subjective improvement at interval of 3days under the treatment of M.S.T. After 2-3 weeks of treatment, the movement and power of ankle joint improved to nearly normal range. The subjective improvement was 70% compared with Rt. ankle and range of active motion increased from Gr.1-2 to Gr.4

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Quaternary Toham Basin (제4기 토함분지)

  • Choi Sung-Ja;Hong Dukgeun;Chwae Ueechan;Kim Myungjin;Lee Seog-kyu;Murray Andrew S.
    • Economic and Environmental Geology
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    • v.37 no.5
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    • pp.533-541
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    • 2004
  • A steadily consolidated conglomerate formation (CCF) is developed thickly around Tabjeong-ri and Janghang-ri to the east of Tohamsan, Gyeongju City. The CCF has been regarded to a basal conglomerate, Cheonbug Conglomerate, of the Yonil Group by Tateiwa (1924). Son et al. (2000) correlated the CCF to the Songjeon Formation, which occupies the southwestern block of Tertiary Waup Basin. However, the Songjeon Formation stratigraphically does not face to the extension of the CCF. OSL (Optically Stimulated Luminescence) data on the reddish brown to bluish gray psammitic layers, which are intercalated in the CCF, yielded to 85∼92 ka. Therefore, the age of CCF constrains to the last interglacial stage (MIS 5c-5e) rather than the Early Miocene Cheonbug Conglomerate. The Late Pleistocene Tohamsan Formation (TF) is newly named to the CCF and is subdivided to megabreccias and boulders. A rectangular basin, in which the TF is accumulated, is bounded by Oedong and Yonil faults (segments of Yonil Tectonic Line) and is given a name of Toham Basin. Neotectonically, Pliocene EW-transpression gave an effect of the top-up-to-the-west reverse faulting and the accompanied normal fault movement during the last interglacial age (ca. 100 ka). The basin is graben type, in which basin fills are composed of collapsed colluvial deposits, TF.

Using the Arthroscopic Remplissage of Anterior Shoulder Instability with Hill-Sachs Lesion (전방 견관절 불안정성에서 Hill-sachs 병변의 관절경적 Remplissage)

  • Ko, Sang-Hun;Jung, Kwang-Hwan;Shin, Seung-Myeong;Park, Han-Chang
    • Clinics in Shoulder and Elbow
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    • v.14 no.1
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    • pp.53-58
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    • 2011
  • Purpose: We evaluated the minimal 1 year follow-up results (shoulder stability and the clinical and functional results) for the Remplissage technique to fill a Hill-Sachs lesion. Materials and Methods: The subjects were 12 patients who could be followed up for more than 12 months after the "Remplissage" procedures in our hospital from December 2008 to November 2009. Their mean age was 27.9 years old and the mean follow-up was 19 months. The evaluations included the ROM, the ASES score, the KSSI score, the ROWE score and postoperative MRI. Results: On the postoperative functional evaluation after an average of 16 months, the ASES score improved from 50.8 preoperatively to 78.3 postoperatively, the KSSI score improved form 44.5 preoperatively to 81.0 postoperatively and the ROWE score improved from 40.2 preoperatively to 84.3 postoperatively. After an average 14 months for all the cases, the range of movement was nearly in the normal range, which is 178.6${\pm}$18.6 (165~180) degrees for forward flexion and 49.3${\pm}$10 (43~60) degrees for external rotation. Conclusion: For recurrent shoulder instability with a large Hill-Sachs lesion, the Remplissage technique has a good outcome after more than 1 year follow-up in terms of the shoulder stability and the clinical and functional results.

The Objective Measurement of the Lung Parenchyma Motion for Planning Target Volume Delineation (폐 부위 Planning Target Volume(PTV)설정시 폐 움직임의 객관적 측정)

  • Chung, Weon-Kyu;Cho, Jeong-Gill
    • Radiation Oncology Journal
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    • v.15 no.4
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    • pp.387-392
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    • 1997
  • Purpose : To quantify the movement of lung Parenchyma for ICRU 50 Planning Target Volume (PTV) delineation of the lung region. Materials and Method : Fluoroscopic observations and measurements are Performed on 10 patients with chest region cancer who have normal putmonary functions We have divided the lung region into 12 parts for the right lung, 10 parts for the left lung and four to five Points of lung parenchyma were selected for anatomical analysis Points, Fluoroscopic images are sent to a computer and then movements are measured. Results : Both lowe lobes showed the longest longitudinal movements because of breathing (average 14.1mm, maximum 22.1mm), while anteroposterior displacement showed the smallest value. Lateral movements of the lung parenchyma averaged 6.6mm, and the maximum value was 9.1mm, (both hilar regions showed maximum values because of cardiac motion) Conclusion : We could quantify the lung movements by measuring parenchyma displacements. The movements of both upper lobes were less than those of the middle and upper lobes in longitudinal and transverse movements. Optimal margins can be selected for PTV delineation using these results.

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