• 제목/요약/키워드: Negative chronotropic and ionotropic effects

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Toxicity and Biological Activity of Extracts from Stichopus japonicus

  • Lee, Sang-Joa;Shin, Jai-Mu;Im, Byung-Uk;Kim, Yong-Hae
    • Archives of Pharmacal Research
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    • 제7권1호
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    • pp.61-62
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    • 1984
  • The toxicity of water extracts from intestine parts (digestive tract respiratory tree) of Korean Stichopus japonicus was determined using mouse units and more purified substance decreases the amplitude of contraction of guinia pig atria in vitro; showes negative chronotropic and ionotropic effects in the spontaneously beating guinea pig atria.

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