• Title/Summary/Keyword: NNDS

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Screening of New Mediators for Lignin Degradation Based on Their Electrochemical Properties and Interactions with Fungal Laccase

  • Shin, Woon-Sup;Cho, Hee-Yeon;Cho, Nam-Seok
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.38 no.5 s.118
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    • pp.1-8
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    • 2006
  • This study was performed to evaluate extensive electrochemical characteristics of 23 commercially available mediators for laccase. Electrochemical properties, interactions with laccases, and ability to degrade lignin were compared for selected mediators. Among them, NNDS has very similar electrochemical properties in terms of reversibility and redox potential (about 470 mV vs. Ag/AgCl at pH=7) compared to ABTS which is a well-known mediator. Specific activity of purified laccase from Cerrena unicolor was determined by both 2,2'-azino-bis-(3-ethylbenz-thiazoline-6-sulfonic acid) (ABTS) and 1-nitroso-2-naphthol -3,6-disulfonic acid (NNDS). The specific activity of the laccase was 23.2 units/mg with ABTS and 21.2 units/mg with NNDS. The electron exchange rate for NNDS with laccase was very similar to that for ABTS, which meant that NNDS had similar mediating capability to ABTS. Determining methanol concentration after reacting with laccase compared to lignin degradation capabilities of both ARTS and NNDS. ARTS or NNDS alone cannot degrade lignin, but in the presence of laccase enhanced the rate of lignin degradation. ABTS showed better activity in the beginning, and the reaction rate of NNDS with lignin was about a half of that of ABTS at 10 minute, but the final concentration of methanol produced in 1 hour was very similar each other. The reason for similar methanol concentration for both ABTS and NNDS can be interpreted as the initial activity of ABTS was better than that of NNDS, but ABTS would be inhibited laccase activity more during the incubation.

Status of national notifiable infectious diseases in Jejudo, Korea: 2011~2018 (제주도 법정감염병 신고 현황: 2001~2018)

  • Kim, Mi Na;Cho, Eun Suk;Kim, Mi Ya;Bae, Jong-Myon
    • Journal of Medicine and Life Science
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    • v.15 no.2
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    • pp.79-83
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    • 2018
  • Jejudo has unique geographical and climatologic characteristics compared with other areas in Korea. The aim was to evaluate differences of the nationwide notifiable infectious diseases (NND) occurred in Jejudo, 2011~2018. The source of data was on the Infectious Disease Statistics System operated by Centers for Diseases Control & Prevention in Korea between 1 January 2001 and 30 September 2018. After calculating the proportion of sum of years showing a higher incidence in Jejudo than nationwide divided by sum of comparing years(PSYH), authors defined the infectious diseases for control in Jejudo (IDCJ) with PSYH over 75%. In addition, the infectious diseases showing increasing trends during recent 2 years(2015~2018) were defined as sudden increase Infectious diseases for control (SIDCJ). IDCJ in 2001~2018 included 3 NNDs such as chicken pox, syphilis, and Streptococcus pneumoniae. The results support main evidences to plan strategies and distribute community resources for control and prevention of NNDs in Jejudo, Korea.

Status of national notifiable infectious diseases in Jeju Province, Korea: 2001~2019 (제주도 법정감염병 신고 현황: 2001~2019)

  • Kim, Mi Na;Jang, Sungryul;Kim, Mi Ya;Bae, Jong-Myon
    • Journal of Medicine and Life Science
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    • v.17 no.2
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    • pp.53-59
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    • 2020
  • Jeju Province has unique geographical and climatologic characteristics compared with other areas in Korea. Thus it needs to evaluate the status of nationwide notifiable infectious diseases(NND) continuously. The aim was to conduct a descriptive study for NNDs in Jeju Province, 2001~2019. The source of data was on the Infectious Disease Statistics System operated by Centers for Diseases Control & Prevention in Korea between 1 September 2001 and 31 August 2019. When calculating the proportion of the sum of years showing a higher incidence in Jeju province than nationwide divided by the sum of comparing years, the NDD with the proportion of the sum of years over 75% in 2001~2019 included varicella and syphilis. The results support significant evidence to plan strategies and distribute community resources for the control and prevention of NND in Jeju Province, Korea.