• Title/Summary/Keyword: National Taiwan Normal University

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The in vivo photothermal treatment of gold nanorod in the mouse ear model

  • Liu, Bruce Yao Wen;Chen, Cheng-Lung;Lee, Shin-Yu;Chang, Fu-Hsiung;Lin, Win-Li;Chia, Chih-Ta;Chen, Yang-Yuan
    • Biomaterials and Biomechanics in Bioengineering
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    • v.1 no.1
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    • pp.41-50
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    • 2014
  • Gold nanorod's exceptional light to heat transduction is a robust phonomenon that has been extensively verified. The phenomenon is a trait from which many novel applications across disciplines have been proposed. In this investigation, the feasibility of utilizing heat harvested from such photothermal method to combat cancer is presented. Using non-invasive laser methods, an in vivo study is conducted on mouse ear tumors administered with gold nanorods (Au NRs). An emphasis is placed on monitoring the tumor developments after photothermal treatments, over time. The findings reveal significant tumor growth surpression at a threshold laser power of $0.6W/cm^2$ lasting 2 minutes; this energy also brought about dramatic size reduction in treated tumors. Furthermore, the apparent formation of an eschar over the laser treated region indicates extensive hemorrhagic necrosis of the tumor tissue; a phenomenon implicative to the inhibition of angiogenesis.

Science Teacher Education in Taiwan

  • Lin, Huann-Shyang
    • Journal of The Korean Association For Science Education
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    • v.22 no.5
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    • pp.1071-1081
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    • 2002
  • This article describes the status of science teacher education in Taiwan. The pre-service and in-service science teacher training system, institutes, curricula, programs, and evaluation on the institutes were briefly introduced. The differences before and after the 1996 reform of science teacher training system were compared. Finally, the attempts and efforts that have been done through the channels of research to promote science teachers' professional development were addressed. These efforts include the Case studies of exemplary science teachers' teaching performances, the development of licensure instruments for the certification of science teachers, the use of computers and distance education for supervising student teachers, the exploration of promoting science teachers' understanding about the nature of science, the exploration of promoting science teachers' pedagogical content knowledge, the exploration of promoting science teachers' ability of increasing effective student-teacher and student-student interactions, and the exploration of effective teaching strategies.

Wind vibration control of stay cables using an evolutionary algorithm

  • Chen, Tim;Huang, Yu-Ching;Xu, Zhao-Wang;Chen, J.C.Y.
    • Wind and Structures
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    • v.32 no.1
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    • pp.71-80
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    • 2021
  • In steel cable bridges, the use of magnetorheological (MR) dampers between butt cables is constantly increasing to dampen vibrations caused by rain and wind. The biggest problem in the actual applications of those devices is to launch a kind of appropriate algorithm that can effectively and efficiently suppress the perturbation of the tie through basic calculations and optimal solutions. This article discusses the optimal evolutionary design based on a linear and quadratic regulator (hereafter LQR) to lessen the perturbation of the bridges with cables. The control numerical algorithms are expected to effectively and efficiently decrease the possible risks of the structural response in amplification owing to the feedback force in the direction of the MR attenuator. In addition, these numerical algorithms approximate those optimal linear quadratic regulator control forces through the corresponding damping and stiffness, which significantly lessens the work of calculating the significant and optimal control forces. Therefore, it has been shown that it plays an important and significant role in the practical application design of semiactive MR control power systems. In the present proposed novel evolutionary parallel distributed compensator scheme, the vibrational control problem with a simulated demonstration is used to evaluate the numerical algorithmic performance and effectiveness. The results show that these semiactive MR control numerical algorithms which are present proposed in the present paper has better performance than the optimal and the passive control, which is almost reaching the levels of linear quadratic regulator controls with minimal feedback requirements.

Empirical Selection of Informative Microsatellite Markers within Co-ancestry Pig Populations Is Required for Improving the Individual Assignment Efficiency

  • Lia, Y.H.;Chu, H.P.;Jiang, Y.N.;Lin, C.Y.;Li, S.H.;Li, K.T.;Weng, G.J.;Cheng, C.C.;Lu, D.J.;Ju, Y.T.
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.5
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    • pp.616-627
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    • 2014
  • The Lanyu is a miniature pig breed indigenous to Lanyu Island, Taiwan. It is distantly related to Asian and European pig breeds. It has been inbred to generate two breeds and crossed with Landrace and Duroc to produce two hybrids for laboratory use. Selecting sets of informative genetic markers to track the genetic qualities of laboratory animals and stud stock is an important function of genetic databases. For more than two decades, Lanyu derived breeds of common ancestry and crossbreeds have been used to examine the effectiveness of genetic marker selection and optimal approaches for individual assignment. In this paper, these pigs and the following breeds: Berkshire, Duroc, Landrace and Yorkshire, Meishan and Taoyuan, TLRI Black Pig No. 1, and Kaohsiung Animal Propagation Station Black pig are studied to build a genetic reference database. Nineteen microsatellite markers (loci) provide information on genetic variation and differentiation among studied breeds. High differentiation index ($F_{ST}$) and Cavalli-Sforza chord distances give genetic differentiation among breeds, including Lanyu's inbred populations. Inbreeding values ($F_{IS}$) show that Lanyu and its derived inbred breeds have significant loss of heterozygosity. Individual assignment testing of 352 animals was done with different numbers of microsatellite markers in this study. The testing assigned 99% of the animals successfully into their correct reference populations based on 9 to 14 markers ranking D-scores, allelic number, expected heterozygosity ($H_E$) or $F_{ST}$, respectively. All miss-assigned individuals came from close lineage Lanyu breeds. To improve individual assignment among close lineage breeds, microsatellite markers selected from Lanyu populations with high polymorphic, heterozygosity, $F_{ST}$ and D-scores were used. Only 6 to 8 markers ranking $H_E$, $F_{ST}$ or allelic number were required to obtain 99% assignment accuracy. This result suggests empirical examination of assignment-error rates is required if discernible levels of co-ancestry exist. In the reference group, optimum assignment accuracy was achievable achieved through a combination of different markers by ranking the heterozygosity, $F_{ST}$ and allelic number of close lineage populations.

The Development of Multiple Talents : Conceptualization and Empirical Studies (중다지능 이론을 적용한 창의적인 영재 양성교육)

  • Wu, Wu-Tien
    • Proceedings of the Korean Society for the Gifted Conference
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    • 2002.05a
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    • pp.9-30
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    • 2002
  • A 4-year joint research project (1999-2003), entitled "The Development of Multiple Talents (DMT)", has been designed and carrying out under the sponsorship of the National Science Council, R.O.C. (Taiwan). A 3-dimension construct is proposed for the DMT: form of talents (10 forms, mainly based on Gardner′s theory of multiple intelligences), function of talents (3 functions, based on Stemberg′s conception of successful intelligence), and developmental stage (4 stages, from pre-school to senior high). To take an example of its empirical studies, Wu and Chien (2000), based on a renovated conception of personal intelligence, developed the "Personal Intelligence Inventory" (PII). By means of the PII, it was found that there were some personal intelligence differences between gifted and regular pupils: however, gifted group was not as superior as on academic performance to the regular one (Wu '||'&'||' Chien, 2000). It was also found that there were significant relationships between pupils′personal intelligence and school adjustment in both groups (Tsai '||'&'||' Wu, 2000).

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The Development of Multiple Talents: Conceptualization and Empirical Studies

  • Wu, Wu-Tien
    • Journal of Gifted/Talented Education
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    • v.12 no.2
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    • pp.59-69
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    • 2002
  • A 4-year joint research project(1999-2003), entitled "The Development of Multiple Talents(DMT)", has been designed and carrying out under the sponsorship of the National Science Council, R.O.C. (Taiwan). A 3-dimension construct is proposed for the DMT: form of talents (10 forms, mainly based on Gardner's theory of multiple intelligences), function of talents (3 functions, based on Sternberg's conception of successfulintelligence), and developmental stage (4 stages, from pre-school to senior high). To take an example of its empirical studies, Wu and Chien (2000), based on a renovated conception of personal intelligence, developed the "Personal Intelligence Inventory" (PII). By means of the PII, it was found that there were some personal intelligence differences between gifted and regular pupils; however, gifted group was not as superior as on academic performance to the regular one (Wu & Chien, 2000). It was also found that there were significant relationships between pupils' personal intelligence and school adjustment in both groups (Tsai & Wu, 2000).

Black Hole along with Other Attacks in MANETs: A Survey

  • Tseng, Fan-Hsun;Chiang, Hua-Pei;Chao, Han-Chieh
    • Journal of Information Processing Systems
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    • v.14 no.1
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    • pp.56-78
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    • 2018
  • Security issue in mobile ad hoc network (MANET) is a promising research. In 2011, we had accomplished a survey of black hole attacks in MANETs. However network technology is changing with each passing day, a vast number of novel schemes and papers have been proposed and published in recent years. In this paper, we survey the literature on malicious attacks in MANETs published during past 5 years, especially the black hole attack. Black hole attacks are classified into non-cooperative and collaborative black hole attacks. Except black hole attacks, other attacks in MANET are also studied, e.g., wormhole and flooding attacks. In addition, we conceive the open issues and future trends of black hole detection and prevention in MANETs based on the survey results of this paper. We summarize these detection schemes with three systematic comparison tables of non-cooperative black hole, collaborative black hole and other attacks, respectively, for a comprehensive survey of attacks in MANETs.

Caponization Effects on Growth Performance and Lipid Metabolism in Taiwan Country Chicken Cockerels

  • Chen, Kuo-Lung;Hsieh, Tseng-Yueh;Chiou, Peter Wen-Shyg
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.3
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    • pp.438-443
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    • 2006
  • This trial was designed to study the caponization effects on the appearance, carcass characteristics, blood constituents and lipid metabolism of Taiwan country chicken cockerels. Cockerels were caponized at 8 weeks of age. Sixteen-week-old chickens, including 10 capons, 5 slips (incomplete caponized male chickens) and 20 normal chickens of equal sexes were selected for a 10 week ad libitum feeding trial. Results showed that the testosterone concentrations in the capons and females were lower (p<0.05) than that of intact males. The comb length, height and weights were also lower (p<0.05). The weight of the slips was between that of the capons and intact males, but was heavier (p<0.05) than that of the capon. The live-weight, carcass weight and shank perimeter in the capons were higher than those of the other groups (p<0.05). Hepatic lipogenic enzyme activity analyses showed that NADP-malic dehydrogenase (MDH) activity in the capons and female chickens was higher than that in intact male chickens (p<0.05). The MDH activity in the slips was between that for the capon and intact male chickens (p>0.05). The abdominal fat weight and relative abdominal fat weight of the capons and females were heavier than that for intact males (p<0.05); the slips were between the capons and intact males. The blood lipid content results showed that the triacylglycerol and cholesterol in the capons were higher than that for intact males (p<0.05). However, the percentage of low-density lipoprotein (LDL) was lower than that in intact male chickens (p<0.05). It appears that the increase in lipid accumulation in caponized male chickens is attributed mainly to an increase in MDH activity and the changes in lipid transportation in the capons.

Effects of an Anti-Smoking Program to Prevent Lung Cancer among Urban Aboriginals in Taiwan

  • Lin, Mei-Hsiang;Huang, Sheu-Jen;Shih, Whei-Mei Jean;Wang, Pao-Yu;Lin, Li-Hui;Hsu, Hsiu-Chin
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6451-6457
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    • 2013
  • Background and Purpose: Indigenous people who leave their hometowns and move to the city to earn a living became urban aboriginals. During the process of adapting to urban living situations, they may use various coping strategies such as smoking to overcome their stress. Therefore, it is crucial to provide health education including smoking prevention, increasing knowledge regarding of tobacco hazard, self-efficacy of anti-smoking, and adjusting smoking behavior so as to empower their anti-smoking motivation to prevent lung cancer. The purpose of this study was to explore the effectiveness of an anti-smoking program on urban aboriginals in Taiwan. Methods: A quasi-experimental study design with purposeful sampling was employed. A total of 125 aboriginal subjects were recruited from two local churches at Shu Lin area in northern Taiwan. Subjects were divided into an experimental group (n =64 ) and a control group (n = 61). Both took pre-tests in order to set baseline values, and only the experimental group participated for 3-weeks in the anti-smoking program classes. Both groups took post-tests immediately after the intervention in order to evaluate the immediate effects of the teaching program, and a follow-up test was conducted four weeks after the intervention. Data were analyzed using descriptive statistics, one-way ANCOVA, and repeat measure ANCOVA. Results: After controlling for confounding variables, the results showed that there were statistically significant differences in the self-efficacy of anti-smoking and smoking behavior between experimental and control groups in the immediately post-test and the follow-up test (p < 0.05). However, there was no significant differences in the recognition of hazards of smoking at eiter time point. Conclusions and Implications for Practice: The findings of this study revealed that the anti-smoking program effectively improved self-efficacy of anti-smoking, and decreased the smoking behavior in urban aboriginals. They provide useful information as a reference regarding of aboriginal health promotion to health providers. It is imperative that anti-smoking be reinforced for those regular smokers to prevent induction of lung cancer.