• Integrative Medicine Research
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• 제2권4호
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• pp.131-138
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• 2013

The skeletal muscle in our body is a major site for bioenergetics and metabolism during exercise. Carbohydrates and fats are the primary nutrients that provide the necessary energy required to maintain cellular activities during exercise. The metabolic responses to exercise in glucose and lipid regulation depend on the intensity and duration of exercise. Because of the increasing prevalence of obesity, recent studies have focused on the cellular and molecular mechanisms of obesity-induced insulin resistance in skeletal muscle. Accumulation of intramyocellular lipid may lead to insulin resistance in skeletal muscle. In addition, lipid intermediates (e.g., fatty acyl-coenzyme A, diacylglycerol, and ceramide) impair insulin signaling in skeletal muscle. Recently, emerging evidence linking obesity-induced insulin resistance to excessive lipid oxidation, mitochondrial overload, and mitochondrial oxidative stress have been provided with mitochondrial function. This review will provide a brief comprehensive summary on exercise and skeletal muscle metabolism, and discuss the potential mechanisms of obesity-induced insulin resistance in skeletal muscle.

• 한국전문물리치료학회지
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• 제18권4호
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• pp.26-33
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• 2011

The aim of this study was to investigate the effects of respiratory muscle training (RMT) with abdominal drawing-in maneuver (ADIM) on pulmonary function. Twenty-two subjects with restrictive breathing participated in this study. All the subjects were randomly assigned to three groups (7 subjects in RMT group, 7 subjects in RMT with ADIM group, 8 subjects in control group). The first group performed the RMT by using incentive respiratory spirometer (IRS). The second group performed the RMT by using IRS and the ADIM by using a Stabilizer. The exercises were conducted over four days. The pulmonary function was evaluated using the spirometer to measure the force exploratory volume in 1 second ($FEV_1$) and forced vital capacity (FVC). Measurements were conducted on the first day and the last day. A paired-t test was used for pre-post changes and the change rates in FVC and $FEV_1$ among each group were investigated by a one-way ANOVA. The findings of the the study were as follows: 1) There were significant differences of FVC and $FEV_1$ between pre and post in the two training groups (p<.05) 2) There was no significant difference of the change ratio the FVC and $FEV_1$ between the RMT group and RMT with ADIM group. Therefore, it is concluded that respiratory muscle and ADIM training, combined with two methods of treatment would suggest positive evidence for improving pulmonary function.

• 대한통합의학회지
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• 제12권1호
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• pp.83-96
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• 2024

Purpose : This study was conducted to determine the effects of a brain spinning program on cognitive function, body composition, health related fitness and physical self-efficacy of children and adolescents. Methods : This study, 34 children and adolescents were selected and divided into two groups : the exercise group (n=16), which received a brain spinning program and the control group (n=16), which did not receive any exercise program. The program was conducted for 30 minutes three times a week for 4 weeks, and the cognitive function, body composition, health related fitness and physical self-efficacy were measured both before and after the program. Results : The exercise group, which received a brain spinning program showed a significant increase in short-term memory (p<.05) and working memory (p<.01), and muscle mass increased significantly only in the exercise group (p<.05). In addition, left grip strength increased in the exercise group (p<.01), and the maximum oxygen intake decreased significantly only in the control group (p<.05), and Sit-forward bend increased significantly only in the exercise group (p<.01). Physical self-efficacy significantly increased only in the exercise group (p<.05). Conclusion : In summary, short-term memory, cognitive efficiency, working memory, muscle mass, left grip strength, maximum oxygen intake, and left forward bending in children and adolescents significantly increased after the 4-week brain spinning program. However, the control group that was not provided with the 4-week brain spinning program showed a significant increase in body weight and a significant decrease in maximum oxygen intake. In conclusion, the 4-week brain spinning program has positive effects on short-term memory, cognitive function, muscle mass, muscle strength, cardiorespiratory endurance, flexibility, and physical self-efficacy.

• 기본간호학회지
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• 제14권4호
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• pp.466-473
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• 2007

Purpose: The purpose of this study was to identify effects of pelvic floor muscle exercise on sexual function and to present basic information on promoting sexual function for employed middle-aged women. Method: Data were collected from July to September, 2005 from a sample of 25 conveniently selected middle-aged working women from B city. For personal reasons, 10 dropped out, leaving 15 women who were treated with the exercise for 6 weeks. Outcome measures on sexual function were assessed by a self-report questionnaire based on the Female Sexual Function Index(Rosen et al, 2000 and translated by Kim, 2004). Cronbach ${\alpha}'s $ for the two studies were .82 and .96 respectively and for this study, .81. Descriptive statistics and Wilcoxon signed rank test were used to analyze the data. Results: The mean score for sexual function was 21.42(range 2-36). There were significant improvements in total sexual function, and 4 sub-scales of sexual function, sexual arousal, vaginal lubrication, orgasm, and coital pain. No significant improvements in sexual desire or sexual satisfaction were found. Conclusion: The small sample means findings must be interpreted with caution, but do suggest that pelvic floor muscle exercise could be an effective exercise for improvement of sexual function.

• 재활간호학회지
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• 제9권1호
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• pp.42-48
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• 2006

Purpose: The purpose of this study was to explore the effect of Tai Chi exercise on pain, balance, gait and physical function of patients with low back pain. Method: This study was designed one group pretest-posttest design. Tai Chi exercise was conducted by researcher and carried out for sixty minutes per one time and two times a week for six weeks. The subjects of this study consisted of 23 low back patients. Using the SPSS win 10.0 program was used for data analysis, which included frequency, percentage and paired t-test. Result: Tai Chi exercise decreased pain, improved balance and gait, increased physical function(back muscle strength, leg muscle strength and flexibility). Conclusion: The results suggested Tai Chi exercise can be effective nursing intervention to improve pain, balance, gait and physical function of patients with low back pain.

• 대한통합의학회지
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• 제5권3호
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• pp.49-55
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• 2017

Purpose: The purpose of this study was to investigate effect of open kinetic chain exercise on the motor function of the lower limb in middle school soccer players. Method: The subjects consisted of 14 soccer players who attend middle school in Gwangju. All subjects received open kinetic chain exercise for 3 weeks. The muscle strength of the ankle was measured by a commander muscle tester. Postural control ability was measured using a hopping test. All measurements for each subject were conducted pre-intervention and 3 weeks post-intervention. Result: There were significant differences post-intervention in the muscle strength and-the postural control ability of the open kinetic chain exercise group(p<.05). Conclusion: Open kinetic chain exercise had a significant positive effect on the motor function of the lower limb in soccer players. Therefore, open kinetic chain exercise may prevent and resolve injury with careful management while soccer players are training or playing games. It could be helpful to extend the lives of athletes and improve their records.

• 대한물리의학회지
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• 제18권3호
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• pp.85-97
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• 2023

PURPOSE: This study analyzed the effectiveness of respiratory exercise in stroke patients conducted in Korea over the past 10 years (2012-2023). METHODS: Using the RISS, KCI, KISS, and NDSL databases, previous studies on stroke and respiratory exercise were searched, and relevant articles were collected following the PRISMA guidelines. Twelve articles were selected, and the quality of the studies was evaluated using the PEDro scale. RESULTS: Twelve studies were selected, and the qualitative evaluation of these studies showed that five articles received a score of six out of 10, while five articles received a score of five. The remaining two articles received scores of four and three, respectively. The intervention duration for respiratory exercise ranged from 20 to 30 minutes per session, with a frequency of three to five sessions per week, conducted over a period of three to eight weeks. These results indicated that respiratory exercise effectively improved the respiratory function, physical function, and respiratory muscle activation in stroke patients. CONCLUSION: Respiratory exercise was reported to have a positive affect the respiratory function, physical activity, and respiratory muscle activation in stroke patients.

• BMB Reports
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• 제49권6호
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• pp.303-304
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• 2016

Myoblast fusion is important for skeletal muscle formation. Even though the knowledge of myoblast fusion mechanism has accumulated over the years, the initial signal of fusion is yet to be elucidated. Our study reveals the novel function of a phosphatidylserine (PS) receptor, stabilin-2 (Stab2), in the modulation of myoblast fusion, through the recognition of PS exposed on myoblasts. During differentiation of myoblasts, Stab2 expression is higher than other PS receptors and is controlled by calcineurin/NFAT signaling on myoblasts. The forced expression of Stab2 results in an increase in myoblast fusion; genetic ablation of Stab2 in mice causes a reduction in muscle size, as a result of impaired myoblast fusion. After muscle injury, muscle regeneration is impaired in Stab2-deficient mice, resulting in small myofibers with fewer nuclei, which is due to reduction of fusion rather than defection of myoblast differentiation. The fusion-promoting role of Stab2 is dependent on its PS-binding motif, and the blocking of PS-Stab2 binding impairs cell-cell fusion on myoblasts. Given our previous finding that Stab2 recognizes PS exposed on apoptotic cells for sensing as an "eat-me" signal, we propose that PS-Stab2 binding is required for sensing of a "fuse-me" signal as the initial signal of myoblast fusion.

• 한국정밀공학회지
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• 제22권6호
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• pp.207-212
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• 2005

The purpose of this work is to develop the FES controller that can cope with the muscle fatigue which is one of the most important problems of current FES (Functional Electrical Stimulation). The feasibility of the proposed FES controller was evaluated by simulation. We used a fitness function to describe the effect of muscle fatigue and recovery process. The FES control system was developed based on the biological neuronal system. Specifically, we used PD (Proportional and Derivative) and GC (Gravity Compensation) control, which was described by the neuronal feedback structure. It was possible to control of multiple joints and muscles by using the phase-based PD and GC control method and the static optimization. As a result, the proposed FES control system could maintain the cycling motion in spite of the muscle fatigue. It is expected that the proposed FES controller will play an important role in the rehabilitation of SCI patient.

• 대한통합의학회지
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• 제7권1호
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• pp.113-124
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• 2019

Purpose : The purpose of this study is to investigate the effect of strengthening program for improving the muscle strength and body function in rehabilitation of patients with stroke Methods : We found the 15 precedent studies at online portal site of "Korea education and Research information service" and found 5 precedent studies at "Pubmed". We analyzed and describe the total 19 studies involving national and international research. Results : The strengthening exercise was adapted to lower extremities and trunk muscle of participants and the isokinetic (concentric and eccentric) exercise was most of exercise type and then manual isometric exercise, functional activities, progressive task oriented resistance exercise, PNF pattern exercise was following. The studies reported that the strengthening program increased target muscle strength and improved balance capacity and walking function for the participants positively. Conclusion : Conclusionally the several strengthening program can be the intervention to increase the muscle strength without increasing spasticity for patients with stroke. We think that the strengthening of lower extremities an improve balance capacity and walking ability and it can use the intervention to change the quality of life in patients with stroke. More than 3weeks strength program might be effectiveness, in case of acute patients with stroke, the improving of muscle strength is available but need to study for improving balance and walking capacity more in the future.