• Nutrition Research and Practice
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• 제10권5호
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• pp.524-529
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• 2016

BACKGROUND/OBJECTIVES: Use of smaller plates to control food intake is a commonly recommended strategy for restricting energy intake, despite conflicting results. Therefore, the aim of this study was to examine whether or not three different sizes of plates influence energy intake during a multi-itemed buffet meal in normal weight women. SUBJECTS/METHODS: This was a cross-over study conducted on 37 female participants aged 19-25 years with normal BMI levels. Participants were recruited from Hacettepe University and the surrounding community. On experimental days, participants ate a standard breakfast and were then randomly assigned to eat lunch using a small (19 cm), medium (23 cm), or large (28 cm) diameter plate. Visual analogue scale (VAS) scores on sensory and satiety outcomes were measured for all meals. Energy and macronutrient intakes during lunch were recorded. RESULTS: There was no evidence that use of a smaller plate size reduced energy or specific macronutrient intake during the free choice lunch meal. Multiple visits to the serving table were not associated with energy or macronutrient intake. Plate size did not affect VAS scores during the test days. CONCLUSIONS: Plate size did not influence energy intake, meal composition, or palatability in normal weight women during a multi-itemed open buffet lunch. Studies in natural settings at the population level are needed to clarify current outcomes.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제39권1호
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• pp.14-20
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• 2013

Objectives: This study sought to evaluate the effect of simultaneous application of arthrocentesis and occlusal splint. Materials and Methods: A retrospective study of 43 patients (3 males, 40 females) whose symptoms had improved was conducted at the Department of Oral and Maxillofacial Surgery, Dong-A University Hospital between 2008 and 2010. Subjects were divided into three groups: Group A (17 patients with arthrocentesis and occlusal splints simultaneously applied), Group B (13 patients whose symptoms did not improve with occlusal splints, undergoing arthrocentesis after occlusal splint use for 8 weeks), and Group C (13 patients that only used occlusal splints). We compared these groups in maximum comfortable opening (MCO) and the visual analogue scale of pain and noise. Follow-up was performed at 1 week, 1 month, 3 months, and 6 months. Results: The improvement of symptoms was noted in all three groups, but Group A had a quicker improvement than the other groups, in terms of pain reduction and MCO increases. Conclusion: The simultaneous application of arthrocentesis and occlusal splints can reduce patient discomfort more quickly.

• 한국전문물리치료학회지
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• 제22권1호
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• pp.37-48
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• 2015

This study aimed to investigate the effect of the abdominal drawing-in maneuver (ADIM) and abdominal expansion maneuver (AEM) on trunk stabilization, as well as trunk muscle activities and differences in quadruple visual analogue scale, Korean Oswestry Disability Index, and Fear Avoidance Beliefs Questionnaire scores, in patients with chronic low back pain and lumbar spine instability. To increase intra-abdominal pressure during the trunk stabilization exercise, the technique of pushing the abdomen out using diaphragmatic abdominal breathing suggested by Pavel Koral was used, which we termed the AEM. Fifty patients who tested positive on more than three of the five lumbar spine instability tests were separated from 138 patients with chronic low back pain of these patients, 16 were placed in the control group (trunk stabilization exercise), 17 were placed in the ADIM group (trunk stabilization exercise with ADIM), and 17 were placed in the AEM group (trunk stabilization exercise with AEM). Each group participated in the study for 30 minutes three times weekly for 4 weeks. Surface electromyography was used to measure the trunk muscle activities during the kneeling forward and supine bridging positions, and one-way repeated analysis of variance was used to determine the statistical significance of the trunk muscle activities in the rectus abdominis, internal oblique (IO), erector spinae, and multifidus (MF) muscles. The ADIM and AEM groups showed relatively larger improvements in psychosocial and functional disability level than control group. There were significant changes among the three groups, those from the measured values of the AEM group was significantly higher than the other two groups in changes in IO and MF trunk muscle activities (p<.05). This finding demonstrates that trunk stabilization exercises with AEM is more effective than ADIM for increasing trunk deep muscle activity of chronic low back pain patients with lumbar spine instability.

• Archives of Pharmacal Research
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• 제28권5호
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• pp.518-528
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• 2005

In the present study, the antioxidative and inhibitory activity of Zingiber officinale Rosc. Rhizomes-derived materials (on mushroom tyrosinase) were evaluated. The bioactive co mponents of Z. officinale rhizomes were characterized by spectroscopic analysis as zingerone and dehydrozingerone, which exhibited potent antioxidant and tyrosinase inhibition activities. A series of substituted dehydrozingerones [(E)-4-phenyl-3-buten-2-ones] were prepared in admirable yields by the reaction of appropriate benzaldehydes with acetone and the products were evaluated in terms of variation in the dehydrozingerone structure. The synthetic analogues were examined for their antioxidant and antityrosinase activities to probe the most potent analogue. Compound 26 inhibited Fe$^{2+}$-induced lipid peroxidation in rat brain homogenate with an IC$_{50}$ = 6.3${\pm}$0.4 ${\mu}$M. In the 1,1-diphenyl- 2-picrylhydrazyl (DPPH) radical quencher assay, compounds 2, 7, 17, 26, 28, and 29 showed radical scavenging activity equal to or higher than those of the standard antioxidants, like ${\alpha}$-tocopherol and ascorbic acid. Compound 27 displayed superior inhibition of tyrosinase activity relative to other examined analogues. Compounds 2, 17, and 26 exhibited non-competitive inhibition against oxidation of 3,4- dihydroxyphenylalanine (L-DOPA). From the present study, it was observed that both number and position of hydroxyl groups on aromatic ring and a double bond between C-3 and C-4 played a critical role in exerting the antioxidant and antityrosinase activity.

• 방사성폐기물학회지
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• 제7권1호
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• pp.63-72
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• 2009

방사성폐기물 처분에서 미생물에 대한 연구는 최근에 중요한 연구 결과들이 지속적으로 발표됨에 따라 그 중요성에 대한 인식이 차츰 확대되고 있는 추세이다. 본 연구에서는 방사성폐기물 처분에서 미생물의 역할과 영향들에 대한 연구결과 및 연구동향을 조사 분석하였다. 방사성폐기물 처분시스템에서 고려되고 있는 다중방벽들인 인공방벽과 자연방벽에서의 미생물들의 역할 및 연구결과를 정리하여 제시하였다. 인공방벽에서는 처분용기의 부식에 대한 영향과 압축된 완충재에서의 미생물의 생존가능성 및 역할에 대해 논의하였다. 천연방벽에서는 지하수 및 암반에 존재하는 미생물들의 역할을 자연유사연구 결과와 함께 정리하여 제시하였다. 또한 지하매질을 통한 핵종이동 및 지연특성에서 미생물의 역할과 다양한 작용과정들 및 영향을 최근 연구동향과 함께 분석하고 정리하여 제시하였다. 따라서 향후 심부 지하 환경에서 처분시스템의 거동 및 지중매질을 통한 방사성 핵종의 이동 등에 미치는 미생물의 영향에 대한 심도 있는 연구가 본격적으로 수행된다면 미생물의 중요성 및 역할에 대한 엄격한 평가를 할 수 있을 것으로 사료된다.

• 한국산학기술학회논문지
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• 제16권1호
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• pp.490-497
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• 2015

본 연구는 신체적 기능장애를 지닌 국가유공자의 삶의 질 수준을 확인하고 삶의 질에 영향을 미치는 관련 요인들을 알아보기 위하여 실시하였다. 연구대상자는 서울, 부산, 대구, 광주와 대전에 위치한 보훈병원에서 신체적 기능장애로 치료를 받고 있는 국가유공자 412명을 대상으로 하였다. 대상자의 삶의 질은 SF-36을 이용하여 평가하였고, 일상생활동작은 수정된 바델지수로, 통증수준은 4항목 시각적 상사척도로, 우울증 척도는 노인우울척도를 이용하여 평가하였다. 연구 결과, 삶의 질은 연령이 높을수록, 주관적 건강상태가 나쁠수록, 경제수준이 낮을수록, 와병기간이 길수록, 통증수준, 우울증 점수가 높을수록 유의하게 낮아지는 것으로 나타났다. 회귀분석 결과 삶의 질에 가장 크게 영향을 미치는 변수는 우울증(B=-.969)이었으며, 주관적 건강상태(B=-5.098), 일상생활동작 수행(B=.140), 통증수준(B=-.163) 순으로 나타났다. 따라서 본 연구의 결과는 신체적 기능장애를 지닌 국가유공자의 삶의 질 향상을 위해 심리적 접근 뿐 아니라 일상생활동작 수행정도 등 신체적 증상의 완화, 통증감소를 개선시킬 수 있는 의학적 중재 및 프로그램 개발의 기초자료로 활용될 수 있을 것이다.

• 대한물리의학회지
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• 제3권3호
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• pp.203-213
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• 2008

Purpose : The purpose of the study was to investigate the effects of sustained natural appophyseal glides (SNAGS) on pain and lumbar stability in patients with chronic low back pain. Methods : The subjects were assigned randomly devided SNAGS group(n=18) and control group(n=18). The SNAGS group received Infrared(IR) used thermal therapy for 20minutes, Interference current therapy(ICT) used electrical therapy for 10minutes and SNAGS for 10minutes to 15minutes. The control group received IR used thermal therapy for 20minutes, ICT used electrical therapy for 10minutes and active stretching exercise for 10minutes to 15minutes. The visual analogue scale(VAS) and lumbar stability were measured at pre-treatment and post-treatment. Results : The results of this study were summarized as follows : 1. The VAS score of SNAGS group and control group was significantly within-subjects pre-test and post-test (p<.05), there was significantly difference between-subjects on each groups(p<.05). 2. The SNAGS group was significantly increased in variation of lumbar stability on $0^{\circ}$, $180^{\circ}$, $90^{\circ}$, $-90^{\circ}$, $45^{\circ}$, $-45^{\circ}$, $135^{\circ}$ and $-135^{\circ}$ within-subjects pre-test and post-test(p<.05), but The control group wasn't significantly increased in variation of lumbar stability on $0^{\circ}$, $180^{\circ}$, $90^{\circ}$, $-90^{\circ}$, $45^{\circ}$, $-45^{\circ}$, $135^{\circ}$ and $-135^{\circ}$ within-subjects pre-test and post-test(p>.05). There was significantly difference between-subjects on each groups(p<.05). Conclusion : In conclusion, SNAGS found that effective to decrease of pain and increase of lumbar stability. Therefore, the results of this study suggests that SNAGS is beneficial treatment for chronic low back pain.

• 대한한방부인과학회지
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• 제26권4호
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• pp.123-139
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• 2013

Purpose: Cold hypersensitivity is regarded to be associated with blood circulation. This study is aims to evaluate the effects and safety of oxygen chamber therapy on cold hypersensitivity by comparing the temperature and Visual Analogue Scale. Methods: 42 outpatients who visited ${\bigcirc}{\bigcirc}$ University Oriental Hospital from July 11th, 2013 to August 28th, 2013 were analyzed. Patients were subjected to thermometer, and those with thermal difference greater than $0.3^{\circ}C$ between upper arm and palm and also with more than VAS 4 of cold hypersensitivity were diagnosed with cold hypersensitivity. 42 outpatients diagnosed with cold hypersensitivity are divided into two groups, one is the experimental group consisted of 21 patients and other was control group consisted of 21 patients. The experimental group had oxygen chamber therapy 10 times for 4 weeks. Thereafter the effects of oxygen chamber therapy on cold hypersensitivity was analyzed with t-text using SPSS for Windows version 21. Results: After the oxygen chamber therapy, experimental group had considerable improvement on cold hypersensitivity, in consequence of decreasing rate of thermal difference and VAS of cold hypersensitivity. Ear deafness and hand numbness were reported as an adverse effects in experimental group, but there was no serious adverse effects. Conclusions: This clinical trial showed oxygen chamber therapy could be effective and safe to reduce cold hypersensitivity.

• 한국전문물리치료학회지
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• 제19권3호
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• pp.51-60
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• 2012

This study aimed to determine the usefulness of classifying patients with neck pain on the basis of the results of passive scapular elevation test. We classified 21 patients with neck pain into positive (n=12) and negative (n=9) groups on the basis of passive scapular elevation test; the 2 groups then equally performed scapular stabilization exercise program for 30 min, 3 times a week, for 4 weeks. Visual analogue scale (VAS), neck disability index (NDI), and range of motion (ROM) were recorded both before and after the intervention for both groups. Paired t-test was used to determine that there were significant changes between before and after the intervention, and independent t-test was used for analyzing changes between two groups of dependent variables. After 4 weeks of training, we observed significant decrease in pain and disability (p<.05) and a significant increase in rotation, flexion, extension, and side-bending ROM (p<.05) in both groups. Further, between pre- and post-intervention evaluations, we observed a significant decrease in pain and disability and a significant increase in rotation and flexion ROM in the positive group than in the negative group (p<.05). These results indicate that passive scapular elevation test may be used to identify mechanical disorders of the cervicoscapular muscle in patients with neck pain. Therefore, we recommend the use of passive scapular elevation test to determine appropriate treatment intervention when treating patients with neck pain.

• 생명과학회지
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• 제22권6호
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• pp.815-822
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• 2012

Resveratrol 유도체의 일종으로 stilbene계열 물질인 piceatannol은 암세포의 증식을 억제하고 apoptosis를 유발하는 것으로 알려져 있다. 본 연구에서는 A549 인체 폐암세포를 대상으로 piceatannol에 의한 암세포 증식억제와 연관된 부가적인 기전연구를 실시하였다. 본 연구의 결과에서 piceatannol이 A549 세포에서 extrinsic 및 intrinsic pathway의 동시 활성을 통하여 apoptosis를 유발하였음을 Fas/FasL의 발현 증가와 caspase-8 및 -9의 활성증가로 확인하였다. 또한 piceatannol은 caspase-3의 활성을 증가시켰으며, caspase-3의 다양한 표적 단백질들의 발현 감소가 동반되었다. 아울러 piceatannol에 의한 apoptosis 유발 과정은 iNOS의 발현 감소에 의한 NO의 생성 억제와도 연관성이 있었다.