• Title/Summary/Keyword: NCBP

Search Result 5, Processing Time 0.021 seconds

Nebulin C-terminus Interacts with NCBP51, a New Isoform of RING Finger Protein 125 (RNF125)

  • Kim, Ji-Hee;Kim, Hyun-Suk;Park, Eun-Ran;Choi, Jae-Kyoung;Lee, Yeong-Mi;Choi, Jun-Hyuk;Shin, Jung-Woog;Kim, Chong-Rak
    • Biomedical Science Letters
    • /
    • v.13 no.1
    • /
    • pp.1-10
    • /
    • 2007
  • Nebulin, a giant modular protein from muscle, is thought to act as molecular ruler in sarcomere assembly. In skeletal muscle, the C-terminal ${\sim}50 kDa$ region of nebulin extends into the Z-line lattice. The most recent studies implicated highlighting its extensive isoform diversity and exciting reports revealed its expression in cardiac and non-muscle tissues containing brain. Also these novel findings are indicating that nebulin is actually a multifunctional filament system, perhaps playing roles in signal transduction, contractile regulation, and myofibril force generation, as well as other not yet defined functions. However the binding protein of nebulin and function in brain is still unknown. A novel binding partner of nebulin C-terminal region was identified by screening a human brain cDNA library using yeast two-hybrid system. Nebulin C-terminus binding protein 51 (NCBP51) was contained a RING-finger domain and identified a new isoform of RING finger protein 125 (RNF125). The interaction was confirmed using the GST pull-down assay. NCBP51 belongs to a family of the RING finger proteins and its function remains to be identified in brain. The role of nebulin and NCBP51 will be studied by loss-of-function using siRNA technique in brain.

  • PDF

Adaptive Error Constrained Backpropagation Algorithm (적응 오류 제약 Backpropagation 알고리즘)

  • 최수용;고균병;홍대식
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.28 no.10C
    • /
    • pp.1007-1012
    • /
    • 2003
  • In order to accelerate the convergence speed of the conventional BP algorithm, constrained optimization techniques are applied to the BP algorithm. First, the noise-constrained least mean square algorithm and the zero noise-constrained LMS algorithm are applied (designated the NCBP and ZNCBP algorithms, respectively). These methods involve an important assumption: the filter or the receiver in the NCBP algorithm must know the noise variance. By means of extension and generalization of these algorithms, the authors derive an adaptive error-constrained BP algorithm, in which the error variance is estimated. This is achieved by modifying the error function of the conventional BP algorithm using Lagrangian multipliers. The convergence speeds of the proposed algorithms are 20 to 30 times faster than those of the conventional BP algorithm, and are faster than or almost the same as that achieved with a conventional linear adaptive filter using an LMS algorithm.

A study announcement about the game feeling decrease that is a sensitivity enemy in computer Based play (CBP) game transplant of a non-computer Based play (NCBP) game (비 컴퓨터플레이(NCBP)게임의 컴퓨터플레이(CBP)게임화에 따른 감성적 게임 체감(遞減)도 감소에 대한 연구 (인터페이스 디자인 및 게임도구디자인의 변화를 중심으로))

  • Kyung, Byung-Pyo
    • Journal of Korea Game Society
    • /
    • v.3 no.1
    • /
    • pp.18-23
    • /
    • 2003
  • Internal organs are in a game paduk[go] to play on a printing, and a poker, Korean playing cards having cards we. And I am with all kinds of electronic amusements to do a computer with a partner and baseball, soccer, golf, tennis, several hundred to enjoy in a stadium. Most games except a computer game are local, and a case to receive a courtship is in a game during this because I need time, personnel (the other party)? and a game tool. But a computer game is single, and a game is possible, and a number for the merit that can easily play a game by an offer of all tools is, and for this reason a lot of games to enjoy in a computer please be, and it has been transplanted. I do I in order to announce that interface of a game studied a problem and an improvement plan to have let there be a few I (to game interface) if a game is ported with a computer in this study by this.

  • PDF

A Study on the PCDDs/PCDFs Contents in the Flue Gas of Muncipal Solid Waste Incinerator(III) -Emission Concentration Varying the Combustion Temperature- (쓰레기소각로 배출가스의 PCDDs/PCDFs 함유량에 관한 연구(III) -소각로 연소 온도변화에 따른 보일러 후단에서의 배출 농도 변화-)

  • Shin, S.K.;Chung, Y.H.;Lee, J.I.
    • Analytical Science and Technology
    • /
    • v.12 no.6
    • /
    • pp.540-549
    • /
    • 1999
  • The combustion temperature was controlled between $880^{\circ}C$ to $1070^{\circ}C$ to find the relation the combustion temperature and emission amount of PCDDs/PCDFs in the Municipal solid waste incinerator. The emission amount of PCDDs/PCDFs decreased when the temperature increased in the rear of the boiler. The PCDDs/PCDFs concentration were detected $7.82ng-TEQ/Nm^3$ at $880^{\circ}C$, $6.97ng-TEQ/Nm^3$ at $970^{\circ}C$ and $6.13ng-TEQ/Nm^3$ at $1070^{\circ}C$. Also, The chlorophenols, chlorobenzenes, and PCB concentration decreased by increasing the temperature from $880^{\circ}C$ to at $1070^{\circ}C$, and the isomer of the prescsors had a tendency to emit the higbly cbiorinated compounds.

  • PDF

Emission Character of Dioxins and Precursors in the Control Devices of the MSWI (II) (도시쓰레기 소각로 방지시설 중 다이옥신류 및 전구물질의 배출특성(II))

  • Shin, S.K.;Chung, Y.H.;Lee, W.S.
    • Analytical Science and Technology
    • /
    • v.12 no.1
    • /
    • pp.68-74
    • /
    • 1999
  • The Concentrations of PCDDs/PCDFs and their precusors(chlorophenols, chlorobenzenes, PCB) were analyzed from the dioxin control device such as EP and SCR to know the emission patterns of these compounds and find the dioxin index compounds. The dioxin concentration increased 7 times in outlet part than inlet part of EP and the concentration of CBs, CPs and PCBs also were increased through this control device. These phenomia may be related to the operating temperature of Electroprecipitator(EP), which the operating temperature is near the $300^{\circ}C$, the method of the decreasing the operating temperature need to consider to prevent the formation of these compounds. In the selected catalytic reactor with wet scrubber(SCR+WS), these compounds were removed after passing the device over 90% for CPs, 30~40% for CBs and 60% for PCBs. But, the systematic study have to perform to reduce the formation of PCDDs/PCDFs and precusors.

  • PDF