• 제목/요약/키워드: Negative Selection

검색결과 592건 처리시간 0.032초

실버세대의 주관적 건강인식도와 외식선택속성의 위계적 회귀분석에 관한 연구 (Hierarchical Regression Analysis of Subjective Health Perception and Eating-out Selection Attributes of Elderly People)

  • 김보람;묵영임;윤지영;주나미
    • 대한영양사협회학술지
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    • 제25권3호
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    • pp.188-198
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    • 2019
  • This study examined the subjective health recognition, motivation, selection property, consumption realties, and generalities of elderly people eating out. The ratio of women eating out in those over 60 years of ages was high and people in that age group ate out most actively. The score of convenience-oriented, gourmet-oriented, and dignity-oriented of the selection property for eating out increased with increasing frequency and expenditure for eating out. With increasing age, a negative (-) relationship with a decrease in the safety-oriented score of the selection property for eating out was predicted. As the number of days eating out increased, a positive (+) relationship with an increase in the safety-oriented score of the selection property for eating out was observed. As the scores of physical and social health perception increased, a positive (+) relationship with an increase in the gourmet oriented score was observed. Based on the results, various research on the relationship between the health recognition and eating out behavior of those over 60 years of age are required.

벤처기업 최고 경영자 경험 특성과 여유자원이 전략적 제휴 유형 선택에 미치는 영향 (The Effect of CEO Experiential Attributes and Slack Resource on the Selection of Strategic Alliance Type)

  • 한상연
    • 벤처창업연구
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    • 제17권1호
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    • pp.45-61
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    • 2022
  • 본 연구는 기업이 전략적 경영활동으로 추진하는 전략적 제휴의 유형 선택에 최고 경영자의 경험특성과 기업이 보유한 여유자원이 미치는 영향을 실증 분석하였다. 이는 단순히 경쟁우위 확보와 성과향상을 위하여 기업이 추진하는 전략적 제휴의 결정요인을 규명하는 것을 넘어 제휴의 유형을 구분하고 이러한 전략적 선택에 영향을 미치는 요소들을 규명하는 것을 목적으로 한다. 이에 따라 본 연구는 2020년 벤처기업정밀실태조사 자료를 활용하여 로지스틱 다중회귀 분석을 실시하였다. 분석결과 벤처기업 최고 경영자의 학력 수준이 높고, 대기업 근무 경험을 가진 경우 탐색적 유형의 제휴를 추진하는 것으로 나타났다. 반면, 최고 경영자가 가진 과거 창업 경험은 전략적 제휴 유형 선택에 유의미한 영향을 미치지 못하는 것으로 나타났다. 벤처기업이 보유한 여유 자원 중에서는 활용가능여유와 잠재여유가 많을수록 탐색적 제휴에 긍정적 영향을 미치는 것으로 나타났다. 또한, 회복가능여유는 탐색적 제휴에 부정적 영향을 미치는 것으로 나타났으나, 활용적 제휴에는 유의미한 영향을 미치지 못하는 것으로 분석되었다. 본 연구는 학술적 측면에서 전략적 제휴와 관련한 논의를 최고경영자이론 및 여유자원과 연계하여 변수의 영향력을 검증함에 따라 이론적 논의를 확장하는데 기여하였다. 또한, 정책적 측면에서 벤처기업을 위한 개방형 혁신활동 지원정책 수립 및 운영과정에서 기업이 보유한 여유 자원의 유형별 수준이 고려되는 경우 보다 정책효과성을 제고할 수 있다는 시사점을 제공한다.

GENOTYPIC AND PHENOTYPIC CORRELATIONS IN A SOYBEAN CROSS

  • 권신한
    • 한국작물학회지
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    • 제1권1호
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    • pp.42-45
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    • 1963
  • In a plant breeding program, an efficient selection of desired characters in a population is important. Generally, many agronomic characters in a given population are determined by polygenes and quantitatively inherited. In practice, the genetic relationship between two observed characters which are undoubtedly subjected to the environmental influence is difficult to identify. In recent years, many workers have attempted to understant the genetic relationship between characters in terms of genotypic correlation, and the knowledge thus gained should furnish many important and useful information for the planning of breeding, selection, and interpretation of the result. The genotypic correlation is the result of pleiotropy, linkage of genes(2, 3, 5, 6, 8) and natural or artificial selection(4). The purposes of this study were to estimate genotyric and phenotypic correlations between all possible pairs of nine characters. and to seek certain characters which may be useful as indicators of certain important agronomic characters. Weber and Moorthy(10), Johnson et al. (5) and Sheth(7) found that in general, the genotypic correlations were higher than the phenotypic correlations. Weiss et al. (11) obtained significant positive correlations between maturity and oil content, maturity and low protein content, and high protein content and low oil content. Weber and Moorthy(10) reported the positive genotypic correlations between flowering and maturity, yield and maturity, yield and plant height, yield and seed weight, and negative genotypic correlations between maturity and oil content, and oil content and seed weight. Johnson et al. (5) studied the genotypic and phenotypic correlations among 24 characters and concluded that selection based entirely on a long fruiting period, lateness, heavy seed, low protein, high oil and resistance to lodging would be effective in increasing yield. Sheth(7) found the following positive associations among characters; height and maturity, yield and lodging, low protein content and high oil content, and yield and low protein content. Hanson et al.(1) also reported high negative correlation between seed yield and protein content.

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Genetic Parameters and Responses in Growth and Body Composition Traits of Pigs Measured under Group Housing and Ad libitum Feeding from Lines Selected for Growth Rate on a Fixed Ration

  • Nguyen, Nguyen Hong;McPhee, C.P.
    • Asian-Australasian Journal of Animal Sciences
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    • 제18권8호
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    • pp.1075-1079
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    • 2005
  • The main objective of this study is to examine genetic changes in growth rate and carcass composition traits in group housed, ad libitum fed pigs, from lines of Large White divergently selected over four years for high and low post-weaning daily gain on a fixed but restricted ration. Genetic parameters for production and carcass traits were also estimated by using average information-restricted maximum likelihood applied to a multivariate individual animal model. All analyses were carried out on 1,728 records of group housed ad libitum fed pigs, and include a full pedigree of 5,324 animals. Estimates of heritability (standard errors in parentheses) were 0.11 (0.04) for lifetime daily liveweight gain (LDG), 0.13 (0.04) for daily carcass weight gain (CDG) and 0.28 (0.06) for carcass backfat (CFT). Genetic correlations between LDG and CDG were highly positive and between LDG and CFT negative, suggesting that selection for lifetime daily gain under commercial conditions of group housing with ad libitum feeding would result in favourable improvement in carcass traits. CFT showed negative genetic correlations with CDG. Correlated genetic responses evaluated as estimated breeding values (EBVs) were obtained from a multivariate animal model-best linear unbiased prediction analysis. After four years of divergent selection for 6 week post-weaning growth rate on restricted feeding, pigs performance tested on ad libitum feeding in groups exhibited changes in EBVs of 6.77 and -9.93 (g/d) for LDG, 4.25 and -7.08 (g/d) for CDG, and -1.42 and 1.55 (mm) for CFT, in the high and low lines, respectively. It is concluded that selection for growth rate on restricted feeding would significantly improve genetic performance and carcass composition of their descendants when group housed and ad libitum fed as is a common commercial practice.

Genetic Diversity of a Natural Population of Apple stem pitting virus Isolated from Apple in Korea

  • Yoon, Ju Yeon;Joa, Jae Ho;Choi, Kyung San;Do, Ki Seck;Lim, Han Cheol;Chung, Bong Nam
    • The Plant Pathology Journal
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    • 제30권2호
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    • pp.195-199
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    • 2014
  • Apple stem pitting virus (ASPV), of the Foveavirus genus in the family Betaflexiviridae, is one of the most common viruses of apple and pear trees. To examine variability of the coat protein (CP) gene from ASPV, eight isolates originating from 251 apple trees, which were collected from 22 apple orchards located in intensive apple growing areas of the North Gyeongsang and North Jeolla Provinces in Korea, were sequenced and compared. The nucleotide sequence identity of the CP gene of eight ASPV isolates ranged from 77.0 to 97.0%, while the amino acid sequence identity ranged from 87.7 to 98.5%. The N-terminal region of the viral CP gene was highly variable, whereas the C-terminal region was conserved. Genetic algorithm recombination detection (GARD) and single breakpoint recombination (SBP) analyses identified base substitutions between eight ASPV isolates at positions 54 and 57 and position 771, respectively. GABranch analysis was used to determine whether the eight isolates evolved due to positive selection. All values in the GABranch analysis showed a ratio of substitution rates at non-synonymous and synonymous sites (dNS/dS) below 1, suggestive of strong negative selection forces during ASPV CP history. Although negative selection dominated CP evolution in the eight ASPV isolates, SLAC and FEL tests identified four possible positive selection sites at codons 10, 22, 102, and 158. This is the first study of the ASPV genome in Korea.

녹차 소비자의 선택속성과 만족이 충성도에 미치는 영향 연구: 관여도의 조절효과 (A Study on the Structural Relationships among Selection Attributes, Satisfaction, and Loyalty of Green Tea Consumers: The Moderating Effect of Involvement)

  • 김경희;한영숙
    • 한국식품조리과학회지
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    • 제27권2호
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    • pp.83-94
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    • 2011
  • The purpose of this study was to analyze the structural relationships among selection attributes, satisfaction, and loyalty of green tea consumers, including their moderating effect of involvement. Questionnaires were administered to residents of Seoul and Gyeonggi-do province, who were 20 years old and older and who had purchased green tea. A total of 700 questionnaires were distributed, and 658 were finally used in the analysis. SPSS 15.0 and LISREL 8.80 were used for the analysis. Selection attributes had a significant effect on satisfaction, and statistical significance was observed with regard to factors such as marketing, production, sensory evaluation, and brand. No significant direct effect was observed between selection attributes and loyalty. Additionally, satisfaction had a significant effect on loyalty. The marketing factor had a negative effect on satisfaction in both the low- and high-involvement groups. The brand factor had a positive effect on satisfaction in the low involvement group, suggesting that developing and promoting a popular brand is essential. Sensory and utility factors had a positive effect on satisfaction in the high involvement group.

Genetic Improvement of Some Traits in Four Strains of Silkworm, Bombyx mori L.

  • Moghaddam S. H. Hosseini;Jomeh K. N. Emam;Mirhosseini S. Z.;Gholamy M. R.
    • International Journal of Industrial Entomology and Biomaterials
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    • 제10권2호
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    • pp.95-99
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    • 2005
  • A breeding plan was carried out on four commercial strains of silkworm (Bombyx mori L.) 101, 102, 103 and 104 to improve some important traits. Genetic gain or response to selection $({\Delta}G)$, heritability of cocoon shell weight (CSW) and specific combining ability effects were estimated to determine the strains that can be improved. Strain 101 had lowest heritabitity, ${\Delta}G$ and viability. Strain 102 was acceptable in selection response but its viability was low. Therefore these two strains were not suitable for more selection. As a result, only lines 103 and 104 were chosen for further improvement. Intra population selection based on independent culling level method practiced from third to sixth generation for both productive and viability traits simultaneously. While CSW and CW had increasingly enhanced during primary generations, they went slightly up after third generation. According to negative genetic correlation, viability decreased during primary generations, but after third generation that paid attention to balanced development of both productive and viability traits, viability increased so that the pupation rate reached to $91\%$ in 103 and $97\%$ in 104 for last generation $(G_8)$.

Optimized Serological Isolation of Lung-Cancer-associated Antigens from a Yeast Surface-expressed cDNA Library

  • Kim, Min-Soo;Choi, Hye-Young;Choi, Yong-Soo;Kim, Jhin-Gook;Kim, Yong-Sung
    • Journal of Microbiology and Biotechnology
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    • 제17권6호
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    • pp.993-1001
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    • 2007
  • The technique of serological analysis of antigens by recombinant cDNA expression library (SEREX) uses autologous patient sera as a screening probe to isolate tumor-associated antigens for various tumor types. Isolation of tumor-associated antigens that are specifically reactive with patient sera, but not with normal sera, is important to avoid false-positive and autoimmunogenic antigens for the cancer immunotherapy. Here, we describe a selection methodology to isolate patient sera-specific antigens from a yeast surface-expressed cDNA library constructed from 15 patient lung tissues with non-small cell lung cancer (NSCLC). Several rounds of positive selection using patient sera alone as a screening probe isolated clones exhibiting comparable reactivity with both patient and normal sera. However, the combination of negative selection with allogeneic normal sera to remove antigens reactive with normal sera and subsequent positive selection with patient sera efficiently enriched patient sera-specific antigens. Using the selection methodology described here, we isolated 3 known and 5 unknown proteins, which have not been isolated previously, but and potentially associated with NSCLC.

Comparison of Breeding System Between Single Population and Two Sub-population Scheme by Computer Simulation I. Equal genetic level for Sub-populations

  • Oikawa, T.;Matsura, Y.;Sato, K.
    • Asian-Australasian Journal of Animal Sciences
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    • 제10권4호
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    • pp.422-427
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    • 1997
  • Breeding efficiency was investigated to reveal crucial factors for constructing effective breeding system with subdivided populations under equal genetic level. Simulation study of selection experiment was performed for 20 generations with 20 replications each, comparing average breeding values and inbreeding coefficients between the two breeding systems; single population scheme and two population scheme, each of which had the same genetic parameters. Genetic correlations (-0.5 to 0.5) were assumed to be caused only by pleiotropic effect of a gene. Phenotypes of the two traits generated by polygenic effect with additive 36 loci and residuals distributed normally were selected by two traits selection index procedure. Comparing between the single population scheme and the two population scheme, the single population scheme showed higher genetic gain with lower inbreeding coefficient. This result was confirmed particularly for the situation of high selection intensity, high heritability and high degree of unevenness for economic weight. Genetic correlations in the single population scheme were significantly lower than the two population scheme when initial genetic correlation was negative. When terminal crossbreeding for the two population scheme is taken into account, superiority of the two population scheme was suggested. The terminal crossbreeding was effective under the situation of long term selection, existence of moderate inbreeding depression and use of less extreme economic weight.

적응형 변형 인식부를 이용한 침입 탐지 학습알고리즘 (Intrusion Detection Learning Algorithm using Adaptive Anomaly Detector)

  • 심귀보;양재원;김용수;이세열
    • 한국지능시스템학회논문지
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    • 제14권4호
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    • pp.451-456
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    • 2004
  • 징후 기반의 침입 탐지 시스템은 일정한 침입 탐지 규칙을 구성하여 라이브러리에 저장한 후 새로운 입력에 대해 규칙과 패턴 매칭을 하여 침입 여부를 판정한다. 그러나 징후(규칙)를 기반으로 하는 침입 탐지 시스템은 통상적으로 크게 2가지의 제약을 갖는다. 첫 번째는 침입에 대한 규칙을 구성하지 못할 경우 그에 따른 FN 오류(false negative error)가 발생할 수 있으며, 두 번째는 규칙의 다양성을 확보하기 위해서 많은 규칙을 구성하게 되었을 경우 그에 소요되는 자원의 규모가 커진다는 점이다. 이에 본 논문에서는 생체 면역 세포의 생성 과정인 부정 선택을 공학적으로 모델링하여 변형 인식부를 구성하고 이를 후보 개체군으로 하여 유전자 알고리즘을 이용해 진화시킴으로서 변이적인 침입에 대해 탐지 가능한 변형 인식부의 학습 알고리즘을 제안한다. 제안한 알고리즘은 컴퓨터 시뮬레이션을 통하여 그 유효성을 입증한다.