• Journal of Sasang Constitutional Medicine
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• v.23 no.2
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• pp.208-217
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• 2011

1. Objectives: The purpose of this study was done to compare Sasang Constitution diagnostic rate between taking Sasang Constitution herb medicine patients and non taking group. 2. Methods: We collected data from 430 patients who were visited at the Department of Sasang Constitution, College of Oriental Medicine, Dong-eui University from November 2006 to September 2010. We classified them into two group. One was taking Sasang Constitution herb medicine patients group, the other was non taking group. For Sasang Constitution Diagnosis, they all have done SSCQ-P questionnaire. and a Sasang Constitution specialist diagnosed constitution. According to reactions after taking herb medicine, the patients of taking group were confirmed their constitutions. We checked Sasang Constitution diagnostic rate from each groups'(the whole subjects, taking herb medicine patients group, non taking herb medicine patients group) discriminant function. And to find out Sasang Constitution diagnostic rate, we applied discriminant functions to each other. 3. Results and Conclusions: 1) The whole subjects' diagnostic accuracy rate was 72.07%. 2) Taking herb medicine group's diagnostic accuracy Rate was 75.08%. Non taking herb medicine group's diagnostic accuracy rate applied taking group's discriminant function was 61.60%. 3) Non taking herb medicine group's diagnostic accuracy rate was 81.06%. Taking herb medicine group's diagnostic accuracy rate applied taking group's discriminant function was 57.14%.

• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.1
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• pp.130-135
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• 2013

We investigated the lung function change and quality of life in smokers after taking herbal medicine. The patients were divided into two groups(smoking and non-smoking). We measured lung function change by VRI and quality of life by BDI and Fatigue Scale Score before and after herbal medicine intake. And we examined changes of nicotine dependence, total smoking amount, tobacco flavor in smoking group. The VRI energy bar could not represent the change of the lung function in smoking group and non-smoking group. And there was no change of lung function by VRI in two group patients before and after herb medication. But after taking herb medicine, the patients who have abnormal sound in VRI were improved. The herbal medicine does not affect to the amount of smoking, tobacco flavor, nicotine dependence in Smoking patients. Smoking group were higher than non-smokers in BDI score and Fatigue Scale score. Smoking group were more improved than the non-smokers in BDI and Fatigue Scale Score after taking herbal medicine.

• The Journal of Pediatrics of Korean Medicine
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• v.20 no.3
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• pp.129-141
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• 2006

Objectives : The purpose of this study is to determine clinical efficacy of herbal medicine by evaluating SCORAD Index and total level of ceramaides in the skin of 13 children with atopic dermatitis Methods : Subjects are divided into two groups : Group 1(non-differentiation children treated with Saenghyeoryunbueom) and group 2(differentiation children treated with either pyungwisan, onchungum or gamitongsungsan). We determine SCORAD Index and total level of ceramaides in the skin of 13 children with atopic dermatitis before and after taking each of herbal treatment for 12 weeks. Results : After herbal prescription for 12 weeks, A SCORAD index of both group 1 and group 2 was decreased. However, the total level of ceramides in group 1 and group 2 was not altered after 12 weeks. When the correlation between the alteration of SCORAD index and ceramides levels was determined, the SCORAD index in group 1 was inversely correlated with the total level of ceramides(r=-0.994, p=0.006) In contrast, the alteration of SCORAD index in group 2 was not correlated with ceramide levels. Conclusions : The clinical efficacy of Saenghyeoryunbueom for non-differentiation children with atopic dermatitis is paralleled with the increased level of ceramides in skin. The clinical efficacy of pyungwisan, onchungum or gamitongsungsan for differentiation children with atopic dermatitis is not correlated with ceramide level in skin.

• Korean Journal of Clinical Pharmacy
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• v.22 no.2
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• pp.153-159
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• 2012

Licorice is a very useful herbal medicine frequently prescribed, but glycyrrhizin, one of its components, can cause pseudoaldosteronism presenting hypokalemia, metabolic alkalosis and hypertension as a result of prolonging a biological half-life of systemic steroid by strongly inhibiting the enzyme $11{\beta}$-hydroxysteroid dehydrogenase type 2. The risk factors for this side effect are still unclear. Here, 479 hospitalized patients taking herbal medicines including licorice for more than five days were recruited to analyze their serum potassium levels, under following parameters ; age and gender of patient, dose and period of licorice, disease state such as hypertension and with or without diuretics. They were divided into the non-occurrence group (over 3.5 mEq/L) and the occurrence group (under 3.5 mEq/L) of hypokalemia based on serum potassium levels during hospitalization. The average ages of the non-occurrence group and the occurrence group were $52.6{\pm}17.8$ and $68{\pm}10.5$, respectively (p < 0.001). But there were no noticeable differences in the daily dose of licorice, days of taking, and total dose between groups. Regression analysis showed that odd ratio of age (>60) and taking diuretics inducing hypokalemia was 3.5 (95%CI 1.5-8.1), 4.6 (95%CI 2.0-10.9) that indicates significant correlation with hypokalemia. Based upon this analysis, it is imperative to monitor regularly the risk of pseudoaldosteronism or hypokalemia not only when administered licorice of high dose for long period but also when combined it with diuretics causing hypokalemia to the elderly patients over 60 year old.