• Neonatal Medicine
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• v.28 no.1
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• pp.14-21
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• 2021

Purpose: Premature infants have immature respiratory control and cerebral autoregulation. We aimed to investigate changes in cerebral oxygenation during apnea with and without peripheral oxygen desaturation in premature infants. Methods: This prospective observational study was conducted at Inha University Hospital. Near-infrared spectroscopy (NIRS)-monitored regional cerebral oxygen saturation (rScO₂) and pulse oximeter-monitored peripheral oxygen saturation (SpO₂) were assessed during the first week of life in 16 stable, spontaneously breathing preterm infants. Apneic episodes that lasted for ≥20 seconds or were accompanied by desaturation or bradycardia were included for analysis. The average rScO₂ value during the 5-minute prior to apnea (baseline), the lowest rScO₂ value following apnea (nadir), the time to recover to baseline (recovery time), the area under the curve (AUC), and the overshoot above the baseline after recovery were analyzed. Results: The median gestational age and birth weight of the infants were 29.2 weeks (interquartile range [IQR], 28.5 to 30.5) and 1,130 g (IQR, 985 to 1,245), respectively. A total of 73 apneic episodes were recorded at a median postnatal age of 2 days (IQR, 1 to 4). The rScO₂ decreased significantly following apneic episodes regardless accompanied desaturation. There were no differences in baseline, nadir, or overshoot rScO₂ between the two groups. However, the rScO₂ AUC for apnea with desaturation was significantly higher than that for apnea without desaturation. Conclusion: Cerebral oxygenation can significantly decrease during apnea, especially when accompanied by reduced SpO₂. These results add the evidence for the clinical utility of NIRS in monitoring premature infants.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.30 no.4
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• pp.328-331
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• 2019

A linear frequency modulated pulse train waveform can be cost-effective in achieving high range resolution, and thus the synthetic aperture radar may be benefited by using the mixer output of the received signal. However, the image formation process from a mixer output is vulnerable to errors caused by stop-and-go approximation. In this paper, a nadir-looking imaging radar based on time domain correlation is proposed. Furthermore, to prevent the occurrence of ghosting effect in images, antenna placement on a rotating disk is proposed. Simulation results indicate that ghosting effect can be eliminated by employing the proposed antenna placement structure.

• Journal of Sleep Medicine
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• v.15 no.2
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• pp.55-61
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• 2018

Objectives: Despite the accumulating evidence of the effectiveness of positive airway pressure (PAP) therapy in obstructive sleep apnea (OSA) syndrome, adherence to PAP therapy is not high. Several factors reportedly affect PAP adherence; however, it remains unclear whether patients' symptoms were detrimental to adherence rate. This study is aimed at investigating the relationship between insomnia symptoms and adherence. Methods: Retrospective analyses were performed in 359 patients with OSA (mean age $58.4{\pm}13.2$ years; females, n=80). Logistic regression analyses were performed between PAP adherence with clinical factors and questionnaires, such as Epworth Sleepiness Scale, Insomnia Severity Index, and Beck Depression Inventory (BDI). Results: PAP adherence was defined as the use of PAP for ${\geq}4h$ per night on 70% of nights during 30 consecutive days. The median follow-up time was 55 days (interquartile range, 30-119 days), and 54.3% showed poor adherence. Non-adherent patients showed more severe sleep onset insomnia, higher BDI, and higher nadir oxygen saturation ($SaO_2$). Patients with good adherence had higher apnea-hypopnea index, oxygen desaturation index, and respiratory arousal to total arousal ratio. Sleep onset insomnia [odds ratio (OR)=1.792, p=0.012], BDI (OR = 1.055, p=0.026), and nadir $SaO_2$ (OR=1.043, p=0.040) were independently associated with PAP non-adherence. Conclusions: Not the severity of insomnia but sleep onset insomnia was associated with PAP adherence, as well as depressive mood. It suggests that different interventions for reducing insomnia and depressive mood are needed to increase PAP adherence in patients with OSA.

• Radiation Oncology Journal
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• v.17 no.2
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• pp.136-140
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• 1999

Purpose : Prostate specific antigen (PSA) is a useful tumor marker, which is widely used as a diagnostic index and predictor of both treatment and follow-up result in prostate cancer. A prospective analysis was carried out to obtain the period of PSA normalization and the half life of PSA and to analyze the factors influencing the period of PSA normalization. The PSA level was checked before and serially after radical radiotherapy. Materials and Method : Twen쇼 patients with clinically localized prostate cancer who underwent radical external beam radiotherapy were enrolled in this study. Accrual period was from April 1993 to May 1998. Median follow-up period was 20 months. Radiotherapy was given to whole pelvis followed by a boost to prostate. Dose range for the whole pelvis was from 45 Gy to 50 Gy and boost dose to prostate, from 14 Gy to 20 Gy. The post-irradiation PSA normal value was under 3.0 ng/ml. The physical examination and serum PSA level evaluation were performed at 3 month interval in the first one year, and then at every 4 to 6 months. Results : PSA value was normalized in nineteen patients (95%) within 12 months. The mean period of PSA normalization was 5.3 (${\pm}$2.7) months. The half life of PSA Of the nonfailing patients was 2.1 (${\pm}$0.9) month. The nadir PSA level Of the nonfailing Patients waS 0.8 (${\pm}$0.5) ng/ml. The period of PSA normalization had the positive correlation with pretreatment PSA level (R$^{2}$=0.468). The nadir PSA level had no definite positive correlation with the pretreatment PSA level (R$^{2}$=0.075). The half life of serum PSA level also had no definite correlation with pretreatment PSA level (R$^{2}$=0.029). Conclusion :The PSA level was mostly normalized within 8 months (85%). If it has not normalized within 12 months, we should consider the residual disease in prostate or distant metastasis. In 2 patients, the PSA level increased 6 months or 20 months before clinical disease was detected. So the serum PSA level can be used as early diagnostic indicator of treatment failure.

• Journal of international Conference on Electrical Machines and Systems
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• v.3 no.2
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• pp.162-168
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• 2014

Use of nonlinear loads, such as power converters, fluorescent lamps and adjustable speed motor drives, is expected to grow rapidly. All of these loads inject harmonic currents. This paper presents the active filtering of the harmonic distortion generated by the compact fluorescent lamps (CFL). The Instantaneous active and reactive power theory (the p-q Theory) is used to design the control of parallel active filter. The control scheme has been verified using Matlab/Simulink with SimPower Systems through a set of simulation tests under different load conditions. Also, the tuning of the active power filter is performed to improve the quality of the electrical power supply.

• Journal of international Conference on Electrical Machines and Systems
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• v.3 no.2
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• pp.110-115
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• 2014

The reconfigurability of FPGA devices allows designers to evaluate, test and validate a new control algorithm; a new component or prototypes without damaged the real system with the so-called hardware co-simulation. The present paper uses the Xilinx System Generator (XSG) environment to establish and validate a new nonlinear estimator for the rotor time constant inverse that will be exploited to improve the indirect rotor field control of induction motor.

• The Korean Journal of Ecology
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• v.13 no.1
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• pp.59-66
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• 1990

Changes in water potential, lethal temperature and carbohydrate content in the leaves of wintergreen (Pyrola japonica) during overwintering were investigated. Leaf water potential was kept at -2 bars in the tender stage before October, decreased to -46 bars in the dormancy stage and increased to -2 bars again after dehardening Lethal temperatures of the leaf tissue were $-7^{\circ}C$ in the tender stage and $-7^{\circ}C$ in the dormancy stage, but did not recover up to that of the tender stage during dehardeding. Peak of soluble sugar content coincided with the nadir of the leaf water potential. There were close relationships among daily minimum air-temperature, leaf water potential and lethal temperature in changing patterns during overwintering.

• Proceedings of the KSRS Conference
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• 2002.10a
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• pp.542-542
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• 2002

Geometric correction is a critical step to remove geometric distortions in satellite images. For correct geometric correction, Ground Control Points (GCPs) have to be chosen carefully to guarantee the quality of corrected satellite images. In this paper, we present an automatic approach for geometric correction by constructing GCP Chip database (GCP DB) that is a collection of pieces of images with geometric information. The GCP DB is constructed by exploiting Landsat's nadir-viewing property and the constructed GCP DB is combined with a simple block matching algorithm for efficient GCP matching. This approach reduces time and energy for tedious manual geometric correction and promotes usage of Landsat images.

• Journal of Electrical Engineering and Technology
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• v.8 no.6
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• pp.1371-1379
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• 2013

Application of induction machines in wind turbine driven generators is a good alternative due to their good characteristics such as efficiency, reliability and low cost. Nevertheless, when isolated operation is required, the application of external capacitive bank, connected to the stator windings, to provide self-excitation results in a rather complex analysis. This paper presents an analysis of self-excited induction generator connected to a load either directly or by an intermediate of a power converter. At first a dynamic model of the induction generator accounting for magnetic saturation is developed. Then a number of balanced and unbalanced capacitors, passive and active loads are verified. Experimental results obtained from laboratory tests are compared to those simulated; the two are shown to be in good agreement.

• Annals of Clinical Neurophysiology
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• v.10 no.1
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• pp.70-73
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• 2008

By definition, the time to reach nadir in Guillain-Barre syndrome (GBS) is within four weeks. This is in contrast to the chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), which progress for at least two months. However, CIDP can take a relapsing and remitting form and could mimic treatment related fluctuations of GBS (GBS-TRFs) especially during the early phase of disease. We report a patient with CIDP who initially presented with a rapidly progressive limb weakness mimicking GBS, but finally showed good recovery after long term corticosteroid therapy.