• Title/Summary/Keyword: Myasthenia gravis

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A Case Study on Improvement of Myasthenia Gravis Using Ortho-Cellular Nutrition Therapy (OCNT) (세포교정영양요법(OCNT)를 이용한 중증근무력증 개선사례)

  • Eunsil Ji
    • CELLMED
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    • v.14 no.5
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    • pp.78.1-78.5
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    • 2024
  • Objective: Improvement of myasthenia gravis through Ortho-Cellular Nutrition Therapy (OCNT). Methods: A 52-year-old patient with myasthenia gravis was prescribed 21 different OCNT treatments, including Cyaplex. Results: Following the administration of OCNT, symptoms such as eyelid ptosis, masticatory dysfunction, diplopia, and fatigue showed improvement. Conclusion: OCNT can assist in alleviating and mitigating symptoms for patients suffering from thymoma and myasthenia gravis.

Clinical Study for Myasthenia Gravis (중근근무력증의 임상적 고찰)

  • 이정희
    • Journal of Chest Surgery
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    • v.26 no.3
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    • pp.219-223
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    • 1993
  • Myasthenia gravis is disorder of neuromuscular transmission that is characterized by weakness and fatigue of voluntary muscle. A clinical study of 18 cases of myasthenia gravis was performed at Chosun university college of medicine, from 1988 to 1992. Maximal thymectomy was performed in 7 cases and only medical treatment had been done in 11 cases.

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Castleman's Disease with Myasthenia Gravis

  • Lee, Sang-Kwon;Kim, Do-Hyung;Son, Bong-Soo
    • Journal of Chest Surgery
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    • v.45 no.3
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    • pp.199-201
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    • 2012
  • Castleman's disease is a rare disorder characterized by benign tumors that may develop in the lymph node tissue throughout the body. Castleman's disease associated with myasthenia gravis is an especially rare disease. Only less than 10 cases have been reported in the world literature. The cause of Castleman's disease is associated with immune mediated reaction, and myasthenia gravis also develops due to an antibody-mediated process. The cause of myasthenia gravis is the immune activity of Castleman's disease, which may be the promoter of the antibody-mediated process. We report here a case of Castleman's disease, which was incidentally found in a patient diagnosed with myasthenia gravis.

Surgical Management of Myasthenia Gravis (근무력증의 외과적 치료에 대한 임상적 고찰)

  • 김주현
    • Journal of Chest Surgery
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    • v.13 no.3
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    • pp.301-305
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    • 1980
  • Myasthenia gravis is a disorder that affects neuromuscular transmission in a way that is still poorly understood. some think that myasthenia gravis results from a reduction of available acetylcholine receptors in neuromuscular junctions, consequent to some form of autoimmune injury. Surgical interest in this disease was first aroused in 1939 when Blalock observed that some patients with thymic tumors and myasthenia gravis improved following thymectomy. This report represents two cases of myasthenia gravis. The 14-year-old girl was admitted to Korea Universtiy Hospital with chief complaintment of bilateral ptosis, diplopia, swallowing difficulty, and mastication difficulty, which were relieved by administration of edrophonium (Tensilon) chloride, given intravenously. Myasthenica gravis was confirmed and thymectomy was given. After thymectomy, symptoms were relieved but the administration of neostigmine was contijued to be needed till following 3 months. After that period, she was free from this symptoms without anticholinesterase drugs. Second case is 57 year old male who has the symptoms of diplopia, bilatreal ptosis, walking disturbance, and speech difficulty. He had thymectomy too but in thymic tissue, malignant thymoma was included. He has subjective improvement only, with no major reduction of medication requirements after thymectomy.

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A Case of Myasthenia Gravis (중증 근무력증 1례)

  • 진성민;이성채;송윤경;이한보
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.9 no.2
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    • pp.164-167
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    • 1998
  • Myasthenia gravis is a neuromuscular disorder that affects striated muscles especially those innervated by the cranial nerves. Most patients present with symptoms relating to the head and neck and thus may be seen first by the otolaryngologist. Recently we had experienced a case of myasthenia gravis with the complaints of hypernasality and voice fatigue in a 49 year old male. In this case, all symptoms were improved markedly with administration of anticholinesterase.

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Role of Thymectomy for the Management of Myasthenia Gravis (근무력증의 외과적 치료)

  • 이동협
    • Journal of Chest Surgery
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    • v.18 no.4
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    • pp.859-866
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    • 1985
  • The characteristic features of myasthenia gravis, which are weakness of voluntary muscle and easy fatigability, result from defective neuromuscular transmission caused by an autoimmune response to acetylcholine receptor. Recently, we performed two cases of thymectomy for the treatment of myasthenia gravis, one was 50 year old man who had malignant thymoma and the other was 19 year old girl who had benign thymic hyperplasia. The former had long duration of symptoms, and showed poor postoperative result. The latter had short duration of symptoms, and showed complete remission. Herewith, we suggest that early thymectomy can give the clinical assets for myasthenia gravis. So we report these two experiences with review of literatures.

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Multiple Thymoma with Myasthenia Gravis

  • Seo, Dong Hyun;Cho, Sukki
    • Journal of Chest Surgery
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    • v.50 no.1
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    • pp.68-70
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    • 2017
  • The actual incidence of multiple thymoma is unknown and rarely reported because it remains controversial whether the cases represent a disease of multicentric origin or a disease resulting from intrathymic metastasis. In this case, a patient underwent total thymectomy for multiple thymoma with myasthenia gravis via bilateral video-assisted thoracic surgery. A well-encapsulated multinodular cystic mass, measuring $57mm{\times}50mm{\times}22mm$ in the right lobe of the thymus, and a well-encapsulated mass, measuring $32mm{\times}15mm{\times}14mm$ in the left lobe, were found. Both tumors were type B2 thymoma. Few cases of multiple thymoma with myasthenia gravis have ever been reported in the literature. We report a case of synchronous multiple thymoma associated with myasthenia gravis.

Anesthetic Experiences of Myasthenia Gravis: Report of two cases (중증근무력증 환자의 마취 2례 보고)

  • Park, Dae-Pal;Lee, Kyung-Chul
    • Journal of Yeungnam Medical Science
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    • v.2 no.1
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    • pp.287-292
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    • 1985
  • Myasthenia gravis is usually defined as a state of abnormal fatigability. The cause of myasthenia gravis is not known. Several disorders tend to occur more frequently in patients with myasthenia gravis, such as hyperthyroidism or other thyroidal disorder. Anesthetic experience with thymectomies for two patients with myasthenia gravis has been reported. Both of them tolerated the surgical procedures under endoteracheal Nitrous oxide-Oxygen-Halothane anesthesia well. Diagnosis and clinical features including choice of preanesthetic medication, anesthetic agents, techniques and of neuromuscular blocking agents for myasthenic patients have been discussed. Paramount importance of rigid attention to ventilation, the maintenance of a patent airway and the removal of secretions whenever necessary for the patient safety throughout operative and postoperative period has been stressed.

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A Case Study on the Alleviation of Symptom of a Myasthenia Gravis Patient after Korean Medicine Treatment (중증근무력증이 한의학적 치료로 개선된 임상 1례)

  • Bae, Young-chun;Park, Soo-jung
    • The Journal of Internal Korean Medicine
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    • v.40 no.1
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    • pp.136-144
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    • 2019
  • Objective: The purpose of this study was to report on the alleviation of symptoms of a myasthenia gravis (MG) patient after Korean medicine treatment. Methods: A 39 year-old male patient who suffered from MG was examined. The patient was treated with herbal medicine, acupuncture, and pharmacopuncture. The Myasthenia Gravis Composite (MGC) scale and Myasthenia Gravis Activities of Daily Living (MG-ADL) profile were used to assess the change of MG symptoms after Korean medicine treatment. Results: The MGC and MG-ADL scores indicated significant improvement after 14 days of treatment. In addition, the degrees of fatigue, dyspepsia, vomiting, sweating, and dizziness were decreased. Conclusion: This study may suggest that Korean medicine treatment could be effective in treating the symptoms of MG.

Laryngeal Paralysis in a Cat with Malignant Thymoma

  • Hyeona Bae;Il-Hwa Hong;Dong-In Jung;DoHyeon Yu
    • Journal of Veterinary Clinics
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    • v.40 no.1
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    • pp.68-72
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    • 2023
  • A 10-year-old castrated male Domestic Shorthair cat visited a veterinary medical teaching hospital for emergency dyspnea. The cat was hypoxic and hypotensive, and stridorous respiration was remarkable. Visual inspection confirmed laryngeal paralysis and a lack of mobility of the left larynx. Megaesophagus, aspiration pneumonia, cranial mediastinal mass, and positive Tensilon test results using neostigmine were observed, indicating acquired myasthenia gravis secondary to thymic neoplasia. After 10 minutes of neostigmine 0.02 mg/kg IV administration, laryngeal paralysis and dyspnea resolved. Histopathlogical examination for the cranial mediastinal mass after surgical resection confirmed malignant thymoma. Here, we report a case of acquired myasthenia gravis in a cat with a malignant thymoma that presented with life-threatening dyspnea due to laryngeal paralysis. Feline laryngeal paralysis is uncommon, and myasthenia gravis, a cause of laryngeal paralysis in cats, has not yet been reported. Myasthenia gravis should be considered in cats with laryngeal paralysis.