• 구강회복응용과학지
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• 제23권2호
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• pp.171-178
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• 2007

Botulinum toxin type A (BTX-A) has a local effect at the neuromuscular junction by blocking acetylcholine release and thus causing paralysis and atrophy of the affected muscles. In dentistry, Botulinum toxin type A(BTX-A) is used for the treatment of masseteric hypertrophy, temporomandibular disorder, and severe bruxism related neurologic disorder. We hypothesized that the muscle atrophy after BTX-A injection into masseter muscle in growing rats, could affect the jaw growth. The purpose of this study was to determine the effects of the BTX-A injected into the masseter muscle on the jaw growth in rats. Rats were divided into four groups(group 1; control group, group 2; saline injection group, group 3; BTX-A injection group, group 4; baseline control group). Group 4 was sacrificed at the beginning of the experiment to provide baseline values of jaw measurements. The weight, length and width of jaw in those groups were measured every weeks. This study reported that the mandibular body length, condylar length, coronoid process length, anterior region height, coronoid process height and condylar height of the jaw in BTX-A injection group were shorter than those of the control and saline injection groups(P<0.05). In conclusion, BTX-A injected into the masseter muscle may affect the undergrowth of the jaw in rats.

• Journal of Oral Medicine and Pain
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• 제38권2호
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• pp.143-147
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• 2013

측두하악장애 중 개구제한은 일반적으로 저작근, 측두하악관절의 통증, 비정복성 관절원판변위, 측두하악관절의 유착이나 강직, 저작근의 근경축 등에 의해 발생한다. 하지만 이비인후과적인 질환, 신경 및 혈관질환, 종양, 염증, 감염 등에 의해 측두하악장애와 유사한 통증 및 개구제한이 유발 될 수 있다. 따라서 병력 조사 및 임상 검사 시 이러한 이차적 질환에 대한 고려가 필요하다. 특히 초진 시 전형적인 측두하악장애의 소견을 보인다고 할지라도 적절한 치료 및 환자의 자기 관리에도 불구하고 증상의 호전이 없거나 지속적인 악화 소견을 보이는 경우에는 염증, 감염, 종양 등의 가능성에 관한 포괄적인 재평가가 필수적이다. 본 증례에서는 제 3 대구치의 치근단 농양이 익돌하악간극(pterygomandibular space)으로 확산되어 발생한 내익돌근(medial pterygoid muscle)의 통증 및 개구제한에 관하여 경험하였기에 이를 보고하고자 한다.

• 대한치과보철학회지
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• 제27권1호
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• pp.103-121
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• 1989

The purpose of this study was to investigate the influence of balancing interference on the activity of masticatory muscles and condylar path. Eight dental students of Won Kwang University without any symptoms of temporomandibular disorder and occlusal interferences, were selected for this study, The balancing interference was provided by construction and cementation of cast metal crowns on the upper and lower first molars. For the measurement of muscle activity, bioelectric processor (EM2, Myotronic Res., Inc., U.S.A.) was used and for the condular path, computerized electronic pantograph (Pantronics, Denar Corp., U.S.A.) was used and the myographic recordings were taken bilaterally from the anterior temporal, masseter and digastric muscles on rest position and on functions. These experimental procedures were done before cementation of experimental crown, three days after cementation of experimental crown, one week after, two weeks after and then one week after removal of experimental crown. The results are as follows: 1. The PRI score was increased at three days after application of balancing interference, and decreased at two weeks after. 2. Three subjects showed mild symptom of temporomandibular disorder at three or four days after application of interference, but the symptom was subsided in one or two weeks after application of interference. 3. One week after application of balancing interference, the activity of ipsilateral anterior temporal muscle in four subjects was decreased on gum chewing at experimental site. 4. Three days after application of balancing interference, the activity of ipsilateral anterior temporal muscle in three subjects was increased on gum chewing at non-experimental site. 5. The influence of balancing interference on the activity of anterior temporal, masseter and gigastric muscle was not prominent.

• Journal of Oral Medicine and Pain
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• 제30권2호
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• pp.239-246
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• 2005

본 연구는 측두하악장애환자와 정상인 간 그리고 측두하악장애환자의 분류에 따른 하악과두와 하악지 비대칭지수를 파노라마 방사선사진에서 비교하여 측두하악장애환자의 진단 및 치료계획 수립에 도움이 되고자 본 연구를 시행하였다. 측두하악장애환자 120명과 정상인 30명의 파노라마 방사선사진을 촬영후, 투사도를 작성하였다. 그리고 파노라마 방사선사진 계측항목 계측치의 평균값과 표준편차를 측두하악장애환자와 정상인으로 구분하여 산출한 다음 비대칭지수식을 이용하여 비대칭지수를 산출하여 양군 간의 비교분석을 시행하여 다음과 같은 결과를 얻었다. 1. 측두하악장애군과 대조군 간 하악과두 수직비대칭지수는 유의한 차이를 보였으나, 하악지 수직비대칭지수에서는 유의한 차이를 보이지 않았다. 2. 관절장애군과 근육장애군의 하악과두 수직비대칭지수는 대조군에 비해 더 크게 나타났지만, 관절장애군과 근육장애군 간의 하악과두 수직비대칭지수는 유의한 차이를 보이지 않았다. 3. 관절장애군, 근육장애군, 그리고 대조군 간의 하악지 수직비대칭지수 비교에서는 군간 유의한 차이를 보이지 않았다. 4. 관절원판변위군, 정복성관절원판전위군, 그리고 비정복성관절원판전위군 간의 하악과두 그리고 하악지 수직비대칭지수 비교에서는 유의한 차이를 보이지 않았다. 5. 하악과두와 하악지 수직비대칭지수 모두 연령증가와 관련이 없었다. 이상의 결과는 측두하악장애군이 정상인에 비해 하악과두 수직비대칭지수가 높게 나타나, 이러한 차이가 측두하악장애와 관련이 있음을 시사하였다. 따라서 파노라마 방사선사진을 이용한 하악과두 수직비대칭지수 측정은 측두하악장애 진단과 치료시 고려해야 할 중요한 부분으로 사료된다.

• 근관절건강학회지
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• 제14권1호
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• pp.61-69
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• 2007

Purpose: The purpose of the study is to investigate the degree of fatigue and its related factors in women with rheumatoid arthritis. Method: The subjects were 143 patients with rheumatoid arthritis. Data were collected by questionnaires including Multi-Dimensional Assessment of Fatigue(Tack, 1991), Korean Health Assessment Questionnaire(Bae et al., 1991), numeric scale of pain(Lee & Song, 1987), Center for Epidemiologic StudiesDepression, and Korean Sleep Scale(Oh, et al., 1998). The data were analyzed by SPSS WIN 12.0 program using descriptive statistics, Pearson Correlation, and Stepwise Multiple Regression. Result: The result were as follows. 1. The scores of fatigue of subjects averaged $4.95{\pm}1.83$, degree of fatigue was $5.85{\pm}1.98$, and influence of fatigue was $4.04{\pm}2.09$. 2. The mean score of the degree of physical dysfunction, pain, sleep disorder, and depression were $1.42{\pm}0.38,\;8.15{\pm}3.58,\;1.86{\pm}0.67,\;and\;1.85{\pm}0.46$ points respectively. 3. The subject's total fatigue score, physical dysfunction, pain, sleep disorder, and depression was correlated positively(r=.44, r=.28, r=.29, r=.27, p< .01). 4. The main influencing factors on the fatigue were physical dysfunction and sleep disorder. These two main variables made it possible to explain 23.0% of the variance in fatigue. Conclusion: Therefore, nursing interventions for fatigue experienced women with rheumatoid arthritis would be focused to decrease physical dysfunction and sleep disorder.

• 대한후두음성언어의학회지
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• 제32권3호
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• pp.124-129
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• 2021

Background and Objectives This study compares Vocal Fatigue Index (VFI) scores according to the presence or absence of external laryngeal tension in hyperfunctional voice disorder. And through this, it is to confirm the usefulness of VFI to hypertension of extrinsic laryngeal muscles. Materials and Method The subjects were 61 female diagnosed with hyperfunctional voice disorder (hypertension group 41, non-hypertension group 20). The author palpated extrinsic laryngeal muscles for evaluation of hypertension and classified them as the presence or absence. The voice measurements were jitter, shimmer, Korean-Voice Handicap Index-10 (K-VHI-10), and Korean-Vocal Fatigue Index (K-VFI). The voice compared were according to the diagnosis and presence of hypertension only for patients with hyperfunctional voice disorder. Results As a result of comparing the voice measurement according to the presence or absence of hypertension, there was no significant difference in the acoustic variables, K-VHI-10 and K-VFI-Total, K-VFI-Fatigue. Whereas, K-VFI-Physical (p=0.006) and K-VFI-Rest (p=0.022) were significantly higher in the hypertension group. Conclusion These results indicate that the hypertension group has more physical discomfort and less voice recovery than the group without hypertension. It means that K-VFI can measure the physical discomfort and limitations of voice recovery due to hypertension of the external laryngeal muscle. The VFI can be used as one of the methods to evaluate the hypertension of the external laryngeal muscle in Hyperfunctional voice disorder.

• 대한물리의학회지
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• 제2권1호
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• pp.11-20
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• 2007

Purpose : The purpose of this study was to evaluate effects of shoulder girdle stability exercise on upper extremity muscle strength. Methods : Subjects were consist of 20 people who had no disorder of upper extremity from 20 to 27 years of age during 6 weeks from April 3, 2006 to May 14. Ten of all subjects exercised muscles which stabilize to shoulder girdle for 30 minutes during 6 weeks. Biodex was used to measure upper extremity muscle strength. Results : There are increasing of shoulder flexion and extension on average torque but no statistically significant difference between pre-exercise and post-exercise. Conclusion : There are no severe difference between exercise group and non-exercise group on muscle strength.

• Journal of Oral Medicine and Pain
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• 제35권4호
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• pp.275-281
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• 2010

가쪽날개근은 턱의 기능을 수행하는데 기본적인 저작근 중의 하나이다. 이 근육은 저작계의 심부에 위치하기 때문에 손가락을 이용한 촉진검사가 어려우며 그 결과도 신뢰할 만하지 못하다. 이러한 이유로 임상의에게 가쪽날개근에 이환된 근육통 질환을 진단하는 것은 쉽지 않은 문제이다. 근육내 국소마취 주사는 통증의 근원지를 감별하는 목적으로서 가쪽날개근을 검사하는 효과적인 방법이 될 수 있다. 또한 근육통을 즉각적으로 제거함으로써 근육을 전체 길이만큼 신장하는데 도움을 줄 수 있다. 저자들은 근육내 국소마취 주사를 이용하여 가쪽날개근의 근육통을 성공적으로 진단하고 치료한 두 증례를 보고하고자 한다.

• Journal of Ginseng Research
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• 제48권1호
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• pp.12-19
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• 2024

Skeletal muscle (SM) is the largest organ of the body and is largely responsible for the metabolism required to maintain body functions. Furthermore, the maintenance of SM is dependent on the activation of muscle satellite (stem) cells (MSCs) and the subsequent proliferation and fusion of differentiating myoblasts into mature myofibers (myogenesis). Natural compounds are being used as therapeutic options to promote SM regeneration during aging, muscle atrophy, sarcopenia, cachexia, or obesity. In particular, ginseng-derived compounds have been utilized in these contexts, though ginsenoside Rg1 is mostly used for SM mass management. These compounds primarily function by activating the Akt/mTOR signaling pathway, upregulating myogenin and MyoD to induce muscle hypertrophy, downregulating atrophic factors (atrogin1, muscle ring-finger protein-1, myostatin, and mitochondrial reactive oxygen species production), and suppressing the expressions of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in cachexia. Ginsenoside compounds are also used for obesity management, and their anti-obesity effects are attributed to peroxisome proliferator activated receptor gamma (PPARγ) inhibition, AMPK activation, glucose transporter type 4 (GLUT4) translocation, and increased phosphorylations of insulin resistance (IR), insulin receptor substrate-1 (IRS-1), and Akt. This review was undertaken to provide an overview of the use of ginseng-related compounds for the management of SM-related disorders.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제28권5호
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• pp.358-363
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• 2002

Purpose : Authors attempted to evaluate the effect on explanation of pathogenesis and stress management as the initial care of temporomandibular disorders. Materials and methods : The materials were 634 patients with temporomandibular disorder, who had been referred to our Department of Dentistry, Wonju Christian Hospital during recent 5 years. We examined about clinical aspects of temporomandibular disorders, such as, major signs of temporomandibular joint disorder, life environment and habits, radiological findings of temporomandibular joint and electromyography of masseter muscle. The patients were treated by explanation of TMJ pathogenesis and stress management. After that, the patient were evaluated about the effect in third week. Results : The result was more favorable (96.5% success rate) without intolerable signs of temporomandibular joint disorder. Conclusion : The explanation of TMJ pathogenesis and stress management were thought as the very effective care in management of patients with temporomandibular disorder.