• Progress in Medical Physics
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• v.30 no.4
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• pp.150-154
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• 2019

The objective of this study is to monitor the radiation doses delivered to a cardiac implantable electronic device (CIED) by comparing the absorbed doses calculated by a commercial treatment planning system (TPS) to those measured by an in vivo dosimeter. Accurate monitoring of the radiation absorbed by a CIED during radiotherapy is necessary to prevent damage to the device. We conducted this study on three patients, who had the CIED inserted and were to be treated with radiotherapy. Treatment plans were generated using the Eclipse system, with a progressive resolution photon optimizer algorithm and the Acuros XB dose calculation algorithm. Measurements were performed on the patients using optically stimulated luminescence detectors placed on the skin, near the CIED. The results showed that the calculated doses from the TPS were up to 5 times lower than the measured doses. Therefore, it is recommended that in vivo dosimetry be conducted during radiotherapy for CIED patients to prevent damage to the CIED.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.2
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• pp.53.1-53.1
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• 2014

The M81 group is a nearby galaxy group hosted by M81, a twin galaxy of Milky Way. This galaxy group is considered as an ideal laboratory for near-field cosmology to understand mass assembly and evolution of galaxies in the group environment. We designed a project to investigate spectroscopic properties of globular cluster candidates in this group. We obtained spectra of globular cluster candidates using the MMT/Hectospec as a part of the K-GMT Science Program. Our main targets include globular cluster candidates of the M81 group member galaxies and those wandering in the intragroup region. We also observed supernova remnants and some background galaxies. Observing fields covered about 2 square degrees including three main galaxies of the M81 group. Using these spectra, we will identify globular clusters in the M81 group, and investigate their properties including age and metallicity. We will discuss the MMT/Hectospec data reduction processes, and future plan for this project.

• Genomics & Informatics
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• v.11 no.3
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• pp.102-113
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• 2013

Metagenomics has become one of the indispensable tools in microbial ecology for the last few decades, and a new revolution in metagenomic studies is now about to begin, with the help of recent advances of sequencing techniques. The massive data production and substantial cost reduction in next-generation sequencing have led to the rapid growth of metagenomic research both quantitatively and qualitatively. It is evident that metagenomics will be a standard tool for studying the diversity and function of microbes in the near future, as fingerprinting methods did previously. As the speed of data accumulation is accelerating, bioinformatic tools and associated databases for handling those datasets have become more urgent and necessary. To facilitate the bioinformatics analysis of metagenomic data, we review some recent tools and databases that are used widely in this field and give insights into the current challenges and future of metagenomics from a bioinformatics perspective.

• Journal of the Microelectronics and Packaging Society
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• v.17 no.2
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• pp.29-33
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• 2010

Among several critical topics in semiconductor fabrication technology, particles in addition to bonded surface contaminations are issues of great concerns. This study reports the development of a system which inspects wafer bond integrity by analyzing laser beam transmittance deviations and the variations of the intensity caused by the defect thickness. Since the speckling phenomenon exists inherently as long as the laser is used as an optical source and it degrades the inspection accuracy, speckle contrast is another obstacle to be conquered in this system. Consequently speckle contrast reduction methods were reviewed and among the all remedies have been established in the past 30 years the most adaptable solution for inline inspection system is applied. Simulation and subsequently design of experiments has been utilized to discover the best solution to improve irradiance distribution and detection accuracy. Comparison between simulation and experimental results has been done and it confirms an outstanding detection accuracy achievement. Bonded wafer inspection system has been developed and it is ready to be implemented in FAB in the near future.

• BMB Reports
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• v.49 no.8
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• pp.443-448
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• 2016

The arginylation branch of the N-end rule pathway is a ubiquitin-mediated proteolytic system in which post-translational conjugation of Arg by ATE1-encoded Arg-tRNA-protein transferase to N-terminal Asp, Glu, or oxidized Cys residues generates essential degradation signals. Here, we characterized the ATE1^−/− mice and identified the essential role of N-terminal arginylation in neural tube development. ATE1-null mice showed severe intracerebral hemorrhages and cystic space near the neural tubes. Expression of ATE1 was prominent in the developing brain and spinal cord, and this pattern overlapped with the migration path of neural stem cells. The ATE1^−/− brain showed defective G-protein signaling. Finally, we observed reduced mitosis in ATE1^−/− neuroepithelium and a significantly higher nitric oxide concentration in the ATE1^−/− brain. Our results strongly suggest that the crucial role of ATE1 in neural tube development is directly related to proper turn-over of the RGS4 protein, which participate in the oxygen-sensing mechanism in the cells.

• Nuclear Engineering and Technology
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• v.37 no.3
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• pp.265-272
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• 2005

Severe accidents in nuclear power plants can cause hydrogen-generating chemical reactions, which create the danger of hydrogen combustion and thus threaten containment integrity. For containment analyses, a three-dimensional mechanistic code, GOTHIC-3D has been applied near source compartments to predict whether or not highly reactive gas mixtures can form during an accident with the hydrogen mitigation system working. To assess the code applicability to hydrogen combustion analysis, this paper presents the numerical calculation results of GOTHIC-3D for various hydrogen combustion experiments, including FLAME, LSVCTF, and SNU-2D. In this study, a technical base for the modeling oflarge- and small-scale facilities was introduced through sensitivity studies on cell size and bum modeling parameters. Use of a turbulent bum option of the eddy dissipation concept enabled scale-free applications. Lowering the bum parameter values for the flame thickness and the bum temperature limit resulted in a larger flame velocity. When applied to hydrogen combustion analysis, this study revealed that the GOTHIC-3D code is generally able to predict the combustion phenomena with its default bum modeling parameters for large-scale facilities. However, the code needs further modifications of its bum modeling parameters to be applied to either small-scale facilities or extremely fast transients.

• The Bulletin of The Korean Astronomical Society
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• v.44 no.2
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• pp.40.3-40.3
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• 2019

Our recent observations of the Sun through strong spectral lines have revealed several important properties of the three-minute umbral oscillations inside sunspots -- the oscillations of intensity and Doppler velocity with periods of 2 to 3 minutes. The oscillations usually occur in the form of a time series of oscillation packets each of which lasts 10 to 20 minutes, not as continuous trains. Each oscillation packet is characterized by a singly peaked power spectrum of velocity oscillation. The oscillations propagate in the vertical direction from the photosphere to the corona. In the upper chromosphere, they develop into shocks that eventually collide with the transition region. When shocks propagate along a highly inclined direction, the merging of two successive shocks can take place. Once they enter the corona, they change to linear compressional waves. In the image plane, the three-minute oscillations propagate with high speeds in the transverse direction as well, usually propagating radially outwards from a point, and sometimes accompanying spiraling patterns of Doppler velocity. These observational properties can be theoretically explained by postulating the spatio-temporally localized source of fast MHD waves at a depth of about 2000 km below the surface, the excitation of slow MHD waves via mode conversion near the photosphere, and the resonance of the slow waves in the photospheric layer below the temperature minimum, and the nonlinear development of slow waves in the chromosphere.

• Proceedings of the Korean Society of Crop Science Conference
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• 2022.10a
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• pp.27-27
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• 2022

(-)-Epicatechin (EC), a primary form of flavan-3ol and a building block of proanthocyanidins, has health benefits as it is a potent antioxidant. So far, no quantitative trait loci (QTLs) associated with EC have yet been identified in soybean. In this study, QTLs for EC and hilum color were identified in recombinant inbred lines (RILs) derived from the varieties Jinpung and IT109098 using high-resolution single nucleotide polymorphism linkage mapping. This revealed two major QTLs for EC content, qEC06 and qEC08. qEC06 spanned the T Locus encoding flavonoid 3'-hydroxylase. qEC08, located near the I locus on Chr08, was also a major QTL for hilum color; however, allelic stacking of qEC08 and I revealed no relationship between I and EC content. RILs with IT 109098 alleles at both qEC06 and qEC08 had higher EC content than other lines. These results will enable the production of soybean varieties with high EC content via marker-assisted selection.

• Journal of Korean Neurosurgical Society
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• v.60 no.2
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• pp.262-268
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• 2017

Objective : Stents are widely used in coil embolization of intracranial aneurysms, but on occasion, a microcatheter must traverse a stented segment of artery (so-called trans-cell technique) to select an aneurysm, or double stenting may necessary. In such situations, microguidewire passage and microcatheter delivery through a tortuous stented parent artery may pose a technical challenge. Described herein is a microguidewire looping technique to facilitate endovascular navigation in these circumstances. Methods : To apply this technique, the microguidewire tip is looped before entering the stented parent artery and then advanced distally past the stented segment, with the loop intact. Rounding of the tip prevents interference from stent struts during passage. A microcatheter is subsequently passed into the stented artery for positioning near the neck of aneurysm, with microguidewire assistance. The aneurysm is then selected, steering the microcatheter tip (via inner microguidewire) into the dome. Results : This technique proved successful during coil embolization of nine saccular intracranial aneurysms (internal carotid artery [ICA], 6; middle cerebral artery, 2; basilar tip, 1), performing eight trans-cell deliveries and one additional stenting. Selective endovascular embolization was enabled in all patients, resulting in excellent clinical and radiologic outcomes, with no morbidity or mortality directly attributable to microguidewire looping. Conclusion : Microguidewire looping is a reasonable alternative if passage through a stented artery is not feasible by traditional means, especially at paraclinoid ICA sites.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.3 no.4
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• pp.183-192
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• 1998

The long-term observation of temperature in the coastal waters adjacent to the Wolsung Nuclear Power Plant has been carried out from November 10, 1996 to August 22, 1997, for approximately 280 days using a real-time temperature measurement buoy system. The sea-surface temperature was measured at every 10 minute using 10 buoys. The vertical structure of temperature was investigated near the outlet of the plant with two thermistor chains equipped with 10 sensors at 1 m interval The monthly averaged temperature was the lowest with spatial average of $12.8^{\circ}C$ in February and was the highest in August with spatial average of $19.6^{\circ}C$. The extremely low temperature was frequently observed between June and August, which seems to be the consequence of the intrusion of cold water near the southeastern coast of Korea. Distributions of the daily and hourly averaged temperature show that the highest temperature always occurred near the outlet of the plant and the warm-water patch moved along the north-south direction with the semidiurnal period. The semidiurnal fluctuation of temperature was also observed near the surface of the vertical profiles. The spectral analysis of temperature between February and April 1997 shows that the semidiurnal components prevailed near the outlet. It is likely that the semidiurnal components were due to the prevailing semidiurnal tide in this region. In August 1997, the diurnal components were dominant at the surface water of all stations except Station 12, which suggests that the warm water from the outlet of the plant has less effects in summer on the surrounding waters than the strong solar radiation.