• Journal of the Korean Academy of Esthetic Dentistry
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• v.14 no.1
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• pp.15-18
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• 2005

In order to recover the esthetic of the missing anterior area, we must consider color, shape of a tooth and the functions of a prosthesis that is harmonized with the surrounding factors. When the tooth of a natural tooth is exposed, we face to challenge to restore them. several factors cause resorption of bones, in flammation, and gum trouble, and a defective prosthesis damages the aesthetics of the gingiva. There are two ways how to solve these problems. One can be done by periodontal surgery and the other can be done by prosthesis. Most patients want aesthetic restoration that is harmonized with their teeth and gingiva. So if prosthesis is fabricated to expose the root exposed, it is far from the patient's expectation.

• Journal of Integrative Natural Science
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• v.11 no.1
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• pp.9-13
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• 2018

KiSS1-derived peptide receptor, a GPCR protein, binds with the hormone Kisspeptin plays a major role in the neuroendocrine regulation of reproduction. It is important in the onset of puberty and triggers the release of gonadotrophin-releasing hormone. It is a potential drug target for the disorders related to GnRH, hence, analysing the structural features of the receptor becomes important. The three dimensional of the receptor modelled in a previous study was utilised. In this study, we have analysed the protein - protein interaction of the receptor with Kisspeptin 10 and 15. The study revealed the important residues which are involved in the interaction. The result of this study could be helpful in understanding the mechanism of Kiss1 receptor activation and the pathophysiology of the disorders related to the receptor.

• Proceedings of the Optical Society of Korea Conference
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• 2003.07a
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• pp.82-83
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• 2003

PC의 대량 보급과 인터넷 케이블 망의 전지역적 구축을 통해 디지털 정보의 교류가 활발히 이루어지고 있다. 이에 따라 아날로그 이미지를 디지털화 하는 디지털 카메라나 스캐너와 같은 이미지 입력 장치와, 디지털 이미지를 눈으로 볼 수 있게 하는 모니터나 프린터와 같은 이미지 출력 장치로 구성되는 디지털 이미징 장치들의 사용이 일상화되고 있다. TV나 컴퓨터 모니터를 통한 인터넷 상품 구매는 이미 보편화되어 있고, 스캐너를 사용하여 사진을 스캔하여 수정이나 합성 등의 편집을 한 후 이미지를 웹에 올리거나 사진 프린터로 다시 뽑는 일에도 익숙해져 있다. (중략)

• Development and Reproduction
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• v.26 no.4
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• pp.183-190
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• 2022

Today's Eastern philosophers try to use the formal logic organized by Aristotle, saying that there was no logic in the East. This researcher found that Confucius and other Asians used Che-Yong logic. The Che-Yong logic is based on the Che-Yong law, which is a natural law. The Che-Yong law consists of the Che-Yong principle and the Hyeon-Mi principle. The Hyeon-Mi principle is that if there is an appearance on the outside, there is a corresponding cause in it. The Che-Yong principle is that the highest common cause of various appearances is Che, and the Che grows and changes on its own to become a Yong. Identifying Che and predicting Yong is Che-Yong logic. Here, I'd like to introduce Che-Yong logic and suggest a new research methodology to apply it.

• Journal of Integrative Natural Science
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• v.16 no.1
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• pp.33-38
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• 2023

The follicle stimulating hormone receptor (FSHR) is a glycoprotein hormone, that belongs to the GPCR superfamily. FSHR plays a major role in reproduction. The aberrant activation of FHS receptor leads to infertility and several reproductive disorders. The recently recognized roles of the FSHR in diverse extragonadal tissues is also closely related to Alzheimer's disease and cancers. Analysing the structural characteristics of the receptor is important in understanding the pathophysiology of diseases associated with the receptor. In this present study, homology modelling of FSHR-TM domain was developed using four different templates. Totally 20 models were developed using single template-based approach and selected three based on the validation of RC plot, RMSD, ProSA, QMEAN and ERRAT values. The developed models would be useful for further research on the structural characteristics and binding characteristics of the FSHR-TM domain.

• Physical Therapy Korea
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• v.19 no.3
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• pp.98-104
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• 2012

The aim of this study was to examine the effects of repeated passive movement (RPM) of different velocities on the improvement of knee joint position sense (JPS) in post-stroke patients with hemiplegia, thereby investigate the possibility of clinical application in the initial stage of rehabilitation for patients with post-stroke hemiplegia. Thirteen hemiplegic patients participated in this study. For the subjects' knee JPS tests, a passive angle reproduction test and an active angle reproduction test were performed prior to and after the intervention, which involved 30 repetitions of passive full-range-of-motion flexion and extension exercise of the knee joints at randomized degrees of $0^{\circ}/s$, $45^{\circ}/s$, and $90^{\circ}/s$. Paired t-test analysis was done in order to compare changes in the pre- and post-intervention knee JPS. One-way repeated analysis of variance was used in order to compare changes in JPS after intervention at three different movement velocities. The level of significance was set at .05. The result was that the subjects' post-intervention knee JPS significantly improved after the RPM exercise at a $45^{\circ}/s$ and a $90^{\circ}/s$ relative to the RPM exercise $0^{\circ}/s$ (p<.05). JPS changes with RPM intervention at the rapid velocity of $90^{\circ}/s$ were most increased, suggesting the most effective enhancement in knee JPS is with intervention at the velocity (p<.05). Therefore, RPM intervention at a half or higher velocity improved stroke patients' knee JPS. During the initial stage of rehabilitation for patients with post-stroke hemiplegia, the efficient application of the RPM exercise at a half or higher velocity will be possible.

• Development and Reproduction
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• v.15 no.2
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• pp.167-172
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• 2011

To monitor the reproductive patterns of endangered common chimpanzee including annual reproductive cycle, amenorrhea, breeding season, and pregnancy diagnosis, Time-Resolved Fluorescence Immuno Assay (TR-FIA) was used to trace MRH (estradiol, progesterone, testosterone) and human chorionic gonadotropin (HCG). In result of this research, age was not the important factor in determining the reproduction capability in common chimpanzee; it was rather greatly influenced by the combination of various factors such as individual's fertilizing ability, presence of obstetrical diseases, the pattern of mating behavior, and the mental communication under the introduction of a mating partner. This research will play an important role in operating conservation project for common chimpanzees and can be extended also for shedding new light on understanding human menopause and obstetrical diseases.

• Korean Journal of Animal Reproduction
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• v.27 no.4
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• pp.317-324
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• 2003

The present study were performed to analysis the hematocrit and the red blood cells content into the blood plasma of the transgenic pigs harboring recombinent human erythropoietin gene (rhEPO). Mouse whey acidic protein (mWAP) linked to rhEPO gene was microinjected into pronuclei of porcine one-cell zygotes. After delivered of offspring, PCR analyses identified one mWAP-rhEPO transgenic founder offspring(F$_{0}$). The first generation of transgenic pig (F$_{0}$) harboring mWAP-hEPO appeared to be a male, and the second generation (F$_1$) pigs were made by natural mating of F$_{0}$ with domestic swine, and male and female transgenic pigs (F$_1$) were identified by PCR. The blood samples from transgenic and normal pigs were collected for 50 days during lactation and were counted the red blood cell (RBC) numbers and Hematocrit (HCT) content into the blood. The transgenic pigs expressing rhEPO in their blood gave rise to higher RBC numbers and HCT contents than control animals. rhEPO was secreted both in the blood and milk of genetically engineered pigs harboring rhEPO gene. Therefore, this study provides a model regarding the production of transgenic pig carrying hEPO transgene for biomedical research.earch.

• The Korean Journal of Pesticide Science
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• v.19 no.4
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• pp.418-423
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• 2015

Effects of 9 acaricides to the predatory mite, Neoseiulus californicus were evaluated. Seven of the acaricides tested, cyenopyrafen. spirodiclofen, spiromesifen, acequinocyl, bifenazate, flufenoxuron and cyflumetofen exhibited low toxicity to adult females and nymphs of N. californicus and had little effect on the reproduction and eclosion of eggs deposited by treated predators. Moreover, hatch percentage of N. californicus eggs was unaffected by exposure to these seven acaricides. Etoxazole did not significantly affect the survival and reproduction of adult female predators but caused very low eclosion in eggs laid by treated females and high egg mortality. Pyraclofos was extremely toxic to adult female predators and caused 100% mortality. Adult female predators survived on a diet of spider mites treated with cyenopyrafen. spirodiclofen, spiromesifen, acequinocyl, bifenazate, flufenoxuron and cyflumetofen and their fecundity was not substantially affected. Based on the results, cyenopyrafen. spirodiclofen, spiromesifen, acequinocyl, bifenazate, flufenoxuron and cyflumetofen are appeared to be promising candidates for use in integrated mite management program where N. californicus is the major natural enemy.

• The Korean Journal of Mycology
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• v.12 no.3
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• pp.99-103
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• 1984

Hyphal growth by Fusarium moniliforme was best at -14 bars osmotic water potential. Hyphal growth was prevented at -94 bars. The production of microconidia was best at -14 bars osmotic potential and prevented at -84 bars regardless of Strain. In contrast, this fungus sporulated macroconidia best at -1.4 bars and progressively less with each increment drop in water potential below that of basal media. The rate of spore germination followed a similar pattern with all of the spores; uniformly maximal at about -1.4 bars and progressively slower as the water potential was lowered from -1.4 bars to -42 bars. Under the natural conditions, plants infected by F. moniliforme produce microconidia on the dead tissues instead of producing macroconidia. This phenomenon agrees well with the water potential experiment since the dead plant tissues have a lower water potential than the living plant.