• Title/Summary/Keyword: Nim

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A Discrete Model of Brucellosis Happened in Korean Livestock Farms

  • Park, Junpyo;Kim, Byul Nim
    • Kyungpook Mathematical Journal
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    • v.47 no.4
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    • pp.601-608
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    • 2007
  • In this paper we introduce a discrete model of brucellosis happened in Korean livestock farms and numerically analyze its dynamical features. To do it, we consider parameters data supported by Livestock Cooperatives. To control brucellosis, we investigate the relationship among key parameters, as applications of our model. We hope that our model may be used to reduce brucellosis in Korean livestock farms.

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Mechanistic Studies on the Photochemical Degradation of Nifedipine

  • Shim, Sang-Chul;Pae, Ae-Nim;Lee, Yong-Jai
    • Bulletin of the Korean Chemical Society
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    • v.9 no.5
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    • pp.271-274
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    • 1988
  • Irradiaton of nifedipine in methylene chloride at 366 nm yielded 2,6-dimethyl-3,5-dicarbomethoxy-4-(2'-nitrosophen yl)-pyridine with the quantum yield 0.37, while irradiation at 254 nm initially gave nitroso compound which in turn is photooxidized to 2,6-dimethyl-3,5-dicarbomethoxy-4-(2'-nitrophenyl) -pyridine with the quantum efficiency of 0.014 on further irradiation in the presence of oxygen. The intramolecular hydrogen abstraction of nifedipine proceeded from the triplet excited sitate.

Developing a pharmacophore model for nonpeptide bradykinin antagonists

  • Park, Hae-Young;Choi, Su-Young;Lee, Su-Jin;Koh, Hune-Yeong;Pae, Ae-Nim
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.176.1-176.1
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    • 2003
  • Bradykinin is an autocoid related to acute and chronic pain and inflammation. The non-peptide bradykinin antagonists are of interest as novel anti-inflammatory therapeutics. To understand the structural basis for the bradykinin antagonistic activity and to guide the design of more potent compounds we analysed the three dimensional pharmacophore model. Seven active compounds very recently reported such as FR 167344, FR 173657, LF 160687, and bradyzide were used as our pharmacophore model analysis. (omitted)

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Molecular cloning, sequence polymorphism and genomic organization of far eastern catfish (Silurus asotus) GH gene

  • Park, Byul-Nim;Bang, In-Chul;Kim, Dong-Soo;Nam, Yoon-Kwon
    • Proceedings of the Korean Aquaculture Society Conference
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    • 2003.10a
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    • pp.42-42
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    • 2003
  • The far eastern catfish (Silurus asotus) growth hormone (GH) gene was cloned and characterized. The complete nucleotide sequences of genomic GH gene sequences as well as a catfish GH cDNA were obtained by RT-PCR and gene filter screening. The GH cDNA and genomic gene span 1.0 and 1.8 kb from the start codon to the polyadenylation signal, respectively. Both on cDNA and gDNA GH genes, the sequence polymorphism was detected including various silence mutations. The genomic GH gene comprised of only four exons and three introns, which was novel type of fish GH gene structure. The evolutionary relation of the catfish GH gene was inferred based on the comparative phylogenic analysis using the gene structures and sequences.

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