• 한국전문물리치료학회지
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• 제22권2호
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• pp.70-80
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• 2015

The spinal cord is highly complex, consisting of a specialized neural network that comprised both neuronal and non-neuronal cells. Any kind of injury and/or insult to the spinal cord leads to a series of damaging events resulting in motor and/or sensory deficits below the level of injury. As a result, muscle paralysis (or paresis) leading to muscle atrophy or shrinking of the muscle along with changes in muscle fiber type, and contractile properties have been observed. Traditionally, histology had been used as a gold standard to characterize spinal cord injury (SCI)-induced adaptation in spinal cord and skeletal muscle. However, histology measurements is invasive and cannot be used for longitudinal analysis. Therefore, the use of conventional magnetic resonance imaging (MRI) is promoted to be used as an alternative non-invasive method, which allows the repeated measurements over time and secures the safety against radiation by using radiofrequency pulse. Currently, many of pathological changes and adaptations occurring after SCI can be measured by MRI methods, specifically 3-dimensional MRI with the advanced diffusion tensor imaging technique. Both techniques have shown to be sensitive in measuring morphological and structural changes in skeletal muscle and the spinal cord.

• The Korean Journal of Physiology and Pharmacology
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• 제26권3호
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• pp.207-218
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• 2022

Aging in mammals, including humans, is accompanied by loss of bone and muscular function and mass, characterized by osteoporosis and sarcopenia. Although resistance exercise training (RET) is considered an effective intervention, its effect is blunted in some elderly individuals. Fibroblast growth factor (FGF) and its receptor, FGFR, can modulate bone and muscle quality during aging and physical performance. To elucidate this possibility, the FGFR inhibitor NVP-BGJ398 was administrated to C57BL/6n mice for 8 weeks with or without RET. Treatment with NVPBGJ398 decreased grip strength, muscular endurance, running capacity and bone quality in the mice. FGFR inhibition elevated bone resorption and relevant gene expression, indicating altered bone formation and resorption. RET attenuated tibial bone resorption, accompanied by changes in the expression of relevant genes. However, RET did not overcome the detrimental effect of NVP-BGJ398 on muscular function. Taken together, these findings provide evidence that FGFR signaling may have a potential role in the maintenance of physical performance and quality of bone and muscles.

• 대한지역사회영양학회지
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• 제11권1호
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• pp.143-151
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• 2006

Regular exercise training improves body composition, blood lipid profiles and exercise adaptation. This study was conducted to investigate the effect of exercise training at different times of day on body composition, blood lipids, stress hormones and nutrient intakes. Twenty four male graduate students carried out this experiment. The subjects were divided into three groups; morning exercise group, evening exercise group and control group. Two exercise groups performed running and muscular resistance training at mid intensity for 12 week periods. Body composition, blood lipid profiles, blood cortisol, ACTH and nutrient intakes were analyzed prior to, midway and after training. There were significant differences about interaction between different exercise times and training periods in plasma TG and HDL-C of the evening exercise training (p < 0.05). Also the evening exercise group was showed the decreasing of TC after training (p < 0.05). No significant differences about interaction between different exercise times and training periods were shown in body composition, stress hormones and nutrient intakes in the three groups. But evening exercise training decreased body fat ($\%$) and blood ACTH (p < 0.05). Also the increasing of carbohydrate intakes was shown by the evening exercise training (p < 0.05). In contrast, morning exercise group indicated a decrease of body fat ($\%$) after 6 week training (p < 0.05), but this effect was not maintained after 12 weeks of training. These results suggested that regular evening exercise is more effect than morning exercise from the viewpoint of improving body composition, blood lipids, nutrient intakes and exercise adaptation.

• 재활치료과학
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• 제10권1호
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• pp.37-52
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• 2021

서론 : 구강 운동 기능은 태아기에서 유년기 발달로 이어지는 감각 탐색, 음식 섭취, 의사소통 표현의 기초가 되는 기능이다. 구강 운동 기능에 문제가 발행하면, 구강 내 음식 처리 어려움, 삼킴 및 섭식기능 저하, 의사소통 기능 감소, 구강 위생 능력 저하 등이 나타난다. 이러한 증상 치료를 위한 구강운동 치료는 구강 내 감각 정상화, 자세 조절, 구강 움직임 증진, 구강 운동 기능 향상을 목표로 제공되는 치료법이다. 본론 : 구강운동촉진기술(OMFT)은 1) 구강 및 안면 근육계의 해부생리학적 이해; 2) 감각·적응·행동·인지의 통합적 접근; 3) 도수적 접근을 통한 감각 및 운동 자극; 4) 운동 조절과 운동 학습 이론에 기초한 구강운동의 4가지 주요 특징을 바탕으로 전반적이고 통합적인 구강 기능 증진을 목적으로 개발되었다. OMFT는 근거 중심의 새로운 치료 프로토콜로써 아동 및 성인, 신경계 및 근골격계의 구강 기능에 문제를 보이는 모든 이들에게 적용이 가능한 치료 기법이다. 결론 : 본 논문은 OMFT의 개발에 따른 이론적 배경 및 OMFT의 실제적 적용에 따른 기초 요소를 소개하는 것이 목표로, 본 논문을 통해 임상 전문가들이 정확한 이론적 배경과 치료법을 바탕으로 대상자에 맞는 전문적인 치료 제공에 도움이 되기를 바란다.

• The Journal of Korean Physical Therapy
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• 제15권3호
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• pp.16-44
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• 2003

Skeletal muscle regeneration is a vital process for various muscle myopathies and muscular adaptation to physiological overload. Angiogenesis is the key event in the process of muscle regeneration, and vascular endothelial growth factor(VEGF) plays an important role in it. The purpose of this study was to evaluate the effect of GaAlAs(830nm) laser and immunoreactivity of VEGF on angiogenesis after muscle contusion injury. Muscle contusion injury was induced in the triceps surae muscle by dropping a metal bead(31.4g). GaAlAs laser irradiation(power 20 mW, frequency 2000 Hz, treatment time 15 min) was applied directly to the skin of injured muscle daily for seven days. The experimental group I was irradiated immediately by laser after injury, whereas the experimental group II was irradiated after 1 day of injury. The control group was non-irradiated. The results of this study were as follows. 1. In morphological observation, there were no significant changes in experimental and control groups for 7 days. At 3 days, however, the splited muscle fibers were observed in experimental groups, and the muscle atrophy and granular tissue viewed at 7 days in control group. 2. The VEGF was expressed in muscle fiber that located in the interspace between gastrocnemius and soleus muscles. As the time coursed, the immunoreactivity of VEGF also seemed to be strong in the individual muscle fibers. 3. The experimental group I & II showed higher immunoreactivity of VEGF than control group(p<0.05). Then, the experimental group I showed higher than group II especially(p<0.05). These data suggest GaAlAs semiconduct diode laser irradiation(830nm) enhanced angiogenesis in the skeletal muscle induced contusion injury, and immediate laser irradiation after injury promoted the angiogenesis greatly than after 1 day of injury.

• Journal of Yeungnam Medical Science
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• 제5권1호
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• pp.61-67
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• 1988

1. 저자들은 1986년 11월부터 1988년 2월까지 경골간부 골절 8례를 나사못 맞물림법을 이용한 골수강내 금속정을 사용하여 치료하였다. 2. 술 후 방사선 소견상 골유합 기간은 평균 약 15주였다. 3. 환자의 입원기간은 평균 5.5주로서 비교적 짧은 입원기간을 보여주었으며 아울러 사회복귀 및 적응이 빨랐다. 4. 술 후 조기운동이 가능하였고 평균 4.3주 경과 후 목발보행을 시작하였다. 5. 술 후 관절강직, 근위축등의 합병증은 거의 없었다. Hamza등에 의한 술후 평가방법에 따르면 Excellent 7례, Good 1례로 결과는 만족스러웠다.

• 대한물리치료과학회지
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• 제7권2호
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• pp.663-682
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• 2000

The purpose of this study was to identify the superior exercise on the reduction of low back pain, between the Mckenzie exercise and the williams exercise. 24 chronic low back pain patients were randomly divided into 3 groups (Mckenzie exercise group = 8, williams exercise group = 8, control group = 8). Each group examined using the Borg scale in a reduction of low back pain, the EMG amplitude in a stationary sit-up position and in a stationary 1000 back extension position. The Results are as follow. 1. After the training period, the Mckenzie exercise group and the williams exercise group revealed reduction of low back pain, but the control group does not revealed it. 2. After the training period, there were no significant differences on the reduction of low back pain between the Mckenzie exercise group and the williams exercise group. 3. After the training period, no groups decreased on the abdominal muscle EMG amplitude. 4. After the training period, all groups revealed no significant differences on the abdominal muscle EMG amplitude. 5. After the training period, all groups decreased on the low back muscle EMG amplitude. 6. After the training period, all groups revealed no significant differences on the low back muscle EMG amplitude. Overall, the study suggested that the Mckenzie exercise and the williams exercise achieve the same effect on the reduction of low back pain, and the fact seems to be influenced by other factors without muscular adaptation.

• 대한정형도수물리치료학회지
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• 제12권1호
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• pp.57-67
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• 2006

Musculoskeletal neck dysfunction syndromes are common in outpatient musculoskeletal pain practice. The underlying musculoskeletal and neurologic causes of pain are variable. In the management of these patients, it is important to accurately identify and treat these pain generators to optimize patient outcome. It is the purpose of this review to discuss three main categories of functional anatomy, the role of superficial/deep muscular system and the scientific evidence for optimal physical therapy intervention for cervical dysfunction. Specifically there is evidence of lowered microcirculation in the upper trapezius muscle, morphological signs of disturbed mitochondrial function which appears to be limited to type I fibers and an increased cross-sectional area of type I muscle fibers despite a lower capillary to fiber area ratio. In acute neck pain syndrome, changes in muscle activity of painful muscles may result from segmental and supraspinal inhibitory effects. Muscle activation is closely related to the control of joint movements and postures and it is difficult to separate the influence of the two components. Both the altered muscle recruitment patterns and altered kinematics appear to be a poor adaptation for pain of the head - neck region, as they are likely to result in increased compressive loading in the cervical spine, affecting muscles, articular structures such as zygapophyseal joints, connective tissues and neural tissues which are all peripheral generators of referred pain. The rectus capitus posterior minor muscle shows that it is one of the most important muscles of the suboccipital region. In this article, i reviewed the anatomy, neurophysiology, function and dysfunction as well as the treatment of cervical dysfunction.

• 대한치과보철학회지
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• 제60권1호
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• pp.91-99
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• 2022

심한 치아 마모는 치료되지 않고 방치될 경우에 치아 구조물의 상실, 치수 합병증, 착색, 기능과 심미의 상실과 같은 여러 합병증 등을 야기한다. 본 증례의 환자는 전치부에서 특히 심한 치아마모를 보이며 수복공간 부족을 보이는 경우로 수직고경 거상을 동반한 전악 고정성 보철물로 수복을 하였다. 진단납형을 토대로 수직거상량을 결정하고 가철성 교합안정장치를 6주간 장착하여 적응도를 평가하였다. 이후 고정성 임시보철물을 수복함으로써 3달간 근신경계의 조화, 심미, 측두하악관절 등에 대하여 재평가하였다. 위와 같은 치료과정을 통해서 단일구조 지르코니아를 이용한 전악 고정성 보철물로 최종수복을 완료하였고 기능적, 심미적으로 안정적인 결과를 얻었기에 보고하는 바이다.

• 턱관절균형의학회지
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• 제12권1호
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• pp.1-6
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• 2022

Objectives: For the deviation phenomenon occurring during the treatment process in temporo-mandibular balancing medicine (TBM), hypotheses were established regarding the cause and mechanism of formation from the perspective of neuro-science and material mechanics, and a verification method was proposed. Methods: The deviation phenomenon was theoretically analyzed based on the structure theories of material mechanics of the joint and the neurological pain mechanism. Results: Deviation occurs due to temporary yield by the accumulation of heterogeneous stress in the temporo-mandibular joint and the affected joint. Because the joint structures are corresponding with material mechanics showing compressive and tensile properties. The size of the deviation is expressed in terms of strain. The occlusal surface of the teeth is level with the axial joint. Since the magnitude of the deviation has a proportional relationship with the degree of abnormality of the temporo-mandibular joint, the magnitude of the deviation calculated by the balance measurement can be replaced by the strain. The major variables involved in the occurrence of deviations are the strength of joint structures and neurological conditions. Therefore plastic deformation and adaptation occur as a long-term depression of neural circuits is strengthened in different ways at different locations each time in various clinical situations. This is the reason why the sequence of the restoration process while correcting deviations is following reverse order of the accumulation in many layers in the muscular nervous system. Conclusions: From the above results, it can be inferred that the occurrence and correction of the deviations are corresponding with the plastic deformation and neuro-plasticity.