• Korean Journal of Animal Reproduction
• /
• v.9 no.2
• /
• pp.97-104
• /
• 1985

This study was conducted to investigate the effects of unilateral ovariectomy on the weight of the remaining ovary, the change of number of ovarian follicle, number of corpus luteum and serum progesterone level. Sixty Sprague-Dawley female rats, 23$\pm$2 days old, were divided into 2 groups (control and unilaterally ovariectomized goup) with 30 heads per groups. Each group was again subdivided into 6 groups according to 6 experimental periods; Day 4, 8, 12, 16, 20 and 24 after uniteral ovariectomy. Five arts at every 4 day intervals were sacrificed for the measuring of ovarian weight and for quantitative histologic examination of ovary and at the same time, blood samples were taken for the determination of serum progesterone level of radioimmunoassy. The results obtained were as follows: During the experimental periods, a significant hypertrophy occured in the remaining ovary of unilaterally ovariectomized group from day 16 after operation. The average ovarian weight of control group at day 16 was 21.0$\pm$1.7mg, which is samller than that of unilaterally ovariectomized group weighing 50.5$\pm$8.4mg(P<0.01). The ovarian weight of the unilaterally ovariectomized rats at day 20 and day 24 was 75.9$\pm$2.2 mg and 63.3$\pm$7.0 mg, which is heavier than those of control group; 29.1$\pm$2.3 and 26.3$\pm$1.7 mg(P<0.01 and P<0.01). 2. A same degree of ovarian follicle development was observed in the unilaterally ovariectomized group. Following unilateral ovariectomy and there was no change in total number of follicles larger than 130$\mu$ during the period from day 4 till day 24 after operation. 3. Although the size fo ovarian follicle did not significantly change between two groups from day 4 till day 16, the size of vesicular follicle in unilaterally ovariectomized group (406.3$\pm$26.2$\mu$) was significantly greater as compared to that of control group (323.8$\pm$19.3$\mu$)(P<0.05). 4. Corpus luteum in unilaterally ovariectomized and control group began to a, pp.ar from day 16 after operation and then the number of corpus luteum slightly increased. The number of corpus luteum in unilaterally ovariectomized group at day 24 ws remarkably increased (13.7$\pm$1.41) than that of control (5.2$\pm$2.01)(P<0.01). 5. Serum progesterone levels in unilaterally ovariectomized group were slightly higher than those of control but there were no significant difference between treatment groups.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.6
• /
• pp.2505-2510
• /
• 2014

Background: The standard radiotherapy (RT) fractionation practiced in India and worldwide is 50Gy in 25 fractions over 5 weeks to the chest wall or whole breast followed by tumour bed boost in case of breast conservation (BCS). A body of validated data exists regarding hypofractionation in breast cancer. We here report initial results for 135 patients treated at our center with the START-B type of fractionation. Materials and Methods: From May 2011 till July 2012, women with all stages of breast cancer (excluding metastatic), who had undergone BCS or mastectomy were planned for 40Gy in 15 fractions over 3weeks to chest wall/whole breast and supraclavicular fossa (where indicated) followed by tumour bed boost in BCS patients. Planning was done using Casebow's technique. The primary end point was to assess the acute toxicity and the cosmetic outcomes. Using cosmetic scales; patients were assessed during radiotherapy and at subsequent follow up visits with the radiation oncologist. Results: Of the 135 patients, 62 had undergone BCS and 73 mastectomy. Median age of the population was 52 years. Some 80% were T1&T2 tumours in BCS whereas most patients in mastectomy group were T3&T4 tumours (60%). 45% were node negative in BCS group whilst it was 23% in the mastectomy group. Average NPI scores were 3.9 and 4.9, respectively. Most frequently reported histopathology report was infiltrating ductal carcinoma (87%), grade III being most common (58%), and 69% were ER positive tumours, and 30% were Her 2 Neu positive. Triple negative tumours accounted for 13% and their mean age was young (43 yrs.) The maximum acute skin toxicity at the end of treatment was Grade 1 in 94% of the mastectomy grouppatients and 71% in BCS patients. Grade 2 toxicity was 6% in mast group and 23% in BCS group. Grade 3 was 6% in BCS group, no grade 3 toxicity in mastectomy patients and there was no grade 4 skin toxicity in any case. Post RT at 1 month; 39% of BCS patients had persisting Grade I skin reaction which was only 2% in mastectomy patients. At 3 months post RT, 18% patients had persisting hyperpigmentation. At 6 months 8% patients had persisting erythema in the BCS group only. Some 3% BCS and 8% mastectomy patients had lymph edema till the date of evaluation. Cosmetic outcome in BCS patients remained good to excellent 6 months post surgery and radiotherapy. 1 patient of BCS and 3 patients of mast had developed metastatic disease at the time of evaluation. Conclusions: Hypofractionated RT is well tolerated in Indian population with reduced acute skin toxicity and good cosmetic outcome. Regimens such as these should be encouraged in other centers to increase machine output time. The study is on-going to assess long term results.

• Journal of Nutrition and Health
• /
• v.30 no.3
• /
• pp.336-348
• /
• 1997

The objectives of this study were to examine the growth pattern of infants by anthropometric measurement according to the 5 feeding practices of infants with the subject of two hundred healthy newborn babies from their birth till sixty month of age at intervals of two months. Breast group(BF, n=38), formula group(FF, n=102) and mixed group(ME, n=14) were fed breast milk, formula milk, breast and formula milk, from birth till 6 mo. of age, respectively. Convert 1 group (C1F, n=14) and covert 2 group(CF, n=32) were fed breast milk and mixed milk at 2 mo. of age afterthat switched to formula milk, respectively. From these, the following results were made. All the infants of this study showed superiority to Korean standard growth rate in regards to each growth item for each month age. In the case of males, at their birth, the subscapular skinfold thickness and the total skin fold thickness in the BF group was significantly larger than in MF group and FF group(p<0.05). At 6th month age, the chese circumference of MF group was 45.9cm, and significantly larger than those of BF, FF and C2F groups(p<0.05). In the case of females, at theri birth and 2nd month age, there was no difference among all the feeding groups in regards to each growth rate. At 4th month age, the Kauf index of C1F group was 16.21 and significantly lower than those of four groups(p<0.05). And total skinfold thickness in BF group was larger than in C1F group. The increase rate per month age of all growth items were larger at 2nd month age than at the later months both in males and in females. And until 2nd month age males showed more increase than females in regards to each growth item but after 2nd month age, this sapect did not show up. Multiple linear regression was used to determine predictive factors for infant growth. It was expected that at 6th month age, in the measurement of head circumference and chest circumference and cross-sectional fat area, BF-males were bigger by 22-39% of the explanation index than the infants of other groups. As a result, in spite of the significant lower intakes of energy and nutrients in breast-fed infants than in formula-fed infants, breast-fed infants showed more growth than the average of Korean infant standard growth rate at every month age, and showed no significant growth difference among feeding groups.

• Economic and Environmental Geology
• /
• v.5 no.3
• /
• pp.133-144
• /
• 1972

The mine of our present concern is situated at Shim-ri, Gusan-myon, Changwon-gun, Kyongsang-namdo, with lattitude $128^{\circ}35^{\prime}{\sim}36^{\prime}N$ and longitude $35^{\circ}03^{\prime}{\sim}04^{\prime}E$. This mine has not been noticed until the intermittent geological survey for the ore deposits were initiated from September, 1967 till 1970. The main mineralized zones, No.1 and No.2 zones, were studied by the diamond drilling of 9 holes down to the total depth of 1,140m, and found to have ore reserves of Cu 1.99% ore, estimated to reach around $358,000{\frac{M}{T}}$ (proved $117,000{\frac{M}{T}}$, indicated $241,000{\frac{M}{T}}$), which triggered the new exploitation of this mine. Geological composition of the district near the mine is mainly from the andesite belonging to the Silla Series of Kyongsang System and the distribution is broadly spread. Ore deposits are the hydrothermal one, filling the shear zone formed alongside the andesite main joint. There are two stripes of copper bearing mineralized zone which are about 40~70 meters apart and parallel to each other, in addition to which two others are expected. The strike of the main mineralized zone lies at $N15^{\circ}{\sim}20^{\circ}W$, the dip at $60^{\circ}{\sim}70^{\circ}NE$. The principal components of the ore mineral are chalcopyrite, bornite and as secondary, cuprite, tenorite, azurite and malachite. Pyrite, magnetite, specular hematite, very little of galena, sphalerite, quartz, epidote, zoisite, chlorite and calcite are found as gangue mineral. Confirmed by the drilling, the main mineralized zone, No.1 zone, has the length of 320m, average width of 1.62m, Ag 26g/t, Cu 1.84% and the average width of the ore zone except the narrow barren andesite horse interposed in the mineralized zone is 1.32m with Ag 32g/t and Cu 2.26%. The mineralized zone No.2 is 340m long, 1.00m wide with Ag 30g/t and Cu 2.15%. Neglecting the barren andesite horse the width is 0.73m with Ag 42g/t and Cu 2.94%.

• Animal Bioscience
• /
• v.37 no.2
• /
• pp.253-260
• /
• 2024

Objective: The objectives of the present study were to evaluate the effects of once-a-day milk feeding on growth performance and routine behavior of preweaning dairy calves. Methods: At 22nd day of age, twenty-four Holstein calves were randomly assigned to one of two treatment groups (n = 12/treatment) based on milk feeding frequency (MF): i) 3 L of milk feeding two times a day; ii) 6 L of milk feeding once a day. The milk feeding amount was reduced to half for all calves between 56 and 60 days of age and weaning was done at 60 days of age. To determine the increase in weight and structural measurements, each calf was weighed and measured at 3 weeks of age and then at weaning. The daily behavioral activity of each calf was assessed from the 22nd day of age till weaning (60th day of age) through Nederlandsche Apparatenfabriek (NEDAP) software providing real-time data through a logger fitted on the calf's foot. Results: There was no interaction (p≥0.17) between MF and sex of the calves for routine behavioral parameters, body weight and structural measurements. Similarly, there was no effect of MF on routine behavioral parameters, body weight and structural measurements. However, the sex of the calves affected body weight gain in calves. Male calves had 27% greater total body weight and average daily gain than female calves. There was no effect of the sex of the calves on behavioral measurements. Collectively, in the current study, no negative effects of a once-a-day milk feeding regimen were found on routine behavioral and growth parameters of preweaning calves in group housing. Conclusion: Once-a-day milk feeding can be safely adopted in preweaning calves from 22nd day of age.

• Asian-Australasian Journal of Animal Sciences
• /
• v.25 no.7
• /
• pp.980-987
• /
• 2012

In order to investigate the effect of physical forms of starter diets on performance, weaning age, nutrient digestibility and rumen biochemical factors, 24 female of neonatal Brown Swiss calves (average body weight of $39.5{\pm}1.2kg$) were randomly assigned to three treatments. Dietary treatments were mashed (MS), pelleted (PS), and texturized (TS) starter using 8 calves from birth till 90 days of age in each treatment. Diets were formulated to be iso-nitrogenous with 21% crude protein. Based on the experimental results, calves that received PS and TS diets, had significant higher average daily gain (ADG) than those receiving MS (p<0.01). Dry matter intake in calves fed PS and TS was greater than calves fed MS (p<0.05), but there was no significant difference in feed efficiency. Treatments had no effect on initiation of rumination. Weaning age of calves in MS was longer than the other two treatments (p<0.05). Crude protein and organic matter digestibility in MS treated calves were lower than other treatments (p<0.05). No differences were observed in neutral detergent fiber (NDF) and ash digestibility among treatments (p>0.05). Ruminal pH was higher (p<0.01) in MS than the other groups, but ruminal ammonia (g/dl) concentration was not different among the treatments. Body measurements such as body length, pin width, hip width, pin to hip length, size of metacarpus and metatarsus bones, hip height, wither height, stomach size and heart girth were not significantly different among the treatments. Overall, it is concluded that starter diets in the form of pellet and texture can improve performance in neonatal Brown Swiss calves compared to the mashed form.

• Korean Journal of Soil Science and Fertilizer
• /
• v.49 no.4
• /
• pp.368-374
• /
• 2016

The perennial edible wild plants such as Aster glehnii, Solidago virgaurea subsp. gigantean, Allium ochotense, Athyrium acutipinnulum, Aruncus dioicus var. kamtschaticus and Codonopsis lanceolata have cultivated as the main income crops introduced into the fields about 30 years ago in Ulleung island. Soil samples were collected from 190 fields and assessed the effects of management practices on soil chemical properties at wild edible plant fields under no-till system. The strong acidic soils of pH 5.4 or less were detected in 45% of the soil samples. The level of soil organic matter was being held at mean $63{\pm}28g\;kg^{-1}$, 2.7 times higher than upland soils in Korea. Available phosphate and exchangeable potassium showed more than recommended levels of upland crops as $680{\pm}489mg\;kg^{-1}$ and $1.94{\pm}1.7cmol_c\;kg^{-1}$, respectively. The fields of Solidago and Aster showing strong soil acidity and high level of available phosphate and water soluble $NO_3{^-}$ were distinguished from other crops in analysis of variance and principal component analysis of soil chemicals. These results suggested that high frequency of acidic soil and high levels of available $P_2O_5$, exchangeable $K_2O$ and water soluble $NO_3{^-}$ were accompanied with the use of urea and NPK-fertilizer based on nitrogen in the field. However, further research is needed to understand the appropriate management of fertilization and the prevention of soil acidification for wild edible plants.

• Proceedings of the Korean Geotechical Society Conference
• /
• 2010.03a
• /
• pp.1302-1308
• /
• 2010

This study the change of the safety factor before and after the reinforcement were compared by performing the parameter research based on the limit equilibrium analysis regarding the same cross section after carrying out the safety factor before the reinforcement on the virtual section in order to observe the change of the safety factor of the slop reinforced with the slope planting reinforced earth, and the variation of the safety factor according to the increase of the length of the reinforcement materials and the change of the slope height was analyzed. As the result, the reinforcement effect was insignificant at no more than 0.6 of L/H, the reinforcement length ratio when the reinforcement length was increased, as the increase of the safety factor was slow comparing with the non-reinforced slope. At 3.0m of the slope height, reinforcement on the slope is not necessary, and at 3.0m to 5.0m of the slope height, the inclination was not influencing at no less than 0.6 of L/H. At 5.0m to 9.0m of the slope height, the safety factor was mostly secured on the slope at 0.8 of L/H and the over-reinforced slope appeared at no less than 1.0 of L/H. Also, the safety factor increased as the slope height increases and the slope gets steeper till 0.8 of L/H, but the slope steepness affects more on the increase of the safety factor than the reinforcement material, as the reinforcing force by the reinforcement material became steady.

• Journal of Korean Academy of Nursing
• /
• v.15 no.2
• /
• pp.34-48
• /
• 1985

The purpose of this study was to find out healtk education activities of the 435 school nurses in the secondary schools in Seoul. A questionaire was sent by mail on March 11, 1985 and received a total of 252 responds till April 4, 1985. Among them, 230 were included in final analysis. Those of 22 school nurses who have worked not more than one year were excluded. The results of the findings obtained of this study are summarized as follows: 1. An average number of health education activities carried out by the school nurses turned out to be 31.7 times/nurse/year. 2. The practice rates of health education activities by contents of health education were revealed as follows: on parasite disease 89.6%, hepatitis 89.1%, physical examination 87.3%, influenza 84.3%, etc. Health education on drinking and smoking, drug abuse were the lowest rate as 37.8% and 40.9%. 3. The practice rates of health education by the school nurses according to the health education methods were shown as follows: instruction by the teacher 90.9%, bulletin boards in the classroom 73.0%, message to home notices 72.676, etc. 4. Difficulties in carrying out health education programs by the school nurse were analysed accord-ing to Likert's five point scale. The scores on item to the no availability of teaching tools and tips were 3.90, no availability of audiovisual aids 3.801 lack of understanding from the school principals 3. 30, insufficient time of the school nurse 3.26, no guidance or unproper form of health education material 3.20, lack of knowledge of educational method 3.18. As a conclusion of this study, the development of the supporting system to health education activities and programs for improvement of school health education is strongly needed from policy making level.

• Restorative Dentistry and Endodontics
• /
• v.18 no.2
• /
• pp.447-462
• /
• 1993

To evaluate the marginal leakage in Class V cavity this study has been undertaken to compare the sandwich technique with the conventional method, and find out the effect of lining material, lining method, and polishing time on sandwich technique. Ninty extracted teeth were divided into eight test groups and a control group, and were prepared with a buccal Class V cavity. Four test groups were lined with Dentin Cement whereas the other four test groups were lined with Vitrabond. Half of the either group were lined 0.5mm short of the carvosurface margin and the rest were lined completely to the carvosurface margin. The four subgroups were further divided into specimens which were polished immediately and 24 hours after resin filling. The polished specimens were immersed in $37^{\circ}C$, 0.5% methylene blue solution for 24 hous after thermocycling at $5^{\circ}C$ and $55^{\circ}C$, 200 times and buccolingually sectioned. The sectioned specimens were examined dye penetration under the light microscope. The following results were obtained, 1. At the enamel margin, the conventional method showed a lower microleakage than the sandwich technique. The difference between the control and Vitrabond group was statistically significant(P<0.05), but no difference between the control and Dentin Cement group, and between the lining materials was observed. 2. At the dentinal margin, the sandwich technique showed a significant lower amount of microleakage (P<0.05), but there was no significant difference between the lining materials. 3. Regardless of the lining material, lining method, and polishing time used, values of microleakage were significantly higher at the dentinal margin compared to the enamel margin(P<0.05). 4. In specimens till the cavosurface margin, microleakage at the dentinal margin was less with the light-cured base than with the chemically-cured base, but there was no siginificantly difference between the lining materials regarding the lining method and polishing time. 5. The lining material, lining method, and polishing time did not affect the amount of micro leakage in the sandwich technique(P<0.05).