• Clinical and Experimental Pediatrics
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• 제49권6호
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• pp.686-690
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• 2006

심장압전을 동반하는 흉막 및 심낭삼출은 신생아, 특히 극소 저출생체중아에서 흔히 시행되는 제대정맥도관의 드물게 발생하는 치명적인 합병증으로서 신속한 진단과 치료를 요한다. 저자들은 극소저출생체중아에서 제대정맥도관의 합병증으로 발생한 흉막삼출과 심장압전을 동반한 심낭삼출을 흉관삽입과 심낭도관술로 치유한 1례를 경험하고, 아직 국내에는 보고된 적이 없어 문헌고찰과 함께 보고하는 바이다.

• Child Health Nursing Research
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• 제27권4호
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• pp.339-353
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• 2021

Purpose: This study was conducted to investigate the educational needs for practicing neonatal intensive care among Korean nursing students. Methods: An explorative, sequential, mixed-methods design was used. Qualitative content analysis was conducted of in-depth interviews of six nursing students, five clinical practice faculty members, and five nurses in the neonatal intensive care unit. The results of a survey of 174 nursing students were analyzed quantitatively. Results: Nursing students, clinical practice faculty members, and nurses wanted opportunities for direct nursing practice and education in school during neonatal intensive care practice. In terms of specific educational content, nursing students expressed the highest observation-related educational needs for communication with medical team members, and they expressed the highest practice-related educational needs for operating medical equipment used for neonatal intensive care. The nursing students' needs with regard to the method of practice education were highest for orientation from the head nurses. Conclusion: Communication and operating medical equipment were found to be areas with high educational needs for practicing neonatal intensive care among Korean nursing students. Further research is needed to develop an educational framework and setting for practicing neonatal intensive care that would meet their needs.

• Neonatal Medicine
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• 제28권1호
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• pp.59-63
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• 2021

An important, albeit rare, cause of fetal bradycardia is long QT syndrome (LQTS). Congenital LQTS is an ion channelopathy caused by mutations in genes encoding cardiac ion channel proteins. Fetal onset of LQTS imposes high risk of life-threatening tachyarrhythmias and sudden cardiac death. Here, we report the case of a female newborn with fetal onset of bradycardia and a 2:1 atrioventricular (AV) block. After birth, a 12-lead electrocardiogram (ECG) revealed bradycardia with QT prolongation of a corrected QT (QTc) interval of 680 ms and pseudo 2:1 AV block. Genetic testing identified a heterozygous Gly402Ser (c.1204G>A) mutation in CACNA1C, confirming the diagnosis of LQTS type 8 (LQT8). The patient received propranolol at a daily dose of 2 mg/kg. Mexiletine was subsequently administered owing to the sustained prolongation of the QT interval and pseudo 2:1 AV block. One week after mexiletine inception, the ECG still showed QT interval prolongation (QTc, 632 ms), but no AV block was observed. There were no life-threatening tachyarrhythmias in a follow-up period of 13 months.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제24권3호
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• pp.256-264
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• 2021

Purpose: Data on the relationship between gastroesophageal reflux (GER) and brief resolved unexplained events (BRUE) in infants is scarce. The aim of this study was to identify the characteristics of combined multichannel intraluminal impedance-pH (MII-pH) monitoring in infants who have experienced BRUE. Methods: We conducted a prospective study of infants who were hospitalized on account of BRUE and required 24-hour MII-pH monitoring. Results: Twenty-one infants (mean age, 4.7 months; range, 0.9-8.9 months; male/female, 11/10) participated in this study. BRUE symptoms associated with GER were found in 10 infants (47.6%). Based on the RI on pH-metry alone, only 7 (33.3%) infants were diagnosed with GERD. More than 100 GER episodes detected by MII were found in 10 (47.6%) infants. Nineteen percent of infants were diagnosed with GERD based on both pH and MII. Conclusion: Both acid and non-acid reflux seem to play a significant role in the pathogenesis of GER-related BRUE in infants.

• Clinical and Experimental Pediatrics
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• 제45권11호
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• pp.1426-1429
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• 2002

저자들은 재태연령 35주 2일, 출생 체중 2.19 kg으로 출생시 낮은 Apgar score(1/2)와 흉부 촬영상 우측 횡격막 거상을 보였던 환아에서 복부 초음파 검사와 컴퓨터 단층촬영을 시행하여 간 우엽에 생긴 단발성 농양을 발견하였으며 초음파를 이용한 경피적 천자 흡인물 배양 검사에서 포도상 구균이 검출된 선천성 간농양 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• Journal of Genetic Medicine
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• 제17권2호
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• pp.102-107
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• 2020

We report the case of an infant with a 4q35.1 deletion with 10p duplication. This mutation is rarely reported in the literature and has been found to have variable clinical findings, often including developmental delay. In this case, the condition was detected by chromosomal microarray analysis after initial manifestation of a feeding problem and developmental delay. Minor dysmorphic features with abnormal neurological examination led to further evaluation. The father's chromosome complement was 46, XY, t(4;10)(q35;p12.2). Parental balanced translocation can go unrecognized, because affected individuals are often phenotypically healthy until they have fertility issues such as recurrent miscarriages or children with severe congenital disorders. Genetic diagnoses help to establish a clear family genetic background that permits the development of clear treatment strategies. Prenatal counseling can also help to understand the possible risks associated with pregnancy or future child planning.

• Neonatal Medicine
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• 제16권1호
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• pp.85-88
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• 2009

저자들은 우측 다리와 겨드랑이의 협착고리, 우측 발의 만곡족, 척추 측만증, 좌측 엄지 손가락의 다지증, 우측 엄지 손가락 결여증과 더불어, 두피에 피부 무형성증이 동반된 양막대증후근 1례를 경험하였기에 문헌 괓ㄹ과 함께 보고하는 바이다.

• Child Health Nursing Research
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• 제17권4호
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• pp.215-221
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• 2011

Purpose: Newborns routinely experience pain associated with invasive procedures such as blood sampling, venipuncture, heelstick, or venous cannulation. This study was done to provide data for a nursing intervention to alleviate newborn pain clinically by investigating the effect of local anesthetic cream during venipuncture. Methods: Participants were 70 newborns hospitalized in the nursery. Informed Consent was obtained from parents of the newborns. Venipuncture for regular blood sampling was carried out for a test on 2 groups; the experimental, placebo group. The neonatal infant pain scale (NIPS), and duration of crying were measured to assess pain reaction. All neonatal behaviors were recorded on videotape. Results: There were significant differences in pain behavior during venipuncture (t=-4.752, p<.001), immediately after sampling (t=-5.591, p<.001), 3 minutes after puncture (t=-2.469, p=.017), and in duration of crying (t=-3.005, p=.004). Conclusion: Results show that local administration of EMLA cream before venipuncture causes a reduction in neonatal pain response, indicating that the EMLA cream has the effect of pain relief.

• Neonatal Medicine
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• 제18권1호
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• pp.148-152
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• 2011

괴사성 근막염은 급격히 진행되는 심부 연 조직 감염으로 주로 면역 저하나 당뇨를 앓고 있는 성인에서 발병하나 드물게 신생아에서도 생길 수 있으며, 감염 초기에 괴사 조직을 제거하는 수술을 포함한 적절한 치료가 이루어지지 않으면 사망에 이르는 매우 위험한 질환이다. 그러나 증상과 이학적 소견이 비특이적이고 매우 드물게 발생하므로 때로는 진단과 치료가 늦어지기도 한다. 그러므로, 피부 또는 피하 조직 감염 소견을 보이는 모든 환아에게서 항상 심부 조직 감염의 가능성을 염두에 두고 진단적, 치료적 접근이 이루어져야 하겠다. 저자는 생후 7일째인 건강한 만삭 신생아에서 특별한 선행 요인 없이 지역 획득 메티실린 내성 황색포도상 구균에 의해 발생한 괴사성 근막염을 경험하였기에 보고하는 바이다.

• Journal of Preventive Medicine and Public Health
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• 제20권2호
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• pp.322-330
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• 1987

출생시 체중변화의 양상과 산모의 연령 및 출산순위와의 관계를 알아보기 위하여 1977년 1월부터 1986년 12월까지 부산시내 1개 종합병원에서 총 14,346건의 분만 가운데 20주이후에 출생한 단태아 13,634명을 대상으로 산실의 분만대장에서 신생아의 출생순위분포, 산모의 연령분포, 신생아의 체중분포와 평균체중, 산모의 연령과 출산순위에 따른 저 체중아와 과체중아의 출생을, 유산경험율과 사산율을 조사하였다. 신생아의 평균체중은 1979년에는 남아 3074gm, 여아 2985gm에서 1986년에는 남아 3266gm, 여아 3210gm 으로 증가하였고, 저체중아의 발생율은 1977년 7.2%에서 점차 증가하여 1980년에는 10.4%였으나 그후 점점 감소하여 1986년에는 6.5%였다. 과체중아의 발생율은 2,9%에서 4.6%사이로 평균 3.9%였으며 특별한 변화 양상은 볼 수 없었다. 유산을 경험 한 산모의 비율은 1979년에 51.6%에서 1986년에는 45.1%로 감소하였고, 사산율도 1977년에는 2.6%에서 1986년에는 1.5%로 감소했다. 이와같은 변화에는 가족계획 실천율의 증가와 결혼연령의 상승으로 $25{\sim}34$세사이 산모의 1과 2순위 출생아가 차지하는 비율이 증가한 것이 크게 영향을 미친 것으로 생각되며, 과체중아의 비율은 늘지 않고 오히려 저체중아의 출생율은 감소되어 전체적으로 신생아의 건강이 향상되고 있는 것으로 나타났다.