• Therapeutic Science for Rehabilitation
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• v.10 no.2
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• pp.129-140
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• 2021

Objective : The purpose of this study was to examine differences in social maturity and behavioral problems according to the level of sleep problems in children with ASD. Methods : The participants were 102 mothers of infants with ASD aged 1-5 years. The Social Maturity Scales (SMS) and Child Behavior Checklist 1.5-5 were used as the measuring tools. Results : The level of sleep problems in infants with ASD was 56.58T on the sleep problems scale. The participants were grouped based on scores on the sleep problems scale: those with scores <65 (good sleepers) or scores ≥65 (poor sleepers). Sleep problems significantly correlated with all the scales on the CBCL. However, no association was found between sleep problems and social quotients. Poor sleepers achieved significantly lower scores on the social quotient scale of the SMS than good sleepers. Poor sleepers achieved significantly higher scores in internalizing problems, externalizing problems, and DSM-oriented scales on the CBCL compared to those in the good sleepers. Conclusion : The significance of this study is that it has verified the severity of sleep problems in infants with ASD and has examined the differences in social maturity and behavioral problems between poor sleepers and good sleepers.

• Therapeutic Science for Rehabilitation
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• v.8 no.2
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• pp.67-78
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• 2019

Objective : The purpose of this study was to investigate the effect of hand tapping on the accuracy and the fluency of speech production in children with speech sound disorder(SSD) and their typically developing peers(TD). Methods : The study subjects were 15 SSD children and 15 TD children aged 4, 5, and 6 years of age. Subjects were asked to give a picture name without hand tapping in the first experimental condition, and with hand tapping in the second experiment condition. Results : The results showed that hand tapping significantly increased disfluency in TD, whereas in SSD. it did not affect the accuracy or fluency of speech production. In addition, TD demonstrated a significant positive correlation with the changes of accuracy and disfluency due to hand tapping, whereas SSD had no correlation. Conclusion : We discussed the possibility that hand tapping could serve as an obstacle distracting attention from SSD and TD, acting as a motor gesture to facilitate phonological processing when facing the difficulty in lexical retrieval for SSD.

• Therapeutic Science for Rehabilitation
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• v.10 no.4
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• pp.81-94
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• 2021

Objective : Response time plays a prominent part in research on cognitive ability and the aging effect. This study aimed to identify the impact of cognitive ability on information processing by conducting cognitive response time (CRT) using a computer program. Methods : This study was conducted in 30 normal elderly (NE) and 30 elderly with amnestic MCI (aMCI), aged 65-79 years old living in Daegu and Gyeongbuk. The results were analyzed using the statistical analysis program R 4.0.2 (University of Auckland, New Zealand). Results : In the three sub-areas of CRT, the total response time showed a significant difference depending on group or age, and the error rate showed a significant difference depending on age or group in some sub-areas. In the aMCI group, the performance of CRT significantly correlated with that of the overall cognition and memory test. Conclusion : Information processing depending on aging or cognitive ability and the differential performance of processing speed could be observed through CRT. The performance of this test was found to be significantly correlated with that of the overall cognition and memory test. Therefore, CRT could be used meaningfully as a simplified tool to predict the initial cognitive disorder of the elderly in the community.

• Therapeutic Science for Rehabilitation
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• v.12 no.4
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• pp.39-51
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• 2023

Objective : This study seeks to unveil the intellectual framework of research surrounding children's occupations by utilizing social network analysis of keywords from studies focused on childhood. Methods : From August 2003 to August 2023, we analyzed 3,364 keywords extracted from 270 research articles in the Korean Citation Index with the keyword "Child and Occupation" using the NetMiner program. Results : Research on children's work has increased quantitatively over the past decade. Keywords exhibiting a high degree of centrality in the realm of child occupation research included Task (0.055), Group therapy (0.040), Working memory (0.037), Intervention (0.033), Performance (0.030), Language (0.026), Ability (0.026), Skill (0.024), and Program (0.023). Notably, the weighted terms in the Word Network included Evaluation-Tool (30), School-Student (15), and Activity-Participation (15). The primary keywords from each topic in topic modeling were Activity (0.295), Disability (0.604), Education (0.356), Skill (0.478), School (0.317), Function (0.462), Disorder (0.324), Language (0.310), Comprehension (0.412), and Training (0.511). Conclusion : This study describes the trends in the domestic field of pediatric occupational research. These efforts provided valuable insights into pediatric occupational therapy in South Korea.

• Journal of Biomedical Engineering Research
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• v.37 no.1
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• pp.15-20
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• 2016

Essential tremor is a neurological disorder with a tremor of the arms and hands. It is well known that essential tremor is characterized by the postural tremor and the action tremor. There has been no report on the quantitative difference in the characteristics of two tremor types. The purpose of this study was to investigate the possible difference in tremor characteristics of postural and action tremors. Seventeen patients with essential tremor ($68.9{\pm}7.9years$, 7 men, 10 women) participated in this study. Patients performed the tasks of postural maintenance (arms outstretched) and daily actions (spiral drawing). Three-axes (pitch, roll and yaw) gyro sensors were attached on index finger, back of hand and forearm, from which the segment and the joint angular velocities were calculated. Outcome measure was the tremor amplitude defined as the root-mean-square mean of the vector-sum angular velocity at segments and joints. Two-way ANOVA showed that task and joint had main factor on the tremor amplitude (p < 0.05). Post-hoc analysis revealed that tremor amplitude at the metacarpo-phalangeal joint was not affected by task (p > 0.05). However, tremor amplitude at the wrist joint differed among the tasks (p < 0.05), and it was greater in the action tasks than in postural task. Tremor was greater at finger segments than at hand and forearm and it increased in action tasks. The results of this study would be helpful for the understanding and task-specific treatments of the essential tremor.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.20 no.1
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• pp.141-148
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• 2020

Unilateral neglect is associated with stroke, a neurological disorder caused by cerebrovascular injury, and is a symptom of not recognizing or responding to the opposite stimulus of the cerebral hemisphere, mainly in the right cerebral hemisphere injury. In this paper, we implemented contents using Virtual Reality based on 10 items and contents of Korean Catherine Bergego Scale(K-CBS), which is used as a behavioral evaluation scale for unilateral neglect. Implemented contents can evaluate body disregard, motility disregard, visual and spatial disregard, auditory attention, etc., which are symptoms of unilateral neglected patients, and can confirmed progression of disease quantitatively by measuring time and rotation angle of head during visual recognition. This method is expected to be useful for rehabilitation training using convenient unilateral neglect diagnosis and its applied contents.

• PNF and Movement
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• v.16 no.2
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• pp.287-294
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• 2018

Purpose: The neurodynamic test used to implicate symptoms arising from the nerve is proposed to selectively increase the strain of the nerve without increasing the strain of adjacent tissue, although this has not yet been established in the time of nerve tension application. This study aimed to investigate the acute effects of nerve stretching time on nerve excitability using compound nerve action potential (CNAP) analysis. Methods: Thirty healthy young adults (mean age=23.10 years) with no medical history of neurological or musculoskeletal disorder voluntarily participated in this study. Nerve excitability was assessed using the median nerve conduction velocity test. The amplitude of the CNAP was measured under three conditions: resting phase (supra-maximal stimulus, without nerve stretching), baseline phase (two-thirds of the supra-maximal stimulus, without nerve stretching), and stretch phase (two-thirds of the supra-maximal stimulus, with 1-5 minutes nerve stretching). One-way repeated measures ANOVA was conducted to compare the latency and amplitude of CNAP. A post-hoc test was analyzed using the contrast test. Results: The latency was significantly delayed after 1 min. of nerve stretching in comparison with the baseline test. However, no significant difference was found during the nerve stretching (1-5 min.). The amplitude was significantly increased by nerve stretching. Conclusion: Nerve stretching can induce nerve excitability without any nerve injury. Based on the results, more than 1 min. of nerve stretching as a neurodynamic test can be a useful method in the clinical setting.

• Tuberculosis and Respiratory Diseases
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• v.70 no.2
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• pp.160-164
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• 2011

Paraneoplastic neurologic syndrome is a group of assorted disorders resulting from damage to the nervous system in cancer, remote from primary site, and not related to metastasis, infection, or metabolic disorder associated with cancer. Patient with small cell lung cancer sometimes shows various neurological syndromes, but patient with non-small cell lung cancer rarely shows neurologic syndromes and few antineuronal antibodies have been found. Here, we report a case of 53-year-old male patient who developed ptosis and extraocular muscular limitation of left eye due to third and forth cranial nerve palsy in non-small cell lung cancer without brain metastasis. These neurologic symptoms improved after lobectomy without any other treatment immunotherapy.

• Annals of Clinical Neurophysiology
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• v.4 no.2
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• pp.133-136
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• 2002

Dyskinesia can occur as a neurological abnormality due to stroke, and its incidence in stroke patients is reported to be about 1%. It is possible to classify dyskinesia into one of the morphologic types already classified clinically. However, a specific type of dyskinesia can occur; one which does not fall into the existing morphologic types. We experienced such a case of specific type dyskinesia, which couldn't be classified into the existing classification system. A 50-year-old man visited our hospital due to rhythmic dyskinesia of the right hand, which appeared during the resting state, and had developed one month after left subcortical infarction. Flexion and extension movements of the fingers at 3Hz appeared due to the impatient impulse to move. However, this abnormal movement could be easily suppressed under the patients will. We suggested that the abnormal movement was similar to akathisia from the fact that it occurred due to the internal desire to move and that the patient could suppress dyskinesia. However, the rhythmic tendency and lack of medication history of antipsychotics suggested that the movement was not the typical form of akathisia. The present case may represent a new clinical type of movement disorder developed after stroke. Considering the clinical pattern of the present case and following a review of the literature, we believe that it can be labeled, post-stroke rhythmic akathisia.

• Journal of Genetic Medicine
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• v.2 no.1
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• pp.17-22
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• 1998

The Lesch-Nyhan syndrome which is caused by the deficiency of hypoxanthine guanine phosphoribosyltransferase is an X-linked recessive disorder characterized by hyperuricemia, choreoathetosis, mental retardation and compulsive self-injurious behavior. Clinical management of the patients with the Lesch-Nyhan syndrome is frustrating and requires burdensome medical treatment since it cripples the patient and shortens the life span by progression of neurological symptoms, but there are no cures or measures for relieving relentless natural course of the disease yet. Therefore, prenatal diagnosis of the affected fetus is important in genetic counselling for the family at high risk. In this study, four different mutations in the HPRT gene of four probands have been identified in four unrelated families; K215X, Q109X, nt.631 ${\Delta}A$, and nt.289 ${\Delta}GT$. Two mutations among them altered restriction enzyme sites; SpeI for Q109X and MaeI for nt.289 ${\Delta}GT$. Based on their molecular defects, prenatal diagnoses of 3 the fetuses were successfully made between ninth and eleventh week of gestation by polymerase chain reaction (PCR), restriction digestion and DNA sequencing using cDNA obtained from chorionic villus samples (CVS). We predicted the outcome of all fetuses prenatally. Among the three fetuses two were male and one was female according to the identification made by PCR amplification of the sex determining region of the Y chromosome(SRY) gene. Each carried a wild type allele for the corresponding mutant allele. They were also tested postnatally for the mutations to be unaffected.