• 한국물환경학회지
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• 제24권1호
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• pp.19-29
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• 2008

Hot air sparging is a groundwater remediation technique, in which organic contaminants volatilized into hot air from the saturated to vadose zone. In the laboratory diesel (10,000 mg TPH/kg) was spiked in contaminated saturated aquifer soil. The hot air ($34.9{\pm}2.7^{\circ}C$) was injected in intermittent (Q=1,500 mL/min, 10 minute injection and 10 minute idle) modes. We performed microcosm tests using the groundwater samples to assess TPH reductive remediation activity. For Terminal-Restriction Fragment Length Polymorphism (T-RFLP) analysis of eubacterial communities in sludge of wastewater treatment plants and soil of experiment site, the 16S rDNA was amplified by Polymerase Chain Reaction (PCR) from the sludge and the soil. The obtained 16S rDNA fragments were digested with Msp I and separated by electrophoresis gel. We found various sequence types for hot air sparging experiment with sludge soil samples that were closely related to Bacillus (149 bp, Firmicutes), Methlobacterium (149 bp, Euryarchaeotes), Pseudomonas (492 bp, ${\gamma}$-Proteobacteria), etc., in the clone library. In this study we find that TPH-water was reduced to 78.9% of the initial value in this experiment aquifer. The results of the present study suggests that T-RFLP method may be applied as a useful tool for the monitoring in the TPH contaminated soil fate of microorganisms in natural microbial community.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1995년도 춘계학술대회
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• pp.19-22
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• 1995

A biomechanical study was made to demonstrate the superior mechanical performance of the newly designed Miniplate staple to the conventional Coventry staple in high tibial osteotomy(HTO). Using twenty fresh porcine tibiae, the fixational strengh of the two different types of staple in HTO was compared. To minimize the error due to the specimen-to-specimen individuality, the bone mineral density of the tibiae was measured with a bone densitometry (Dual photon absorptionometer, Luner, USA) and those with $0.8\;{\sim}\;1.2\;gm/cm^2$ at the proximal tibia was used in the biomechanical test. Testing was performed on a material testing system (Autogram ET-5, Shimatzu, Japan) with aid of a commercial data processor (IBM 80386/ ASYST). Using two differant loading modes, 'pull-out' and 'push-out', the maximum resistant force required to release the staple from the substrate bone was recorded. In the pull-out test, ten non-osteotomized specimens were used and the staple was pullout by subjecting an axial tension on the head of the staple inserted. While in the pull-out test where ten tibiae osteotomized in the usual way of HTO were used, the staple was not directly loaded. In this testing, as a mimic condition of the natural knee, the distal part of the specimen tibia was pushed horizontally in order for the staple to be pulled out while the proximal tibia was fixed. The pull-out strength of Coventry staple and miniplate staple were found to be $27.88\;{\pm}\;5.12\;kgf$ and $182.47\;{\pm}\;32.75\;kgf$, respectively. The push-out strength of Coventry staple and miniplate staple were $18.40\;{\pm}\;4.47\;kgf$ and $119.95\;{\pm}\;19.06\;kgf$, respectively. The result revealed that miniplate staple had the pull-out/ push-out strength at least fivetimes higher than Coventry staple. Based on the measured data, it was believed that the newly designed miniplate staple could provide much better postoperative fixation in HTO. The postoerative application of long leg casting may not be needed after HTO surgery.

• 한국지진공학회논문집
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• 제7권2호
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• pp.1-7
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• 2003

모우드 중첩법은 구조 동역학 문제의 선형 거동해를 위해서 가장 일반적으로 사용되고 있다. 이러한 모우드 중첩법의 큰 장점은 보통 저차 모우드의 작은 수 만으로 구조물의 거동해석이 충분하다는 것이다. 그러나 많은 수의 자유도를 갖는 거대 구조물에서는 수렴속도가 느리고, 정확한 모우드 중첩법이 되기 위해서는 많은 수의 모우드 수가 필요하게 된다. 모우드 중첩법의 부정확성은 사용되는 모우드 수의 절삭에 의해서 발생된다. 이러한 단점들은 모우드 가속도법에 의해서 극복될 수 있다. 조화하중을 받는 단순보에 대하여 예제해석을 수행하였으며, 두 방법에 의해서 절점 변위들의 수렴성을 비교하였다. 비교적 낮은 주파수를 갖는 하중에 대하여 모우드 가속도법은 저차 모우드 1개만으로도 좋은 결과를 얻을 수 있었으며, 이 방법은 수치해석에 있어서 더 경제적이며 또한 정확한 해가 된다.

• 대한조선학회지
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• 제27권4호
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• pp.3-14
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• 1990

해상에 계류된 부유체에 좁은 폭의 스펙트럼을 갖는 파가 입사하게 되면 부유체는 두 가지의 대조적인 주기를 갖고 운동을 한다. 이 운동중 장주기 성분의 주기는 계류된 부유체의 수평방향 고유주기와 같은 정도의 크기여서 유발되는 대진폭 수평 변위는 계류삭에 심각한 응력을 발생시키므로 이에 대한 해석이 필요하다. 본 연구에서는 다척도전개기법(Multiple-Scale Expansion Method)을 시간과 길이에 적용하여 부유체의 운동은 선형 1차 조화 문제와 선형 장주기 문제의 2가지 선형 문제로 표현될 수 있음을 보였다. 따라서 임의 형상을 지닌 3차원 부유체의 대진폭 표류 운동은 2차 포텐셜문제를 풀지않고 해석될 수 있음을 입증하였다. 아울러 장주기 표류운동에 수반되어 장파가 발생함을 보였으며 장주기 운동과 관련되는 감쇠력에 대해서도 고찰하였다.

• 한국전산구조공학회논문집
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• 제30권4호
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• pp.319-327
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• 2017

본 연구에서는 콘크리트 석션식 지지구조물을 사용한 해상풍력발전시스템의 지진응답 해석을 수행하여 그 거동 특성을 파악한다. 전체 시스템을 RNA, 타워, 지지구조물로 구성된 구조계와 이에 접하고 있는 유체 및 지반의 부분구조로 분리하여 운동방정식을 유도한다. 구조계에 작용하는 유체의 동수압과 지반의 상호작용력을 산정하고, 이를 구조계의 운동방정식과 결합하여 전체 시스템의 지배방정식을 도출한 후, 이 방정식의 해를 구하여 해상풍력발전시스템의 지진응답을 계산한다. 해석 결과로부터 지반-구조물 상호작용은 콘크리트 석션식 지지구조물에 의해 지지된 해상풍력발전시스템의 지진응답을 크게 증가시킬 수 있음을 확인할 수 있다. 특히, 지반의 유연성으로 인해 시스템의 고차 고유모드 응답이 증가할 수 있으므로, 해상풍력발전시스템의 동적거동 산정 시에는 반드시 지반-구조물 상호작용의 효과를 고려하여야 할 것이다.

• Smart Structures and Systems
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• 제17권2호
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• pp.209-230
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• 2016

The Canton Tower is a high-rise slender structure with a height of 610 m. A structural health monitoring system has been instrumented on the structure, by which data is continuously monitored. This paper presents an investigation on the identified modal properties of the Canton Tower using ambient vibration data collected during a whole day (24 hours). A recently developed Fast Bayesian FFT method is utilized for operational modal analysis on the basis of the measured acceleration data. The approach views modal identification as an inference problem where probability is used as a measure for the relative plausibility of outcomes given a model of the structure and measured data. Focusing on the first several modes, the modal properties of this supertall slender structure are identified on non-overlapping time windows during the whole day under normal wind speed. With the identified modal parameters and the associated posterior uncertainty, the distribution of the modal parameters in the future is predicted and assessed. By defining the modal root-mean-square value in terms of the power spectral density of modal force identified, the identified natural frequencies and damping ratios versus the vibration amplitude are investigated with the associated posterior uncertainty considered. Meanwhile, the correlations between modal parameters and temperature, modal parameters and wind speed are studied. For comparison purpose, the frequency domain decomposition (FDD) method is also utilized to identify the modal parameters. The identified results obtained by the Bayesian method, the FDD method and a finite element model are compared and discussed.

• Smart Structures and Systems
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• 제25권1호
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• pp.81-96
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• 2020

Wind measurements were made on the Canton Tower at a height of 461 m above ground during the Typhoon Vincente, the wind-induced accelerations and displacements of the tower were recorded as well. Comparisons of measured wind parameters at upper level of atmospheric boundary layer with those adopted in wind tunnel testing were presented. The measured turbulence intensity can be smaller than the design value, indicating that the wind tunnel testing may underestimate the crosswind structural responses for certain lock-in velocity range of vortex shedding. Analyses of peak factors and power spectral density for acceleration response shows that the crosswind responses are a combination of gust-induced buffeting and vortex-induced vibrations in the certain range of wind directions. The identified modal frequencies and mode shapes from acceleration data are found to be in good agreement with existing experimental results and the prediction from the finite element model. The damping ratios increase with amplitude of vibration or equivalently wind velocity which may be attributed to aerodynamic damping. In addition, the natural frequencies determined from the measured displacement are very close to those determined from the acceleration data for the first two modes. Finally, the relation between displacement responses and wind speed/direction was investigated.

• Archives of Pharmacal Research
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• 제27권2호
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• pp.199-205
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• 2004

Cytochrome P450 (P450) 1 enzymes such as P450 1A1, 1A2, and 181 are known to be involved in the oxidative metabolism of various procarcinogens and are regarded as important target enzymes for cancer chemoprevention. Previously, several hydroxystilbene compounds were reported to inhibit P450 1 enzymes and were rated as candidate chemopreventive agents. In this study, we investigated the inhibitory effect of 2-[2-(3,5-dimethoxyphenyl)vinyl]-thiophene (DMPVT), produced from the chemical modification of oxyresveratrol, on the activities of P450 1 enzymes. The inhibitory potential by DMPVT on the P450 1 enzyme activity was evaluated with the Escherichia coli membranes of the recombinant human cytochrome P450 1A1, 1A2, or 1B1 coexpressed with human NADPH-P450 reductase. DMPVT significantly inhibited ethoxyresorufin O-deethylation (EROD) activities with $IC_{50}$ values of 61, 11, and 2 nM for 1A1, 1A2, and 1B1, respectively. The EROO activity in OMBA-treated rat lung microsomes was also significantly inhibited by OMPVT in a dose-dependent manner. The modes of inhibition by DMPVT were non-competitive for all three P450 enzymes. The inhibition of P450 1B1-mediated EROD activity by OMPVT did not show the irreversible mechanism-based effect. The loss of EROD activity in P450 1B1 with OMPVT incubation was not blocked by treatment with the trapping agents such as glutathione, N-acetylcysteine, or dithiothreitol. Taken together, the results suggested DMPVT to be a strong noncompetitive inhibitor of human P450 1 enzymes that should be considered as a good candidate for a cancer chemopreventive agent in humans.

• Tuberculosis and Respiratory Diseases
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• 제43권2호
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• pp.267-273
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• 1996

저자들은 최근 다발성 폐동맥 폐쇄를 동반한 Takayasu 동맥염 1예을 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2010년도 학술발표회
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• pp.268-272
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• 2010

The research presented here represents a collaborative effort with the SFWMD on developing scenarios for future climate for the SFWMD area. The project focuses on developing methodology for simulating precipitation representing both natural quasi-oscillatory modes of variability in these climate variables and also the secular trends projected by the IPCC scenarios that are publicly available. This study specifically provides the results for precipitation modeling. The starting point for the modeling was the work of Tebaldi et al that is considered one of the benchmarks for bias correction and model combination in this context. This model was extended in the framework of a Hierarchical Bayesian Model (HBM) to formally and simultaneously consider biases between the models and observations over the historical period and trends in the observations and models out to the end of the 21st century in line with the different ensemble model simulations from the IPCC scenarios. The low frequency variability is modeled using the previously developed Wavelet Autoregressive Model (WARM), with a correction to preserve the variance associated with the full series from the HBM projections. The assumption here is that there is no useful information in the IPCC models as to the change in the low frequency variability of the regional, seasonal precipitation. This assumption is based on a preliminary analysis of these models historical and future output. Thus, preserving the low frequency structure from the historical series into the future emerges as a pragmatic goal. We find that there are significant biases between the observations and the base case scenarios for precipitation. The biases vary across models, and are shrunk using posterior maximum likelihood to allow some models to depart from the central tendency while allowing others to cluster and reduce biases by averaging. The projected changes in the future precipitation are small compared to the bias between model base run and observations and also relative to the inter-annual and decadal variability in the precipitation.