• The Korean Journal of Nuclear Medicine
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• v.16 no.1
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• pp.15-22
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• 1982

To evaluate the diagnostic usefulness of radioisotope bone scan and clinical activity of myositis, bone scan using $^{99m}Tc-Methylene$ diphosphonate was serially done before and after treatment with prednisolone in 10 patients with well-documented dermatomyositis-polymyositis. The observed results were as follows. 1. In all 10 patients before treatment with prednisolone, the bone scans showed evidence of increased muscle uptake. Muscle uptake was markedly increased in 4 patients, moderately increased in 3 patients and minimally increased in 3 patients. 2. The site of increased muscle uptake was consistent with the site of clinically involved muscle which was weak and tender. 3. The degree of muscle uptake correlated with the severity of the muscle weakness and tenderness at the scan was done. In all 10 patients treated with high dose prednisolone, muscle uptake was decreased following therapy. Above results suggest the radioisotope bone scanning may be useful in the diagnosis and treatment of patient with dermatomyositis-polymyositis.

• Journal of Chest Surgery
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• v.26 no.3
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• pp.219-223
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• 1993

Myasthenia gravis is disorder of neuromuscular transmission that is characterized by weakness and fatigue of voluntary muscle. A clinical study of 18 cases of myasthenia gravis was performed at Chosun university college of medicine, from 1988 to 1992. Maximal thymectomy was performed in 7 cases and only medical treatment had been done in 11 cases.

• The Journal of Internal Korean Medicine
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• v.43 no.5
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• pp.891-900
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• 2022

Purpose: The purpose of this paper is to report the improvement of a patient with amyotrophic lateral sclerosis after long-term combined Korean medical treatment. Methods: A patient diagnosed with amyotrophic lateral sclerosis was treated with herbal medicine, acupuncture, pharmacopuncture, moxibustion, and rehabilitation for four separate hospital stays. To evaluate their respiratory discomfort and limb weakness, we used Manual Muscle Testing, the Pulmonary Function Test, and the Korean Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised. Results: The weakness of the muscles of the lower extremities and respiratory function was improved. Conclusion: We consider that combined Korean medicine treatments might be an effective treatment for muscle weakness and respiratory discomfort of amyotrophic lateral sclerosis. To verify the effectiveness of these treatments, further research is required.

• Herbal Formula Science
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• v.24 no.3
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• pp.153-161
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• 2016

Chronic alcoholic myopathy is one of the most common skeletal muscle disorders. It is characterized by a reduction in the entire skeletal musculature, skeletal muscle weakness, and difficulties in gait. Patients with alcoholic hepatitis and cirrhosis have severe muscle loss that contributes to worsening outcome. Although the myopathy selectively affects Type II (fast twitch, glycolytic, anaerobic) skeletal muscle fibers, total skeletal musculature is reduced. The severity of the muscle atrophy is proportional to the duration and amount of alcohol consumed and leads to decreased muscle strength. The mechanisms for the myopathy are generally unknown but it is not due to overt nutritional deficiency, nor due to either neuropathy or severe liver disease. Skeletal muscle mass and protein content are maintained by a balance between protein synthesis and breakdown and in vivo animal models studies have shown that ethanol inhibits skeletal muscle protein synthesis. Daekumeumja is a traditional Korean medicine that is widely employed to treat various alcohol-induced diseases. Muscle diseases are often related to liver diseases and conditions. The main objective of this study was to assess that Daekumeumja extract could have protective effect against alcoholic myopathy in a Sprague-Dawley rat model. Rats were orally given 25% ethanol (5ml/kg, body weight) for 8 weeks. After 30 minutes, rats were administrated with Daekumeumja extract. Controls were similarly administrated with the vehicle alone. The weights of gastrocnemius, soleus and plantaris muscles were assessed and the morphologic changes of gastrocnemius and plantaris muscles were also assessed by hematoxylin and eosin staining. In results, The muscles from ethanol treated rats displayed a significant reduction in muscle weight and average cross section area compared to Normal group. Daekumeumja extract treated group showed increased muscle weight and muscle fiber compared to the ethanol treated group. It was concluded that Daekumeumja extract showed ameliorating effects on chronic alcohol myopathy in skeletal muscle.

• Research in Community and Public Health Nursing
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• v.16 no.2
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• pp.186-195
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• 2005

Purpose: This study aims to understand andropause symptoms and life satisfaction among middle-aged Korean men. Method: The subjects were selected among men in their middle age who visited one of two university hospitals or a convalescent center in Seoul. Korea. Eight items were used to measure their andropause symptoms. Life Satisfaction Index-Z was used to measure life satisfaction. Results: Major symptoms related andropause. in the order of frequency, include memory loss, muscle weakness. powerlessness and impotence. Among the subjects. 62.5% smoked and 70% drank alcohol. and life satisfaction was generally moderate in the participants. Current smokers and alcohol drinkers reported a low level of life satisfaction. Diabetic patients and subjects who had powerlessness and hot flashes of andropause symptoms experienced a low level of life satisfaction. Muscle weakness was more frequent in current smokers, and powerlessness more in alcohol drinkers. Conclusion: This study's findings indicate that and ropause is one of major health concerns among middle-aged men. It reminds us of the smoking and alcohol drinking issues among middle-aged men. These findings show the necessity to improve strategies for nursing intervention in andropause symptoms and health risk behaviors.

• Journal of Korean Medicine Rehabilitation
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• v.25 no.1
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• pp.95-101
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• 2015

Objectives The purpose of this case is to report the improvement after Korean medical combined treatment about patient with Guillain-Barre syndrome. Methods We treated patient using electroacupuncture, moxibustion, herbal medication, and rehabilitation therapy for 59 days. Results The weakness of muscles of upper extremities were recovered to normal level, and the muscle power of lower extremities was improved enough to walking with walker. Conclusions We conclude that Korean medical combined treatment is an effective to improve the power of muscle having weakness. But there is a limit on this report due to sufficient number of case. Further studies will be needed.

• Archives of Plastic Surgery
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• v.49 no.3
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• pp.440-443
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• 2022

Spinal accessory nerve (SAN) palsy is typically a result of posterior triangle surgery and can present with partial or complete paralysis of the trapezius muscle and severe shoulder dysfunction. We share an atypical case of a patient who presented with SAN palsy following an injury sustained playing competitive volleyball. A 19-year-old right hand dominant competitive volleyball player presented with right shoulder weakness, dyskinesia, and pain. She injured the right shoulder during a volleyball game 2 years prior when diving routinely for a ball. On physical examination she had weakness of shoulder shrug and a pronounced shift of the scapula when abducting or forward flexing her shoulder greater than 90 degrees. Manual stabilization of the scapula eliminated this shift, so we performed scapulopexy to stabilize the inferior angle of the scapula. At 6 months postoperative, she had full active range of motion of the shoulder. SAN palsy can occur following what would seem to be a routine volleyball maneuver. This could be due to a combination of muscle hypertrophy from intensive volleyball training and stretch sustained while diving for a ball. Despite delayed presentation and complete atrophy of the trapezius, a satisfactory outcome was achieved with scapulopexy.

• Journal of The Korean Society of Clinical Toxicology
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• v.21 no.2
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• pp.151-155
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• 2023

Licorice is a perennial herb belonging to the legume family that mainly grows in northeastern China, Mongolia, Siberia, and other regions. It is used in traditional medicine in the form of dried roots in the East and the West. The main active component of licorice, glycyrrhizin, is known to produce mineralocorticoid effects when consumed chronically, which can lead to apparent mineralocorticoid excess syndrome. Herein, we present the case of a 72-year-old woman who was admitted to the emergency room with severe generalized weakness and difficulty keeping her neck upright, which had developed after daily consumption of licorice-infused water for the past 2 months. Blood tests revealed metabolic alkalosis and severe hypokalemia, and an electrocardiogram showed ventricular bigeminy. The patient was treated with daily potassium and spironolactone supplements, leading to a significant improvement in muscle strength after a week. One week later, the patient was discharged, showing rare ventricular premature contractions on electrocardiography, but with no specific complaints. Chronic licorice ingestion leading to hypokalemia and muscle weakness can be life-threatening, necessitating the discontinuation of the causative agent, close monitoring, and cautious supplementation of potassium and spironolactone as treatment.

• Physical Therapy Korea
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• v.22 no.3
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• pp.98-105
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• 2015

Muscular dystrophy is a hereditary musculoskeletal disorder caused by a mutation in the dystrophin gene. Duchenne muscular dystrophy (DMD) is one of the most common, and progresses relatively faster than other muscular dystrophies. It is characterized by progressive myofiber degeneration, muscle weakness and ultimately ambulatory loss. Since it is an X-linked recessive inheritance, DMD is mostly expressed in males and rarely expressed or less severe in females. The most effective measurement tool for DMD is magnetic resonance imaging (MRI), which allows non-invasive examination of longitudinal measurement. It can detect progressive decline of skeletal muscle size by measuring a maximal cross-sectional area of skeletal muscle. Additionally, other techniques in MRI, like $T_2$-weighted imaging, assess muscle damage, including inflammation, by detecting changes in $T_2$ relaxation time. Current MRI techniques even allow quantification of metabolic differences between affected and non-affected muscles in DMD. There is no current cure, but physical therapist can improve their quality of life by maintaining muscle strength and function, especially if treatment (and other forms of medical intervention) begins in the early stages of the disease.

• Physical Therapy Rehabilitation Science
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• v.11 no.2
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• pp.253-258
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• 2022

Objective: This study aimed to determine the effect of internal abdominis pressure(normal, hollowing and bracing) on trunk muscle activity during one leg bridge exercise. Design: Cross-sectional study. Methods: Thirteen healthy adults (9 men and 4 women) were instructed to perform Internal abdominal pressure(IAP) control(Normal, Hollowing, Bracing) during one leg bridge. Electromyography (EMG) data (% Maximum Voluntary Isometric Contraction, MVIC) were recorded three times on both sides of the participant's Internal Oblique(IO), Effector Spinae(ES), and Multifidus(MF) muscles and the average value was analyzed. Results: As a result, Abdominal bracing one leg bridge (BOLB) group and Abdominal hollowing one leg bridge (HOLB) group showed significantly increased muscle activation of bilateral internal oblique, erector spinae and multifidus activation compared to the Normal one leg bridge (NOLB) group (p<0.05). Abdominal hollowing one leg bridge (HOLB) group had a significant difference in bilateral Internal oblique muscle activation in compared to the NOLB group (p<0.05). Conclusions: Bilateral internal oblique, erector spinae, and multifidus muscles activation in healthy adults at one leg bridge exercise showed greater activation at abdominal bracing. Therefore, in this study, IAP control can be used as an indicator of choice to the dysfunction with trunk muscle weakness and corrective exercise subject's situation when the goal is to activate the trunk muscles by performing one leg bridge.