• Parasites, Hosts and Diseases
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• v.53 no.4
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• pp.431-438
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• 2015

In Trichinella spiralis infection, type 2 helper T (Th2) cell-related and regulatory T ($T_{reg}$) cell-related immune responses are the most important immune events. In order to clarify which Toll-like receptors (TLRs) are closely associated with these responses, we analyzed the expression of mouse TLR genes in the small intestine and muscle tissue during T. spiralis infection. In addition, the expression of several chemokine- and cytokine-encoding genes, which are related to Th2 and $T_{reg}$ cell mediated immune responses, were analyzed in mouse embryonic fibroblasts (MEFs) isolated from myeloid differentiation factor 88 (MyD88)/TIR-associated proteins (TIRAP) and Toll receptor-associated activator of interferons (TRIF) adapter protein deficient and wild type (WT) mice. The results showed significantly increased TLR4 and TLR9 gene expression in the small intestine after 2 weeks of T. spiralis infection. In the muscle, TLR1, TLR2, TLR5, and TLR9 gene expression significantly increased after 4 weeks of infection. Only the expression of the TLR4 and TLR9 genes was significantly elevated in WT MEF cells after treatment with excretory-secretory (ES) proteins. Gene expression for Th2 chemokine genes were highly enhanced by ES proteins in WT MEF cells, while this elevation was slightly reduced in MyD88/$TIRAP^{-/-}$ MEF cells, and quite substantially decreased in $TRIF^{-/-}$ MEF cells. In contrast, IL-10 and $TGF-{\beta}$ expression levels were not elevated in MyD88/$TIRAP^{-/-}$ MEF cells. In conclusion, we suggest that TLR4 and TLR9 might be closely linked to Th2 cell and $T_{reg}$ cell mediated immune responses, although additional data are needed to convincingly prove this observation.

• Journal of Korean Home Economics Education Association
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• v.5 no.1
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• pp.61-85
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• 1993

Because of the specificity of subjects belong to middle school curriculum of Home Economics Education of function training is very important. but it pointed out that the existing standards are out-dated, and because of it , it incongruent to our realities. Therefore, whenever the curriculum o education and the national textbook are reorgrnized periodically, the reform of standards of educational materials & facilities must be followed by it. But in my opinion, in korean middle school, especially in Home Economics Education, educational facilities are not reformed at a proper time. Therefore to enhance the qualities of experimentation/practice of Home Economics Education, in the first place, the preparation for the given conditions of standards of educational materials & facilities are needed. But the educational facilities of Home Economics Education have many problem not only in the qualitative aspect but also in the quantitative aspect. And in addition to it, lost of educational facilities which cannot match contents of national textbook of Home Economics Education are exist. Therefore this thesis aims at examining comprehensively the problem of experimentation /practice of experimental materials & facilities of Home Economics Education connect with contents of Home Economics Education, holding several problems of experimentation/practice of Home Economics Education in middle school, grouping ; the principles and ways concerning the innovation experimental materials & facilities of Home Economics Education by which many teachers and students make sure of more efficient teaching/studying, and obtaining basic data which guarantee the ability of innovation concerning problems of the education of experimentation/practice of Home Economics Education. Method are : 1)grasp our educational realities with my original(question). 2)Integrate/analyse results of 1) 3)check the frequency, percentage with methods of X$^2$-test, T-test, and ‘One-way Analysis of Variances’. 4)suggest my own alternative proposal.

• Korean Journal of Oriental Medicine
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• v.16 no.1
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• pp.111-118
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• 2010

Objectives : We identified the applicability of Sasang constitution for the enhancement of job satisfaction, job performance and organizational commitment in office workers. Methods : We conducted a survey using a Sasang constitution questionnaire to identify the Sasang types, and several questionnaires to identify organizational commitment, job performance and job satisfaction of 205 office workers who live in D city. Data were analyzed with ANOVA test. Results 1. In organizational commitment, Sasang constitution showed a significant correlation in the question of "I feel that I am not a real member of this company" and the order of score was Soeumin, Taeeumin, and Soyangin. 2. In job performance, Sasang constitution showed significant correlations in the questions of "I always achieve my goals" and "I am recognized as a person who has a good job performance" and the order of score was Soeumin, Taeeumin, and Soyangin. 3. In job satisfaction, Sasang constitution showed a significant correlation in the questions of "I am forced to go to the office" and the order of score was Soeumin, Soyangin, and Taeeumin. Sasang constitution also showed significant correlations in the questions of "I am usually passionated in my work", and "I was disappointed when I got at my job" and the order of score was Soeumin, Taeeumin, and Soyangin. Conclusions : Sasang constitution. had significant correlation in organizational commitment, job performance and job satisfaction in office workers.

• Food Science of Animal Resources
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• v.42 no.1
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• pp.84-97
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• 2022

We evaluated the anti-biofilm formation and anti-inflammatory activity of Hovenia monofloral honey (HMH) against Enterococcus faecalis. Co-culture of HMH with E. faecalis attenuated the biofilm formation of E. faecalis on a polystyrene surface. In addition, HMH effectively eradicated the established E. faecalis biofilm. HMH significantly attenuated E. faecalis growth but did not affect the production of extracellular polymeric substances on E. faecalis, indicating that reduction of E. faecalis biofilm is a result of HMH-mediated killing of E. faecalis. Furthermore, we found that HMH can effectively attenuate E. faecalis-induced expression of a proinflammatory interleukin-8 (IL- 8) in HT-29 cells. Interestingly, treatment of HMH significantly attenuated the E. faecalis-mediated expression of Toll-like receptor-2 (TLR-2) and its adaptor molecules, myeloid differentiation primary response 88 (MyD88), in HT-29 cells. In addition, E. faecalis-induced mitogen-activated protein kinases (MAPKs) phosphorylation was significantly attenuated by HMH administration. Furthermore, HMH-mediated antiinflammatory efficacy (0.2 mg/mL of HMHs) had an equal extent of inhibitory efficacy as 5 μM of MyD88 inhibitor to attenuate E. faecalis-mediated IL-8 expression in HT-29 cells. These results suggest that HMH could effectively inhibit E. faecalis-mediated gastrointestinal inflammation through regulating the TLR-2/MyD88/MAPKs signaling pathways. Collectively, our data suggest that HMH could be developed as a potential natural agent to control E. faecalis-mediated biofilm formation and inflammation.

• Journal of Korea Multimedia Society
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• v.21 no.8
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• pp.934-941
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• 2018

There are some limits on cost and efficiency for large amount of data in RDBMS, and NoSQL is starting to gain popularity. In medical institutions, data forms are different between organizations, and that makes difficulty for interoperability between organizations. In this paper we focused on performance issues between RDMBS and NoSQL in medical documents. We had built two different environment and had experiment comparative analysis of NoSQL with RDBMS based on medical data. We used medical HL7 FHIR as a medical data standard. Also YCSB benchmark tool was used for performance comparison. Experiments shows that NoSQL has better performance in large amounts of medical data processing systems that have over 10,000~100,000 records.

• International journal of advanced smart convergence
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• v.11 no.1
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• pp.127-133
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• 2022

This study aims to find out the associative relationship between dementia and comorbidities. To conduct this study, we used KNHDIS(Korea National Hospital Discharge In-depth Injury Survey) data from 2009 to 2018 provided by the KDCA(Korean Disease Control and Prevention Agency) annually. We used MySQL for data preprocessing and R for data analysis. As a result of applying the Apriori algorithm criteria of support(≥0.01), confidence(≥ 0.6), and lift(>1), seventeen rules related to dementia were discovered. The diseases associated with dementia were diabetes mellitus, hypertension, disorders of lipoprotein metabolism, glomerular disorders in diabetes mellitus, renal diseases, cardiovascular disease, cerebrovascular disease, and other urinary system disorders. This study can be utilized as primary data for the care of patients with dementia and provides implications for improving effective dementia prevention policies.

• Informatization Policy
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• v.28 no.3
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• pp.49-72
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• 2021

This study analyzes the major content, significances, and future outlook of Three Data Acts amendment enacted in August 2020 in South Korea, with the focus on their impact on the financial and data industries. It seems that the revision of the Credit Information Act will enable the specification of a business which had previously only been regulated as the business of credit inquiry, and also enable the domestic data industry to activate the MyData industry, data trading and platforms, and specify data pseudonymization and trading procedures. For the rational and efficient implementation of the amendments to the Three Data Acts, the Personal Information Protection Committee must be as transparent and lawful in its activities as possible, and fairness must be guaranteed. Even in the utilization of personal information, the development or complementation of the related data processing technologies is essential, and clear data processing methods and areas must be regulated. Furthermore, the amendments must be supported with guarantees and the systematization of a fair competitive system in the data market, stricter regulations on penalties for illegal acts related to data, establishment and strengthening of the related security systems, and reinforcement of the system of cooperation for data transfer.

• Journal of the Korea Society of Computer and Information
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• v.13 no.6
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• pp.217-224
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• 2008

EThis paper is study regarding banking institution and DoS attack regarding government organization which occurred in 2008. We used a tool aggressive actual DoS You install the N-IDS which used Snort in networks in order to detect a DoS attack. Storages of Winpcap and a packet to detect a packet and MySQL, HSC, to analyze. We install NET Framework etc. E-Watch etc. analyzes Packet regarding a DoS attack of a hacker and TCP, UDP etc. information, Port, MAC and IP information etc. through packet analysis tools. There is a meaning you analyze data regarding the cyber DoS, DDoS attack that is dysfunction of Ubiquitous Information Society, and it generates forensics data regarding an invader and back-tracking analysis data, and to ensure safe Internet information system through this paper study.

• Journal of The Korean Society of Integrative Medicine
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• v.10 no.1
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• pp.39-48
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• 2022

Purpose : This study aimed to determine the experiences of the disaster response team 9 participants who participated in the disaster after the fire incident occurred in Jecheon Sports Center and their meaning and essence. Methods : Nine disaster response teams were the subjects of the study, and Individual in-depth interviews were conducted. Data were collected online between January 6 and April 30, 2021, from the software Zoom^TM. This study was conducted as a qualitative study by applying Giorgi's phenomenological experiential research method, which has an advantage in revealing the essential structure and meaning of experience. Results : Three major themes were derived from the study results: the stimulus through unfamiliar experiences, the grievances due to work environment and regional characteristics, and dullness resulting from hiding and enduring. The following 17 sub-themes were identified: learning through unfamiliar experiences, frustration due to unexpected circumstances, shock from unfamiliar experiences, doing my best in the present, confidence due to increased experience, disunified system, intervention of various interests, the atmosphere that puts responsibility on others, inactive help, unforgettable regional characteristics, working without time to settle, tolerating it in my own way, memories left in the unconsciousness, sudden suffering from memories that come to mind, movement in anxiety and tension, dullness, work with colleagues in the same situation. Conclusion : This study is meaningful in that it attempted to provide basic data in preparing a long-term strategy for effective policy direction and institutional protection based on the systematic mental health management of the disaster response team. Additionally, this study's results can be used as primary data for future research among Disaster Response Team.

• Journal of the Korea Computer Graphics Society
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• v.30 no.3
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• pp.159-169
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• 2024

This paper proposes a new real-time fire monitoring and evacuation navigation system by integrating Augmented Reality (AR) technology with Internet of Things (IoT) technology. The proposed system collects temperature data through IoT temperature measurement devices installed in buildings and automatically transmits it to a MySQL cloud database via an IoT platform, enabling real-time and accurate data monitoring. Subsequently, the real-time IoT data is visualized on a 3D building model generated through Building Information Modeling (BIM), and the model is represented in the real world using AR technology, allowing intuitive identification of the fire origin. Furthermore, by utilizing Vuforia engine's Device Tracking and Area Targets features, the system tracks the user's real-time location and employs an enhanced A^* algorithm to find the optimal evacuation route among multiple exits. The paper evaluates the proposed system's practicality and demonstrates its effectiveness in rapid and safe evacuation through user experiments based on various virtual fire scenarios.