• Journal of Nutrition and Health
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• v.36 no.8
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• pp.841-850
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• 2003

Soy-based formula has been used for centuries in Korea. Soybeans contain phytochemicals with a biochemically active component, isoflavone. Isoflavone is a kind of phytoestrogens, structurally and functionally similar to estrogen. This study was conducted to investigate the effects of soy-based infant formula on growth, development, and isoflavone concentration in the plasma and urine. Thirty-nine healthy infants who were delivered at K university medical center were recruited. Experimental groups were the breast milk group (n = 15, BM) who were fed breast milk, soy-based formula group (n = 10, SBF) who were fed soy-based infant formula, and the casein-based formula group (n = 14, CBF) who were fed casein-based infant formula for 4 months. HPLC analysis was used to measure the concentration of isoflavones. The measurements of infant weight, length, head circumference and chest circumference were all in the normal growth range and were similar among the experimental groups. No significant differences were found in the scores of total mean of infant development test (Development Quotient, DQ) among the experimental groups. The isoflavone content of soy-based formula was significantly higher than. that of breast milk and casein-based formula. Plasma concentration of daidzein and genistein in the infants fed soy-based formula (daidzein : 264.1 ng/ml, genistein : 392.1 ng/ml) was significantly higher (p<.0001) than that in infants fed breast milk (daidzein : 3.4 ng/ml, genistein : 3.8 ng/ml) and casein-based formula (daidzein: 8.1 ng/ml, genistein: 9.3 ng/ml). Also, urinary daidzein and genistein concentrations in infants fed soy-based formula (daidzein: 19.82 $\mu$g/ml, genistein : 17.89 $\mu$g/ml) were significantly higher (p<.001) than those in infants fed breast milk (daidzein: 0.28 $\mu$g/ml, genistein : 0.22 $\mu$g/ml) and casein-based formula (daidzein : 0.45 $\mu$g/ml, genistein : 0.33 $\mu$g/ml).

• Korean Journal of Community Nutrition
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• v.16 no.4
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• pp.439-453
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• 2011

This study was performed to determine dietary and lifestyle factors associated with hypertension in Korean adolescents. Study subjects were 12~19 years (n = 521) adolescents who participated in the 2005 Korean National Health and Nutrition Examination Survey (KNHANES III). Subjects were divided into the hypertensive group (HG, n = 102) and normotensive group (NG, n = 419) by '2007 Korean children and adolescents growth standard' and the relationships between blood pressure and physical measurement, nutrients intakes, eating behaviors and health related factors were analyzed. HG showed significantly higher levels in weight, waist circumference and BMI than NG. The amount of nutrient intakes was not different between NG and HG. Index of nutritional quality (INQ) for phosphate was higher in HG compared with NG. In both male and female HG, INQ for iron was higher but INQ for vitamin B1 was lower than NG. HG revealed higher consumption frequencies of snack, yoghurt, and ice cream compared with NG. In eating and behavioral factors, 'dinner with family', 'eat proper amount', 'keep Korean traditional diet', alcohol drinking, and mean alcohol intake were significantly different between the two groups. By logistic regression method, risk factors for hypertension revealed in this study were gender (male), age (15~19 years), BMI (${\geq}\;85$ percentile), and not keeping Korean traditional diet. These results suggest that education program for hypertension prevention in adolescents should include eating habits improvement and lifestyle modification as well as weight control.

• Journal of Korean Society for Atmospheric Environment
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• v.11 no.E
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• pp.55-62
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• 1995

The distribution of airborne mercury was investigated from several districts of Seoul, five other major cities and two rural areas during the period April, 1994 to March, 1995. The method used in this study involves absorption of gaseous mercury on CHromosorb$^R$ A coated with gold and detection by cold vapor atomic absorption spectroscopy. The atmospheric mercury concentrations in Seoul ranged from N.D. to 120.17 ng m$^3$ (mean 27.01 $\pm 9.42 ng m^{-3}, N=139$), while those in rural areas ranged from 1.72 to 8.24 ng $m^{-3} (mean 4.57 \pm 3.07 ng m^{-3}, N=5$). The spatial distribution characteristics of mercury distribution in urban air were examined by comparing mercury levels as a function of the distance from the urban center. Temporal distribution trends of airborne mercury were also studied using the monthly mean mercury data of various districts in Seoul. The atmospheric mercury concentration around Mokdong wastes incinerator in Seoul were also investigated.

• 한국방재학회:학술대회논문집
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• 2008.02a
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• pp.417-420
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• 2008

Recently, the interest in NDMA(N-nitrosodimethylamine) has increased due to its recognition as a pollutant by Ontario Ministry of Environment and Energy and California Department of Health Sciences. It is, in fact, one of the DBPs(Disinfection By-products) which appears due to chlorination and is reported to be fatal if exposed continuously to human body. Due to uncertainty in mechanism to remove it, its treatment is not yet carried out. In this experiment, treatment of biological NDMA is carried out by letting it adsorbed on Granular Sludge and then filtering the medium through MF(Microfiltration) and UF(Ultrafiltration) membranes. Granular Sludge is adapted to aerobic and anaerobic conditions for 7 days and the experimental conditions are MLSS of 8000mg/L, COD of 250mg/L, TN of 12.5mg/L, and TP of 2.5mg/L. Several batch tests were carried out and samples were collected with the interval of 1 hour. Samples were measured by LSC(Liquid scintillation counter) after filtering by MF and UF. In batch test with granular sludge the permeate concentrations(removal efficiencies) of NDMA by MF and UF were 71.7ng/L(32.0%) and 62.0ng/L(43.7%) at aerobic state, and 52.0ng/L(49.2%) and 47.6ng/L(58.9%) at anaerobic state, respectively. Hence, UF membrane showed about 10% more removal efficiency than MF and removal efficiency at anaerobic condition was 15% more than that at aerobic condition.

• Journal of Haehwa Medicine
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• v.20 no.1
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• pp.39-50
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• 2011

In western, aromatherapy uses essential oils to prevent and treat disease, and is one of the ways to stay healthy. In oriental medicine, there was also a similar medical treatment using aromatic herbs for a long ago. The exisiting research of oriental medical herbs is mainly focused on the theory of qi and flavor(氣味論). But on aromatherapy used with aromatic herbs, it is necessary to study the aromatic herbs by aroma. So "xi$\bar{a}$ng p$\check{u}$, 香譜" and "b$\check{e}$n c$\check{a}$o g$\bar{a}$ng m$\grave{u}$, 本草綱目" mainly contain the study about clinical effects of aromatic herbs. And "b$\check{e}$n c$\check{a}$o p$\check{i}$n hu$\grave{i}$ j$\bar{i}$ng y$\grave{a}$o, 本草品彙精要"mainly explains the effects of medical herbs with five aroma classification of x$\bar{i}$ng(腥), sh$\bar{a}$n(膻), xi$\bar{a}$ng(香), ch$\grave{o}$u(臭), xi$\check{u}$(朽). The former one makes more clinical uses of medical herbs, and the latter one grows up the theory of medical herbs. This study is expected to have a good influence on aromatherapy and classification of oriental medical herbs.

• Korean Journal of Clinical Laboratory Science
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• v.47 no.4
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• pp.318-323
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• 2015

The aim of this study was to assess the association of metabolic syndrome and Vitamin D in Korean adults. The study subjects were Korean menopausal woman (n=4,340) who participated in the Korea National Health and Nutrition Examination Survey 2010~2012. After adjusting for factors such as age, body mass index, total cholesterol, smoking, and regular exercise, the mean 25(OH)D levels ($M{\pm}SE$) decreased with increasing metabolic syndrome score (MSS) (MSS 0, $18.18{\pm}0.29ng/Ml$; MSS 1, $18.09{\pm}0.21ng/mL$; MSS 2, $18.07{\pm}0.19ng/mL$; MSS 3, $18.04{\pm}0.21ng/mL$; MSS ${\geq}4$, $17.27{\pm}0.23ng/mL$), and the mean 25(OH)D level ($M{\pm}SE$) for metabolic syndrome ($17.66{\pm}0.16ng/mL$) decreased in comparison to non-metabolic syndrome ($18.11{\pm}0.14ng/mL$). In conclusion, our results suggest that an increase in metabolic syndrome score or metabolic syndrome are inversely associated with the vitamin D levels.

• Asian-Australasian Journal of Animal Sciences
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• v.11 no.1
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• pp.78-83
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• 1998

The objective of this study was to investigate the responsiveness of hypophysis and gonads to synthetic GnRH among prepubertal buffalo heifers at 12 months of age. Peripheral plasma FSH, LH, estradiol and progesterone level were measured in blood samples collected at 1 hr before and up to 18 days subsequent to the administration of $200{\mu}g$ GnRH (n=6) or saline (n=6) in Murrah buffalo heifers. The pretreatment peripheral plasma FSH, LH, estradiol and progesterone among GnRH treated heifers were $7.35{\pm}0.45ng/ml$, $1.08{\pm}0.3ng/ml$, $22.93{\pm}1.06pg/ml$ and $0.27{\pm}0.04ng/ml$ respectively. A quick elevation (p < 0.01) of FSH and LH within five min of GnRH administration was observed in all geifers. Although the peak FSH $(89.57{\pm}23.43ng/ml)$ and LH $(7.52{\pm}3.08ng/ml)$ reached by 10 min of GnRH administration, yet the animals differed both in terms of their amplitude response of FSH and LH release as well as in terms of time which animals took to exhiit maximum response to GnRH administration. The GnRH administration did not cause alteration in plasma estradiol and progesterone level. The present study suggests that the pituitary of 12 month buffalo heifers has capacity to synthesize and store of gonadotropin and have developed receptors for GnRH for a spike of gonadotropin release.

• Korean Journal of Ecology and Environment
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• v.40 no.2
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• pp.318-326
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• 2007

Characteristics of organophoshhorus pesticides (OPs) distribution were investigated in Shingu Reservoir, as a shallow eutrophic agriculture reservoir in Korea. In August 2006, IBP, DDVP and dyfonate were detected in the water column of Singu Reservoir, ranging from 1340.7 to 16030.1 ng $L^{-1}$, 58.7 to 127.6 ng $L^{-1}$ and N.D. to 20.3 ng $L^{-1}$, respectively, However, in September 2006, mevinfos, ethoprofos, phorate, chlorfenvinfos, and methidathion were also found in addition to IBP (202.5${\sim}$213.2 ng $L^{-1}$), DDVP (100.7${\sim}$340.6 ng $L^{-1}$) and dyfonate (N.D.${\sim}$25.0 ng $L^{-1})$. Maximum concentrations of OPs were observed at the middle depth in August, which might be related with photo-oxidation. On the other hand, IBP and DDVP among the OPs were detected in suspended particles, suggesting the relatively active adsorption reactivity. The composition of OPs varied temporally on account of the influence of inflow water from its surrounding areas. In the present study, the observed OPs concentrations seem to be not acute toBic levels to aquatic organisms in Shingu Reservoir, considering the standard monitoring levels of U.S. Environmental Protection Agency and Japan Ministry of Environment.

• Archives of Pharmacal Research
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• v.19 no.6
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• pp.475-479
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• 1996

Diethylcarbamazine (DEC, 1-diethylcarbamyl-4-methylpiperazine) is an antiparasitic piperazine derivative used in the treatment of lymphatic filariasis caused by Wuchereria bancrofti, Brugia malayi or grugia timori. DEC-N-oxide is a major metabolite in humans and has antifilarial activity. In carrying out pharmacokinetic studies, gas chromatographic analysis of DEC in plasma can be complicated by the presence of the metabolite, since the thermally unstable DEC-N-oxide is converted back to a material which coelutes with DEC under the conditions of the analysis. We now report a method to separate DEC-N-oxide from DEC in plasma using solid phase extraction with subsequent gas chromatographic analysis using a nitrogen specific detector. One-diethylcarbamyl-4-ethylpiperazine (E-DEC) was the internal standard. The standard curve of DEC was linear in the range of 10 to 200 ng/ml as described by Y=0.0350+0.0128X, $R^2=0.999$. The limit of quantitation was 4 ng/mL. Reproducibility at 10, 100 and 200 ng/mL concentration points of the standard curve gave coefficient variations of 6.1%, 7.8% and 1.6%, respectively. The recovery following solid phase extraction was 99.3% for DEC and 94.8% for the internal standard. This sensitive and specific analytical method is suitable for pharmacokinetic studies of DEC.

• Journal of the Korean Chemical Society
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• v.37 no.6
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• pp.585-589
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• 1993

A fluorimetric method for the determination of Fe(Ⅲ) using N,N'-oxalylbis(2-pyridyl-3'-sulphobenzoyl hydrazone)(OPSH) as a emission reagent has been developed. Determination has been performed by measuring the fluorescence intensity of Fe(Ⅲ) complex at 367 nm in aqueous solution (pH 3) with 290 nm excitation. There was a linear relationship between Fe(Ⅲ) concentration and fluorescence intensity over the range 2000∼10 ng/ml. The method has been applied to the determination of Fe(Ⅲ) in synthetic mixtures and tap water