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Earlier treatment improves the chances of complete relief from postherpetic neuralgia

  • Kang, Dong Hee;Kim, Su Young;Kim, Hyuck Goo;Park, Jung Hyun;Kim, Tae Kyun;Kim, Kyung Hoon
    • The Korean Journal of Pain
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    • v.30 no.3
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    • pp.214-219
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    • 2017
  • Background: As herpes zoster progresses via postherpetic neuralgia (PHN) to well-established PHN, it presents its recalcitrant nature to the treatment. At this point, the well-established PHN is fixed as a non-treatable, but manageable chronic painful neuropathic disorder. This study evaluated the incidence of complete relief from PHN according to PHN duration at their first visit, and the other factors influencing it. Methods: A retrospective chart review was performed on patients with PHN at a university-based pain clinic over 7 years. The responders were defined as patients who had complete relief from pain after 1 year of active treatment. Age, sex, PHN duration at their first visit, dermatomal distribution, and underlying disorders were compared in the responder and non-responder groups. Responders were also compared according to these factors. Results: Among 117 PHN patients (M/F = 48/69), 35 patients (29.9%) had complete relief from PHN. Mean ages were $64.3{\pm}10.6$ and $66.9{\pm}10.7$ years, numbers of male to female patients were 11/24 and 37/45, and mean durations of PHN at their first visit were $8.5{\pm}6.3$ and $15.3{\pm}10.7$ months in the responder and non- responder groups, respectively. In addition, PHN patients who visited the clinic before 9 months showed a better result. Dermatomal distribution and underlying disorders did not show significant differences. Conclusions: Almost 30% of PHN patients received complete relief. Those who sought treatment in a pain clinic before 9 months received a better result.

Cell Image Processing Methods for Automatic Cell Pattern Recognition and Morphological Analysis of Mesenchymal Stem Cells - An Algorithm for Cell Classification and Adaptive Brightness Correction -

  • Lim, Kitaek;Park, Soo Hyun;Kim, Jangho;SeonWoo, Hoon;Choung, Pill-Hoon;Chung, Jong Hoon
    • Journal of Biosystems Engineering
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    • v.38 no.1
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    • pp.55-63
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    • 2013
  • Purpose: The present study aimed at image processing methods for automatic cell pattern recognition and morphological analysis for tissue engineering applications. The primary aim was to ascertain the novel algorithm of adaptive brightness correction from microscopic images for use as a potential image analysis. Methods: General microscopic image of cells has a minor problem which the central area is brighter than edge-area because of the light source. This may affect serious problems to threshold process for cell-number counting or cell pattern recognition. In order to compensate the problem, we processed to find the central point of brightness and give less weight-value as the distance to centroid. Results: The results presented that microscopic images through the brightness correction were performed clearer than those without brightness compensation. And the classification of mixed cells was performed as well, which is expected to be completed with pattern recognition later. Beside each detection ratio of hBMSCs and HeLa cells was 95% and 92%, respectively. Conclusions: Using this novel algorithm of adaptive brightness correction could control the easier approach to cell pattern recognition and counting cell numbers.

EVALUATION OF ENTEROCOCCUS FAECALIS REMOVAL EFFICACY OF THE ENDOVAC® AND ENDOACTIVATOR® INTRACANAL IRRIGATION METHODS (EndoVac®과 EndoActivator®를 이용한 근관세척법의 Enterococcus faecalis 제거 효율 평가)

  • Song, Seung-Gon;Park, Se-Hee;Cho, Kyung-Mo;Kim, Jin-Woo
    • Restorative Dentistry and Endodontics
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    • v.34 no.5
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    • pp.390-396
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    • 2009
  • The aim of this study was to evaluate endodontic irrigation methods with $EndoVac^{(R)}$ and $EndoActivator^{(R)}$ in the elimination of Enterococcus faecalis from the root canals. Extracted 70 human single-rooted teeth were used. The canals were instrumented by a crown-down technique with .04 taper ProFile to ISO size 40. After the teeth were autoclaved, the canals were inoculated with E. faecalis and incubated for 48 h. The teeth were randomly divided into three experimental groups of 20 teeth each according to canal irrigation methods and two control groups as follows: group 1 - $EndoVac^{(R)}$; group 2 - $EndoActivator^{(R)}$; group 3-Conventional needle irrigation method. After canal irrigation using 2.5% NaOCl. first samples (S1) were taken using sterile paper point. And the canals were filled with sterile brain heart infusion (BHI) broth and incubated for 24 h, then second samples (S2) were taken. The samples were cultured on BHI agar plate to determine the numbers of colony forming units (CFU). In first sampling (S1), only one canal of conventional method among the all experimental groups was positive cultured. In second sampling (S2), $EndoVac^{(R)}$ group showed the least positive culture numbers of E. faecalis. There was statistically significant difference between the $EndoVac^{(R)}$ and conventional needle irrigation methods in the mean value of Log CFU. According to the results of this study, $EndoVac^{(R)}$ showed better efficacy than conventional needle irrigation method in the elimination of E. faecalis from the root canal.

Congenital Cleft Lip Repair Based on Delaire Philosophy I ; Normal Anatomy and Physiology of the Labionasal Musculature and the Medial Septum of the Nose (Delaire 개념에 기반한 선천성 구순열의 치료 ; 구순 비근육과 비중격의 정상 해부학적 구조 및 생리기전)

  • Yu, Myung-Sook;Eo, Mi-Young;Lee, Suk-Keun;Lee, Jong-Ho;Kim, Soung-Min
    • Korean Journal of Cleft Lip And Palate
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    • v.12 no.2
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    • pp.73-84
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    • 2009
  • The treatment of cleft lip and palate must be based on a complete knowledge of the anatomy, physiology and growth of the involved deformity, because of not only the appearance but also impaired functions such as phonation, mastication, respiration and lingual posture of the maxillomandibular complex. Delaire has long studied all these aspects, and has published many numbers of articles and constructed a philosophy concerning the significance and interrelationship of the various structures. The results obtained from its application seem to be particularly valid from a clinical point of view, although it has not all been scientifically supported by experimental data. For these reasons, Delaire's primary unilateral and bilateral cheilorhinoplasty procedures are particulary good, as is his secondary gingivoalveoloplsty procedure during the course of the surgical repair of the hard palate. In order to understand Delaire's philosophy, it is necessary to consider the normal and pathologic anatomy of the structures involved in the deformity, the role of some structures, such as nasal septum, musculature, and tongue, and some functions, such as dental occlusion or nasal respiration, which play important roles in maxillary and particularly premaxillary growth. Despite of important concept and meanings, Delaire's philosophy has not been introduced widely to our Korean cleft surgeons yet. So authors will summarize the basic concepts of Delaire's philosophy according to already published literatures and lectures based on our previous treatment outcomes.

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Study on the Chemical Management - 1. Chemical Characteristics and Occupational Exposure Limits under Occupational Safety and Health Act of Korea (화학물질 관리 연구-1. 산업안전보건법상 관리 화학물질의 특성과 노출기준 비교)

  • Park, Jihoon;Ham, Seunghon;Kim, Sunju;Lee, Kwonseob;Ha, Kwonchul;Park, Donguk;Yoon, Chungsik
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.25 no.1
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    • pp.45-57
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    • 2015
  • Objectives: This study aims to compare the physicochemical characteristics, toxicological data with Occupational Exposure Limits (OELs) of chemicals under the Occupational Safety and Health Act(OSHA) regulated by the Ministry of Employment and Labor of Korea. Methods: Information on chemicals which have OELs on physicochemical characteristics and toxicological data was collected using Material Safety Data Sheet(MSDS) from Korea Occupational Safety and Health Agency(KOSHA) and the Korea Information System for Chemical Safety Management(KISChem) in 2014. Statistical analyses including correlation and simple regression were performed to compare the OELs with chemical characteristics including molecular weight, boiling point, odor threshold, vapor pressure, vapor density, solubility and octanol-water partition coefficient(OWPC) and toxicological data such as median lethal dose($LD_{50}$) and median lethal concentration($LC_{50}$). Results: A total of 656 chemicals have OELs under OSHA in Korea. The numbers of chemicals which have eight-hour time weighted average(TWA) and short term exposure limits(STEL) are 618 and 190, respectively. TWA was significantly correlated with boiling point and STEL was only correlated with vapor pressure among physicochemical characteristics. Solubility and OWPC between "skin" and "no skin" substances which indicate skin penetration were not significantly different. Both $LD_{50}$ and $LC_{50}$ were correlated with TWA, while the $LC_{50}$ was not with STEL. As health indicators, health rating and Emergency Response Planning Guidelines(ERPG) rating as recommended by the National Fire Protection Association(NFPA) and American Industrial Hygiene Association(AIHA) were associated with OELs and reflect the chemical hazards. Conclusions: We found relationships between OEL and chemical information including physicochemical characteristics and toxicological data. The study has an important meaning for understanding present regulatory OELs.

Study on Developing the Equipment of the Time Division System for Rehabilitation in People with Homonymous Hemianopia (동측성 반맹시 환자의 재활치료용 시분할 장치 개발에 관한 연구)

  • Seo, Jae-Myoung;Park, Gune-Ho;Heo, Min-Young;Jung, Ju-Hyun
    • Journal of Korean Ophthalmic Optics Society
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    • v.19 no.3
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    • pp.407-412
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    • 2014
  • Purpose: It is investigated whether the time division system can extend the field without diplopia for people with homonymous hemianopia. Methods: The time division system was manufactured by a modified mini fan and a black cardboard. In order to verify the effectiveness of the equipment, subjects with and without the equipment took part in the experiment to bisect the space and to recognize letters. Results: Subjects with and without the equipment showed +8.91 and +18.14 degrees in the experiment to bisect the space. In the experiment reading the letters and numbers with the equipment, there were 9 percentage point increase in $4{\times}4$ charts and 15 percentage point increase in $6{\times}6$ charts. It turned out that there was a remarkable improvement for the worst group for reading the charts. Conclusions: The time division system is effective in the mobility and orientation for people with homonymous hemianopia.

Effect of veterinary acupuncture (VA) on the eggs-laying rate (침자극(鍼刺戟)이 생식능력(生殖能力) 저하(低下) 닭에 미치는 영향(影響))

  • Kang Dae-Hee;Son Yang-Sun;Ryu Yeon-Hee;Jeon Ik-Soo;Park Hi-Joon;Lim Sabina
    • Korean Journal of Acupuncture
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    • v.20 no.3
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    • pp.1-8
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    • 2003
  • Objectives : To investigate the increasing effect of veterinary acupuncture (VA) on the eggs-laying rate, we carried out the experiment in old hens. Methods : Twenty four old hens (ISA Brown; 1,200 - 1,400 g) over 75 weeks old whose eggs-laying rates were under the 50% for recent 15 days were used. In experimental group, VA treatments were performed seven times during 10 days. Unang point at the end of bilateral wing and Migun point at the tail bone were stimulated about 30 seconds by the stainless steel needle (0.3 mm o.d.). In control group, similar manual stress were performed at same frequency. The numbers of laid eggs were observed for 26 days after the beginning of treatment. Bloods were sampled two times from wing veins during and after the treatment period and serum concentrations of luteinizing hormone (LH) and Estradiol were detected. Results : Eggs-laying rates of experimental group $(34.29{\pm}2.79%)$ were significantly increased than that of control group $(27.56{\pm}2.00%,\;p<0.05)$ with the significant increasing of LH serum concentration in experimental group $(from\;0.77{\pm}0.13\;IU/I\;to\; 1.42{\pm}0.22\;IU/I,\;p<0.05)$. Conclusions : Increasing effect of VA treatment on the eggs-laying rate in old hens were proved in this study, and it may be the first prompt on the experimental investigation and development of VA.

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A GENERIC RESEARCH ON NONLINEAR NON-CONVOLUTION TYPE SINGULAR INTEGRAL OPERATORS

  • Uysal, Gumrah;Mishra, Vishnu Narayan;Guller, Ozge Ozalp;Ibikli, Ertan
    • Korean Journal of Mathematics
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    • v.24 no.3
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    • pp.545-565
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    • 2016
  • In this paper, we present some general results on the pointwise convergence of the non-convolution type nonlinear singular integral operators in the following form: $$T_{\lambda}(f;x)={\large\int_{\Omega}}K_{\lambda}(t,x,f(t))dt,\;x{\in}{\Psi},\;{\lambda}{\in}{\Lambda}$$, where ${\Psi}$ = and ${\Omega}$ = stand for arbitrary closed, semi-closed or open bounded intervals in ${\mathbb{R}}$ or these set notations denote $\mathbb{R}$, and ${\Lambda}$ is a set of non-negative numbers, to the function $f{\in}L_{p,{\omega}}({\Omega})$, where $L_{p,{\omega}}({\Omega})$ denotes the space of all measurable functions f for which $\|{\frac{f}{\omega}}\|^p$ (1 ${\leq}$ p < ${\infty}$) is integrable on ${\Omega}$, and ${\omega}:{\mathbb{R}}{\rightarrow}\mathbb{R}^+$ is a weight function satisfying some conditions.

우리나라 육상 중역기점 전이

  • Choe, Gwang-Seon;Ok, Su-Seok;Won, Ji-Hun
    • Journal of the Korean Geophysical Society
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    • v.4 no.2
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    • pp.121-131
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    • 2001
  • We have established 88 auxiliary gravity reference stations by using two gravitimeters at the observation offices of the Korean meteorological agency and measured the locations by using GPS. All gravity values have been calculated on the basis of the gravity reference point at Pusan National University, thus, they have been established to bge easily converted to new absolute gravity value later. The increased numbers of the gravity reference stations will minimize errors due to measurements, drift correction etc. and increase the accuracy of the gravity data. The result of this research will be used to verify the gravity data which calculated with the relative gravity meter and to inspect relative gravity meters.

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Community Model for Smart TV over the Top Services

  • Pandey, Suman;Won, Young Joon;Choi, Mi-Jung;Gil, Joon-Min
    • Journal of Information Processing Systems
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    • v.12 no.4
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    • pp.577-590
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    • 2016
  • We studied the current state-of-the-art of Smart TV, the challenges and the drawbacks. Mainly we discussed the lack of end-to-end solution. We then illustrated the differences between Smart TV and IPTV from network service provider point of view. Unlike IPTV, viewer of Smart TV's over-the-top (OTT) services could be global, such as foreign nationals in a country or viewers having special viewing preferences. Those viewers are sparsely distributed. The existing TV service deployment models over Internet are not suitable for such viewers as they are based on content popularity, hence we propose a community based service deployment methodology with proactive content caching on rendezvous points (RPs). In our proposal, RPs are intermediate nodes responsible for caching routing and decision making. The viewer's community formation is based on geographical locations and similarity of their interests. The idea of using context information to do proactive caching is itself not new, but we combined this with "in network caching" mechanism of content centric network (CCN) architecture. We gauge the performance improvement achieved by a community model. The result shows that when the total numbers of requests are same; our model can have significantly better performance, especially for sparsely distributed communities.