• Investigative Magnetic Resonance Imaging
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• v.13 no.1
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• pp.40-46
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• 2009

Purpose : The purpose of this study was to investigate the quantitative evaluation of the corticospinal tract (CST) at the multiple levels by using functional MRI (fMRI) co-registered to diffusion tensor tractography (DTT). Materials and Methods : Ten normal subjects without any history of neurological disorder participated in this study. fMRI was performed at 1.5 T MR scanner using hand grasp-release movement paradigm. DTT was performed by using DtiStudio on the basis of fiber assignment continuous tracking algorithm (FACT). The seed region of interest (ROI) was drawn in the area of maximum fMRI activation during the motor task of hand grasp-release movement on a 2-D fractional anisotropy (FA) color map, and the target ROI was drawn in the cortiocospinal portion of anterior lower pons. We have drawn five ROIs for the measurement of FA and apparent diffusion coefficient (ADC) along the corona radiata (CR) down to the medulla. Results : The contralateral primary sensorimotor cortex (SM1) was mainly found to be activated in all subjects. DTT showed that tracts originated from SM1 and ran to the medulla along the known pathway of the CST. In all subjects, FA values of the CST were higher at the level of the midbrain and posterior limb of internal capsule (PLIC) than the level of others. Conclusion : Our study showed that co-registered fMRI and DTT has elucidated the state of CST on 3-D and analyzed the quantitative values of FA and ADC at the multiple levels. We conclude that co-registered fMRI and DTT may be applied as a useful tool for clarifying and investigating the state of CST in the patients with brain injury.

• Sleep Medicine and Psychophysiology
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• v.5 no.1
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• pp.45-53
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• 1998

Objectives : The change of sleep patterns commonly occurs in association with the pregnancy. This study was to investigate sleep habits during the course of normal pregnancy. Methods : Sleep habits questionnaire was administered to healthy women in their first trimester(TR1) of pregnancy and then the same questionnaire was repeatedly administered during their second(TR2) and third(TR3) trimesters. The following aspects were assessed : patterns of night sleep, daytime status, sleep posture, reasons for sleep alteration, and the experience of any particular parasomnias, as well as sleep problem-related treatment or medication. Data analysis was based on 26 women who maintaind good health throughout their pregnancy and completed the questionnaire three times. Results : In comparisons between each trimester and non-pregnant state, total night sleep time, daytime tiredness, and sleepiness were significantly increased in all trimesters. Sleep latency was significantly decreased in TR1 and TR2, but not in TR3. In addition, refreshed feeling on waking the following day was significantly decreased and the number of awakenings during night sleep was significantly increased in TR3, but not in TR1 and TR2. In comparisons between trimesters, there was a significant increase in sleep latency, daytime sleepiness and the number of awakenings during night sleep and a significant decrease in refreshed feeling on waking the following day in TR3 compared to TR1 and TR2. Over the course of pregnancy, the rate of lateral position during sleep was gradually increased and all the pregnant women took the lateral sleeping posture in TR3. The major reasons for sleep pattern alteration were nausea, vomiting and heartburn in TR1, urinary frequency, fetal movement and ache in hips in TR2, and urinary frequency, fetal movement, cramp in legs and backache in TR3. Conclusion : These findings are expected to be useful for educating pregnant women about sleep hygiene. In future studies, the underlying factors and mechanisms regarding sleep patterns during pregnancy will need to be clarified.

• Journal of the Earthquake Engineering Society of Korea
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• v.2 no.4
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• pp.41-52
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• 1998

The Dongnae Fault in the southeastern part of the Korean Peninsular is not a single fault but a complex fault zone composed of numerous minor faults. In order to deduce the paleostress tensor evolving the Dongnae Fault, we measured 329 faults in outcrops around the fault zone and analyzed the geometries of them. Most of them are steeply dipping(>65˚) and fall into three groups striking N10E, N30E and N70E. More than one half of them show the rakes less than 30˚ Paleostress tensor analysis using the collected fault data has been conducted with the Angelier's direct inversion method and the Choi's method. As result, four different principal paleostress axes each of which subtends an independent tectonic event are found. They are; (1) NNE-SSW compression and ESE-WNW extension (Event I), (2) NNE-SSW extension (Event II), (3) ESE-WNW extension (Event III) and (4) ENE-WSW compression and NNW-SSE extension (Event IV) in chronology. Therefore, the tectonic movement around the Dongnae Fault was firstly governed by strike-slip faulting related to Event I. Afterward, normal faults were formed by Event II and Event III. Finally, the dextral strike-slip faults along the major trace of the Dongnae Fault were formed in NNE direction related to Event IV.

• Journal of Oral Medicine and Pain
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• v.18 no.2
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• pp.121-130
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• 1993

Mandibular rest position is very essential position because in that position, masticatory muscularture can be reciprocally coordinative and unstrained. So obtaining a good ability to establish and maintain rest position in non-functioning state is mandatory for treatment of patient with craniomandibular disorders. In general, many types of mandibulr movement exercise start from rest position and use the sense of muscle relearning, that is, muscle smoothness and relaxation, throughout the exercise period. In this study, 44 normal subjects for control group and 37 patients with craniomandibular disorders for experimental group participated and they were classified into 3 subgroups, respectively. One method to guide mandibular rest position was used for one subgroup, so theree methods were used for this study, 1)self-guided rest position without any education, 2) guided by Rocabado's tongue rest position, 3) guided through swallowing after Dawson's centric relation. To record electromyographic activity, Bioelectric processor EM2 (Myotronics, U.S.A.) was used. The numbers of sessions from start to stable resting electromyographic level and muscle activities in stable state were recorded and two recordings which were first and second, 3 days after first recording, were done, The data were processed with SPSS/PC+package. The obtained results were as follows : 1. Mean number of sessions in second recording were fewer than those in first recording in both groups. In comparison among 3 subgroups, mean number of sessions of subgroup guided through Dawson's method were fewer than those of other groups though it is not statistically significant. 2. There was a difference of mean number of sessions between control and experimental group in first recording, but in second recording there was no difference in any cases. 3. Mean value of muscle activity were generally not different without regard to group and method if once come to stable resting position level. Mean value of muscle activity of guided subgroups showed a tendency of decreasing in second recording than in first recording. However, in self-guided subgroup there was a inconsistent pattern. 4. The amounts of change in session number from first to second recording in control group were fewer than those in experimental group.

• Journal of Radiation Protection and Research
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• v.35 no.2
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• pp.63-68
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• 2010

The ultimate goal of radiation treatment is to use enough radiation dosage in order to examine a tumor while protecting normal tissue. Respiratory guided radiotherapy is being clinically implemented to examine a given stabilized area in order to compensate for the problems of patient breathing. This study investigates the effects of breathing movements on 40 patients with liver cancer through the actual radiation therapy plan using 4D-CT and respiratory guided radiotherapy using RPM. Using a commercial RPM respiratory gating system 4D-CT, we acquired 4D CT on multislice helical CT scanners that use different approaches to 4D CT image reconstruction. The results from analyzing forty patients according to age and direction showed no relationship between gender and transition change. The mean left-right, anteroposterior, and craniocaudal total movements were $3.19{\pm}1.29$, $5.44{\pm}2.07$, and $12.54{\pm}4.70$ mm, respectively. Changes were the largest with CC directions and as patients advanced in age, movements were larger. Therefore, as changes occur in treatment areas because of movements caused from breathing, respiratory gating system is put into operation to revise movement and can increase the radiotherapeutics effects in treating liver cancer.

• PNF and Movement
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• v.8 no.3
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• pp.27-37
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• 2010

Purpose : The aim of this study was to investigate the effects of stepper exercise using lower extremity patterns of PNF(Proprioceptive neuromuscular facilitation) on ankle muscle strength and balance ability of females in their twenties. Method : Twenty subjects participated in this experiment were carried out the exercise program dose of 5 days per week for 2 weeks. They were divided into two groups; using twist stepper group(lower extremity patterns of PNF group, n=10) and using straight stepper group(n=10). The effects of twist stepper and straight stepper were evaluated by measurements of normal standing(NSEO, NSEC), and dynamic type 1 and dynamic type 2, respectively. For each case, the experimental data were obtained about static balance in 3 items : mean X speed, mean Y speed and velocity moment, that of dynamic balance in 4 items : mean X speed, mean Y speed, time, distance. Results : The results of this study were as follows; 1) In straight stepper group, the statistically significants were significants were shown on right/left ankle muscle strength in case of dorsi-flexion. 2) In twist stepper group, the statistically significants were significants were shown on right/left ankle muscle strength in case of dorsi-flexion. 3) In straight stepper group, the statistically significants were significants were shown on right ankle muscle strength in case of plantar-flexion. 4) In twist stepper group, the statistically significants were significants were shown on right/left ankle muscle strength in case of plantar-flexion. Conclusion : The above results revealed that twist stepper exercise using lower extremity patterns of PNF was more effective than straight stepper exercise for improving the ankle muscle strength.

• 제어로봇시스템학회:학술대회논문집
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• 2004.08a
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• pp.1469-1473
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• 2004

We suggest how to program off-line robot path along shoes' outsole shape in the footwear buffing process by a 5-axis microscribe system like robot arms. This microscribe system developed consists a 5-axis robot link with a turn table, signal processing circuit, PC and an application software program. It makes a robot path on the shoe's upper through the movement of a microscribe with many joints. To do this, first it reads 5-encoder's pulse values while a robot arm points a shoes' outsole shape from the initial status. This system developed calculates the encoder pulse values for the robot arm's rotation and transmits the angle pulse values to the PC through a circuit. Then, Denavit-Hartenberg's(D-H) direct kinematics is used to make the global coordinate from robot joint one. The determinant is obtained with kinematics equation and D-H variable representation. To drive the kinematics equation, we have to set up the standard coordinates first. The many links and the more complicated structure cause the difficult kinematics problem to solve in the geometrical way. Thus, we can solve the robot's kinematics problems efficiently and systematically by Denavit-Hartenberg's representation. Finally, with the coordinate values calculated above, it can draw a buffing gauge-line on the upper. Also, it can program off-line robot path on the shoes' upper. We are subjected to obtaining shoes' outline points, which are 2 outlines coupled with the points and the normal vector based on the points. These data is supposed to be transformed into .dxf file to be used for data of automatic buffing robot. This system developed is simulated by using spline curves coupled with each point from dxf file in Autocad. As a result of applying this system to the buffing robot in the flexible footwear manufacturing system, it can be used effectively to program the path of a real buffing robot.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.17 no.2
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• pp.55-62
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• 2017

Gaucher disease (GD) is an autosomal recessive lysosomal storage disorder caused by beta-glucosidase deficiency. An 18 month-old male with hepatosplenomegaly, anemia, thrombocytopenia, and growth retardation referred to our hospital. The patient showed neurological symptoms, such as supranuclear gaze palsy and developmental delay. Bone marrow biopsy performed to rule out malignancy and the results revealed no malignant cell; however, abnormal histiocytes suggesting storage disease was noted. Based on hepatosplenomegaly, bicytopenia and unexplained neurologic manifestations, enzyme activity and genetic analysis were conducted emergently with a strong suspicion of GD. Beta-glucosidase activity in leukocyte was decreased. GBA sequencing to confirm the diagnosis revealed compound heterozygous pathogenic variants (i.e., c.754T>A, c.887G>A), both previously reported as the cause of neuronopathic GD. Under the diagnosis of type 3 GD, the patient immediately received enzyme replacement therapy (ERT). After 17 months of ERT, the size of spleen decreased, and hemoglobin and platelet count returned to normal. In addition, the activity of chitotriosidase and angiotensin converting enzyme decreased. However, myoclonic movement and generalized seizure occurred at the age of 19 months and antiepileptic drug was started. Other neurological deterioration including supranuclear gaze palsy and developmental delay also persisted. A new therapy to overcome neurologic problems should be developed for patients with type 3 GD.

• Journal of the Korean Geotechnical Society
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• v.31 no.7
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• pp.29-39
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• 2015

The vertical load imposed on the bucket foundation is transferred from the soil inside the bucket to the bottom of the foundation, and also to the outer surface of the skirt. For the design of a bucket foundation installed in sand, the vertical load transfer characteristics have to be clearly identified. However, the response of bucket foundations in sand subjected to a vertical load has not been investigated. In this study, we performed two-dimensional axisymmetric finite element analyses and investigated the vertical load transfer mechanism of bucket foundation installed in sand. The end bearing capacity of bucket foundation is shown to be larger than that of the shallow foundation, whereas the frictional resistance is smaller than that for a pile. The end bearing capacity of the bucket foundation is larger than the shallow foundation because the shear stress acting on the skirt pushes down and enlarges the failure surface. The skin friction is smaller than the pile because the settlement induces horizontal movement of the soil below the tip of the foundation and reduces the normal stress acting at the bottom part of the skirt. The calculated bearing capacity of the bucket foundation is larger than the sum of end bearing capacity of shallow foundation and skin friction of pile. This is because the increment of the end bearing capacity is larger than the reduction in the skin friction.

• Journal of the Korea Convergence Society
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• v.11 no.4
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• pp.71-78
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• 2020

The purpose of this study is to investigate the effect of wearing clothes, Level B, and Level C PPE on normal CPR using mannequins. The paramedics who participated in this experiment were 20 paramedics with more than 5 years of experience in firefighting area C. It was found that chest compressions in the process that hand off time was 11.9 seconds in the uniform wearing group, 11.4 seconds in the level C PPE wearing group, and 13.1 seconds in the SCBA wearing group. In other words, wearing personal protective equipment prevents the movement of paramedics and uses compensatory movements, which may increase the difficulty of efficient first aid. If this situation persists, it may cause fatigue and damage to the body of paramedics. Rescue and paramedics should wear level personal protective equipment in case of emergencies and conduct rescue and CPR training.