• Title/Summary/Keyword: NOESY

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Four New Darnmarane-Glycosidesl Ginsenosides $Rg_5, Rh_4, Rs_3, AND Ff_2$, from Korean Red Ginsengs the Root off]unarm ginseng C. A. Meyer

  • Jong Dae Park;Nam
    • Proceedings of the Ginseng society Conference
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    • 1998.06a
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    • pp.115-126
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    • 1998
  • Four new dammarnae-glycosides named ginsenosides Rgs, Rh4, RsB and Rf2 have been isolated 1'rom Korean red ginseng, the root of Panax ginseng C. A. Meyer (Araliaceae) and their chemical structures have been elucidated by chemical and spectroscopic methods, including'H-'H COSY, HMQC, HMBC, NOESY, as 3-0- [$\beta$-D-glucopyranosyl(1 ~2)-$\beta$-D-glucopyranosyl] dammar-20(22) , B4-diene-3P,12P-diol (ginsenoside Rgs),6-0-$\beta$-D-glucopyranosyl-dammar-20(22),24-diene-3P,6P, 12P-triol (ginsenoside Rh4),3-0- [6" -0-acetyl-D-glucopyranosyl(1 ~2)--D-glucopyranosyl] 20(5)- protopanaxadiol (ginsenoside Rs3) and 6-0- [u-L-rhamno-pyranosyl(1 ~2)-$\beta$-D-glucopyranosyl] dammarane -3$\beta$, 6a, 12 $\beta$, 20(R),25-pentol(ginsenoslde Rfa). The absolute stereo structure of a double bond at C-20(22) was determined as entgegen type by applying NOESY.OESY.

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Two Biophenolic Glycosides from Portulaca oleracea (쇠비름에서 분리된 2개의 Biophenolic Glycosides)

  • Youngwan Seo;Jongheon Shin;Burm Jong Lee;Dong Seok Lee
    • Journal of the Korean Chemical Society
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    • v.47 no.1
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    • pp.43-46
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    • 2003
  • From Portulaca oleracea which is widely distributed in Korea and has long been used as a folk medicine, two biophenolic glycosides, 3-hydroxy-1-(2-hydroxyethyl)phenyl-4-O-${\beta}$-D-glucopyranoside (1) and 2-(3,4-dihydroxyphenyl) ethyl-O-${\beta}$-D-glucopyranoside (2) were isolated using column chromatography and reversed-phase HPLC. $^{13}C$ NMR spectral assignment for these compounds was revised by the extensive 2-D NMR experiments such as NOESY, HMQC, and HMBC. These compounds showed a considerable antioxidant effect in DPPH assay system.

Flavanone Glycoside from the Fruits of Chaenomeles sinensis

  • Kim, Ho-Kyoung;Jeon, Won-Kyung;Ko, Byoung-Seob
    • Natural Product Sciences
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    • v.6 no.2
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    • pp.79-81
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    • 2000
  • Investigation of the fruits of Chaenomeles sinensis (Rosaceae) resulted in the isolation of a minor flavonoid. The structure of flavanone glycoside was determined to be as $2-hydroxynaringenin-7-O-{\beta}-glucoside$ on the basis of FAB-MS and spectral evidence, especially by 2D-NMR $(^1H-^1H\;COSY,\;HMQC,\;HMBC\;and\;NOESY)$.

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Griseusin C, a Novel Quinone Derivative from a Marine-Derived Fungus Penicillium sp.

  • Li, Xiang;Zheng, Yinan;Sattler, Isabel;Lin, Wenhan
    • Archives of Pharmacal Research
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    • v.29 no.11
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    • pp.942-945
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    • 2006
  • A novel quinone derivative, Griseusin C (1), along with a known quinone, Naphthoquinone C (2), was isolated from the lyophilized culture broth of the marine-derived fungus Penicillium sp. The structures were elucidated on the basis of extensive 1D-and 2D-NMR, as well as HRESIMS, spectroscopic analysis. The relative stereochemistries of the compounds were assessed by NOESY analysis.

12-Hydroxyamoorastatone, a New Limonoid from Melia azedarach var. Japonica

  • Jong-Woong Ahn;Geon-Seek Yoo;Zaesung No;Seung-Ho Lee
    • Bulletin of the Korean Chemical Society
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    • v.14 no.5
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    • pp.554-556
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    • 1993
  • A chemical investigation of the stem bark of Melia azedarach var. Japonica (Meliaceae) has led to a new limonoid, 12-hydroxyamoorastatone (1), whose structure has been elucidated by spectroscopic measurements including 2D-NMR. The 2D-NOESY experiment on its di-p-bromobenzoate derivative (1a) has established the relative configuration of 1.

Three Norisoprenoids from the Brown Alga Sargassum thunbergii (갈조류 지충으로부터 분리한 3개의 Norisoprenoids 화합물)

  • Park, Ki-Eui;Kim, You-Ah;Jung, Hyun-Ah;Lee, Hee-Jung;Ahn, Jong-Woong;Lee, Burm-Jong;Seo, Young-Wan
    • Journal of the Korean Chemical Society
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    • v.48 no.4
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    • pp.394-398
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    • 2004
  • From Sargassum thunbergii which is widely distributed in coastal area of Korea, three norisoprenoids, (+)-epiloliolide (1), (-)-loliolide (2), and apo-9'-fucoxanthinone (3) were isolated by using column chromatography and reverse-phase HPLC. Compound 1, 2 and 3 were for the first time isolated from the Brown Alga Sargassum thunbergii. Particularly, Compound 1 was for the first time isolated the marine organism although it was reported from the terrestrial plant. Their structures have been determined by extensive 2-D NMR experiments such as $^1H COSY, NOESY, HMQC$, and HMBC and by comparison with the reported data in the literature.

Two New Sesquiterpenes from Pluchea arguta

  • Ahmad, Viqar Uddin;Zahid, Muhammad;Khatoon, Rasheeda;Ali, Zulfiqar;Abbas, Muhammad;Iqbal, Muhammad Zafar
    • Natural Product Sciences
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    • v.5 no.2
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    • pp.85-87
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    • 1999
  • Two new sesquiterpenes, 3'-chloro-2'-hydroxy-3-epi-arguticinin (1) and argutenol (2) belonging to eudesmane and gorgonane classes respectively, have been isolated from Pluchea arguta. Their structures were elucidated with the help of sophisticated spectroscopic techniques including nOe difference and NOESY experiments.

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Isolation of Magnolialide and Artesin from Cichorium intybus: Revised Structures of Sesquiterpene Lactones

  • Park, Hee-Juhn;Kwon, Sang-Hyuk;Yoo, Ki-Oug;Jung, Won-Tae;Lee, Kyung-Tae;Kim, Joo-Il;Han, Yong-Nam
    • Natural Product Sciences
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    • v.6 no.2
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    • pp.86-90
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    • 2000
  • Two known eudesmanolides, magnolialide and artesin, were isolated from the roots of Cichorium intybus. Their structures were confirmed by HMBC and NOESY NMR spectral interpretation. Therefore, guaianolides and eudesmanolides that have been previously reported should be revised.

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Structural Elucidation of Epicatechin $(4{\rightarrow}7)$ 5,8,3'4'-tetrahydroxy-(2R,3R)-flavan-3-ol Isolated from the Bark of Korean Pine Tree (Pinus densifora)

  • Lim, Yoong-Ho;Yong, Yeun-Joong;Oh, Sung-Jin;Song, Hong-Keun
    • Applied Biological Chemistry
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    • v.41 no.4
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    • pp.265-269
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    • 1998
  • Several flavonoid dimers were isolated and elucidated from the bark of Korean pine tree (Pinus densiflora). One of them was postulated to be a compound, epicatechin $(4{\rightarrow}7)$ 5,8,3',4'-tetrahydroxy-(2R,3R)-flavan-3-ol, whose structural determination was carried out by diverse NMR techniques.

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