• Title/Summary/Keyword: Neuroendocrine

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Distribution and Characteristics of Pulmonary Neuroendocrine Tumors: Single Institution Experience in Lebanon

  • Kesrouani, Carole;Ghorra, Claude;Rassy, Marc;Kourie, Hampig Raphael;Kattan, Joseph
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.5
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    • pp.2579-2581
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    • 2016
  • Background: Neuroendocrine tumors represent 20% of primary lung neoplasms in some registries. According to the WHO classification of 2004, reconsidered for 2015, these lung tumors are divided into 4 groups: typical and atypical carcinoid, small cell and large cell neuroendocrine carcinomas. We report in this paper, for the first time in Lebanon, the distribution and the population characteristics of these tumors. Materials and Methods: This descriptive retrospective study concerned all the pulmonary neuroendocrine tumors (NET) with their characteristics diagnosed in $H\hat{o}tel$ Dieu de France in Beirut, Lebanon from 2001 to 2012, with attention to features like age, gender and subgroup. Results: Of 194 patients with pulmonary NET, 12.4% were typical carcinoid tumors, 3.6% atypical carcinoid, 66.5% small cell lung cancer, 7.7% combined small cell carcinomas and 9.8% large cell neuroendocrine tumors. The mean ages of patients were respectively 51.2 years in typical carcinoid, 64 years in atypical carcinoid, 64.2 years in small cell lung cancers, 67.2 in combined small cell lung cancer and 66.9 in large cells neuroendocrine tumors. The M/F sex ratios were respectively 0.3, 1.3, 1.4, 2.7 and 2.2. Conclusions: The characteristics of lung neuroendocrine tumors in our Lebanese institution are comparable to those reported in the literature.

Pulmonary Large Cell Neuroendocrine Carcinoma -One Case Report- (폐의 대세포 신경내분비암 -1례 보고-)

  • 이석열;송철민;조현득;박형주;이철세;이길노
    • Journal of Chest Surgery
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    • v.35 no.12
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    • pp.906-908
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    • 2002
  • A 60-year-old male was admitted to our hospital complaining of general weakness. Chest radiography showed lung mass on left lower lobe. After left lower lobectomy and mediastinal lymph node dissection, The mass was pathologically diagnosed as large cell neuroendocrine carcinoma. Pulmonary large cell neuroendocrine carcinoma is rare. Herein we report a case of large cell neuroendocrine carcinoma in lung.

Thymic Neuroendocrine Tumor (흉선의 신경내분비 종양)

  • 이응배;이상철;박태인;조준용;장봉현;이종태;김규태
    • Journal of Chest Surgery
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    • v.35 no.4
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    • pp.325-328
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    • 2002
  • The neuroendocrine tumor is a rare thymic neoplasm, which has been regarded as a distinct tumor from thymoma and originates from Kultschizky cell. The pathologic diagnosis of thymic neuroendocrine tumor has been on findings from light microscopy, immunohistochemical studies, and electron microscopy. About 50% of thymic carcinoids are seen with endocrinopathies. Recurrence and extrathoracic metastasis are characteristics of thymic carcinoids. Surgical removal of the initial and recurred tumor is considered to be the most effective treatment. The role of the adjuvant chemotherapy and radiotherapy is still uncertain. Herein we report a case of thymic neuroendocrine tumor, which was resected surgically.

Large Cell Neuroendocrine Carcinoma of the Lung -A Case Report- (대세포 신경내분비암 -1례 보고-)

  • 김영진;김범경
    • Journal of Chest Surgery
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    • v.35 no.4
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    • pp.311-314
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    • 2002
  • A 48-year-old man whose symptom had intermittent right chest pain and x-ray film revealed large mass on right mid lung fields was examined. A conclusive histological diagnosis of large cell neuroendocrine carcinoma was made following bilobectomy. Large cell neuroendocrine carcinoma is an uncommon pulmonary neoplasm, which is characterized by large cell size and low nuclear to cytoplasmic. This tumor shows prominent organoid nests of tumor cells with peripheral palisading and rosette-like structures. We experienced one case of large cell neuroendocrine carcinoma of lung and report it with references.