• Applied Microscopy
• /
• 제27권3호
• /
• pp.321-332
• /
• 1997

The dermal papilla is known to playa major role in influencing the form and dynamics of the hair follicle, which probably involves regulatory substances crossing the basal lamina. But little is known about the junctions between the dermal papilla and the surrounding epithelial cells of the hair bulb, or between the connective tissue and the epithelial cells on the outside of the hair follicle. This study was performed to identify the ultrastructural differences between dermoepidermal junction of the skin and connective tissue-epithelial junctions on the outside of the hair follicle and around the dermal papilla of normal anagen hair follicles in the human fetal scalp skin. Electron microscopic findings of dermoepidermal junction in scalp skin showed that basal lamina was very irregular and undulated, and it contained many attachment plaques of hemidesmosomes with sub-basal dense plates, tonofilaments, and anchoring filaments. Also invaginations of plasma membrane of basal keratinocytes were seen. There were clear differences both on the outside of the follicle and around the dermal papilla as compared with similar junction in the skin. In particular, neither hemidesmosomes nor tonofilaments, as seen in dermoepidermal junction, were observed in the dermal papilla. Also attachment plaque, sub-basal dense plate and anchoring filaments were not observed at the junction on the outside of the follicle and the dermal papilla. There were some differences between connective tissue-epithelial junctions on the outside of the hair follicle and around the dermal papilla, ie, smoothness of basal lamina and orthogonal arrangement of collagen fibers were seen in the outside of hair follicle, but not in the dermal papilla. These results indicate that the mechanical connection between the hair follicle and the connective tissue component is much weaker than that between the corresponding components in skin, and it reflects the dynamic processes during the anagen phase of the hair follicle compared to the relatively permanent state of the epidermis.

• Journal for History of Mathematics
• /
• 제31권5호
• /
• pp.251-269
• /
• 2018

Empirical probability and classical probability, which are two interpretations of Kolmogorov's axiom, are two ways to recognize the chances of events occurring in the real world. In this paper, I analyzed and suggested the contents of the high school textbooks ${\ll}$Probability and Statistics${\gg}$, associated with two interpretations of probability and experiments on which two interpretations are based. By presenting the cases required expressly stating what the experiment is for supporting students' understanding of some concepts, it was discussed that stating or not stating what the experiment is should be carefully determined by the educational intent. Especially, I suggested that in the textbooks we contrast the good idea of calculating the ratios of two possibilities in the imaginary world of the classical probability with the normal idea of grasping the chances of events through the frequencies in the real world of the empirical probability, with distinguishing the experiments in two interpretations of probability. I also suggested that in the textbooks we make it clear that the Weak Law of Large Numbers justifies our expectations of the frequencies' reflecting the chances of events occurring in the real world under ideal conditions. Teaching and learning about the aesthetic elements and the practicality of imaginary mathematical thinking supported by these textbooks statements could be one form of Humanities education in mathematics as STEAM education.

• Journal of the Institute of Convergence Signal Processing
• /
• 제1권1호
• /
• pp.15-22
• /
• 2000

The analysis of power spectrum based on linear AR model is applied widely to quantize the response of autonomic nerve noninvasively, In this paper, we estimate the power spectrum density for heartrate variability of the electrocadiogram and pulse wave for short term data(less than two minute), The time series of heart rate variability is obtained from the time interval(RRI, PPI) between the feature point of the electrocadiogram and pulse wave for normal person, The generated time series reconstructed into new time series through polynomial interpolation to apply to the AR mode. The power spectrum density for AR model is calculated by Burg algorithm, After applying AR model, the power spectrum density for heart rate variability of the electrocadiogram and the pulse wave is shown smooth spectrum power at the region of low frequence and high frequence, and that the power spectrum density of electrocadiogram and pulse wave has similar form for same subject.

• Journal of Korean society of Dental Hygiene
• /
• 제20권4호
• /
• pp.435-445
• /
• 2020

Objectives: This study investigated the relationship between obesity and dental caries of Korean adolescents. Methods: Data from the Korea National Health and Nutrition Examination Survey (KNHNES VI) (2013 to 2015) were used and targeted adolescents aged 13 to 18 years. For statistical analysis, the SPSS 18.0 program was used, and the significance level was set at 0.05. Results: For the general and health-related characteristics, female students (p=0.001) showed higher decayed, missing, and filled teeth (DMFT) index than male students. Furthermore, DMFT showed higher tendency, as age was higher (p<0.001). Smoking (p=0.011) and drinking experience (p=0.027) revealed higher DMFT. The dental caries experience was significantly different among students who were female (p=0.033), older (p=0.001), and overweight or underweight (p=0.022). In the BMI for the general and health-related characteristics, male students had higher obesity rate than female students (p=0.003), and obese subjects had higher dental checkup in the last year (p=0.013). In multiple linear regression analysis of obesity and DMFT, the unadjusted model showed that the obesity group's DMFT was about 0.8 higher than that of the normal group (p=0.024). However, statistical significance was not shown in the adjusted models. In the logistic regression analysis of obesity and dental caries experience, the unadjusted model 1 (1.93 times), the adjusted model 2 (1.79 times), and model 3 (1.76 times) showed significantly higher dental caries experience. Conclusions: Both obesity and dental caries are related to diet habits and lifestyles and have a negative impact on adult health. Therefore, it is necessary to create a healthy social environment around the adolescent, and proper intervention through education is required to form healthy habits.

• Applied Microscopy
• /
• 제28권1호
• /
• pp.91-105
• /
• 1998

The present study is undertaken to investigate the hypertrophical changes of the corpus allatum (corpora allata, CA) after the ovariectomy in Blattella germanica. In particular, the ultrastructural aspects of the normal and ovariectomized conditions, and induced factors of the hypertrophic phenomenon are focused. Ultrastructure of the CA from an immediately emergent adult is similar to that of the last larval stage that has stopped secreting juvenile hormone. The CA is composed of undifferentiated cells, exhibiting an electron-lucent matrix, a few mitochondria and less smooth endoplasmic reticulum. The karyoplasm occupy most of the cytoplasm. Electron-dense materials are filled with the intercellular spaces and gap junctions are also found. Almost no ultrastructural changes have been noticed during seven days until the oviposition. However, considerable changes in structure have been detected soon after the oviposition. Mitochondria are increased dramatically in number and cristae, and changed to the filamentous form with a high electron density. In addition, Golgi complexes, microtubules, and polysomes are also increased. After an oviposition, the total volume of the CA are decreased again. The volume of the CA are increased continuously, hypertrophy, after the ovariectomy. Morphological aspects of the CA in an early stage after the removal are similar to the structure of the secondary egg maturation. Large and electron dense globules are observed in the ovariectomized CA cytoplasms and they are present in those cells for a long period of time. Yet such a hypertrophical phenomenon occur only in the specific cells. The hypertrophy are caused by hollowing the part of the CA cells and later filling such site with polysomes. In 42 days after the ovariectomy, the nuclear membranes disappear in the CA cells, thus, exhibiting the prokaryotic-like features. Some results of the current study will contribute to the establishment of the model that explain unusual changes accompanied by certain treatment in insects and/or further in animals.

• Science of Emotion and Sensibility
• /
• 제12권1호
• /
• pp.137-144
• /
• 2009

This study aims to develop a 3D map which allows users to better understand the overall topography and to memorize the general concepts of the current location for tourists. The Map also utilizes different forms and color codes of the block units in the panoramic view. First, in preparation for making the road block unit, 28 types of roads presented in common map were defined. Based on the definitions, 12 dominant groups were formed. In designing each form, visual correlation was considered. Second, 42 types of terrain features presented in normal maps were defined for making the panoramic block unit. Then, 2 dominant groups, each contains 5 subgroups, were made according to the assemble pattern and the size of area. On the basis of the grouped units, the panoramic block units were produced with 3D pole line graphics maintaining integration. Lastly, each panoramic block units were categorized by color classes such as blue, green, gray and brown class. The overall color combination of the work was evaluated as well harmonized since the Moon&Spencer's Aesthetic measure value exceeds 0.5.

• Korean Journal of Head & Neck Oncology
• /
• 제15권2호
• /
• pp.222-225
• /
• 1999

Background and Objectives: Medullary thyroid carcinoma(MTC) is a rare tumor derived from the parafollicular C cells of the thyroid gland accounting for 5-10% of all thyroid malignancies. In Korea, there has been a few case report of medullary thyroid carcinoma(MTC) but their clinical analysis were not exactly studied. So, we made clinical study of 10 patients diagnosed as medullary thyroid carcinoma. Materials and Methods: We reviewed clinical data of 10 patients who were diagnosed as medullary thyroid carcinoma(MTC) from April 1973 to August 1998 at National Medical Center. Results: The incidence of MTC was 2.3% of all thyroid cancer and their mean age were 44.2 years old. Preoperative thyroid scan showed cold nodule in all patients and thyroid function test(TFT) was within normal range. Of the 10 patents, only 4 patients had diagnosis of MTC in preoperative fine needle aspiration biopsy. All the patients underwent total thyroidectomy with central neck dissection. Two patients with cervical lymph node metastasis underwent total thyroidectomy, central neck dissection and modified neck dissection. Two patients (20%) showed recurrence at the site of neck, lung, mediastinum, bone and liver. Conclusion: Most MTC is sporadic form and have peak incidence in the fifth decade and female preponderance. Preoperative fine needle aspiration biopsy is considered to be a clinically useful diagnostic method, but its accuracy is not considered as much high as others. Total thyroidectomy with central neck dissection may be an useful surgical modality in treating medullary thyroid carcinoma.

• Mass Spectrometry Letters
• /
• 제2권1호
• /
• pp.1-7
• /
• 2011

China's rapid economic growth has resulted in significant environmental side effects. Therefore, China has been interested in reducing her dependence on foreign oil and gas by developing technologies needed for hydrogen, in addition to her increasing energy mix of nuclear and renewable energy form, such as solar and wind power. There are three isotopes of hydrogen, i.e. protium (P or H), deuterium (D), and tritium (T). Both deuterium and tritium are important materials in nuclear fuel cycle industry. Tritium is one of the critical radioactive nuclides. Planning for and implementing contamination control as a part of normal operation and maintenance activities is an important function in any hydrogen facility, especially tritium facility. The development of hydrogen isotopes analysis is the key issues in this area. Mass spectrometry (MS) with medium (about 600) and high resolution (> 1,400) is commercially available; however, the routine analysis of hydrogen isotopes is done with low-resolution MS (< 200) in China. This paper summarizes the progress of MS measurement technology for hydrogen isotope abundance in China, focusing on our lab's research program and technical status. An analyzing method has been introduced for accurate measurement of tritium abundance in the H.D.T system by low resolution MAT-253 MS. The quotient of compression ratio coefficient is determined by building up equipment for laboratory-scale preparation of secondary standard gases and by considering the difference in sensitivity between hydrogen isotopes. The results show that the measured value is reproducible within the relative error range of 0.8% for gas samples of different tritium abundance.

• Tuberculosis and Respiratory Diseases
• /
• 제62권1호
• /
• pp.51-55
• /
• 2007

In the average adult with a normal immune state, Epstein-Barr virus pneumonia is very rare, especially in the form of interstitial lung disease. According to recent studies, the Epstein-Barr virus is also associated with lymphocytic interstitial pneumonia, AIDS and Langerhans cell histiocytosis, but not with sarcoidosis. BOOP is caused by lung injury due to an infection or drug intoxication, and is related to connective tissue disease or bone marrow transplantation, but is sometimes idiopathic. We experienced a patient with symptoms and signs of interstitial lung disease, with confirmed BOOP and EBV ingection from an open lung biopsy and serologic examination, respectively Herein, this case is reported, with a review of the literature.

• Korean journal of applied entomology
• /
• 제39권3호
• /
• pp.193-197
• /
• 2000

Wolbachia, vertically transmitted bacterial endosymbionts, is known to induce cytoplasmic incompatibility (CI), parthenogenesis, or feminization in some insect species. The Wolbachia found to exist symbiotically as a non-virulent form in Drosophila melanogaster, however popcorn is a lethal strain of Wolbachia, which causes tissue degeneration and early death of its adult host. Popcorn-infected flies showed the delayed duration of an egg and larvae, and their pupal period and life span reduced. The oviposition and egg-hatching rate of popcorn-infected flies were decreased 15% and 80%, respectiv~ly, compared to those of the normal Wolbachia-infected flies. The pupation and emergence rates of popcorn-infected flies were 67% and 65%, respectively. When popcorn-infected flies were crossed with Wolba-chia-infected flies, and vice versa, both crosses resulted in a significant reduction in egg production, egg¬hatching, pupation, and emergence rate, and their progeny revealed the popcorn syndrome. When popcorn-infected male flies were crossed with uninfected females, popcorn was not detected in their progeny. Popcorn also maternally transmitted in flies, but it did not induce CI and affected on its host life cycle as a virulence.