• Genomics & Informatics
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• 제9권3호
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• pp.93-101
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• 2011

The Hairless (HR ) gene regulates the expression of several target genes as a transcriptional corepressor of nuclear receptors. The hair follicle (HF), a small independent organ of the skin, resides in the epidermis and undergoes regenerative cycling for normal hair formation. HF development requires many genes and signaling pathways to function properly in time and space, one of them being the HR gene. Various mutations of the HR gene have been reported to cause the hair loss pheno-type in rodents and humans. In recent studies, it has been suggested that the HR gene is a critical player in the regulation of the hair cycle and, thus, HF development. Furthermore, the HR gene is associated with the Wnt signaling pathway, which regulates proliferation and differentiation of cells and plays an essential role in hair and skin development. In this review, we summarize the mutations responsible for human hair disorders and discuss the roles of the HR gene in HF development.

• 한국공간정보시스템학회 논문지
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• 제9권3호
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• pp.81-89
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• 2007

본 논문은 품질기능전개(QFD)방법을 이용하여 기술포트폴리오를 분석하고 이를 바탕으로 차량항법 기술개발의 방향을 설정하고자 한다. 품질기능전개(QFD)방법은 고객의 요구와 관련된 기술적 역량을 연계 분석하는데 유용하게 사용된다. 우리는 본 논문에서 잠재고객을 대상으로 수요조사를 실시하고, 다양한 기초자료로 도출된 기술역량 데이터를 이용하여 기술포트폴리오 맵을 작성하고 분석하도록 한다. 그 결과에 의하면 영상HMI기술, 안전운전 지원기술, 단말정보관리기술 등이 상대적으로 기술적 역량과 기술 중요도가 모두 높은 유망한 투자대상 기술분야로 분석되었다.

• 소성∙가공
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• 제16권1호
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• pp.42-47
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• 2007

LCD-BLU is one of kernel parts of LCD and it consists of several optical sheets: LGP, light source and mold frame. The LGP of LCD-BLU is usually manufactured by etching process and forming numerous dots with $50\sim300{\mu}m$ diameter on the surface. But the surface of the etched dots of LGP is very rough due to the characteristics of the etching process during the mold fabrication, so that its light loss is high along with the dispersion of light into the surface. Accordingly, there is a limit in raising the luminance of LCD-BLU. In order to overcome the limit of current etched dot patterned LGP, optical pattern with continuous microlens was designed using optical simulation CAE. Also, a mold with continuous micro-lens was fabricated by UV-LiGA reflow process and applied to 7 inch size of navigator LCD-BLU in the present study.

• 수산해양기술연구
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• 제50권1호
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• pp.21-29
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• 2014

The dynamic information of radar and automatic identification system (AIS) for targets obtained from the traffic vessels operating in the north outer harbor and surrounding waters of Busan port, Korea. The target information was analyzed to investigate the potential collision risk resulting from the invalid true heading (HDT) information of AIS and the integration ambiguity in the graphic presentation of both tracked data sets for two systems. An integrated display system (IDS) for supporting the navigator of offshore fishing vessels was also developed to find possible maneuvering solutions for collision avoidance by comparing radar data with AIS data in real-time at sea. Consequently, the multiple functions of IDS can provide additional information that is potentially valuable for taking action to avoid the collision in offshore fishing vessels. However, the integration criteria of radar and AIS targets in the IDS must be carefully established to eliminate the fusion ambiguity in the graphic presentation of both AIS and radar symbols such as the one or two physical targets which are very close to each other.

• 한국주거학회논문집
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• 제28권1호
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• pp.55-62
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• 2017

As fast-speed of aging in modern society has led to increased concern for aging and health improvement of senior citizens, desire about having healthy living-environment has also increased. Living space for senior citizens has to play role of healing for their body feature as well as decrease in mental and psychological function. Color, as important factor that supplements degenerated sense and coping ability caused by aging, it has been revealed through modern medical science that color is effective for making nervous or calming down when it is delivered to one's nerve through sight. The purpose of this study is to suggest basic resource for color arrangement palette of living space and application method by color therapy to improve seniors' mental health by considering psychological and physical features caused by aging. First, consider psychological and physical feature of seniors and color therapy effect through previous research. Second, extract RGB value after selecting color that is helpful for their mental health by using palette from 'Korea Agency for Technology and Standards'. Third, extract other 3 colors that are similar with extracted color from 'NCS 1950 Color System'. Fourth, deduct palette of 3 color arrangement by using 'NCS Navigator' program. Lastly, extract arrangement palette for them by considering difference in visual features, and then suggest arrangement application for each palette through Computer Simulation.

• Journal of Korean Neurosurgical Society
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• 제56권1호
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• pp.16-20
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• 2014

Objective : Two-dimensional fluoroscopy-based computerized navigation for the placement of pedicle screws offers the advantage of using stored patient-specific imaging data in providing real-time guidance during screw placement. The study aimed to describe the accuracy and reliability of a fluoroscopy-based navigation system for pedicle screw insertion. Methods : A total of 477 pedicle screws were inserted in the lower back of 96 consecutive patients between October 2007 and June 2012 using fluoroscopy-based computer-assisted surgery. The accuracy of screw placement was evaluated using a sophisticated computed tomography protocol. Results : Of the 477 pedicle screws, 461 (96.7%) were judged to be inserted correctly. Frank screw misplacement [16 screws (3.3%)] was observed in 15 patients. Of these, 8 were classified as minimally misplaced (${\leq}2mm$); 3, as moderately misplaced (2.1-4 mm); and 5, as severely misplaced (>4 mm). No complications, including nerve root injury, cerebrospinal fluid leakage, or internal organ injury, were observed in any of the patients. Conclusion : The accuracy of pedicle screw placement using a fluoroscopy-based computer navigation system was observed to be superior to that obtained with conventional techniques.

• 한국정보처리학회논문지
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• 제7권2S호
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• pp.608-620
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• 2000

A web based E-mail system consists of serves which supply mail accounts and service, and clients which take part of interfacing with users. The web browsers such as Netscape Navigator and Internet Explorer are the popular clients. Users who cannot afford to get an E-mail id in general mail servers are, therefore, able to reach a e-mailing service in the web environment by using client programs in connection with a mail server. Although the quality of service has been upgraded a lot in recent days, it doesn't provide with satisfactory services anymore. In this paper, we intend to design a mail agent system based on the web environment. Through this system we could reach a convenient user interface based on Internet Explorer and could easily access administratory environment on the basis of NT Server 4.0. Using the service engine dominent in mail agent system, it could provide with convenient user interfacing tools like responding the absence of users, mail filtering and refusing messages, etc. And it would ultimately make possible a constant system security, by preventing system failure phenomena caused by extraordinary uses beyond its capability.

• 수산해양기술연구
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• 제39권1호
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• pp.77-83
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• 2003

Autonomous mobile robots based on the Web have been already used in public places such as museums. There are many kinds of problems to be solved because of the limitation of Web and the dynamically changing environment. We present a methodology for intelligent mobile robot that demonstrates a certain degree of autonomy in navigation applications. In this paper, we focus on a mobile robot navigator equipped with neuro-fuzzy controller which perceives the environment, make decisions, and take actions. The neuro-fuzzy controller equipped with collision avoidance behavior and target trace behavior enables the mobile robot to navigate in dynamic environment from the start location to goal location. Most telerobotics system workable on the Web have used standard Internet techniques such as HTTP, CGI and Scripting languages. However, for mobile robot navigations, these tools have significant limitations. In our study, C# and ASP.NET are used for both the client and the server side programs because of their interactivity and quick responsibility. Two kinds of simulations are performed to verify our proposed method. Our approach is verified through computer simulations of collision avoidance and target trace.

• 소성∙가공
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• 제22권6호
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• pp.317-322
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• 2013

A radio frequency(R/F) switch connector is widely used in wireless devices such as mobile phone and navigator to check defects of the circuit board of product. The R/F switch connector shell plays a role in protecting the switch connector. Previously, this part was machined using a turning, which is time-consuming and has poor material utilization. Furthermore, the workpiece material of brass containing lead that has excellent machinability has environmentally regulated during recent years. The purpose of the current study was to develop the connector shell by forming through progressive dies including embossing, burring and forging process in order to achieve higher productivity and dimensional accuracy without tool failure. To accomplish this objective, a strip layout was designed and finite element (FE) analysis was performed for each step in the process. Try-out for the connector shell was conducted using progressive die design based on FE-analysis results. Dimensional accuracy of developed part was investigated by scanning electron microscopy. The result of the investigation for the dimensions of the formed connector shell showed that the required dimensional accuracy was satisfied. Moreover, productivity using the progressive die increased four times compared to previous machining process.

• 수산해양기술연구
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• 제51권2호
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• pp.257-264
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• 2015

This study is intended to provide navigator with specific information necessary to assist the avoidance of collision and the operation of ships to evaluate the maneuverability of dead weight tonnage 8,000 tons Oil/Chemical tanker. The actual maneuvering characteristics of ship can be adequately judged from the results of typical ship trials. Author carried out sea trials based full scale for turning test, Z" maneuvering test, man overboard rescue maneuver test, inertia stopping test. Consequently, $2^{st}$ Overshoot yaw angle of the semi balanced rudder and flap rudder in ${\pm}20^{\circ}$ zig-zag test showed $22.2^{\circ}$ and $18.0^{\circ}$, respectively. The maneuverability of the vessel was good in the flap rudder. The man overboard rescue maneuver maneuverability test was most favorable in the flap rudder and the full load condition. The results from tests could be compared directly with the standards of maneuverability of IMO and consequently the maneuvering qualities of the ship is full satisfied with its.