• Title/Summary/Keyword: Nano-fluid

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A pilot study on measuring the human cortisol using an electronic device (전자소자를 이용한 인간 감성지표 코티졸 검출에 관한 기초연구)

  • Lee, Hee-Jo;Lee, Jung-Hyun;Hwang, Yoo-Sun;Jung, Hyo-Il
    • Science of Emotion and Sensibility
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    • v.14 no.4
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    • pp.531-536
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    • 2011
  • The precise measurement of human emotion is of pivotal importance in the field of emotion science. Based on the perspective of psychoneuroimmunoendocrinology, human emotion is now considered to be measurable by body fluid. The biological molecule cortisol, which is known for the stress hormone, has been widely investigated to help researchers to estimate the stress loaded on human body. Until now, several measurement techniques such as High Performance Liquid Chromatography (HPLC), fluorometric assay, and reverse phase chromatography have been developed. However, since these measurements are expensive, take relatively long time for an operation, and they are not portable, they are not appropriate for POCT (point of care testing). In this paper we demonstrate the performance of a miniaturized-microwave resonant device in the measurement of cortisol. Our method has many advantages in that it requires a small volume of sample, has fast response time, is easy to operate and needs no labeling process. Besides, it will shed a light on the measurement techniques for emotion science.

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Analysis of Gas-to-Liquid Phase Transformation of Hydrogen in Cryogenic Cooling Tube (초저온 냉각튜브 내 수소기체의 액체수소로의 상변환 분석)

  • Lee, Dae-Won;Nguyen, Hoang Hai;So, Myeong-Ki;Nah, In-Wook;Park, Dong-Wha;Kim, Kyo-Seon
    • Korean Chemical Engineering Research
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    • v.56 no.1
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    • pp.49-55
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    • 2018
  • Under the era of energy crisis, hydrogen energy is considered as one of the most potential alternative energies. Liquid hydrogen has much higher energy density per unit volume than gas hydrogen and is counted as the excellent energy storage method. In this study, Navier-Stokes equations based on 2-phase model were solved by using a computational fluid dynamics program and the liquefaction process of gaseous hydrogen passing through a cryogenic cooling tube was analyzed. The copper with high thermal conductivity was assumed as the material for cryogenic cooling tube. For different inlet velocities of 5 m/s, 10 m/s and 20 m/s for hydrogen gas, the distributions of fluid temperature, axial and radial velocities, and volume fractions of gas and liquid hydrogens were compared. These research results are expected to be used as basic data for the future design and fabrication of cryogenic cooling tube to transform the hydrogen gas into liquid hydrogen.

Experimental Study on the Flow Hysteresis Phenomenon in a Supersonic Nozzle (초음속 노즐에서 발생하는 유동 이력현상에 대한 실험적 연구)

  • Nam, Jong-Soon;Kim, Heuy-Dong
    • Journal of the Korean Society of Propulsion Engineers
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    • v.16 no.2
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    • pp.58-64
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    • 2012
  • Hysteresis phenomena in fluid flow systems are frequently encountered in many industrial and engineering applications and mainly appear during the transient processes of change of the pressure ratio. Shock-containing flow field in supersonic nozzles is typically subject to such hysteresis phenomena, but associated flow physics is not yet understood well. In the present study, experimental work has been carried out to investigate supersonic nozzle flows during the transient processes of change in the nozzle pressure ratio. Time-dependent surface wall pressures were measured by a multiple of pressure transducers and the flow field was visualized using a nano-spark Schlieren optical method. The results obtained show that the hysteresis phenomenon is strongly dependent on the nozzle geometry as well as the time scale of the change of pressure ratio.

A Study on Prediction of Effective Thermal Conductivity of Nano-Fluids Using Generalized Self-Consistent Model and Modified Eshelby Model (일반화된 자기일치모델과 수정된 에쉘비 모델을 이용한 나노유체의 등가열전도계수 예측에 대한 연구)

  • Lee, Jae-Kon;Kim, Jin Gon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.37 no.10
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    • pp.887-894
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    • 2013
  • Effective thermal conductivity of nanofluids has been predicted by using generalized self-consistent model and modified Eshelby model, which have been used for analysis of material properties of composites. A nanolayer between base fluid and nanoparticle, one of key factors for abrupt enhancement of thermal conductivity of nanofluids, is included in the analysis. The effective thermal conductivities of the nanofluid predicted by the present study show good agreement with those by models in the literature for the nanolayer with a constant or linear thermal conductivity. The predicted results by the present approach have been confirmed to be consistent with experiments for representative nanofluids such as base fluids of water or ethyleneglycol and nanoparticles of $Al_2O_3$ or CuO to be validated.

Formulation of Sustained Release Granule for Venlafaxine-HCl Using Water-Insoluble Polymer (수불용성 고분자를 이용한 염산벤라팍신의 서방형 과립 설계)

  • Park, Ji-Seon;Seo, Jin-A;Jeong, Sang-Young;Yuk, Soon-Hong;Shin, Byung-Cheol;Hwang, Sung-Joo;Cho, Sun-Hang
    • Journal of Pharmaceutical Investigation
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    • v.37 no.2
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    • pp.101-106
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    • 2007
  • Venlafaxine, 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl] cyclohexanol hydrochloride is a novel, nontricyclic antidepressant. venlafaxine is a unique antidepressant that differs structurally from other currently available. The aim ot the study was to formulate sustained-release venlafaxine granules and assess their formulation variables. It consists of two layers, venlafaxine drug layer and sustained release coating layer and manufactured by fluidized bed process. The sustained release of drug could be increased by double-control rising various components in venlafaxine drug layer and sustained-release layer. The drug-containing granules were coated with cellulose acetate, cetyl alcohol and Eudragit RS along with plastisizer such as dibuthyl sebacate as an nano-pore former The release oi venlafaxine depended on the type of Eudragit such as RS, and RL used in the formulation of controlled release layer. These results obtained clearly suggest that the sustained release oral delivery system for venlafaxine could be designed with satisfying drug release profile approved.

Application of Graphene Platelets on Electronic Controlled Thermostat of TGDI Engine for Improving Thermal Sensitivity (TGDI엔진용 전자식 수온조절기의 감온성능 향상을 위한 그래핀 소재의 적용)

  • Kim, SeoKyu;Kim, YongJeong;Joung, Heehwa;Jeon, Wonil;Jeong, Jinwoo;Jeong, SooJin
    • Transactions of the Korean Society of Automotive Engineers
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    • v.25 no.1
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    • pp.66-73
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    • 2017
  • In this work, graphene platelets were introduced into wax in an automotive electronic controlled thermostat for the purpose of enhancing its thermal-conductive property and improving response performance. Graphene content ranging from 10 % to 20% was added into and mixed with the wax to investigate the effect of graphene amounts on the performance of an automotive electronic controlled thermostat in terms of response time, hysteresis and melting temperature. The experimental results revealed that graphene in wax contributed to a reduction in the response time and hysteresis of an automotive electronic controlled thermostat. As a consequence, important improvement in thermal sensitivity, full lift, melting temperature and hysteresis were obtained. The thermal response of wax with graphene content of 20 % was improved by 25 %, as compared to that of wax with Cu content of 20 %. Hysteresis of wax with graphene was reduced by $0.6^{\circ}C$ as compared to that of wax with Cu content. The melting temperature of wax is lowered and hysteresis is also improved with increased graphene content of wax in an electronic controlled thermostat. We hope that this study can help further the transition of nano-fluid technology from small-scale research laboratories to industrial application in the automotive sector.

Study on the Grinding Characteristic of MWCNT and Al2O3 Composite by Using Planetary Ball Mill (유성 볼밀을 사용한 MWCNT와 Al2O3의 혼합 분쇄 특성에 관한 연구)

  • Seo, Chang-Myung;Kim, Yeong-Geun;Ji, Myoung-Kuk;Jeong, Hyo-Min;Chung, Han-Shik
    • Journal of Power System Engineering
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    • v.17 no.1
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    • pp.91-96
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    • 2013
  • The present paper focuses on the fabrication of materials with higher thermal conductivity. Nanofluid is a novel transfer prepared by dispersing nanometer-sized solid particles in traditional heat transfer fluid to increase thermal conductivity and heat transfer performance. The purpose of this study is making the nano-size particle. The experiment of MWCNT and $Al_2O_3$ was carried out using a planetary ball mill at several rotation speeds: 200 ~ 400 rpm. The results were examined using scanning electron microscope(SEM). In the case of the MWCNT, it could be more grinding into the small particle in the dry condition and it confirm in the case of the $Al_2O_3$ to be more grinding into the small particle contrary to the MWCNT in the wet condition. In the mixture grinding result of MWCNT and $Al_2O_3$, the dry condition showed the good result in low rotation speed than the wet condition.

Acoustic responses of natural fibre reinforced nanocomposite structure using multiphysics approach and experimental validation

  • Satankar, Rajesh Kumar;Sharma, Nitin;Ramteke, Prashik Malhari;Panda, Subtra Kumar;Mahapatra, Siba Shankar
    • Advances in nano research
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    • v.9 no.4
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    • pp.263-276
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    • 2020
  • In this article, the acoustic responses of free vibrated natural fibre-reinforced polymer nanocomposite structure have been investigated first time with the help of commercial package (ANSYS) using the multiphysical modelling approach. The sound relevant data of the polymeric structure is obtained by varying weight fractions of the natural nanofibre within the composite. Firstly, the structural frequencies are obtained through a simulation model prepared in ANSYS and solved through the static structural analysis module. Further, the corresponding sound data within a certain range of frequencies are evaluated by modelling the medium through the boundary element steps with adequate coupling between structure and fluid via LMS Virtual Lab. The simulation model validity has been established by comparing the frequency and sound responses with published results. In addition, sets of experimentation are carried out for the eigenvalue and the sound pressure level for different weight fractions of natural fibre and compared with own simulation data. The experimental frequencies are obtained using own impact type vibration analyzer and recorded through LABVIEW support software. Similarly, the noise data due to the harmonically excited vibrating plate are recorded through the available Array microphone (40 PH and serial no: 190569). The numerical results and subsequent experimental comparison are indicating the comprehensiveness of the presently derived simulation model. Finally, the effects of structural design parameters (thickness ratio, aspect ratio and boundary conditions) on the acoustic behaviour of the natural-fibre reinforced nanocomposite are computed using the present multiphysical model and highlighted the inferences.

Microchips and their Significance in Isolation of Circulating Tumor Cells and Monitoring of Cancers

  • Sahmani, Mehdi;Vatanmakanian, Mousa;Goudarzi, Mehdi;Mobarra, Naser;Azad, Mehdi
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.879-894
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    • 2016
  • In micro-fluid systems, fluids are injected into extremely narrow polymer channels in small amounts such as micro-, nano-, or pico-liter scales. These channels themselves are embedded on tiny chips. Various specialized structures in the chips including pumps, valves, and channels allow the chips to accept different types of fluids to be entered the channel and along with flowing through the channels, exert their effects in the framework of different reactions. The chips are generally crystal, silicon, or elastomer in texture. These highly organized structures are equipped with discharging channels through which products as well as wastes of the reactions are secreted out. A particular advantage regarding the use of fluids in micro-scales over macro-scales lies in the fact that these fluids are much better processed in the chips when they applied as micro-scales. When the laboratory is miniaturized as a microchip and solutions are injected on a micro-scale, this combination makes a specialized construction referred to as "lab-on-chip". Taken together, micro-fluids are among the novel technologies which further than declining the costs; enhancing the test repeatability, sensitivity, accuracy, and speed; are emerged as widespread technology in laboratory diagnosis. They can be utilized for monitoring a wide spectrum of biological disorders including different types of cancers. When these microchips are used for cancer monitoring, circulatory tumor cells play a fundamental role.

Effects of Surface Roughness on Contact Angle of Nanofluid Droplet (표면조도가 나노유체 액적의 접촉각에 미치는 영향)

  • Kim, Yeung Chan
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.37 no.6
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    • pp.559-566
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    • 2013
  • The effects of solid surface roughness on the contact angle of a nanofluid droplet were experimentally investigated. The experiments were conducted using the solid surface of a 10 mm cubic copper block and the nanofluid of water mixed with CuO nanoparticles. The experimental results showed that the contact angles of nanofluid droplets were lower than those of water droplets and that the contact angle of the nanofluid droplet increased with the solid surface roughness. Furthermore, it was found that the contact angles of water droplets on the solid surface quenched by both water and the nanofluid were lower than those of water droplets on the pure solid surface. However, significant differences were not observed between the contact angles on the solid surfaces quenched by water and the nanofluid.