• Title/Summary/Keyword: Normal cognition

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Development and Validation of a Machine Learning-based Differential Diagnosis Model for Patients with Mild Cognitive Impairment using Resting-State Quantitative EEG (안정 상태에서의 정량 뇌파를 이용한 기계학습 기반의 경도인지장애 환자의 감별 진단 모델 개발 및 검증)

  • Moon, Kiwook;Lim, Seungeui;Kim, Jinuk;Ha, Sang-Won;Lee, Kiwon
    • Journal of Biomedical Engineering Research
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    • v.43 no.4
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    • pp.185-192
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    • 2022
  • Early detection of mild cognitive impairment can help prevent the progression of dementia. The purpose of this study was to design and validate a machine learning model that automatically differential diagnosed patients with mild cognitive impairment and identified cognitive decline characteristics compared to a control group with normal cognition using resting-state quantitative electroencephalogram (qEEG) with eyes closed. In the first step, a rectified signal was obtained through a preprocessing process that receives a quantitative EEG signal as an input and removes noise through a filter and independent component analysis (ICA). Frequency analysis and non-linear features were extracted from the rectified signal, and the 3067 extracted features were used as input of a linear support vector machine (SVM), a representative algorithm among machine learning algorithms, and classified into mild cognitive impairment patients and normal cognitive adults. As a result of classification analysis of 58 normal cognitive group and 80 patients in mild cognitive impairment, the accuracy of SVM was 86.2%. In patients with mild cognitive impairment, alpha band power was decreased in the frontal lobe, and high beta band power was increased in the frontal lobe compared to the normal cognitive group. Also, the gamma band power of the occipital-parietal lobe was decreased in mild cognitive impairment. These results represented that quantitative EEG can be used as a meaningful biomarker to discriminate cognitive decline.

An Analysis on Confucian Values of China Normal University Students - focused on the Q Methodology - (중국 사범대학생의 유교적 가치관 유형 분석 - Q방법론적 접근 -)

  • Yeo, Sang Woon;Li, Zhangpei;Li, Xiaohui
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.7 no.11
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    • pp.273-283
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    • 2017
  • This study aims to analysis the types of features of confucian values of China normal university students. To achieve this purpose, Q methodology is applied. This study was conducted at Sichuan Normal University in China. Total 42 students and 47 statements collected through literature research. The implementation were formed in four types, statism, traditionalism, nominalism, and naturalism. Through this study, from the perspective of international relations, family relations, and friendship, all four type of features were presented intellectualized intelligentiae. The common feature of the four types is gender role, and the cognition of gender role is changing, and women will becoming an independent individual. Although confucian values had made great contribution for the development of Chinese traditional culture, it is an undeniable fact that some ideas not according with the modern social demand for development are hidden in the back.And we should look at and appreciate confucian values from a comprehensive and dialectic view.

Children's Developmental Understanding of Varieties of Expertise (3, 4, 5세 아동의 전문지식에 대한 이해 발달)

  • Song, Young Joo
    • Korean Journal of Child Studies
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    • v.26 no.3
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    • pp.29-42
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    • 2005
  • In this study on the development of children's understanding of varieties of expertise, forty-seven 3-, 4- and 5-year old children were asked to differentiate expertise in the minds of adults, using twenty-four questions consisting of 3 levels of inferences, False belief tasks were also provided to discover correlations with knowledge of various pockets of expertise, Results revealed that 4- and 5-year olds made more correct attributions than 3-year olds. Children also inferred attributions properly on familiar experts, understanding of stereotypical roles, normal functioning, and underlying principles, in that order. Children's concepts of varieties of expertise were correlated with their understanding of false beliefs.

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Discriminative Feature Vector Selection for Emotion Classification Based on Speech (음성신호기반의 감정분석을 위한 특징벡터 선택)

  • Choi, Ha-Na;Byun, Sung-Woo;Lee, Seok-Pil
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.64 no.9
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    • pp.1363-1368
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    • 2015
  • Recently, computer form were smaller than before because of computing technique's development and many wearable device are formed. So, computer's cognition of human emotion has importantly considered, thus researches on analyzing the state of emotion are increasing. Human voice includes many information of human emotion. This paper proposes a discriminative feature vector selection for emotion classification based on speech. For this, we extract some feature vectors like Pitch, MFCC, LPC, LPCC from voice signals are divided into four emotion parts on happy, normal, sad, angry and compare a separability of the extracted feature vectors using Bhattacharyya distance. So more effective feature vectors are recommended for emotion classification.

Sorted compressive sensing for reconstruction of failed in-core detector signals

  • Gyu-ri Bae;Moon-Ghu Park;Youngchul Cho;Jung-Uk Sohn
    • Nuclear Engineering and Technology
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    • v.55 no.5
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    • pp.1533-1540
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    • 2023
  • Self-Powered Neutron Detectors(SPNDs) are used to calculate core power distributions, an essential factor in the safe operation of nuclear power plants. Some detectors may fail during normal operation, and signals from failed detectors are isolated from intact signals. The calculated detailed power distribution accuracy depends on the number of available detector signals. Failed detectors decrease the operating margin by enlarging the power distribution measurement error. Therefore, a thorough reconstruction of the failed detector signals is critical. This note suggests a compressive sensing based methodology that rationally reconstructs the readings of failed detectors. The methodology significantly improves reconstruction accuracy by sorting signals and removing high-frequency components from conventional compressive sensing methodology.

A Proposal for Developing a Situated Learning Support Systems-Based on an MMORPG

  • PIAO, Cheng Ri
    • Educational Technology International
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    • v.6 no.2
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    • pp.59-67
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    • 2005
  • The primary purposes of this study are to develop a Situated Learning Support System based on an MMORPG (Massively Multiplayer Online Role Playing Game) and to investigate applications of Situated Learning theory both hypothetically and practically. In Situated Leaning theory, cognition is interpreted as a dynamic system related to situation, context and activity. According to this theory, learning context, social interaction and personal direct experience are also emphasized. A virtual reality learning system based on an MMORPG provides context, social interaction and a learning environment able to provide direct experiences. However, such a system has been difficult for teachers to develop. This study aims to develop a support system facilitating the construction of a Situated Learning System based on an MMORPG. This study proposes new research and practical applications of Situated Learning theory using educational games.

Comparative Study on Dietary Behavior, Nutrition Knowledge and Cognition of Body Image, Weight Control and Nutrition Education of Middle School Students according to Gender (남녀 중학생의 식행동, 영양지식 및 체형, 체중조절과 영양교육에 관한 인식비교)

  • Park, Hyun-Ae;Rhie, Sung-Gyo;Won, Hyang-Rye
    • The Korean Journal of Community Living Science
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    • v.18 no.3
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    • pp.481-491
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    • 2007
  • The purpose of this study is to find out how important providing nutrition education to young students is. The study is based on the assumption that students' food behavior, nutrition knowledge and cognition of body image, weight control and nutrition education are considerably influenced by gender. A total of 495 students (249 boy and 246 girl students) were surveyed in one middle school located Siheungsi, Gyeonggido. The average height and weight of the boy and girl students are 164.6 cm, 54.4 kg and l58.5cm, 47kg, respectively. According to average BMI, the boy students($20.0kg/m^2$) are in the normal state. However, the girl students($18.2kg/m^2$) are underweight. For the status of meal intake, 52.4% of the students took breakfast everyday. Female students had dinner with lower intake frequency than males(p<0.05). For snack intake, the kinds of snack differ according to gender(p<0.05); more milk for male and more fruit for female students. The scores of dietary behavior based on Mini Dietary Assessment were 21.5/30 for male and 21.3/30 for female students. The nutrition knowledge scores of 4.6/10 for male and 4.6/10 for female students were not significantly different according to gender. The score of dietary behavior is based on Mini Dietary Assessment. The survey shows that in terms of the experience of weight control, 35.5% of the girl students have made an effort to watch their weight and 21.8% of the boy students have tried controlling their weight(p<0.0001). It turns out that the students who have been provided nutrition education are more satisfied with their body shape than those who have never been provided nutrition education(p<0.05).

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Apolipoprotein E Polymorphism and Cognitive Function Change of the Elderly in a Rural Area, Korea (일개 농촌지역 노인의 아포지단백 E 다형성과 인지기능 변화)

  • Kim, Sang-Kyu;Hwang, Tae-Yoon;Lee, Kyeong-Soo;Kang, Pock-Soo;Cho, Hee-Soon;Bae, Young-Kyung
    • Journal of Preventive Medicine and Public Health
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    • v.42 no.4
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    • pp.261-266
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    • 2009
  • Objectives : The aim of this study is to examine the cognitive function change related to aging, the incidence of cognitive impairment, and the association between apolipoprotein E polymorphism and cognitive impairment through a follow-up of the elderly with normal cognitive ability at baseline. Methods : Two hundred and fifteen subjects aged 65 and over were surveyed in February, 1998 (baseline survey), and their cognitive function was assessed again in 2003 1st follow-up) and the once again in 2006 (2nd follow-up). Ninety one subjects completed all surveys up through the 2nd follow-up and their cognitive function scores using MMSE-K (Korean Version of the Mini-Mental State Examination) and the distribution of apolipoprotein E allele were analyzed. Results : The cognitive function scores decreased with aging and the difference between baseline and the 2nd follow-up scores of the study increased with the age group. The incidence rate of cognitive impairment through an 8-year follow-up was 38.5% and higher in older age groups. Age was the only significant factor for incidence of cognitive impairment, but there was no significant association between apolipoprotein E genotype and incidence of cognitive impairment. Conclusions : The cognition of the elderly decreased with aging and the association of apolipoprotein E genotype with incidence of cognitive impairment was not significant in this study. To confirm the association between apolipoprotein E polymorphism and incidence of cognitive impairment further studies will be needed.

Effects of general and oral health status on dementia in the elderly in some areas (일부 지역 노인의 전신건강과 구강건강상태가 치매에 미치는 영향)

  • Kim, Yu-Rin;Heo, Seong-Eun;Jang, Kyeung-Ae;Kang, Hyun-Kyung
    • Journal of Korean society of Dental Hygiene
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    • v.21 no.2
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    • pp.151-158
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    • 2021
  • Objectives: The purpose of this study was to identify the effects of general and oral health status on dementia. Methods: Questionnaires were used for the KDSQ-C (Korean Dementia Screening Questionnaires-Cognition) and to investigate the oral health status of the participants. An independent t-test was conducted to analyze the differences between general health and oral health status depending on the normal and suspected dementia groups. Logistic regression analysis was performed to assess the effects of general and oral health status on dementia. Results: Regarding the health status of the subjects assessed by the KDSQ-C, the higher the current health status and the higher the exercise status, the lower was the dementia level (p<0.05). During the assessment of oral health conditions in KDSQ-C subjects, dementia was more suspected in subjects with dental decay and periodontal disease than in those without dental decay (p<0.05). Conclusions: Dementia has been confirmed to be closely related to general and oral health conditions. Therefore, oral health-related programs are essential for dementia prevention programs. Since dental hygienists are best suited for providing oral care to older adults with dementia, it is considered essential to reflect their occupation in future national policies.

Effect of Korean Red Ginseng in individuals exposed to high stress levels: a 6-week, double-blind, randomized, placebo-controlled trial

  • Baek, Ji Hyun;Heo, Jung-Yoon;Fava, Maurizio;Mischoulon, David;Choi, Kwan Woo;Na, Eun Jin;Cho, Hana;Jeon, Hong Jin
    • Journal of Ginseng Research
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    • v.43 no.3
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    • pp.402-407
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    • 2019
  • Background: To investigate the neurobiological evidence supporting the adaptogenic effects of Korean Red Ginseng in reducing the harmful consequences of stress using a double-blind, placebo-controlled trial. Method: Sixty-three subjects with high stress levels were randomized to receive an orally administered, double-blind, 6-week treatment with Korean Red Ginseng (n = 32) or placebo (n = 31). All participants underwent a comprehensive psychological evaluation using Beck Depression Inventory and Stress Response Inventory, cognitive evaluation using the continuous performance test, biological evaluation by measuring blood levels of lipids, catecholamines, inflammation markers, and heart rate variability at baseline and after 6 weeks. Results: At baseline, both groups showed no significant differences in age, sex, years of education, Beck Depression Inventory, and Stress Response Inventory. After 6 weeks, triglyceride levels were significantly increased within the normal limit in the Korean Red Ginseng group (F = 4.11, p = 0.048), and the epinephrine level was decreased in this group (F = 4,35, p = 0.043). The triglyceride increase was significantly associated with epinephrine decrease (B = 0.087, p = 0.041), suggesting that Korean Red Ginseng may stabilize the sympathetic nervous system. In addition, we detected a significant group by time effect in the visually controlled continuous performance test, suggesting positive effects of Korean Red Ginseng on cognition. Conclusion: Korean Red Ginseng might help to stabilize the sympathetic nervous system and improve cognition in individuals with high stress.