• Journal of The Korean Association For Science Education
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• v.13 no.2
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• pp.210-218
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• 1993

Scientific literacy for all became a new goal and introducing STS issues into science curriculum shows new trends in science education. The educational importance of natural environment of a region is increasing because it can serve as a vehicle to meet the new goal and trends of science education. The opportunity to learn about Korean natural environment in schools was investigated. The characteristics and unique patterns of Korean natural environment are not well reflected in the intended curriculum. School teachers mostly believe that education of Korean natural environment will greatly contribute to the students' learning of the subject matter they teach and environmental problems. However, they have limited opportunity to teach Korean natural environment. Various elective courses dealing with our natural environment should be provided in schools, especially for non-science majors. Out-of-school activities and facilities for Korean natural environment should be made available.

• Hwankyungkyoyuk
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• v.22 no.2
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• pp.92-106
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• 2009

We assumed that natural history museums have rooms for functioning as institutions for the environmental education, especially in aspects of multi-disciplinary, informal education. So we set goals of this research as finding 1) how much environmental education contents are reflected in exhibits of natural history museums, and 2) what those characteristics in aspects of dimension, range, and topic are. First, we developed a framework for analyzing of environmental education contents. Second, we applied the framework to seven major natural history museums. As the result, environmental education contents are reflected by 69.1% totally. Especially, the 'knowledge' dimension covered mostly, and among them the range of 'elements of Ecosystem' occupied more than other ranges. With inferring our results, we suggested that characteristics of natural history museums in environmental education are followed; spatial-temporal expansion of bio-diversity concept, visualizing impacts of human activity against nature.

• Journal of The Korean Association For Science Education
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• v.24 no.1
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• pp.63-75
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• 2004

The purpose of this study is to explore characteristics of on-line teaching materials on websites of natural history museums, particularly with regard to educational perspectives and the nature of science. The target resources were selected from the websites of the Natural History Museum in London, the Australian Museum in Sydney, the Field Museum of Natural History in Chicago, and the Smithsonian Museum in Washington D.C.. A total of twelve on-line resources from these museums used in this study were selected as representative informal science teaching materials. For the investigation, this study developed a checklist with a total of nine items that were grounded on mostly reviewing previous literature and articles focusing on educational perspectives of natural history museums and science centers. Exciting and positive results were found in all four museums. The analyses, however, indicated weaknesses as well as strengths in on-line resources regarding their usages as informal science teaching venues.

• Hwankyungkyoyuk
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• v.21 no.1
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• pp.45-56
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• 2008

This study is to consider the fundamental perceptions of pre-service elementary school teachers to natural environments. The recognition items of questionnaire for those environments include ones of water, atmospheric, soil, biologic and oceanic environments constituting of the earth system. From the results of the study, they affirmatively recognized biologic environment, but they showed highly negative recognitions to others. In other side, it is considered that their recognitions to natural environments were probably transferred by the things which involve press media, curricula and real lives. On the basis of the study results, systematic teaching-learning for natural environments is essential because the encouragement of eco-friendly attitude, one of main goal for environmental education, is budded from basic understandings to natural environments. Affirmatively environmental worldviews for elementary school students are important for reasons why teacher's quality and practice will is fundamental, and then teacher could change the views of the students for environmental education. So, preparing balanced attitudes, right concepts and connection to applicable knowledges for natural environments, pre-service elementary school teachers in environmental education must be pointed to organized education between human and natural environment.

• Journal of Ginseng Research
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• v.46 no.6
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• pp.738-749
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• 2022

Background: Ginseng possesses antitumor effects, and ginsenosides are considered to be one of its main active chemical components. Ginsenosides can further be hydrolyzed to generate secondary saponins, and 20(R)-panaxotriol is an important sapogenin of ginsenosides. We aimed to synthesize a new ginsengenin derivative from 20(R)-panaxotriol and investigate its antitumor activity in vivo and in vitro. Methods: Here, 20(R)-panaxotriol was selected as a precursor and was modified into its derivatives. The new products were characterized by ¹H-NMR, ¹³C-NMR and HR-MS and evaluated by molecular docking, MTT, luciferase reporter assay, western blotting, immunofluorescent staining, colony formation assay, EdU labeling and immunofluorescence, apoptosis assay, cells migration assay, transwell assay and in vivo antitumor activity assay. Results: The derivative with the best antitumor activity was identified as 6,12-dihydroxy-4,4,8,10,14-pentamethyl-17-(2,6,6-trimethyltetrahydro-2H-pyran-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl(tert-butoxycarbonyl)glycinate (A11). The focus of this research was on the antitumor activity of the derivatives. The efficacy of the derivative A11 (IC₅₀ < 0.3 µM) was more than 100 times higher than that of 20(R)- panaxotriol (IC₅₀ > 30 µM). In addition, A11 inhibited the protein expression and nuclear accumulation of the hypoxia-inducible factor HIF-1α in HeLa cells under hypoxic conditions in a dose-dependent manner. Moreover, A11 dose-dependently inhibited the proliferation, migration, and invasion of HeLa cells, while promoting their apoptosis. Notably, the inhibition by A11 was more significant than that by 20(R)-panaxotriol (p < 0.01) in vivo. Conclusion: To our knowledge, this is the first study to report the production of derivative A11 from 20(R)-panaxotriol and its superior antitumor activity compared to its precursor. Moreover, derivative A11 can be used to further study and develop novel antitumor drugs.

• Journal of the Korean Society of Earth Science Education
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• v.6 no.2
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• pp.145-151
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• 2013

The aim of this research is clarify the relationship between concept understanding degree about the environment and environmental sensitivity and heighten understanding of environmental education target to pre-service elementary teacher. The subjects of this study are science education intensive course 65 students of B educational university. Concept understanding degree about the environment was separately investigated by 'the definition of environmental education', 'Write The positive concept of the natural environment education and briefly describe.''The negative concept of the natural environment education and briefly describe'. Next clarify the relationship between concept understanding degree about the environment and environmental sensitivity target to pre-service elementary teacher. Based on these results, propose an alternative to cultivate pre-service elementary teacher's knowledge about environmental education. Degree of understanding of the concept environmental education research results are as follows. First, Cognition degree about definition of environmental education of pre-service elementary teacher is correctly recognized generally. Second, They do not think deeply about natural environment when it comes to the positive concept of the natural environment of pre-service elementary teacher. Third, They have only a little interest in natural environment when it comes to the negative concept of the natural environment of pre-service elementary teacher. Correlation research results of degree of understanding of the concept of environmental and environmental sensitivity are as follows. High understanding degree of environmental education is high environmental sensitivity. Heighten environmental sensitivity of pre-service elementary teacher will be sustainable environmental education so education is necessary for environmental Sensitivity training.

• Korean Journal of Child Education & Care
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• v.18 no.4
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• pp.227-245
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• 2018

Objective: In this study, educational activities were organized to emphasize the importance of natural disaster safety education by reflecting the recent rapid increases in natural disasters. The study focused on story-sharing, art, and game activities to effectively conduct natural disaster safety education for four-year-old children, and in doing so, aimed to improve the children's safety problem-solving abilities and eco-friendly attitude. Methods: Based on the types of natural disasters that are handled by the Ministry of Public Administration and Security and the Chungcheongbuk-do Office of Education, earthquakes, yellow dust, heat waves, floods, typhoons, bolts of lighting, fires, snowstorms, and global warming were included as the study's educational contents, and a total 20 sessions of natural disaster safety education activities were planned. For the subjects, 20 four-year-old children at K Kindergarten attached to a school were selected as an experimental group and 20 four-year-old children at N Kindergarten attached to a school were selected as a control group. Both kindergartens were located in C City, Chungcheongbuk-do. The experimental group was instructed to perform the study's education activities, whereas the control group only carried out general activities based on the Nuri Curriculum's subjects of daily life. Results: As a result, the children in the experimental group, who received the natural disaster safety education, improved their safety problem-solving abilities and eco-friendly attitude when compared to those in the control group. This outcome proved that the natural disaster safety education conducted by the present study offers educational activities that can positively affect improvements in children's safety problem-solving abilities and eco-friendly attitude. Conclusion/Implications: Therefore, the present study is likely to provide concrete information to teachers who plan to conduct natural disaster safety education in the actual early childhood education field.

• Bulletin of the Korean Chemical Society
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• v.35 no.7
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• pp.2165-2168
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• 2014

• Research in Mathematical Education
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• v.8 no.1
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• pp.31-37
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• 2004

This study explores the relations between mathematics and the natural human language. At the very outset, a general definition of language was, given while it was attempted to make some comparisons between the words of natural language and mathematical symbols at that. Besides, the occupation of natural language functions within mathematics was handled. Consequently, it was tried to manifest that the language of mathematics enjoys the features of natural language as well. Mathematics makes use of many functional and structural features. The fact that fundamental ingredient of mathematics is symbols does not change this reality.

• Bulletin of the Korean Chemical Society
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• v.30 no.11
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• pp.2779-2781
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• 2009