• 제목/요약/키워드: NEO

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알러젠 제거 옻나무 추출물 투여로 삶의 질이 개선된 불응성 직장암 환자 1례 (Quality of Life Improved with Allergen-removed Rhus Verniciflua Stokes based Traditional Korean Medicine on a Patient with Refractory Rectal cancer : Single Case Report)

  • 김나희;박재우;김경석;정현식;최원철;윤성우
    • 대한암한의학회지
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    • 제13권1호
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    • pp.55-61
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    • 2008
  • Nearly 800,000 new colorectal cancer cases are believed to be occur each year, which account for approximately 10% of all incident cancers, and mortality from colorectal cancer is estimated at nearly 450,000 per year. We report one patient with rectal cancer of stage III. The patient had a rectal cancer(StageIII T3N2M0) and underwent low anterior resection in 2004 followed by chemotherapy and radiotherapy. Lymph node metastases were found in 2005 and the patient was treated by palliative chemotherapy, which could not supress the lymph node metastases increase. The patient visited Kyunghee University East-West Neo Medical Center(KHNMC) in 2006 and was treated using allergen-removed Rhus Verniciflua Stokes(aRVS). Radiotherapy was done simultaneously in 2006. There was no evidence of recurrence since then. The patient showed no side effects. This case report brings forth the importance of a thorough study in rectal cancer in the traditional Korean medical point of view, along with the long-term effect of aRVS.

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<명선록(明善錄)>의 반주자학적 논거의 이제마(李濟馬)의 사상인장이론(四象人臟理論)과의 관련성에 대하여 (The Study on the Relationship Between Sasang Constitutional Theory and Anti-Neo-Confucianism in Myung-Suen Lock)

  • 이항재;최승훈
    • 한국한의학연구원논문집
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    • 제2권1호
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    • pp.289-306
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    • 1996
  • This study are performed to reveal the origin of the Sasang constitutional theory made by Lee-jae-ma(李濟馬), confucianist as well as famous oriental doctor, who succeeded to Han- suck-jie(韓錫地)'s Anti-Neo-Confucianism. Han wrote a book na mod Myung-Suen-Lock(明善錄) which criticized Neo-Confucianism formed at times of Song dynasty in China and proposed a new doctrine i.e Anti-Neo-Confucianism. He asserted that The Sacred and Ordinary Men are all the same in nature, and that The Acatul Mind of Universe and The Actual Mind of Human also are all the same ultimately These two assertions cleary contrasted with pre-existing Neo-confucianism led Lee-jae-ma to successively organize Sasang constitutional theoy. This study is aimed to illuminate this point : How under the effects of Han's new doctrine Lee-jae-ma could find four general constitutions due to the functional variation of the four organs. At first, Lee indicated four organs as the very general basement providing human nature for all men including The Sacred. In consequence, he justified one of the Han's assertions that The Sacred and Ordinary Men are all the same in nature. Secondly, Lee indicated the Mind as the actual center which bring forth the individual spontaneity. As far as this individual spontaneity is rightly aimed, which means harmonize his own's with the actual process of the Universe, all men could be The Sacred. So he come to justify the other of Han's assertions that The Actual Mind of Universe and The Actual Mind of Human also are all the same ultimately. Therefore, it is clearly verified that the Lee-jae-ma's Sasang doctrine is the successive achievement origined from Han-suck-jie(韓錫地)'s Anti-Neo-Confucianism abundantly represented in his own book, Myung-Suen-Lock.

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Effects of ultraviolet radiation on the toxicity of water-accommodated fraction and chemically enhanced water-accommodated fraction of Hebei Spirit crude oil to the embryonic development of the Manila clam, Ruditapes philippinarum

  • Lee, Chang-Hoon;Sung, Chan-Gyoung;Kang, Sin-Kil;Moon, Seong-Dae;Lee, Ji-Hye;Lee, Jong-Hyeon
    • 한국패류학회지
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    • 제29권1호
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    • pp.23-32
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    • 2013
  • The purpose of this study is to evaluate the effects of oil dispersant and ultraviolet (UV) radiation on the toxicity of crude oil. The toxicity of water-accommodated fraction (WAF) and chemically enhanced water-accommodated fraction (CEWAF) of Hebei Spirit crude oil was investigated in the embryo of the Manila clam, Ruditapes philippinarum with- and without ultraviolet radiation. The WAF and CEWAF with- and without UV radiation affected significantly the embryonic development of R. philippinarum. The EC50s of WAF without UV, WAF with UV, CEWAF without UV, and CEWAF with UV were 2.82, 0.79, 1.60, and 0.45 g/L, respectively. CEWAF was 1.6 times more toxic than WAF. UV radiation increased crude oil toxicity to 3.6 times for both WAF and CEWAF. The oil dispersant and UV radiation did not affect the acute toxicity to the embryo but retarded the period of embryonic development up to 26%. R. philippinarum proved to be a sensitive species to reflect the toxic effects of oil spill combined with oil dispersant and UV radiation. It is suggested that the chemical analyses on the WAF and CEWAF is important for the identification and quantitative explanation of the phototoxic compounds in crude oil.

Development of the Rule-based Smart Tourism Chatbot using Neo4J graph database

  • Kim, Dong-Hyun;Im, Hyeon-Su;Hyeon, Jong-Heon;Jwa, Jeong-Woo
    • International Journal of Internet, Broadcasting and Communication
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    • 제13권2호
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    • pp.179-186
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    • 2021
  • We have been developed the smart tourism app and the Instagram and YouTube contents to provide personalized tourism information and travel product information to individual tourists. In this paper, we develop a rule-based smart tourism chatbot with the khaiii (Kakao Hangul Analyzer III) morphological analyzer and Neo4J graph database. In the proposed chatbot system, we use a morpheme analyzer, a proper noun dictionary including tourist destination names, and a general noun dictionary including containing frequently used words in tourist information search to understand the intention of the user's question. The tourism knowledge base built using the Neo4J graph database provides adequate answers to tourists' questions. In this paper, the nodes of Neo4J are Area based on tourist destination address, Contents with property of tourist information, and Service including service attribute data frequently used for search. A Neo4J query is created based on the result of analyzing the intention of a tourist's question with the property of nodes and relationships in Neo4J database. An answer to the question is made by searching in the tourism knowledge base. In this paper, we create the tourism knowledge base using more than 1300 Jeju tourism information used in the smart tourism app. We plan to develop a multilingual smart tour chatbot using the named entity recognition (NER), intention classification using conditional random field(CRF), and transfer learning using the pretrained language models.

네오 팝 아트의 특성을 적용한 아트 마스크 융합디자인 -무라카미 다카시의 작품을 중심으로- (Application of the Characteristics of Neo-Pop Art to the Convergence Design of the Art Mask -Based on the Works of Takashi Murakami-)

  • 박리라
    • 융합정보논문지
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    • 제9권6호
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    • pp.227-232
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    • 2019
  • 본 연구는 메이크업의 창의적 표현 영역으로서 주목받고 있는 아트 마스크에 네오 팝 아트를 접목하여 새로운 디자인 방향을 제안하는데 있다. 이론적 고찰을 통해 네오 팝의 특성을 분석한 후, 일본의 팝 아티스트인 무라카미 다카시의 작품을 모티브로 각 특성에 따라 총 4작품의 아트 마스크를 제작하였다. 연구 결과로는 첫째, 네오팝은 아트 마스크의 소재로 활용하기에 충분했다. 둘째, 네오 팝의 특성을 적용한 아트 마스크의 새로운 디자인을 제안할 수 있었다. 셋째, 미술과 메이크업의 융합을 통해 다양한 분야 간의 융합 가능성을 알 수 있었다. 향후 다양한 분야와의 융합을 통한 아트 마스크의 연구가 활발히 이루어지기를 바라며 본 연구가 아트 마스크 디자인 개발의 기초자료로 활용되기를 바란다.

자크뮈스 패션 컬렉션에 표현된 신-해체주의 특성 (Characteristics of Neo-deconstruction expressed in the Jacquemus fashion collection)

  • 유송주;이연희
    • 한국의상디자인학회지
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    • 제23권4호
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    • pp.39-56
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    • 2021
  • The purpose of this study was to observe the expressive characteristics of Neo-Deconstruction design, examine the expressive characteristics of Neo-Deconstruction design in the collections of Jacquemus, and analyze their internal meanings. For research, observations were made based on the concepts and expressive characteristics of Deconstruction through prior research and literary review, and analysis was conducted focusing on the expressive characteristics of Neo-Deconstruction. The scope of analysis included a total of 605 photographs collected from a total of 17 season collections of Jacquemus from the 2013 S/S to the 2021 S/S season. The results are as follows. First, the Neo-Deconstruction of Jacquemus expresses the youth culture using bright images such as diverse colors and patterns with 'positive playfulness' and pass on positive messages with deconstructive and playful forms, such as exaggeration and reduction and recombination and reconstitution. Second, with tendencies of 'symbolic receptivity', Jacquemus gained inspiration from his own life, memories, and hometown, and attempted to express the street women of places such as southern France, Paris, and Monaco in a number of collections. Also, he proposed designs that can be worn easily by anyone, regardless of gender, and as plus size models began to become more common respect was given to the tastes and preferences of diverse individuals without distinctions based on body type or sexuality. Third, 'geometric simplicity' was generally expressed by pursuing simple and practical fashion with the addition of details, such as geometric forms including stripes or asymmetrical expressions centering around everyday material that is used in clothing. Fourth, with "open communication," Jacquemus constructed his identity by addressing the various needs of consumers based on social network services and continuously sharing his creative ideas with the public. He is gaining popularity in a unique way by responding quickly to the changing atmosphere of society.

중풍 뇌 질환의 한 방향 협진에 관한 임상적 고찰 (Clinical Observation on East-West Integration Treatment in Stroke and Brain Disease)

  • 신애숙;이인환;김나희;김혜미;김민경;심소라;조승연;박성욱;박정미;배형섭;고창남
    • 대한중풍순환신경학회지
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    • 제11권1호
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    • pp.9-17
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    • 2010
  • Objectives : This study was aimed to evaluate the current status of East-West integrated treatment in stroke and brain disease and to discuss further plans. Methods : The medical records of patients who visited the stroke and brain disease center at Kyung Hee University, East-West Neo Medical Center from May 2006 to August 2010 were evaluated. The general characteristics of patients who underwent integrated treatment, trend in the number of cross referrals were initially evaluated. Later major disorders, the reasons of referrals and the number of visits in outpatients were analyzed. Results : 1. 3496 patients were referred from the eastern medical hospital to the western medical hospital and 2440 patients from the western medical hospital to the eastern medical hospital. The number of patients reached a peak alter the opening of the hospital and has decreased from then on. Referrals of female patients were more than those of male patients and patients over 50 years old were the most. 2. Admitted patients with stroke of chronic stage were most commonly referred from the eastern medical hospital to the western medical hospital and cerebral infarction was most common from the western medical hospital to the eastern medical hospital. Among the outpatients cerebral infarction topped from east to west, and stroke of chronic stage from west to east. 3. 36.6% of the patients from east to west received integrated treatment more than 3 times and 28.6% from west to east. Headache was the second most common reason to be referred from west to east and 36.7% of patients didn't continue to have either of the treatment and 30.3% received eastern treatment only, Conclusions: According to this study, chronic stroke management was successfully performed in the outpatient clinic in the form of East-West integration treatment. Further research on other diseases such as headache is recommended.

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한열변증에 따른 중풍 환자의 제반특성 비교 (The Comparison on the General Characteristics of Acute Stroke Patient between Heat pattern group and Cold pattern group)

  • 김민경;이인환;신애숙;김나희;김혜미;심소라;나병조;조승연;박성욱;정우상;문상관;박정미;고창남;조기호;김영석;배형섭
    • 대한중풍순환신경학회지
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    • 제11권1호
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    • pp.18-25
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    • 2010
  • Object : This study was conducted as part of the national project to standardize stroke diagnosis in Korean medicine. In this study, we aimed to evaluate the characteristics of acute stroke between heat pattern group and cold pattern group. Methods : We recruited stroke patients from 5 universities(Kyung-Hee University oriental medical center, Kyung-Hee University East-West Neo medical center, Kyungwon university lncheon oriental medical center, Kyungwon university Songpa oriental medical center and DongGuk university llsan oriental medical center) from April, 2007 until February, 2010. We diagnosed them and selected 463 heat pattern patients and 182 cold pattern patients. Results : We find that the risk factor of smoking, alcohol, diet(prefer to meat) are more associated with the heat pattern group. On the other hand, inflammation history in recent 3 months and diet(prefer to sea food) are more associated with the cold pattern group. RBC, Hg, Hct, TG, CK and Cl are more related to the heat pattern group. CPT, total cholesterol and HDL are more related to the cold pattern group. Tae-eum type takes high distribution of the heat pattern group, and So-eum type takes high distribution of the cold pattern group. Conclusions : This study provides evidence that the heat pattern group have more risk factor than the cold pattern group.

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Neoadjuvant therapy impact in early pancreatic cancer: "bioborderline" vs. "non-bioborderline"

  • Alvaro Gregorio Morales Taboada;Pablo Lozano Lominchar;Maria Fernandez Martinez;Pilar Garcia-Alfonso;Andres Munoz Martin;Jose Manuel Asencio
    • 한국간담췌외과학회지
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    • 제26권4호
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    • pp.363-374
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    • 2022
  • Backgrounds/Aims: To analyze the results of the neoadjuvant treatment of patients in our center with early pancreatic cancer. Methods: Eighty-four patients with early pancreatic cancer (I-II) were included, of which 59 were considered "bioborderline" (carbohydrate antigen [CA] 19-9 > 37 U/L), and 25 were considered "non-bioborderline" (CA19-9 < 37 U/L). The R0 resection rate, presence of negative nodes, survival, and recurrence rates were analyzed in two groups, the NEO group (neoadjuvant + surgery) and the nonNEO group (upfront surgery). Results: A 28.6% pathologic complete response was observed in the NEO group of the whole sample. The residual R0 was 85.7%, and nodes were negative in 78.6% of the patients in the NEO group of bioborderline patients. All non-bioborderline patients treated with neoadjuvant were R0, and no affected nodes were observed in any of them. The median overall survival (OS) in patients with elevated CA19-9 levels in the NEO group was 31.4 months vs. 13.1 months in the non-NEO (log-rank test p = 0.006), with a 62% relative reduction in the mortality rate (hazard ratio = 0.38, 95% confidence interval: 0.20-0.79; p= 0.008). The median OS in patients with normal CA19-9 levels in the NEO group was 65.9 months vs. 16.2 months in the non-NEO group, without statistically significant differences between the two but with a trend toward significance (log-rank test p = 0.08). Conclusions: A neoadjuvant strategy seemed to improve local control and the survival of patients with early pancreatic cancer, both those with elevated CA19-9 and normal marker levels.