• Structural Engineering and Mechanics
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• v.87 no.5
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• pp.405-418
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• 2023

This study focused on the effectiveness of seismic isolation technique in case of a reinforced concrete structure with soft story defined as the stiffness irregularity between adjacent stories. In this context, a seismically isolated 3-story reinforced concrete structure was analyzed by gradually increasing the first story height (3.0, 4.5, and 6.0 m). The seismic isolation system of the structure is assumed to be composed of lead rubber bearings (LRB). In the analyses, isolators were modeled by both deteriorating (temperature-dependent analyses) and non-deteriorating (bounding analyses) hysteretic representations. The deterioration in strength of isolator is due to temperature rise in the lead core during cyclic motion. The ground motion pairs used in bi-directional nonlinear dynamic analyses were selected and scaled according to codified procedures. In the analyses, different isolation periods (Tiso) and characteristic strength to weight ratios (Q/W) were considered in order to determine the sensitivity of structural response to the isolator properties. Response quantities under consideration are floor accelerations, and interstory drift ratios. Analyses results are compared for both hysteretic representations of LRBs. Results are also used to assess the significance of the ratio between the horizontal stiffnesses of soft story and isolation system. It is revealed that seismic isolation is a viable method to reduce structural damage in structures with soft story.

• Earthquakes and Structures
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• v.16 no.4
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• pp.401-413
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• 2019

The concept of base isolation for equipment is well known. Its application in buildings and structures is rather challenging. Introduction of horizontal flexibility at the base helps in proper energy dissipation at the base level thus reducing the seismic demand of the super structure to be considered during design. The present study shows the results of a series of numerical simulation studies on seismic responses of secondary system (SS) housed in non-isolated and base-isolated primary structures (PS) including equipment-structure interactions. For this study the primary structure consists of two similar single bay three-store reinforced cement concrete (RCC) Frame building, one non-isolated with conventional foundation and another base isolated with Lead plug bearings (LPB) constructed at IIT Guwahati, while the secondary system is modeled as a steel frame. Time period of the base isolated building is higher than the fixed building. Due to the presence of isolator, Acceleration response is significantly reduced in both (X and Y) direction of Building. It have been found that when compared to fixed base building, the base isolated building gives better performance in high seismic prone areas.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.7
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• pp.2257-2285
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• 2022

Cyber-physical systems (CPS) have been growing exponentially due to improved cloud-datacenter infrastructure-as-a-service (CDIaaS). Incremental expandability (scalability), Quality of Service (QoS) performance, and reliability are currently the automation focus on healthy Tier 4 CDIaaS. However, stable QoS is yet to be fully addressed in Cyber-physical data centers (CP-DCS). Also, balanced agility and flexibility for the application workloads need urgent attention. There is a need for a resilient and fault-tolerance scheme in terms of CPS routing service including Pod cluster reliability analytics that meets QoS requirements. Motivated by these concerns, our contributions are fourfold. First, a Distributed Non-Recursive Cloud Model (DNRCM) is proposed to support cyber-physical workloads for remote lab activities. Second, an efficient QoS stability model with Routh-Hurwitz criteria is established. Third, an evaluation of the CDIaaS DCN topology is validated for handling large-scale, traffic workloads. Network Function Virtualization (NFV) with Floodlight SDN controllers was adopted for the implementation of DNRCM with embedded rule-base in Open vSwitch engines. Fourth, QoS evaluation is carried out experimentally. Considering the non-recursive queuing delays with SDN isolation (logical), a lower queuing delay (19.65%) is observed. Without logical isolation, the average queuing delay is 80.34%. Without logical resource isolation, the fault tolerance yields 33.55%, while with logical isolation, it yields 66.44%. In terms of throughput, DNRCM, recursive BCube, and DCell offered 38.30%, 36.37%, and 25.53% respectively. Similarly, the DNRCM had an improved incremental scalability profile of 40.00%, while BCube and Recursive DCell had 33.33%, and 26.67% respectively. In terms of service availability, the DNRCM offered 52.10% compared with recursive BCube and DCell which yielded 34.72% and 13.18% respectively. The average delays obtained for DNRCM, recursive BCube, and DCell are 32.81%, 33.44%, and 33.75% respectively. Finally, workload utilization for DNRCM, recursive BCube, and DCell yielded 50.28%, 27.93%, and 21.79% respectively.

• Earthquakes and Structures
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• v.7 no.6
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• pp.1223-1240
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• 2014

Seismic isolation has been established as an effective earthquake-resistant design method and the lead rubber bearings (LRBs) are among the most commonly used seismic isolation systems. In the scientific literature, a sharp bilinear model is often used for capturing the hysteretic behaviour of the LRBs in the analysis of seismically isolated structures, although the actual behaviour of the LRBs can be more accurately represented utilizing smoothed plasticity, as captured by the Bouc-Wen model. Discrepancies between these two models are quantified in terms of the computed peak relative displacements at the isolation level, as well as the peak inter-storey deflections and the absolute top-floor accelerations, for the case of base-isolated buildings modelled as multi degree-of-freedom systems. Numerical simulations under pulse-like ground motions have been performed to assess the effect of non-linear parameters of the seismic isolation system and characteristics of both the superstructure and the earthquake excitation, on the accuracy of the computed peak structural responses. Through parametric analyses, this paper assesses potential inaccuracies of the computed peak seismic response when the sharp bilinear model is employed for modelling the LRBs instead of the more accurate and smoother Bouc-Wen model.

• Structural Engineering and Mechanics
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• v.84 no.4
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• pp.503-515
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• 2022

Based on the sliding isolation concrete LSS (liquid-storage structure), the specific seismic vulnerability is analyzed according to the general failure mode. In this study, 12 seismic inputs with different characteristics are used, and their acceleration peak values are modulated. By inputting these waves to the sliding isolation concrete storage structure, the finite-element models of different concrete rectangular LSSs are obtained and analyzed, and the failure probabilities are obtained according to the IDA (incremental dynamic analysis) curves of the structure. The results show that when the seismic acceleration peak value gradually increases from 0.1 g to 1.0 g, the failure probability of LSS gradually increases with the increase in friction coefficient. However, the failure probability of a sliding isolation LSS is less than 100% and far less than the failure probability of a non-isolated rectangular LSS, which shows that an isolated liquid storage structure continues working under a big earthquake. Thus, the sliding isolation for the concrete LSS has a significant damping effect.

• The Journal of Korean Society of Virology
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• v.28 no.4
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• pp.347-358
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• 1998

To analyze the correlation between biological phenotypes of HIV-1 isolates and disease progression, we selected 9 long-term non-progressors (LTNP) and 12 rapid progressors (RP) from HIV-1 infected Korean. We isolated HIV-1 isolates by culture of PBMC of LTNP and RP with normal PBMC and measured HIV-1 p24 antigen production. The HIV-1 isolation rate from LTNP was 55.6% (5/9). And 4 HIV-1 LTNP isolates were non-syncytium inducing (NSI) phenotype and showed slow/low replication. The HIV-1 isolation rate from RP was 91.7% (11/12) which was higher than that from LTNP. Besides 3 RP HIV-1 isolates which showed syncytium inducing (SI) phenotype, 8 RP HIV-1 isolates showed NSI phenotype in normal PBMC and MT-2 cell line. All RP HIV-1 isolates replicated more rapidly than LTNP HIV-1 isolates. Comparing the replication kinetics and syncytium forming capacity of HIV-1 isolates from LTNP and RP, we suggest that the difference of biological phenotype of HIV-1 isolates could be related with disease progression of HIV-1 infected persons.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2001.04a
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• pp.425-432
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• 2001

This paper presents the studies of the characteristics of dynamic behavior of single layer latticed domes with laminated rubber bearing and establishes the effectiveness of the system. The base isolation system installed between base and structures reduces the responses due to earthquake motions and increases the natural period of structures. Numerical analysis is carried out using modal superposition method and Newmark-βmethod which is linear acceleration method with (equation omitted) : 1/2 and β : 1/6. The time interval Δt for response calculation is 0.001 sec. Damping ratio is 2 % as Rayleigh damping and El Centro NS(1940) as earthquake motion is the input excitation data. The acceleration response of dome with base isolation is reduced to 30 % of the response of non-isolation system. From the results of the numerical studies on the models, it is confirmed that base isolation system effectively suppresses the responses of the domes subjected to horizontal earthquakes.

• Korean Journal of Veterinary Service
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• v.22 no.3
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• pp.221-237
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• 1999

To investigate the specificity of rapid slide agglutination test for pullorum-gallinarum diseases and to obtain a basic data for avian salmonellosis control, salmonella isolation was peformed for the layer chickens positively reacted in pullonlm-typhoid agglutination test. The biochemical, serological and antimicrobial properties of the isolates were examined. The results obtained through this study were summarized as follows; 1. Of 2,384 chickens tested by the agglutination test, 606 chickens (25.4%) were positive reactors. 154 of 606 reactors and 49 of the non-reacting chickens were investigated for salmonella isolation, resulting in isolation of 68 strains of salmonellae from 27 chickens. 2. By organs, the isolation frequency from liver, cecum, spleen, ovary and gall bladder showed 8.9% (18 strains), 8.9% (18 strains), 7.4% (15 strains), 4.4% (9 strains) and 3.9% (8 strains), respectively. 3. By culture medium the combination of selenite broth and MacConkey agar revealed the highest isolation rate and the enrichment culture by delayed secondary enrichment culture method was found the most effective for salmonella isolation. 4. The serotypes of 68 salmonella isolates were identified as 3 strains of S pullorum, 24 strains of S gallinarum, 15 strains of S typhimurium, 8 strains of S enteritidis, 7 strains of S paratyphi A, 5 strains of S typhimurium and 6 strains of the other salmonellae. 5. The serotypes of 8 salmonella strains isolated from 49 chickens non-reacting in pullorum-typhoid agglutination test were identified as 3 strains of S typhimurium and 5 strains of S infantis. 6. When 24 chickens of which 68 strains of salmonellae isolated were examined by microplate agglutination test, the average antibody titer for pullorum antigen was $2^{5.25}$. The chickens at antibody titer between $2^3$ and $2^5$ showed the higher frequency of isolation as compared with the chickens at the other titers. 7. When salmonella isolates were tested the antimicrobial drug sensitivity by disk diffusion method, S paratyphi A were highly sensitive by 100% to ATM and GM, S typhimurium, by 88% to AM, CIP, IMP and TN, S infantis, by 100% to AM, CRO, ENR and PIP, S enteritidis,by 100% to IMP and PIP, S pullorum, by 100% to ATM, CRO, ENR and PIP and S gallinarum, by 92% to CRO, CIP and PIP.

• Biomedical Science Letters
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• v.16 no.3
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• pp.133-138
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• 2010

Despite of the increasing importance of environmental mycobacteria, detection and identification of mycobacteria from environmental sources including water have been fraught with technical difficulties. Although, several protocols to optiruize isolation of mycobacteria from water sources have been reported, standard method has not yet been established. In this study, usefulness of cetylpyridinium chloride (CPC), a cationic quaternary ammonium compound, for the isolation of environmental mycobacteria from diverse water samples was evaluated. For this, water samples from diverse water sources such as effluent water, lake water, and underground water were collected, treated with diverse concentrations of CPC, and plated on the solid agar plates. Subsequently individual colonies grown on the plates were sequence analyzed for identification of each colony. In brief, the results from this study showed that the growth of mycobacteria was enhanced by use of CPC as a pre-treatment reagent to water samples by inhibiting growth of other non-mycobacteria in water. In fact, the effect of CPC to decontaminate non-mycobacteria for isolation of mycobacteria was better than 1~4% of NaOH, which is a routinely used decontaminating reagent widely employed for culturing mycobactera from sputum specimens. Therefore, the results from this study seems to support that the CPC pre-treatment may be useful for isolation of mycobacteria from diverse sources including clinical specimens which are often contaminated with other bacteria.

• Earthquakes and Structures
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• v.15 no.5
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• pp.513-528
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• 2018

A typical viable technique to decrease the seismic response of liquid storage tanks is to isolate them at the base. Base-isolation systems are an efficient and feasible solution to reduce the vulnerability of structures in high seismic risk zones. Nevertheless, when liquid storage tanks are under long-period shaking, the base-isolation systems could have different impacts. These kinds of earthquakes can damage the tanks readily. Hence, the seismic behaviour and vibration of cylindrical liquid storage tanks, subjected to earthquakes, is of paramount importance, and it is investigated in this paper. The Finite Element Method is used to evaluate seismic response in addition to the reduction of excessive liquid sloshing in the tank when subjected to the long-period ground motion. The non-linear stress-strain behaviour pertaining to polymers and rubbers is implemented while non-linear contact elements are employed to describe the 3-D surface-to-surface contact. Therefore, Nonlinear Procedures are used to investigate the fluid-structure interactions (FSI) between liquid and the tank wall while there is incompressible liquid. Part I, examines the effect of the flexibility of the isolation system and the tank aspect ratio (height to radius) on the tank wall radial displacements of the tank wall and the liquid sloshing heights. Maximum stress and base shear force for various aspect ratios and different base-isolators, which are subjected to three seismic conditions, will be discussed in Part II. It is shown that the composite-base isolator is much more effective than other isolators due to its high flexibility and strength combined. Moreover, the base isolators may decrease the maximum level pertaining to radial displacement.