• Title/Summary/Keyword: NT2

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Diagnostic Usefulness of N-Terminal Probrain-type Natriuretic Peptide to Detect Congestive Heart Failure Patients (울혈성 심부전 환자에서 N-Terminal Probrain-type Natriuretic Peptide의 진단적 유용성)

  • Son, Gye-Sung
    • Korean Journal of Clinical Laboratory Science
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    • v.37 no.2
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    • pp.88-95
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    • 2005
  • Even though the echocardiograph has been recognized as the method of choice among various diagnostic tools to detect congestive heart failure (CHF), there were some limitations in relation to the consumption of time, labor and process. We analyzed results of N-terminal probrain-type natriuretic peptide (NT-proBNP) and various parameters of the echocardiographic findings to clarify the diagnostic usefulness of NT-proBNP in detecting patients with CHF. We analyzed the sera from total of 242 cases from in-patients and out-patients, which were requested from the cardiovascular section of department of Internal Medicine at Chungnam National University Hospital from March 2003 to May 2004. The procedures were performed in order as shown below; sampling, NT-proBNP analysis, data acquisition and data analysis. All data including personal information and echocardiographic findings ware acquired by medical record review. When classifying the study population into six groups according to the degree of left ventricular ejection fraction (LVEF), the serum level of NT-proBNP was higher in the group with 51-60% of LVEF (P=0.023). There were low correlation between the serum level of NT-proBNP and various parameters of the echocardiographic findings with LVESD (r=0.1513), LVEDD (r=0.0831), LVEF (r=0.2035), IVST (r=0.03) and LVPWT (r=0.0728), respectively. When comparing NT-proBNP with atrial and/or ventricular enlargement, the patient group with both left atrial and left ventricular enlargement (p=0.186) or only left atrial (p=0.105) or only left ventricular enlargement (p=0.256) showed higher level of NT-proBNP without statistical significance than patient group with no enlargement. Searching the optimal cutoff of the serum level of NT-proBNP, the sensitivity (98.9%) and the specificity (100%) was highest at the cutoff of 300 pg/mL than any other cutoffs. These findings suggested that the analysis of NT-proBNP in serum might detect the patients with CHF earlier than with the echocardiograph, especially in patients with asymptomatic or mild symptomatic CHF. In conclusion, NT-proBNP test was proved to be clinically useful to diagnose CHF patients.

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Changes in Physical Properties Especially, Three Phases, Bulk Density, Porosity and Correlations under No-tillage Clay Loam Soil with Ridge Cultivation of Rain Proof Plastic House

  • Yang, Seung-Koo;Seo, Youn-Won;Kim, Sun-Kook;Kim, Byeong-Ho;Kim, Hee-Kwon;Kim, Hyun-Woo;Choi, Kyung-Ju;Han, Yeon Soo;Jung, Woo-Jin
    • Korean Journal of Soil Science and Fertilizer
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    • v.47 no.4
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    • pp.225-234
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    • 2014
  • This study was carried out to investigate the sustainable agriculture of no-tillage technique including recycling of the ridge and the furrow of a field for following crops in Korea. No-tillage systems affect soil physical properties such as three phase (solid, liquid, and air phase) and distribution of soil granular. Solid ratio of subsoil in 3-year of no-tillage (NT) treatment was remarkably lower than that in conventional (CT, 2-year of no-tillage + 1-year of tillage) treatment, while air ratio of subsoil in NT remarkably increased. Bulk density of subsoil in NT remarkably decreased. Porosity of subsoil in NT remarkably increased. Deviation of air phase, bulk density, and porosity of top soil and subsoil in NT remarkably decreased in NT compared with CT. Solid phase ratio and liquid phase ratio in NT and CT had positive (+) correlation. Solid phase ratio and air phase ratio in NT and CT had negative (-) correlation, also liquid phase ratio and air ratio had negative (-) correlation. Bulk density and liquid ratio in soil had positive (+) correlation at top soil and subsoil in NT. Bulk density and air ratio in soil had negative (-) correlation in NT and CT. Porosity and liquid phase ratio had negative (-) correlation, r =1), the significant value was lower in NT than in CT. Porosity and air phase ratio had positive (+) correlation (r =1).

Comparisons of Developmental Potential and Gene Expression Level in Porcine Nuclear Transfer, Parthenogenetic and Fertilized Embryos

  • Kim Jung-Gon;Kumar B. Mohana;Cho Sung-Keun;Ock Sun-A;Jeon Byeong-Gyun;Balasubramanian S.;Rho Gyu-Jin;Choe Sang-Yong
    • Reproductive and Developmental Biology
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    • v.30 no.2
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    • pp.125-133
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    • 2006
  • This study was conducted to detect the apoptosis incidence in blastocysts and to compare the abundance of Bax, Bcl2L1, VEGF and FGFR2 in in vitro fertilized (IVF), parthenogenetic (PAT) and nuclear transfer (NT) embryos. Oocytes matured for 40 hr were enucleated and reconstructed with confluenced fetal fibroblasts (FFs) derived from a ${\sim}45$ day fetus. Reconstructed eggs were then fused with 2 DC pulses (2.0 kV/cm, $30{\mu}sec$) and cultured with $7.5{\mu}g/ml$ cytochalasin B for 3 hr. Parthenotes (PAT) were produced with the same electric strength and culture for NT eggs. The embryos were cultured in NCSU-23 medium at $39^{\circ}C,\;5%\;CO_2,\;5%\l;O_2$ in air. In 3 runs, set of 10 embryos at the 4-cell to blastocyst stages were used to extract total RNA for analyzing the gene expression patterns of pro-apoptotic (Bax), anti-apoptotic (Bcl2L1), vasculogenesis (VEGF), implantation (FGFR2III) using real-time quantitative PCR. Cleavage and blastocyst rates were significantly higher (P<0.05) in IVF and PAT ($79.3{\pm}8.5\;and\;25.5{\pm}6.1,\;and\;85.0{\pm}6.4\;and\;38.6{\pm}5.5$, respectively)than NT counterparts ($65.1{\pm}5.2\;and\;15.6{\pm}3.0$, respectively). Significantly higher (P<0.05) total cells were observed in IVF controls and PAT ($34.7{\pm}5.8\;and\;38.1{\pm}4.1$) than NT embryos ($24.8{\pm}3.2$). Apoptosis index was significantly lower (P<0.05) in IVF than NT embryos. The Relative abundances (RA) of Bax and VEGF were significantly higher (P<0.05) at blastocyst stage in NT than IVF control. The RA of Bcl2L1 and FGFR2III were significantly higher (P<0.05) at blastocyst stage in IVF than NT. The present study observed the abnormal gene expressions in NT embryos at various developmental stages, suggesting certain clues to find out the cause of the low efficiency of NT to term.

Effects of Food Waste Mixed Organic Fertilizer Treatment on Growth and Yield of Capsicum annuum

  • Ho-Jun Gam;Yosep Kang;Eun-Jung Park;Seong-Heon Kim;Sang-Mo Kang;In-Jung Lee
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2022.10a
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    • pp.109-109
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    • 2022
  • The global population is increasing every year, and the amount of food waste is also increasing. Direct landfilling of food waste has been prohibited since 2005, and in accordance with the London Convention in 2013, the discharge of livestock manure, sewage sludge, and food waste into the sea is prohibited. In the case of incineration to treat the discharged food waste, the heat point is lowered due to the moisture in the food waste itself, so fuel must be added. Therefore, this study was conducted to get basic data for setting the limit of application by investigating the growth and yield of crops after treating food waste dry powder mixed fertilizer (MF) on red pepper. In the experiment, continuous cultivation was carried out for two years in 2021 (1st year) and 2022 (2nd year). The treatment groups were set as Not Treatment (NT), Chemical Fertilizer (CF), Mixed Fertilizer (MF), Mixed Fertilizer×2 (MF×2). After harvest, crop growth and yield were investigated. As a result of the 1st years of growth survey, CF, MF, MF×2 show significant difference in shoot length compared to NT. About fresh weight and dry weight, CF show significant difference compared to NT. The 2nd years of growth survey, the shoot and root length, fresh weight did not show significant difference with NT. In case of dry weight, MF is significant increased compared to NT. As a result of the yield survey of the 1st year, all treatment groups did not show a significance in yield compared to the NT. In case of 2nd year, all treatment groups show significantly increased value compared to NT. The yield of MF was highest among the treatment groups. In the future, it is thought that it is necessary to quantitatively evaluate the effect of food waste dry powder mixed fertilizer through additional experiments and continuous cultivation, and to establish an appropriate amount of use and establishment of a manual based on this.

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Dual specificity of $\delta$-endotoxins produced by newly isolated Bacillus thuringiensis NT0423 (새로 분리한 Bacillus thuringiensis NT0423균주의 내독소 단백질에 대한 이중 특이성)

  • 김호산;박현우;김상현;유용만;서숙재;강석권
    • Korean journal of applied entomology
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    • v.32 no.4
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    • pp.426-432
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    • 1993
  • Thirteen isolates of Bacillus thunngiensls producing parasporal mclusions, obtained from 45 samples of dust and soil of sericultural tarms in Kyeong-ki province, were exammed for their toxicity against larvae of Lepidoptera, Dipwra and Coleoptera. Of these isolates, Bacillus f thuringiensis NT0423 was toxic to bath Lepidoptera, and Dipteran larvae. NT0423 showed that the $LC_{50}$ values against the Lepldaptora, Plutella macuhpennis and the Diptera, Culex pipiens were $1.30\times10^6$ CFU/ml, $2.88\times10^5$ CFU/ml, respectively. The tYPlcal bipyramldal crystals produced by NT0423 composed of protoxms of 130-140kDa encoded by one or more plasm mid-horne genes. Also, plasmid DNA analysis indicated Lhat this isolate has 9 plasmids which d differ with reported several B. thuringiensis strains.

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Effect of Hydrothermal Reaction Conditions on Piezoelectric Output Performance of One Dimensional BaTiO3 Nanotube Arrays (1차원 BaTiO3 나노튜브 어레이의 압전발전성능에 수열합성 반응조건이 미치는 영향)

  • Lee, Jae Hoon;Hyeon, Dong Yeol;Heo, Dong Hun;Park, Kwi-Il
    • Journal of Powder Materials
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    • v.28 no.2
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    • pp.127-133
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    • 2021
  • One-dimensional (1D) piezoelectric nanostructures are attractive candidates for energy generation because of their excellent piezoelectric properties attributed to their high aspect ratios and large surface areas. Vertically grown BaTiO3 nanotube (NT) arrays on conducting substrates are intensively studied because they can be easily synthesized with excellent uniformity and anisotropic orientation. In this study, we demonstrate the synthesis of 1D BaTiO3 NT arrays on a conductive Ti substrate by electrochemical anodization and sequential hydrothermal reactions. Subsequently, we explore the effect of hydrothermal reaction conditions on the piezoelectric energy conversion efficiency of the BaTiO3 NT arrays. Vertically aligned TiO2 NT arrays, which act as the initial template, are converted into BaTiO3 NT arrays using hydrothermal reaction with various concentrations of the Ba source and reaction times. To validate the electrical output performance of the BaTiO3 NT arrays, we measure the electricity generated from each NT array packaged with a conductive metal foil and epoxy under mechanical pushings. The generated output voltage signals from the BaTiO3 NT arrays increase with increasing concentration of the Ba source and reaction time. These results provide a new strategy for fabricating advanced 1D piezoelectric nanostructures by demonstrating the correlation between hydrothermal reaction conditions and piezoelectric output performance.

INFLUENCE OF NICKEL-TITANIUM SPREADER ON THE SEALING ABILITY IN LATERAL CONDENSATION TECHNIQUE (측방가압충전시 Nickel-Titanium spreader의 사용유무가 근관충전효과에 마치는 영향)

  • Min, Kyung-San;Hong, Chan-Ui;Cho, Yong-Bum
    • Restorative Dentistry and Endodontics
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    • v.25 no.3
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    • pp.381-389
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    • 2000
  • Lateral condensation with gutta-percha and sealer has been shown to provide an excellent apical seal; however, the lateral condensation technique has demonstrated less favorable apical leakage results in curved canals when compared with straight canals. Placement of endodontic spreaders to within 1 to 2mm of the root canal working length has been advocated for optimum gutta-percha obturation. Due to their stiffness, stainless-steel(SS) spreaders will often fail to achieve this position in curved canals. Newly marketed nickel-titanium(NT) spreaders may offer an advantage in this regard due to the increased flexibility of these instruments. The purpose of this study was to evaluate the effect of NT finger spreader on the sealing ability in lateral condensation technique, compared with conventional SS finger spreader. Twenty four standardized resin models simulating curved canals(30 degree) were randomly placed into 2 groups and instrumented to a #30 master apical file size with Ni-Ti Profile .04 taper series using step down technique. Each groups was obturated with standardized gutta-percha cone by standard lateral condensation technique using SS finger spreader, NT finger spreader. And then, each model was sectioned horizontally with microtome at 1, 2, 3, 4, 5mm levels from the apex. At each of 5 levels, ratio of the area of gutta-percha was obtained by calculating the area of gutta-percha to the total area of the canal. The data collected were then analyzed statistically using a t test for independent samples. The results as follows ; 1. The total mean ratio of area of gutta-percha was 89.20${\pm}$7.00(%) for SS spreader group. 92.20${\pm}$5.17(%) for NT spreader group. There was statistically significant difference between each group(p<0.05). 2. At 3mm level, the mean ratio of area of gutta-percha was 88.32${\pm}$5.41(%) for SS spreader group, 95.25${\pm}$2.60(%) for NT spreader group. There was statistically significant difference between each group(p<0.05). At 1,2,4mm levels, NT spreader group showed greater mean ratio of area of gutta-percha than SS spreader group, too. But there was no statistically significant difference. 3. At 5mm level, the mean ratio of area of gutta-percha was 91.83${\pm}$3.42(%) for SS spreader group, 87.91${\pm}$3.68(%) for NT spreader group. There was statistically significant difference between each group(p<0.05). This study concluded that the NT spreader demonstrated somewhat favorable apical sealing effect than SS spreader in prepared curved canals. The clinical use of NT spreaders may enhance our ability to create better apical seals in curved canals, but further studies in this area will help clarify some of the remaining areas with which practitioners are concerned, such as compaction forces exerted by NT spreaders.

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Analysis of 4-Nitrotoluene in Water by Gas Chromatography/Mass Spectrometry (기체크로마토그래피/질량분석기에 의한 수질시료 중 4-니트로톨루엔의 분석법 연구)

  • 이희경;권오승;류재천
    • Environmental Analysis Health and Toxicology
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    • v.15 no.1_2
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    • pp.45-51
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    • 2000
  • Analytical method of 4-nitrotoluene (4-NT) in water was developed by 9as chromatography/mass selective detector/selected ion monitoring (GC/MSD/SIM). 4-NT was extracted with diethyl ether. Organic layer was washed with 5 % sodium chloride solution. The influence of solvent and evaporation condition on extraction of 4-NT were examined. The retention time of 4-NT peak was 7.72 min. Coefficient of variation (CV) of 4-NT (ng) within day and day-to-day was ranged from 7.0 to 14.6% and from 7.7 to 20.8%, respectively. Recovery of 4-NT was ranged from 84 to 109%, and detection limit of 4-H was lese than 1 ng/㎖.

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Effect of Rolling Factor on the Growth and Thatch Accumulation in Tall fescue. (Tall fescue의 생육과 thatch 축적에 미치는 압력요인의 영향)

  • 이주삼;윤용범;이강욱;윤익석
    • Asian Journal of Turfgrass Science
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    • v.1 no.1
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    • pp.37-41
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    • 1987
  • Effect of Rolling factor on the growth and thatch accumulation in tall fescue was studied from the viewpoint of estimate the rolling factor to obtain the highest values of growth characters and analysis of thatch accumulation. Rolling factors were 1.82, 3.33, 4.29 and 4.85, respectively. The results are may he summarized as follows ; 1. Rolling factor was affected to obstructive on the growth of tall fescue. Thus, the rolling factor ( RF) had significant negative correlated with the dry weight of plant ( DW ), leaf weight (LW), stem weight (SW), dry weight of thatch (Th), number of tillers (NT) and C / F ratio. 2. Rolling factor of 1.82 was an adequate rolling factor for the growth. 3. The dry weight of thatch(Th) had significant positive correlated with DW, LW, and NT, but negative correlated with the dry weight of thatch per a tiller ( th / NT). 4. Thatch accumulation system can be shown in following diagram. yield compnents - DW ~ Th - Rf (LW, SW, NT, C/F) th/NT 5. The dry weight of thatch per a tiller(th / NT) was a concerning factor for the losses of thatch.

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The Effects of Neuromuscular Electrical Stimulation on Synaptic Reorganization of Neuromuscular Junctions in Rat Atrophic Muscle (신경근 전기자극이 흰쥐 위축근 신경근 연접부의 연접재형성에 미치는 영향)

  • Nam, Ki-Won;Kim, Young-Eok
    • The Journal of Korean Physical Therapy
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    • v.19 no.3
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    • pp.19-30
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    • 2007
  • Purpose: This study was performed to investigate the effects of NMES for recovery of skeletal muscle. Methods: The normal group consisted of healthy rat without cast immobilization. The control group was breeding at standard cage during 7 days after 2 weeks-cast immobilization on hind limb. The experimental group. I. received NMES application during days after 2 weeks-cast immobilization on hind limb. The effects were measured with NT-3 immunoreactivity in neuromuscular junction by light microscope. Results: Immunoreactivity of NT-3 at the neuromuscular junction was higher appeared experimental groups than control group. Then, There was a little detection in the normal and control group. Conclusion: These therapeutic interventions enhance expression of NT-3 at the neuromuscular junction. Also, NMES is considered to effect on a normal structural formation and NT-3 expression at the neuromuscular junction.

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