• Title/Summary/Keyword: NPD

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Limiting the Number of Open Projects to Shorten the NPD Schedule

  • Wang, Miao-Ling;Yang, Chun-I;Chang, Sheng-Hung
    • Industrial Engineering and Management Systems
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    • v.10 no.1
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    • pp.34-42
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    • 2011
  • Many companies open multiple projects simultaneously due to market trends, which results in a crowding out effect because of limited resources. R&D engineers become overloaded and scheduling of product development is delayed resulting in timing misses and lost sales leads. The company in this case study (Company A), often opens up many projects simultaneously in order to respond to market needs quickly. The engineers are overloaded and, of course, the schedule is delayed. In order to identify problems, Company A began using Dr. Goldratt's Thinking Processes (TP) during new product development (NPD). When the analysis phase of TP was completed, Company A's core problem was identified as "the quantity of kick-off projects." Consequently, new rules and conditions and procedures were proposed for the opening, suspending, stopping, and closing of projects. Finally, the "Future Reality Tree" ensured that the proposed rules, conditions and procedures were set up as an available solution approved for practical application by executives. After a one-year trial run, the results showed that the Project Duration Rate was reduced by 53%, the Project Closed Rate was increased by 140% and the Project on Time Rate was increased from 10% to 68%. The above results give significant evidence of the benefits of the proposed methodology.

A Case of Nocturnal Paroxysmal Dystonia: Frontal Lobe Epilepsy and Parasomnias (FLEP) Scale, Polysomnography and Subtraction of Ictal-interictal SPECT Coregistered with MRI (SISCOM) Findings (야간발작성근육긴장이상 1예: 전두엽간질 및 사건수면척도, 수면다원검사, 발작기 및 발작간기 감산 SPECT 소견)

  • Kim, Woojun;Oh, Yun-Sang;Yoon, Bora;Kim, Yeong-In;Lee, Kwang-Soo;Kim, Joong-Seok
    • Annals of Clinical Neurophysiology
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    • v.10 no.1
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    • pp.52-57
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    • 2008
  • Even though the origin and nature of nocturnal paroxysmal dystonia (NPD) remains unclear, it has been considered as a manifestation of the nocturnal frontal lobe epilepsy. We report a 17-year-old man with abnormal stereotyped movement during sleep. Video-EEG monitoring, ictal SPECT and night polysomnography did not show any evidence of epilepsy. However, the partial response to large dose of carbamazepine and the scoring according to the frontal lobe epilepsy and parasomnias (FLEP) scale suggest his events could be classified as epilepsy. Therefore we think the FLEP scale might be a useful tool for differential diagnosis in a patient presenting NPD.

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The Bright and Dark Side of Pre-existing Social Ties and Relational Orientation in Research Collaborations in South Korea

  • HEMMMERT, Martin;KIM, Jae-Jin
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.1
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    • pp.279-290
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    • 2020
  • Informal networks between individuals are widely seen as important in East Asian business systems. However, while the performance implications of guanxi in China have been extensively studied, much less is known on how informal networks may influence business outcomes in other East Asian countries. We examine informal networks in inter-organizational research collaborations in South Korea by studying the role of pre-existing social ties and relational orientation in new product development (NPD) collaborations and university-industry research (UIR) collaborations. We conduct an interview-based, in-depth case analysis of five NPD collaborations and five UIR collaborations. Pre-existing social ties and relational orientation are prevalent in both types of research collaborations. However, they have different consequences for collaboration outcomes. Pre-existing social ties strongly vary in their types and strength, and negatively affect collaboration outcomes unless they result in the selection of competent and motivated partners. Relational orientation manifests itself in a task-related and social exchange between collaboration partners, which contributes to outcomes such as knowledge acquisition and business performance. Korean collaboration managers should rely only on pre-existing social ties that are well-aligned with task-related requirements when initiating and conducting research collaborations. However, the creation of strong relationships between collaboration team members of partnering organizations should be encouraged.

The Role of Structural Holes in Uncertain Environments in Channel Relationships

  • Kim, Min-Jung
    • Journal of Distribution Science
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    • v.16 no.6
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    • pp.25-35
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    • 2018
  • Purpose - Although marketing networks are crucial competitive advantage in terms of firm's new information and resource acquisition ability, their impact on new product development performance remains vague, especially under environmental uncertainty. The principal objective of this research is to provide a better understanding of effects of technological uncertainty and volume uncertainty on first tier supplier's perceived performance of new product development under conditions reflecting varying levels of structural holes. Specifically, this research examines the moderating effect of structural holes on the relationship between environmental uncertainty and new product development performance. Research design, data, and methodology - To test the hypotheses, a questionnaire survey was conducted with a Korean engineering firm's major first-tier suppliers in the context of internal network entities, manufacturer-supplier-subsupplier relationships, and to verify the proposed hypotheses, structural equation modeling was established. Construct measures were based on existing measures and previous research. Results - The survey results indicate that technological uncertainty and volume uncertainty differentially affect NPD performance under conditions of high and low structural holes. Conclusions - This study offer some theoretical and practical implications among distribution channel members, especially, this study suggests that interfirm networks have critical competitive advantage in uncertain environments. The distinctiveness of engineering industry might limit the generalizability of the results. Thus, future research should consider a wider range of industries.

Isolation of Volatiles from Panax ginseng Root by Vacuum-Distillation with Freeze-Drying (동결건조시 감압증류되는 인삼의 휘발성물질의 분리)

  • Park, Hoon;Sohn, Hyun-Joo;Cho, Byung-Goo
    • Journal of Ginseng Research
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    • v.14 no.3
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    • pp.353-356
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    • 1990
  • The isolation of volatile compounds by vacuum-distillation with freeze-drying was tested 1 with fresh ginseng roots. The roots were frozen at-8$0^{\circ}C$; they were dried at-4$0^{\circ}C$ tinder vacuum(40 tory), for 24 hours; and the ice condensed at the silrface of condenser in the freeze-dryer was thauved at room temperature. The ether extract of the resulting aqueous solution was analyzed by gas chromatography (GC) equipped with a flame ionization detector (FID) or a nitrogen-phosphorils detecto(NPD) and by gas : chromatography/mass spectrometry(GC/MS). More than forty peaks were observed in the CG(FID) profile. and more than ten peaks were observed in the GC(NPD) profile. Among them, thirteen components 1including one aldehyde, four hydrocarbons, two esters, folly alcohols, and two vyrazines were identified: six components the molesuiar ions of which were m/z, 204 were estimated to be a series of azulene compounds; and the other components unidentified were estimated to have molecular weights of lower than 254. Therefore, the freeze-drying technicue is thought to be usefu1 for the isolation of volatile compounds of such low molecufilar weights from vegetables, fruits and biological fluids as well as fresh ginseng roots under the tested conditions.

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Efficient white organic light-emitting diodes with a doped hole-blocking layer

  • Ahn, Young-Joo;Kang, Gi-Wook;Lee, Nam-Heon;Lee, Mun-Jae;Kang, Hee-Young;Lee, Chang-Hee
    • 한국정보디스플레이학회:학술대회논문집
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    • 2002.08a
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    • pp.780-783
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    • 2002
  • We report very efficient white OLEDs consisting of a blue-emitting 4,4'bis[N-(1-napthyl)-N-phenyl-amino]-biphenyl (${\alpha}$-NPD), a hole-blocking layer of 2,9-dimethyl-4, 7-diphenyl-1, 10-phenanthroline (BCP) doped with red fluorescent dye of 4-dicyanomethylene-2-methyl-6-[2-(2,3,6,7-tetrahydro- 1H, 5H-benzo[i,j]quinolizin-8-yl) vinyl]-4H-pyran) (DCM2), and green-emitting tris(8-hydroxyquinoline) aluminum ($Alq_3$). The device with the structure of ITO/${\alpha}$-NPD (50 nm)/BCP:DCM2 (0.8 %, 4 nm)/$Alq_3$ (50 nm)/LiF (0.5 nm)/Al shows a white emission with the CIE coordinates (0.329, 0.333). The maximum luminance of 20,800 cd/$m^2$ is obtained at 15.4 V. The power efficiency is 2.6lm/W and the external quantum efficiency is 2.1 % at a luminance of 100 cd/$m^2$ at the bias voltage of 6 V.

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A Study on the Simultaneous Analysis of Regulated Pesticides Residues from Rice and Soy Bean (쌀과 콩 중 규제잔류 농약의 동시분석에 관한 연구)

  • Taek-Jae Kim;Yun-Woo Eo;Jae-Seong Rhee
    • Journal of the Korean Chemical Society
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    • v.35 no.5
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    • pp.560-568
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    • 1991
  • The simultaneous determination method which simply determined regulated pesticides was investigated. Sample was extracted with acetone-methanol and partitioned with methylene chloride after addition of saturated NaCl solution. Entract was purified by Bio-Beads S-X3 column using cyclohexane-methylene chloride (1 : 1) as eluate. The determination of pesticides was performed by BP-1 capillary column gas chromatography using ECD and NPD. The average recoveries of pesticides in rice and soy fbean were over 83% and 81%, respectively. It was possible to detect pesticides in rice up to 0.002 ppm by $\alpha-BHC$ and up to 0.05 ppm by carbaryl and in soy bean up to 0.01 ppm by ${\alpha}$-BHC and up to 0.3 ppm by carbaryl.

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Determination of residual pesticides in crude drugs - Gas chromatographic Analysis of 18 pesticides - (한약재중의 잔류농약 분석 - GC에 의한 18종 잔류농약의 분석 -)

  • Hwang, In-Sook;Choi, Byung-Hyun;Bae, Chong-Ho;Kim, Myung-Hee;Cho, Hae-Jeon
    • Korean Journal of Pharmacognosy
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    • v.32 no.3 s.126
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    • pp.200-211
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    • 2001
  • This study was carried out to determine the 11 organochlorine, 7 organophosphorus residual pesticides in 251 crude drugs. These residual pesticides in herbal drugs were extracted with acetonitrile and the extracts were cleaned up via LC-florisil solid phase extraction column. The prepared samples were assayed for pesticide residues using GC-ECD, NPD with capillary column and identified by GC-MSD. Recoveries were $63.9{\sim}111.5%$ in the organochlorine pesticides and $69.8{\sim}92.4%$ in the organophosphorus pesticides, and detection limits were $0.001{\sim}0.65\;ppm$ in the organochlorine pesticides and $0.0009{\sim}0.0074\;ppm$ in the organophosphorus pesticides. Pesticide residues were detected in 9 cases.

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Analysis of the Optical and Electrical Properties of a White OLEDs Using the newly Synthesized Blue Material (신규 합성 청색재료를 사용한 백색 유기발광소자의 광학적$\cdot$전기적 특성평가)

  • Yoon Seok Beom
    • Journal of the Korea Society of Computer and Information
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    • v.10 no.1 s.33
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    • pp.1-6
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    • 2005
  • White light emission is very important for applying electroluminescent device to full display, backlight and illumination light source. In this letter, Multilayer molecular organic white-light-emitting device using thin nim of blue material nitro-DPVT with fluorescent dye Rubrene for an orange emission were fabricated. The basic structure of the fabricated device is a-NPD / nitro-DPVT / nitro- DPVT:Rubrene / BCP/ Alq3. Aluminum is used as the cathode material and ITO was anode material. The white light emission spectrum covers a wide range of the visible region and the Commission Internationale do I'E clairage (C.I.E.) coordinates of the emitted light was ((0.3347, 0.3515) at 14V. The turn voltage is as low as 2.5V and quantum efficiencies are $0.35\%$.

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Quantitative Analysis of Tiropramide in Human Blood by Gas Chromatography with Nitrogen-Phosphorus Detector

  • Kwon, Oh-Seung;Park, Young-Jin;Ryu, Jae-Chun;Chung, Youn-Bok
    • Archives of Pharmacal Research
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    • v.26 no.5
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    • pp.416-420
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    • 2003
  • The analytical method of antispasmodic agent tiropramide {$(\pm)\alpha$-(benzoylamino)-4-[2-(diethylamino)ethoxy]-N,N-dipropylbenzenepropanamide hydrochloride} was developed by gas chromatography/nitrogen-phosphorus detector (GC/NPD) in human plasma. Two kinds of tiropramide tablets were orally administered to volunteers by Latin square crossover design, and blood was withdrawn as designed schedule. The plasma of 1 mL was loaded on Sep-pak $C_{18}$ cartridge and eluted with methanol after washing with 30% methanol. The residue dissolved in 100 $\mu$L of methanol after evaporation was analyzed by GC/NPD. Precision (CV%) of intra-day was located within 2.6% and accuracy was less than 9.7%. Inter-day precision was below 8.7% and accuracy was relatively good as less than 14%. Plasma samples obtained from human volunteers were analyzed for the determination of tiropramide concentration by using this method. The method was sensitive, rapid and suitable enough to be applied for pharmacokinetic and bioequivalence studies of tiropramide in human volunteers.