• Journal of Magnetics
• /
• v.17 no.2
• /
• pp.133-137
• /
• 2012

We investigated the effects of pulsed magnetic fields (PMF) stimulus on electroencephalogram (EEG) alpha activity and heart rate variability (HRV) from electrocardiogram (ECG) measurements with various stimulus durations at acupoint PC9. The alpha activity in the EEG and the ratio of low frequency power and high frequency power (LHR) in the HRV, a reflection of sympathovagal activity, were increased and decreased, respectively, after PMF stimulus of 3 min. Our spectral analysis quantitatively proved that the changes in the EEG alpha activity were consistent with an autonomic function in the ECG. These findings suggest that appropriate PMF stimulus results in the same effect as that of acupuncture applied to the acupoint PC9, which is closely related to the parasympathetic activity of the autonomic nervous system.

• Advances in Traditional Medicine
• /
• v.8 no.4
• /
• pp.448-451
• /
• 2008

Picrorhiza kurrooa Royle. is a well known medicinal plant among the indigenous medical practitioners of India. Present study is the first time to report the activity on the central nervous system. Preliminary study of the hot water extract showed significant depressant activity on the hole board test as evidenced from the ambulation and head dipping scores. The extract showed better activity compared to diazepam on the duration of pentobarbital induced sleeping time.

• BMB Reports
• /
• v.35 no.1
• /
• pp.94-105
• /
• 2002

Apoptotic cell death is a fundamental and highly regulated biological process in which a cell is instructed to actively participate in its own demise. This process of cellular suicide is activated by developmental and environmental cues and normally plays an essential role in eliminating superfluous, damaged, and senescent cells of many tissue types. In recent years, a number of experimental studies have provided evidence of widespread neuronal and glial apoptosis following injury to the central nervous system (CNS). These studies indicate that injury-induced apoptosis can be detected from hours to days following injury and may contribute to neurological dysfunction. Given these findings, understanding the biochemical signaling events controlling apoptosis is a first step towards developing therapeutic agents that target this cell death process. This review will focus on molecular cell death pathways that are responsible for generating the apoptotic phenotype. It will also summarize what is currently known about the apoptotic signals that are activated in the injured CNS, and what potential strategies might be pursued to reduce this cell death process as a means to promote functional recovery.

• Journal of Genetic Medicine
• /
• v.11 no.1
• /
• pp.11-15
• /
• 2014

Congenital central hypoventilation syndrome (CCHS) is a disorder of the autonomic nervous system characterized by a decreased response to hypercarbia. CCHS is frequently associated with congenital megacolon; the combination is called Haddad syndrome. CCHS is associated with dysfunction in respiratory features of the autonomic nervous system and with other disorders, including facial deformities, cardiovascular symptoms, and tumors. Patients with CCHS frequently have a mutation in the homeobox protein 2b (PHOX2B) gene. Most mutations involve heterozygous expansion of alanine repeats (GCN). Interestingly, a higher polyalanine repeat number is associated with a more severe clinical phenotype. To clarify the role of PHOX2B in disease pathogenesis, we introduce and review the clinical and molecular features of CCHS and Haddad syndrome.

• Proceedings of the KSME Conference
• /
• 2003.04a
• /
• pp.935-939
• /
• 2003

The emotion recognition is one of the most significant interface technologies which make the high level of human-machine communication possible. The central nervous system stimulated by emotional stimuli affects the autonomous nervous system like a heart, blood vessel, endocrine organs, and so on. Therefore bio-signals like HRV, ECG and EEG can reflect one' emotional state. This study investigates the correlation between emotional states and bio-signals to realize the emotion recognition. This study also covers classification of human emotional states, selection of the effective bio-signal and signal processing. The experimental results presented in this paper show possibility of the emotion recognition.

• Proceedings of the KSPS conference
• /
• 2007.05a
• /
• pp.146-148
• /
• 2007

Studies of cry characteristics in the newborn infant were aimed to determine if cry analysis could be succesful in the early detection of the infant at risk for developmental difficulties. Crying presupposes functioning of the respiratory, laryngeal and supralaryngeal muscles. The nervous system controls the capacity, stability, and co-ordination of the movements in these muscles. Hence, the cry provides information about how the Nervous System is functioning. 3 patients(down syndrome, cornelia de lange syndrome, Patent ductus arteriosus) were assessed through a Computerized Speech Lab (CSL). Tests had been chosen to assess Fundamental frequency(mean, maximum, minimum values), Melody contour, NHR, Energy. We compared the data from patients and healthy volunteer. Variations in cry characteristics were documented in a number of medical abnormalities.

• Advances in Traditional Medicine
• /
• v.6 no.3
• /
• pp.215-220
• /
• 2006

The Sundarbans mangrove forest has a rich biodiversity of flowering plants and many of these have been used in traditional medicine although the flora remains comparatively uninvestigated scientifically. Xylocarpus granatum, Xylocarpus moluccensis and Excoecaria agallocha methanolic extract showed a central nervous system depressant activity on the hole cross and open field test at 800 mg/kg dose level. The most significant depressant activity was observed in Xylocarpus granatum followed by Xylocarpus moluccensis and Excoecaria agallocha. There was no depressant activity observed in the models for Sarcolobus globosus. Further studies are required to confirm the activity and to explain the mechanism.

• YAKHAK HOEJI
• /
• v.30 no.6
• /
• pp.334-342
• /
• 1986

The relationship between the maintenance of hypertension and the central noradrenergic nervous system activity in spontaneously hypertensive rats (SHR) was studied. The norepinephrine turnover rates in 5 brain areas; telencephalon, hypothalamus/thalamus, midbrain, pons/medulla, cerebellum as a measure of noradrenergic neuronal activity were measured at the ages of 14 weeks in SHR and normotensive Wistar rats. In 14-week old SHR, blood pressure was significantly higher than in normotensive rat, and central norepinephrine turnover rates were significantly greater in telencephalon, hypothalamus/thalamus, midbrain. There were no differences between norepinephrine turnover rates in pons/medulla, cerebellum of SHR and those of normotensive rats.

• Journal of Chest Surgery
• /
• v.50 no.2
• /
• pp.130-132
• /
• 2017

Harlequin syndrome is a rare disorder of the sympathetic nervous system characterized by unilateral facial flushing and sweating. Although its etiology is unknown, this syndrome appears to be a dysfunction of the autonomic nervous system. To the best of our knowledge, thus far, very few reports on perioperative Harlequin syndrome after thoracic surgery have been published in the thoracic surgical literature. Here, we present the case of a 6-year-old patient who developed this unusual syndrome following the resection of a posterior mediastinal mass.

• Journal of Environmental Science International
• /
• v.21 no.5
• /
• pp.605-611
• /
• 2012

The purpose of this study is to analyze psychological and physiological effects accordance with viewing and walking in the forest and urban area. In the result of measurement of physiological reactions in nervous system, viewing of the forest had a calming effect on the nervous system by reducing blood pressure and heart rate. The other hand, viewing and walking in the urban area compared to the forest area raised stress by increasing blood pressure and heart rate. In addition, viewing in forest area was effective in stress relief by noticeable reduction of the amylase concentration. In contrast, walking in the urban area was also confirmed an increase of stress by increasing the concentration of the amylase. A viewing and walking in forest area was effective in alleviating depressed on anxiety, anger, fatigue and confusion.