• 한국진공학회:학술대회논문집
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• 한국진공학회 2007년도 제33회 하계학술대회 초록집
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• pp.120-120
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• 2007

• 한국진공학회:학술대회논문집
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• 한국진공학회 2006년도 제31회 학술논문발표회 초록집
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• pp.209-209
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• 2006

• 한국임상약학회지
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• 제21권1호
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• pp.6-13
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• 2011

Bolus intravenous injection of adenosine resulted the temporal decrease of systemic blood pressure and heart rate in the anesthetized rats. Adenosine also resulted the persistent decrease of contractility and heart rate in the isolated spontaneously beating rat right atria. Both of the above inhibition effets of adenosine were increased by the pretreatment of NBI (nitrobenzylthioinosine), whitch is an adenosine transport inhibitor, but decreased by the pretreatment of 8- phenyltheophy1line, which is an adenosine antagonist. In isolated thoracic aorta ring segment of normotensive rats, intact rings were relaxed by adenosine ($42.3{\pm}8.7%$) and ATP ($85.9{\pm}15.8%$) in the concentration of $10^{-4}M$, but rubbed rings were relaxed by adenosine ($35.2{\pm}1.9%$) and ATP ($11.3{\pm}9.0%$) in $10^{-4}M$. After pretreatment of L-NAME (N-Nitro-Larginine methyl ester), which is an NO inhibitor, adenosine-induced relaxation was not affected, but ATP-induced relax ation was significantly inhibited (P<0.01). Meanwhile, adenosine resulted almost same as vasorelaxation in isolated thoracic aorta of SHR comparing to those of normotensive rats. But, vasodilation responses of ATP in intact rings of SHR are significantly inhibited comparing to those of normotensive rats. Adenosine-induced relaxation is attenuated after 8-phenyltheophylline pretreatment, but increased after NBI pretreatment. However, ATP-induced relaxations are not affected by 8-phenyltheophylline or NBI pretreatment. These results suggested that the hypotensive effects of adenosine was due to the decrease of contractile force and heart rate through the A1 receptor and vasodilation are mediated by A2 receptor of the vascular smooth muscle. And, the heart protective and vasodilation effects of adenosine might suggest that it would be useful in the acute treatment of coronary artery disease.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2012년도 제43회 하계 정기 학술대회 초록집
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• pp.435-435
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• 2012

ITER를 비롯한 실증로나 상용로급 토카막에서는 중성빔 가열이나 전류구동을 위해 1MeV이상의 빔 에너지가 요구된다. 빔 출력이 가속전압의 5/2승에 비례함에도 불구하고 양이온 빔의 경우 에너지가 높아지면 빔의 중성화 효율이 급격히 감소하여 ITER NBI의 경우 양이온 빔의 중성화 효율은 0%에 가깝다. 한편 음이온 빔은 1MeV 이상의 에너지영역에서도 빔 에너지와 거의 무관하게 60% 정도의 중성화 효율을 갖는다. 따라서 ITER는 음이온 빔을 바탕으로 한 중성빔 가열장치(N-NBI)를 채택하고 있다. 우리나라의 핵융합연구가 핵융합 발전을 지향하는한 N-NBI에 대한 연구를 시작해야 하며 그 출발점으로 음이온원 개념설계를 시작하였다. 개념설계는 음이온원 개발과정을 통해 1) 음이온 생성원리 규명, 2) 음 이온원 핵심기술 확보, 3) 음이온 및 음이온 빔 관련 진단 등을 연구할 수 있는 축소규모의 proto-type 음이온원 개발을 목표로 하였다. 음이온원 개발은, 초기에는 KAERI NB test stand 및 KAERI 이온원의 플라즈마 버켓을 활용하기 위해 filament-arc type으로 시작하지만 어느정도 기반이 확립되면 플라즈마 버켓의 electron dump를 제거하고 그 자리에 RF driver를 장착하여 궁극적으로 RF 음이온원을 개발할 계획이다. 본 학회에 발표하는 포스터는 filament-arc type 음이온원에 대한 개념설계이다. 설계된 음이온원은 Tent-type 자장필터를 장착하며, 0.5A의 수소 음이온빔 인출을 목표로 하고 있다. 이를 위해 플라즈마 버켓, 세슘 공급시스템, bias plate, 플라즈마 그리드, electron deflection 자석이 설치된 인출 그리드, 접지 그리드 등에 대한 개념설계가 이루어 졌다. 이 외에도 음이온원 전원과 진단 시스템에 대해서도 논의하였다.

• Tuberculosis and Respiratory Diseases
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• 제68권1호
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• pp.16-21
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• 2010

Background: Lung cancer is usually diagnosed at an advanced stage, resulting in a poor prognosis. The detection of these lesions at an earlier stage would be a clear benefit to patients. However, it is extremely difficult to detect carcinomatous lesions in the bronchial mucosal sites during a routine bronchoscopy. Methods: This study employed a novel optical technique, known as narrowband imaging (NBI), which allows noninvasive visualization of the microvascular structure of an organ's surface using reflected light. Results: Narrow band imaging was performed on 10 patients who were radiologically suspicious or had a high risk of lung cancer. The median age of the patients was 57.5 years (range, 44~81 years), and 80% of the patients were male. All lesions showed a microvascular proliferation pattern (dotted, tortuous and abruptly ending vessel) on the magnified NBI. Two lesions were confirmed histologically to be adenocarcinoma and the remaining lesions were squamous cell carcinomas. Two lesions were confirmed histologically to be a carcinoma in situ. Conclusion: NBI is a promising and potentially powerful tool for identifying carcinomas at an earlier stage or a central lesion during a routine bronchoscopy examination.

• Asian Pacific Journal of Cancer Prevention
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• 제16권18호
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• pp.8487-8490
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• 2016

Background: Helicobacter pylori infection and premalignant gastric mucosa can be reliably identified using conventional narrow band imaging (C-NBI) gastroscopy. The aim of our study was to compare standard biopsy with site specific biopsy for diagnosis of H. pylori infection and premalignant gastric mucosa in daily clinical practice. Materials and Methods: Of a total of 500 patients who underwent gastroscopy for investigation of dyspeptic symptoms, 250 patients underwent site specific biopsy using C-NBI (Group 1) and 250 standard biopsy (Group 2). Sensitivity, specificity, and positive and negative predictive values were assessed. The efficacy of detecting H. pylori associated gastritis and premalignant gastric mucosa according to the updated Sydney classification was also compared. Results: In group 1 the sensitivity, specificity, positive and negative predictive values for predicting H. pylori positivity were 95.4%, 97.3%, 98.8% and 90.0% respectively, compared to 92.9%, 88.6%, 83.2% and 76.1% in group 2. Site specific biopsy was more effective than standard biopsy in terms of both H. pylori infection status and premalignant gastric mucosa detection (P<0.01). Conclusions: Site specific biopsy using C-NBI can improve detection of H. pylori infection and premalignant gastric mucosa in daily clinical practice.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2014년도 제46회 동계 정기학술대회 초록집
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• pp.241.1-241.1
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• 2014

The large-area high-power radio-frequency (RF) driven ion sources based on the negative hydrogen (deuterium) ion beam extraction are the major components of neutral beam injection (NBI) systems in future large-scale fusion devices such as an ITER and DEMO. Positive hydrogen (deuterium) RF ion sources were the major components of the second NBI system on ASDEX-U tokamak. A test large-area high-power RF ion source (LAHP-RaFIS) has been developed for steady-state operation at the Korea Atomic Energy Research Institute (KAERI) to extract the positive ions, which can be used for the NBI heating and current drive systems in the present fusion devices, and to extract the negative ions for negative ion-based plasma heating and for future fusion devices such as a Fusion Neutron Source and Korea-DEMO. The test RF ion source consists of a driver region, including a helical antenna and a discharge chamber, and an expansion region. RF power can be transferred at up to 10 kW with a fixed frequency of 2 MHz through an optimized RF matching system. An actively water-cooled Faraday shield is located inside the driver region of the ion source for the stable and steady-state operations of RF discharge. The characteristics and uniformities of the plasma parameter in the RF ion source were measured at the lowest area of the expansion bucket using two RF-compensated electrostatic probes along the direction of the short- and long-dimensions of the expansion region. The plasma parameters in the expansion region were characterized by the variation of loaded RF power (voltage) and filling gas pressure.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2004년도 추계학술발표회 발표논문집
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• pp.717-718
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• 2004

• 대한음성언어의학회:학술대회논문집
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• 대한음성언어학회 2017년도 제46차 춘계학술대회
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• pp.100-100
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• 2017

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2005년도 ICCAS
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• pp.1222-1227
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• 2005

In this paper, an efficient scheme of the adaptive notch filter is presented for rejecting the narrow bandwidth interferences(NBI) in GPS receiver. Designed is the lattice IIR double notch filter for more efficient suppression of the NBI with less computational complexity. The algorithm is of recursive prediction error form and uses a special constrained model of IIR with a minimal number of parameters. This paper chooses seven different jamming scenarios including one without jamming for evaluating the proposed filter algorithm. The simulation results to the jamming scenarios show that the proposed algorithm adjusts the double notch filter effectively for the given JSR, and provides better SNR than the conventional algorithms. Finally, it is shown that the advantages of the proposed filter algorithm can range as high as JSR 79dB in time domain processing. Also, the ADNF(adaptive double notch filter) guarantees that more than SNR 10dB of GPS receiver can be always maintained. In conclusion, there is enough evidence to believe that the proposed algorithm will perform quite well for removing interference signals.