• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.209.3-209.3
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• 2002

• Natural Product Sciences
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• 제24권3호
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• pp.159-163
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• 2018

Two new polyketides, chinoketides A and B (1 - 2) with a known compound xylarphthalide A (3), were isolated from the solid medium of the endophytes from the leaves of the relic plant Distylium chinense with the "black-box" co-culture method, and the structures of two new compounds were elucidated by NMR, MS and CD spectra. And the absolute configurations of chinoketides A (1) and B (2) were determined as 2R,3R,8S and 5R,6S by calculating their ECD spectra to compare with the experimental CD spectra. Finally, the antimicrobial activities were evaluated to Erwinia carotovora sub sp. Carotovora (Jones) Bersey et al, and the results showed that compounds 1 - 3 displayed the antimicrobial activities with MIC value at 20.5, 30.4 and $10.2{\mu}g/mL$.

• Natural Product Sciences
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• 제17권1호
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• pp.1-4
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• 2011

Chemical investigations of the stony coral Alveopora japonica Eguchi (Poritidae) resulted in the isolation of four known compounds (1 - 4). The structures of 1 - 4 were identified as a sterol, ergosta-5,24(28)-dien-$3{\beta}$-ol (1), a mixture of monoacyl glycrols (2), eicosanoic acid and tetracosanoic acid, and two nucleosides, thymine (3) and 2'-deoxythymidine (4), respectively, on the basis of spectroscopic and physicochemical analyses including 1D- and 2D- NMR techniques as well as by comparison of their data with the published values. Compounds 1 - 4 were isolated from this species for the first time. Moreover, these compounds (1 - 4) were found in the genus Alveopora and the family Poritidae for the first time.

• Natural Product Sciences
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• 제15권4호
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• pp.203-207
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• 2009

A homoisoflavanone, 7,4'-dihydroxyhomoisoflavanone (1) and a flavanone, (2S)-7,4'-dihydroxy-5-methoxyflavanone (2), were isolated from the rhizomes of Anemarrhena asphodeloides, together with 4,4'-dihydroxychalcon (3), 2'-O-methylphlorethin (4), 1,3-bis-di-p-hydroxyphenyl-4-penten-1-one (5), and 2,4'-dihydroxy-4-methoxybenzophenone (6) on the basis of spectroscopic and physicochemical analyses including 1Dand 2D- NMR techniques as well as by comparison of their data with the published values. Compounds 1 - 4 were isolated for the first time from this plant source. Among isolates, compound 2 exhibited moderate inhibitory effect on the differentiation of pre-adipocyte 3T3-L1 cells.

• Food Science and Biotechnology
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• 제17권4호
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• pp.846-849
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• 2008

This study employed high performance liquid chromatography (HPLC) coupled to an on-line $ABTS^+$ radical scavenging detection (RSD) system along with HPLC-electro spin impact/mass spectrometry (ESI/MS), to rapidly determine and identify antioxidant compounds occurring in blueberry extract. The extract was separated by HPLC, and then the radical scavenging activities of the separated compounds were evaluated by the on-line coupled $ABTS^+$-RSD system. The negative peaks of the $ABTS^+$-RSD system, which indicates the presence of antioxidant activity, were monitored by measuring the decrease in absorbance at 734 nm. The active components in the blueberry extract were identified by HPLC-ESI/MS using their MS spectra and retention times. According to the data acquired from the on-line HPLC-$ABTS^+$-based assay and HPLC-ESI/MS systems, the antioxidant compounds detected in the blueberry extract were identified as chlorogenic acid and 11 anthocyanins.

• 생약학회지
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• 제50권3호
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• pp.155-158
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• 2019

Cornus alba (CA) geographically distributes in Korea, Japan, Northeast China and Russia. The cornus species have been used traditionally as anti-inflammatory, hemostatic and diuretic in Korea. Previously, it was reported CA and its separated components have excellent antioxidant, anti-inflammatory and anti-prostate cancer efficacy. Present work, the validation and content determination was tried on the ellagitannin, cornusiin B which were isolated from the CA by using high-performance liquid chromatography (HPLC). As a result, the content of cornusiin B were 3.07% in ethanolic extract of CA.

• International Journal of Oral Biology
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• 제49권1호
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• pp.10-17
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• 2024

Glutamate-mediated oxidative stress causes neuronal cell death by increasing intracellular Ca²⁺ uptake, reactive oxidative species (ROS) generation, mitogen-activated protein kinase (MAPK) activation, and translocation of apoptosis-inducing factor (AIF) to the nucleus. In the current study, we demonstrated that corydaline exerts potent neuroprotective effects against glutamate-induced neurotoxicity. Treatment with 5 mmol/L glutamate increased cellular Ca²⁺ influx, ROS generation, MAPK activation, and AIF translocation. In contrast, corydaline treatment decreased cellular Ca²⁺ influx and ROS generation. Western blot analysis revealed that glutamate-mediated MAPK activation was attenuated by corydaline treatment. We further demonstrated that corydaline treatment inhibited the glutamate-mediated translocation of AIF to the nucleus. We propose that corydaline is a promising lead structure for the development of safe and effective neuroprotectants.

• Bulletin of the Korean Chemical Society
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• 제30권8호
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• pp.1884-1886
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• 2009

• 한국염색가공학회지
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• 제32권4호
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• pp.255-264
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• 2020

With the development of synthetic dyes, excellent dyeing properties and massive production became possible. On the other hand, natural dyeing technology has gradually disappeared. However, the international environmental and human safety requirements of the apparel and textile industry are increasing, and there is a growing interest in safer and more environmentally friendly products. Accordingly, the public's interest in natural dyeing is increasing. To meet these demands, it is first necessary to clarify the stages of production and distribution of natural dyes. It is necessary to evaluate whether the product is a natural dye product and study the suitability of the natural dye product through qualitative and quantitative assessment of the indicator components of the natural dye. Typical of three natural dyes did qualitative and quantitative analysis by HPLC-DAD and HPLC-MS. Products dyed using natural dye three products were analyzed, and the presence or absence of detection of each indicator components was confirmed to confirm whether the product was dyed using natural dyes.

• 한국의류학회지
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• 제34권7호
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• pp.1205-1219
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• 2010

This study analyzes the conditions and products of internet shopping malls that sell natural dyeing products. In this study, 98 natural dyeing internet shopping malls were selected. The results of this study are as follows. The locations of the internet shopping malls were Gyeonggi-do, Seoul, Jeollanam-do, Gyeongsangbuk-do, Gwang-ju (city), Daegu (city), Busan (city), Gyeongsangnam-do, and Jeju-do. The most frequent dyes of the natural dyeing products were loess, followed by charcoal, indigo, and persimmon. Indigo was most frequently used in Seoul, with loess and charcoal most frequent in Gyeonggi-do. Persimmon, indigo, loess, and charcoal were mainly used in Jeollanam-do, with persimmon and loess in the Gyeongsangbuk-do, and persimmon in Jeju-do. The highest ordered product categories were accessories, followed by adult clothing, interior decoration products, and bedding. The most frequent products were bedclothes, followed by scarves, female shirts, blouses, pillows, female jackets, and vests. Regarding the price of products, 150,000-200,000 won was the highest for the Saenghwal Hanbok, with 10,000-30,000 won for underwear, 30,000-60,000 won for accessories, and 100,000-150,000 won for bedding. Concerning product information, 58.2% of internet shopping malls offer the product size and almost half of them did not show the properties or directions for handling the product. Based on the research results, the problems of the conditions and products of natural dyeing internet shopping mall were derived. The results show that the natural dyes of internet shopping malls lacked regional symbolism, the products were not specialized, and product information was not fully offered to consumers. To solve these problems, the strategies for marketing the promotion of the natural dyeing internet shopping mall were, ‘Using natural dyes from local resources’, ‘Market oriented and specialized item design’, and ‘Offer right product information’.